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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Ethyl (E)-crotonate Manufacturer/High quality/Best price/In stock

Cas:623-70-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hefei TNJ chemical industry co.,ltd

Superiority Service we can provide: 1. Mixed container: We can mix different items in one container. 2. Quality control: Before shipment, we can provide free sample for test. Inspection before shipping. 3. Packing: We can pack according to you

Good quality Ethyl crotonate//623-70-1

Cas:623-70-1

Min.Order:1 Metric Ton

Negotiable

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Ethyl Crotonate

Cas:623-70-1

Min.Order:1

Negotiable

Type:Other

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Wuhan Fortuna Chemical Co.,Ltd

CAS RN.: 623-70-1;10544-63-5 EINECS: 210-808-7;234-125-9 Molecular Weight:

Ethyl (E)-crotonate 623-70-1

Cas:623-70-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Antimex Chemical Limied

CAS 623-70-1 C6H10O2 Ethyl crotonate Physical State: Liquid Color: clear, colorless Odor: none reported pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 142.0 -

Ethyl crotonate CAS 623-70-1

Cas:623-70-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:623-70-1

Cas:623-70-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Ethyl crotonate

Cas:623-70-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Ethyl (E)-crotonate

Cas:623-70-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Ethyl (E)-crotonate Manufacturer

Cas:623-70-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermediate

Ethyl (E)-crotonate

Cas:623-70-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o

623-70-1

Cas:623-70-1

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Ethyl crotonate

Cas:623-70-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Vanz Pharm Co.,Ltd

ISO/factory/goodqualityAppearance:off white Storage:Dry,cool place Package:drum Application:active pharmaceutical ingredients Transportation:by air/sea/express Port:shenzhen/shanghai

Ethyl crotonate

Cas:623-70-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

trans-Ethyl crotonate

Cas:623-70-1

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Ethyl crotonate, 98%

Cas:623-70-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

factory directly supply CAS 623-70-1 with best price

Cas:623-70-1

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

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Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

Ethyl crotonate

Cas:623-70-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

Ethyl crotonate

Cas:623-70-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Ethyl crotonate//623-70-1 CAS NO.623-70-1 CAS NO.623-70-1 Application:Ethyl crotonate//623-70-1 CAS NO.623-70-1 CAS NO.623-70-1

Ethyl crotonate//623-70-1 CAS NO.623-70-1 CAS NO.623-70-1

Cas:623-70-1

Min.Order:0

Negotiable

Type:Other

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Hunan Longxianng Runhui Trading Co.,Ltd

Ethyl crotonate//623-70-1 CAS NO.623-70-1 CAS NO.623-70-1Appearance:powder Storage:Store at RT. Package:in foil bag or customized Application:Industrial Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport

Ethyl crotonate//623-70-1 CAS NO.623-70-1 CAS NO.623-70-1

Cas:623-70-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Ethyl crotonate 623-70-1

Cas:623-70-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Baoji Kano Phytochem Technology Co.,Ltd

Our Advantages 1>Professional quality control department 2>Strict inspection system for receiving inspection,in-process and finished products. 3>ISO quality system. 4>All of our service comply to CUSTOMER FIRST. Appearance:Color

High Quality Ethyl (E)-crotonate

Cas:623-70-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Amadis Chemical offer CAS#623-70-1;CAT#A833743

Cas:623-70-1

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

623-70-1 C6H10O2 Ethyl crotonate

Cas:623-70-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zhejiang Newfine Industry Co.,Ltd.

