Ammonium formate supplier | CasNO.540-69-2

Name
Ammonium formate
EINECS 208-753-9
CAS No. 540-69-2
Article Data71
CAS DataBase
Density 1.26 g/cm³
Solubility H₂O: 10 M at 20 °C, clear, colorless
Melting Point 119-121 °C(lit.)
Formula NH₄HCO₂
Boiling Point 100.6oC at 760 mmHg
Molecular Weight 63.0562
Flash Point 29.9oC
Transport Information
Appearance colorless, hygroscopic, crystalline solid
Safety 26-36-37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Ammoniumformate (6CI);Formic acid, ammonium salt (8CI,9CI);
PSA 40.54000
LogP 0.66060

Synthetic route

: 74-90-8
hydrogen cyanide

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With water In hydrogenchloride Kinetics; at 35 45 and 65°C;
With hydrogen bromide In hydrogen bromide Kinetics;
explosive decomposition;

: 5436-21-5
acetylacetaldehyde dimethyl acetal

: 77287-34-4, 77287-35-5, 60100-09-6
formamide

A: 3438-46-8
4-Methylpyrimidine

B: 67-56-1
methanol

C: 540-69-2
ammonium formate

Conditions

Conditions	Yield
at 190℃; for 3.5h;	A 79% B n/a C n/a

...Expand

: 64-18-6
formic acid

: 7664-41-7
ammonia

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
In diethyl ether introduction of dry NH3 into ethereal soln. of HCO2H; recrystallizing from ethanol;
In not given introduction of gaseous NH3 into 90 % HCO2H soln., finishing by higher temperature; recrystallizing from dry alcohol, drying over H2SO4 in vacuum desiccator;
In water neutralization of aq. HCO2H with NH3, evaporation, concentration in vacuo;

ammonium hydrogencarbonate: ammonium hydrogencarbonate

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With water; nickel at 125 - 200℃; under 73550.8 - 330978 Torr; Hydrogenation;

: 201230-82-2
carbon monoxide

: 7664-41-7
ammonia

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With water In gas by higher temperature;
In water
With H2O In neat (no solvent, gas phase) by higher temperature;
In water
With water In gas by higher temperature;

carbon monoxide: carbon monoxide

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With ammonia; water at 160 - 220℃; under 117681 - 279493 Torr;

: 124-38-9
carbon dioxide

: 7664-41-7
ammonia

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
In gas
in present of catalysts;
With H2 In water

: 460-19-5
ethanedinitrile

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With H2O In water further products; in alkaline soln.;
With H2O In water further products; in alkaline soln.;

: 201230-82-2
carbon monoxide

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With nitrogen; water; hydrogen In gas dark electric discharge in a gaseous mixture of N2, H2, H2O, CO and CO2;
With N2; H2; H2O In neat (no solvent, gas phase) dark electric discharge in a gaseous mixture of N2, H2, H2O, CO and CO2;

: H3PO4*HCN

A: 86119-84-8, 7664-38-2
phosphoric acid

B: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With water In water
With H2O In water

: 1066-33-7
ammonium bicarbonate

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With H2; catalyst: (RuCl2(benzene))2/dppm In tetrahydrofuran; water 2 h at 70°C at 50 bar H2; detd. by NMR;

: potassium hexacyanoferrate(III)

A: potassium carbonylpentacyanoferrate(II)

B: 124-38-9
carbon dioxide

C: 540-69-2
ammonium formate

D: 1066-33-7
ammonium bicarbonate

Conditions

Conditions	Yield
With carbon monoxide In water aq. soln. in sealed tube (130°C); excess of CO;;

...Expand

: potassium hexacyanoferrate(III)

A: potassium iron(III) hexacyanoferrate(II)

B: 124-38-9
carbon dioxide

C: 540-69-2
ammonium formate

D: potassium ferrocyanide

Conditions

Conditions	Yield
With carbon monoxide In water aq. soln. in sealed tube (130°C);;

...Expand

: 420-04-2
CYANAMID

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
In water Electrolysis;
In water Electrolysis;

: 124-38-9
carbon dioxide

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With ammonium amalgame
With ammonium amalgame

: 64-18-6
formic acid

: aluminium nitride

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
In water
In water

: 2Fe(2+)*5Fe(3+)*19CN(1-)=2Fe(CN)2*5Fe(CN)3

A: ammonium carbonate

B: 540-69-2
ammonium formate

Conditions

Conditions	Yield
In neat (no solvent) decomposition at 120°C; further byproducts;;
In neat (no solvent) decomposition at 120°C; further byproducts;;

: H3PO4*HCN

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
In water byproducts: H3PO4; hydrolysis;

: HCN*H2SO4

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With air byproducts: H2SO4; hydrolysis;

: 1113-38-8
ammonium oxalate

A: 460-19-5
ethanedinitrile

B: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With glycerol beim Erhitzen; Nebenprod.2:Ammonium-carbonat; Nebenprod.3:Ammonium-cyanid;

: 74-90-8
hydrogen cyanide

: 10035-10-6, 12258-64-9
hydrogen bromide

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
at 45℃; Kinetics; Hydrolysis;

: 124-38-9
carbon dioxide

: 141-53-7
sodium formate

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With ammonia; water

: 124-38-9
carbon dioxide

: 544-17-2
calcium diformate

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
With ammonia

: 124-38-9
carbon dioxide

: 7664-41-7
ammonia

: 141-53-7
sodium formate

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
In not given byproducts: NaHCO3; introduction of NH3 and CO2 into technical sodium formate soln.;

...Expand

: ammonium carbonate monohydrate

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
Electrolysis; electrolysis of a soln. of 800 g (NH4)2CO3 in 3200 cm^3 H2O and 880 cm^3 aq.NH3 (D=0.910) with diaphragm; cathode:zinc; anode:platinum; no reduction with Pb,NI,Fe,Cu,Pt cathode;
Electrolysis; electrolysis of a soln. of 800 g (NH4)2CO3 in 3200 cm^3 H2O and 880 cm^3 aq.NH3 (D=0.910) with diaphragm; cathode:zinc; anode:platinum; no reduction with Pb,NI,Fe,Cu,Pt cathode;

: barium cyanide

: 7732-18-5
water

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
saponification of Ba(CN)2 with water; precipitating of Ba with CO2;
saponification of Ba(CN)2 with water; precipitating of Ba with CO2;

: 75-52-5
nitromethane

A: 540-69-2
ammonium formate

B water: water

Conditions

Conditions	Yield
at 199.9℃; under 13501100 Torr; for 1h; Mechanism; variation of temperature, pressure, time;

: ammonium carbonate

: 544-17-2
calcium diformate

: 540-69-2
ammonium formate

: ammonium nitrate

: 544-17-2
calcium diformate

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
dry distn. at 100°C in vacuo;

: ammonium nitrate

: 141-53-7
sodium formate

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
dry distn. at 100°C in vacuo;

: 93923-85