Zhejiang Newfine Industry Co.,Ltd. is a professional supplier of Aromatic Chemicals,Fragrance & Flavor use Chemicals,Pine Chemicals,Fine Chemicals,Food Additives and some Essential Oils. We have 12 years experience in this

Ethyl (E)-crotonate

Cas:623-70-1

Min.Order:1000 Kilogram

Negotiable

Type:Trading Company

inquiry

Changzhou Extraordinary Pharmatech co.,LTD

Changzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa

Ethyl trans-2-butenoate

Cas:623-70-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Watson International Ltd

Watson International Ltd' has a very strong R&D and technical capacity supported by FCAD's platform. The subsidiaries under FCAD Group have accumulated much know-how of different fine chemical branches. For example, Apnoke Scientific L

Ethylcrotonate

Cas:623-70-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen BaiFuchem Co.,Ltd

BaiFuChem is a Professional chemical raw material supplier in China, our main products include Biochemical , Pharma Intermediate and Organic chemical etc. BaiFuChem have wealth of products,experience , expertise and state-of-the-art

High quality Ethyl Crotonate

Cas:623-70-1

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Nanjing Chemlin Chemical Co., Ltd.

Compound sourcing ServicesAgency of testing serviceFactory audit serviceFounded in Dec. 1999, Nanjing Chemlin Chemical Industrial Co.,Ltd(CHEMLIN) has been covering the business scope from trading of chemicals to custom-synthesis & Manufacturing. Co

623-70-1

Cas:623-70-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Nanjing Sunsure Chemical Technology Co., Ltd

Nanjing Sunsure Chemical Technology Co., Ltd., established in 2009, has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of chemicals. Sunsure covers whole

Ethyl crotonate 623-70-1 supplier

Cas:623-70-1

Min.Order:1 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

3-(ethylthio)-butanoic acid, ethyl ester
90201-28-8

3-(ethylthio)-butanoic acid, ethyl ester

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With tetrabutylammomium bromide In ethanol electrolysis;98%
ethyl trans-2-methylthiirane carboxylate
107467-99-2

ethyl trans-2-methylthiirane carboxylate

CO

CO

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
di(rhodium)tetracarbonyl dichloride In benzene under 20685.9 Torr; for 18h; Ambient temperature;97%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

acetaldehyde
75-07-0

acetaldehyde

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With potassium carbonate In 1,4-dioxane at 25℃; for 2.2h;95%
With sodium hydride In tetrahydrofuran 1.) r.t., 1 h; 2.) -70 deg C then up to 0 deg C over 2 h;90%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 0.5h;
Stage #2: acetaldehyde In tetrahydrofuran; mineral oil at 0 - 20℃;
fac-tricarbonyl{1-ethoxy-1-oxo-2-butenyl-C(3),O}(triphenylphosphine)rhenium

fac-tricarbonyl{1-ethoxy-1-oxo-2-butenyl-C(3),O}(triphenylphosphine)rhenium

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With CF3CO2H In benzene-d6 React. at 25°C, 10 h.; Monitored by (1)H-NMR.;95%
ethyl α-bromo-α-trimethylsilylacetate
86294-63-5

ethyl α-bromo-α-trimethylsilylacetate

acetaldehyde
75-07-0

acetaldehyde

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
silver-graphite; zinc In tetrahydrofuran at -78℃; for 0.166667h;79%
ethanol
64-17-5

ethanol

(E)-but-2-enoic acid
107-93-7

(E)-but-2-enoic acid

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With sulfuric acid In benzene Heating;78.5%
With sulfuric acid; magnesium sulfate In benzene Heating; Yield given;
With phosphorus pentoxide 1.) 0-5 deg C, 2.) reflux, 3 h; Yield given. Multistep reaction;
With bis(2,2,2-trifluoroethoxy)diphenylsulfurane 1.) THF, -78 deg C, 2.) THF, -78 deg C; Yield given. Multistep reaction;
4-bromoethylbutanoate
2969-81-5

4-bromoethylbutanoate

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With bis(triphenylphosphine)nickel(II) chloride; n-butyllithium; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine In tetrahydrofuran; hexane Ambient temperature;77%
diethyl sulphite
623-81-4

diethyl sulphite

(E)-but-2-enoic acid
107-93-7

(E)-but-2-enoic acid

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
sulfuric acid In ethanol for 2h; Heating;73%
carbon monoxide
201230-82-2

carbon monoxide

sodium ethanolate
141-52-6

sodium ethanolate

allyl bromide
106-95-6

allyl bromide

A

ethyl 3-butenoate
1617-18-1

ethyl 3-butenoate

B

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
Na2PdCl4-dppe In ethanol at 50℃; for 2h;A 17%
B 72%
(E)-but-2-enoic acid
107-93-7

(E)-but-2-enoic acid

Fe(ClO4)3(CH3CH2OH)6/SiO2

Fe(ClO4)3(CH3CH2OH)6/SiO2

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
for 2h; Solid phase reaction; esterification;69%
(E)-crotonaldehyde diethyl acetal
63511-92-2

(E)-crotonaldehyde diethyl acetal

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With tert.-butylhydroperoxide; dipyridinium dichromate In dichloromethane for 7h; Ambient temperature;67%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
C-200 (barium hydroxide) In tetrahydrofuran; water for 0.166667h; Ambient temperature; sonication;61%
Vinyl bromide
593-60-2

Vinyl bromide

bromo(2-ethoxy-2-oxoethyl)zinc
5764-82-9

bromo(2-ethoxy-2-oxoethyl)zinc

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With tetrakis(triphenylphosphine)nickel(0) In N,N,N,N,N,N-hexamethylphosphoric triamide for 3h; Heating;55%
3-aminobutanoic acid ethyl ester
5303-65-1

3-aminobutanoic acid ethyl ester

4-chloro-2,2-dimethyl-2H-benzo[e][1,3]oxazine
74405-07-5

4-chloro-2,2-dimethyl-2H-benzo[e][1,3]oxazine

A

2,4-bis(2-hydroxyphenyl)-6-methylpyrimidine
82507-91-3

2,4-bis(2-hydroxyphenyl)-6-methylpyrimidine

B

ethyl 3-(2,2-dimethyl-2H-1,3-benzoxazin-4-ylamino)butylate

ethyl 3-(2,2-dimethyl-2H-1,3-benzoxazin-4-ylamino)butylate

C

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
at 150 - 160℃; for 4h;A 38%
B 10%
C n/a
at 150 - 160℃; for 4h; Product distribution; Mechanism;A 38%
B 10%
C n/a
(E)-but-2-enoic acid
107-93-7

(E)-but-2-enoic acid

(2,2-diethoxyvinylidene)triphenylphosphorane
21882-77-9, 53472-13-2

(2,2-diethoxyvinylidene)triphenylphosphorane

A

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

B

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

Conditions
ConditionsYield
In tetrahydrofuran for 3h; Ambient temperature;A 33%
B n/a
ethanol
64-17-5

ethanol

carbon monoxide
201230-82-2

carbon monoxide

3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

A

ethyl 3-butenoate
1617-18-1

ethyl 3-butenoate

B

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
carbonylchlorobis(triethylphosphine)rhodium(I) at 120℃; under 30002.4 Torr; for 4h;A 28%
B 12 % Turnov.
3-aminobutanoic acid ethyl ester
5303-65-1

3-aminobutanoic acid ethyl ester

4-chloro-2-methyl-2-methoxycarbonylmethyl-2H-1,3-benzoxazine
82507-98-0

4-chloro-2-methyl-2-methoxycarbonylmethyl-2H-1,3-benzoxazine

A

2-(2-hydroxyphenyl)-6-methyl-4(3H)-pyrimidinone
76467-22-6

2-(2-hydroxyphenyl)-6-methyl-4(3H)-pyrimidinone

B

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
at 170 - 180℃; for 3h;A 26%
B n/a
(Z)-2-{Methylsulfanyl-[(2,2,2-trifluoro-acetyl)-hydrazono]-methylsulfanyl}-but-2-enoic acid ethyl ester

(Z)-2-{Methylsulfanyl-[(2,2,2-trifluoro-acetyl)-hydrazono]-methylsulfanyl}-but-2-enoic acid ethyl ester

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With aluminium amalgam In diethyl ether; ethanol Ambient temperature;18%
2-butenoic acid
3724-65-0

2-butenoic acid

ethanol
64-17-5

ethanol

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With sulfuric acid
With sulfuric acid
ethyl 3-hydroxybutyrate
5405-41-4

ethyl 3-hydroxybutyrate

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With aluminum oxide at 325 - 350℃;
ethanol
64-17-5

ethanol

trans-chrotonyl chloride
625-35-4, 3488-22-0, 10487-71-5

trans-chrotonyl chloride

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

ethanol
64-17-5

ethanol

3-chloro-butyric acid ethyl ester
7425-48-1

3-chloro-butyric acid ethyl ester

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With sodium hydroxide at 0 - 5℃;
3-chloro-butyric acid ethyl ester
7425-48-1

3-chloro-butyric acid ethyl ester

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With ethanol; ammonia
3-methyl-1,4-diphenyl-1,2,3,4-tetrahydro-1,4-epoxido-naphthalene-2-carboxylic acid ethyl ester
872297-31-9

3-methyl-1,4-diphenyl-1,2,3,4-tetrahydro-1,4-epoxido-naphthalene-2-carboxylic acid ethyl ester

A

1,3-diphenylisobenzofuran
5471-63-6

1,3-diphenylisobenzofuran

B

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

ethyl 3-hydroxybutyrate
5405-41-4

ethyl 3-hydroxybutyrate

acetic anhydride
108-24-7

acetic anhydride

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
und Erhitzen des Reaktionsprodukts mit Kaliumacetat;
hydrogen ethyl malonate
1071-46-1

hydrogen ethyl malonate

acetaldehyde
75-07-0

acetaldehyde

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With piperidine; pyridine
diethyl ether
60-29-7

diethyl ether

2-methyl-butane-1,3,3-tricarboxylic acid triethyl ester
854462-99-0

2-methyl-butane-1,3,3-tricarboxylic acid triethyl ester

sodium ethanolate
141-52-6

sodium ethanolate

methyl iodide
74-88-4

methyl iodide

A

2,2-dimethylmalonic acid diethyl ester
1619-62-1

2,2-dimethylmalonic acid diethyl ester

B

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
unter Kuehlung;
2-bromobutyric acid ethyl ester
533-68-6

2-bromobutyric acid ethyl ester

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With N,N-diethylaniline
ethyl 3-butenoate
1617-18-1

ethyl 3-butenoate

A

ethyl (Z)-crotonate
6776-19-8

ethyl (Z)-crotonate

B

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With (isomerization); diethylamine In diethyl ether at 40℃; Kinetics; other catalysts;
ethyl iodide
75-03-6

ethyl iodide

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Conditions
ConditionsYield
With 18-crown-6 ether; potassium naphthalenide 1) THF, 20 deg C, 10 min; Yield given. Multistep reaction;
ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

1-nitrocyclohexane
1122-60-7

1-nitrocyclohexane

3-(1-nitro-cyclohexyl)-butyric acid ethyl ester

3-(1-nitro-cyclohexyl)-butyric acid ethyl ester

Conditions
ConditionsYield
With 2,5,8,9-tetraaza-1-phosphabicyclo[3.3.3]undecane 2,8,9-tris(1-methylethyl) In various solvent(s) at 20℃; for 4h; Michael addition;100%
ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

C26H38N2O4
810671-46-6

C26H38N2O4

C32H48N2O6
810671-55-7

C32H48N2O6

Conditions
ConditionsYield
Stage #1: C26H38N2O4 With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 1h;
Stage #2: ethyl (E)-crotonate In tetrahydrofuran at -78 - -20℃; for 2h; Michael addition;
100%
anthracen-9(10H)-one
90-44-8

anthracen-9(10H)-one

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

3-(10-oxo-9,10-dihydro-anthracen-9-yl)-butyric acid ethyl ester

3-(10-oxo-9,10-dihydro-anthracen-9-yl)-butyric acid ethyl ester

Conditions
ConditionsYield
With lithium perchlorate; triethylamine In diethyl ether for 16h; Michael addition;100%
lithium hydroxide monohydrate

lithium hydroxide monohydrate

Methyl thioglycolate
2365-48-2

Methyl thioglycolate

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

4-ethoxycarbonyl-2-methylthiolan-3-one
80289-37-8

4-ethoxycarbonyl-2-methylthiolan-3-one

Conditions
ConditionsYield
In ethyl acetate; N,N-dimethyl-formamide100%
N-((1S)-1-phenylethyl)hydroxylamine
53933-47-4

N-((1S)-1-phenylethyl)hydroxylamine

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

C14H21NO3
912650-23-8

C14H21NO3

Conditions
ConditionsYield
In tetrahydrofuran100%
nitromethane
75-52-5

nitromethane

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

3-methyl-4-nitrobutyric acid ethyl ester
2985-50-4

3-methyl-4-nitrobutyric acid ethyl ester

Conditions
ConditionsYield
With 2,5,8,9-tetraaza-1-phosphabicyclo[3.3.3]undecane 2,8,9-tris(1-methylethyl) In various solvent(s) at -63℃; for 0.15h; Michael addition;99%
With N,N,N',N'-tetramethylguanidine for 18h;99.2%
With N,N,N',N'-tetramethylguanidine at 20℃; for 24h; Michael addition;91%
With N,N,N',N'-tetramethylguanidine at 20℃; for 24h; Inert atmosphere;82%
dimethyl amine
124-40-3

dimethyl amine

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

3-Dimethylamino-buttersaeureethylester
85118-28-1

3-Dimethylamino-buttersaeureethylester

Conditions
ConditionsYield
With carbon dioxide for 1h; Ambient temperature;99%
p-methoxybenzyl chloride
824-94-2

p-methoxybenzyl chloride

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

ethyl 4-(4-methoxyphenyl)-3-methylbutanoate
183134-81-8

ethyl 4-(4-methoxyphenyl)-3-methylbutanoate

Conditions
ConditionsYield
Stage #1: p-methoxybenzyl chloride With iodine; magnesium In tetrahydrofuran for 2h;
Stage #2: With copper(l) iodide; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran at -78℃; for 0.833333h;
Stage #3: ethyl (E)-crotonate With chloro-trimethyl-silane In tetrahydrofuran at -30℃; for 18h;
99%
With copper(l) iodide; chloro-trimethyl-silane; N,N,N,N,-tetramethylethylenediamine; iodine; magnesium Yield given. Multistep reaction;
ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

thioacetic acid
507-09-5

thioacetic acid

ethyl 3-(acetylthio)butanoate
92065-74-2

ethyl 3-(acetylthio)butanoate

Conditions
ConditionsYield
With indium(III) chloride In 1,2-dichloro-ethane at 60℃; for 18h; Inert atmosphere;99%
2-aminophenylboronic acid
5570-18-3

2-aminophenylboronic acid

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

4-methyl-3,4-dihydroquinolin-2(1H)-one
30696-28-7

4-methyl-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
With [Rh(OH)(cod)]2; potassium carbonate In water at 50℃; for 5h; Inert atmosphere;99%
ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

ethyl 2,3-dibromobutyrate
609-11-0

ethyl 2,3-dibromobutyrate

Conditions
ConditionsYield
With bromine In tetrachloromethane for 2h; Heating;98%
With bromine In tetrachloromethane for 24h; Heating;78%
With N-Bromosuccinimide In 1,4-dioxane; water
butyraldehyde
123-72-8

butyraldehyde

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

3-methyl-4-oxo-heptanoic acid ethyl ester
67893-05-4

3-methyl-4-oxo-heptanoic acid ethyl ester

Conditions
ConditionsYield
With triisopropylsilanethiol; trans-di-O-tert-butyl hyponitrite In 1,4-dioxane at 60℃; for 3.5h;98%
trimethyl(4-mercaptomethylphenyl)silane
57337-85-6

trimethyl(4-mercaptomethylphenyl)silane

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

3-(4-trimethylsilanyl-benzylsulfanyl)-butyric acid ethyl ester
497181-03-0

3-(4-trimethylsilanyl-benzylsulfanyl)-butyric acid ethyl ester

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 0.5h; Michael addition;98%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 0.5h; Michael addition;98%
N-(diphenylmethylene)glycine tert-butyl ester
81477-94-3

N-(diphenylmethylene)glycine tert-butyl ester

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

2-tert-butyl 4-ethyl 3-methyl-5,5-diphenylpyrrolidine-2,4-dicarboxylate

2-tert-butyl 4-ethyl 3-methyl-5,5-diphenylpyrrolidine-2,4-dicarboxylate

Conditions
ConditionsYield
With 4 A molecular sieve; calcium bis-iso-propoxide; 2,2'-methylene bis((4S)-4-phenyl-2-oxazoline) In tetrahydrofuran at -30℃; for 12h; Michael addition;98%
4-bromo-N-cyclohexyl-N-isobutyl-2-nitroaniline

4-bromo-N-cyclohexyl-N-isobutyl-2-nitroaniline

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

ethyl (E)-3-(4-(cyclohexyI(isobutyI)arnino)-3-nitrophenyl)but-2-enoate

ethyl (E)-3-(4-(cyclohexyI(isobutyI)arnino)-3-nitrophenyl)but-2-enoate

Conditions
ConditionsYield
With dichlorobis(tri-O-tolylphosphine)palladium; tetrabutylammomium bromide; triethylamine In N,N-dimethyl-formamide at 110℃; Inert atmosphere;98%
With tetrakis(tris(2-methyl)phenyl)phosphinepalladium; tetrabutylammomium bromide; triethylamine In N,N-dimethyl-formamide at 110℃; Inert atmosphere;81%
ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

benzylamine
100-46-9

benzylamine

ethyl 3-(benzylamino)butanoate
6335-80-4

ethyl 3-(benzylamino)butanoate

Conditions
ConditionsYield
With ytterbium(III) triflate In tetrahydrofuran for 6h; Ambient temperature;97%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile for 20h; Kinetics; Solvent; Temperature; Time; Michael Addition; Reflux;86%
In ethanol at 20℃; for 38h;84.3%
BuMnCl
88626-90-8

BuMnCl

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

3-methyl-heptanoic acid ethyl ester
37492-08-3

3-methyl-heptanoic acid ethyl ester

Conditions
ConditionsYield
With chloro-trimethyl-silane; copper(l) chloride In tetrahydrofuran for 1h; 0 to 20 deg C;97%
ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

((R)-1-Phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amine
192655-92-8

((R)-1-Phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amine

(R)-3-[((R)-1-Phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amino]-butyric acid ethyl ester
192655-84-8

(R)-3-[((R)-1-Phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amino]-butyric acid ethyl ester

Conditions
ConditionsYield
97%
2-(4-(benzyloxy)phenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine

2-(4-(benzyloxy)phenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

ethyl 3-(2-(4-(benzyloxy)phenyl)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)butanoate

ethyl 3-(2-(4-(benzyloxy)phenyl)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)butanoate

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In 1-methyl-pyrrolidin-2-one at 140℃; for 1h; Michael Addition;97%
piperidin-2-one
675-20-7

piperidin-2-one

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

3-(2-Oxo-piperidin-1-yl)-butyric acid ethyl ester

3-(2-Oxo-piperidin-1-yl)-butyric acid ethyl ester

Conditions
ConditionsYield
With tetraethoxy orthosilicate; cesium fluoride In neat (no solvent) at 25℃; for 0.166667h;96%
Ethyl propionate
105-37-3

Ethyl propionate

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

Diethyl 2,3-dimethylpentanedioate
344883-66-5

Diethyl 2,3-dimethylpentanedioate

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 1h;96%
C3H7ClMn
105486-13-3

C3H7ClMn

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

ethyl 3,4-dimethylpentanoate
6570-83-8

ethyl 3,4-dimethylpentanoate

Conditions
ConditionsYield
With chloro-trimethyl-silane; copper(l) chloride In tetrahydrofuran 0 to 20 deg C, 0.5-1.5 h; other α,β-ethylenic ester, other organomanganese chlorides;96%
With chloro-trimethyl-silane; copper(l) chloride In tetrahydrofuran 0 to 20 deg C, 0.5-1.5 h;96%
ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

3-azidobutyric acid ethyl ester
189870-35-7

3-azidobutyric acid ethyl ester

Conditions
ConditionsYield
With tris-(2-chloro-ethyl)-amine; triethylamine In benzene at 80℃; for 24h;96%
para-iodoanisole
696-62-8

para-iodoanisole

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

(E)-ethyl 3-(4-methoxyphenyl)but-2-enoate
7706-82-3

(E)-ethyl 3-(4-methoxyphenyl)but-2-enoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 110℃; for 6h; Heck Reaction; Inert atmosphere;96%
With potassium carbonate; triphenylphosphine; palladium diacetate In N,N-dimethyl-formamide for 0.15h; Heck reaction; microwave irradiation;87%
ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

(2S,3R)-ethyl 2,3-dihydroxybutanoate
139165-59-6

(2S,3R)-ethyl 2,3-dihydroxybutanoate

Conditions
ConditionsYield
With methanesulfonamide In water; tert-butyl alcohol at 0 - 24℃; Sharpless dihydroxylation;96%
N-methoxylamine hydrochloride
593-56-6

N-methoxylamine hydrochloride

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

(2E)-N-methoxybut-2-enamide
1569096-25-8

(2E)-N-methoxybut-2-enamide

Conditions
ConditionsYield
Stage #1: N-methoxylamine hydrochloride With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 1h;
Stage #2: ethyl (E)-crotonate In tetrahydrofuran
96%
(2S,3S)-3-benzyloxy-2-(p-methoxybenzyloxymethyl)-3,4-dihydro-2H-pyrrole-1-oxide

(2S,3S)-3-benzyloxy-2-(p-methoxybenzyloxymethyl)-3,4-dihydro-2H-pyrrole-1-oxide

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

ethyl (2R,3S,3aR,5S,6S)-5-(benzyloxy)-6-(p-methoxybenzyloxymethyl)-2-methylhexahydro-pyrrolo[1,2-b]isoxazole-3-carboxylate

ethyl (2R,3S,3aR,5S,6S)-5-(benzyloxy)-6-(p-methoxybenzyloxymethyl)-2-methylhexahydro-pyrrolo[1,2-b]isoxazole-3-carboxylate

Conditions
ConditionsYield
In toluene at 40℃; for 24h; Inert atmosphere;96%
N-(4-bromo-2-nitrophenyl)-N-isobutylspiro[3.3]heptan-2-amine

N-(4-bromo-2-nitrophenyl)-N-isobutylspiro[3.3]heptan-2-amine

ethyl (E)-crotonate
623-70-1

ethyl (E)-crotonate

(E)-ethyl 3-(4-(isobutyl(spiro[3.3]heptan-2-yl)amino)-3-nitrophenyl)but-2-enoate

(E)-ethyl 3-(4-(isobutyl(spiro[3.3]heptan-2-yl)amino)-3-nitrophenyl)but-2-enoate

Conditions
ConditionsYield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium carbonate In N,N-dimethyl-formamide at 110℃; for 4h; Inert atmosphere;96%

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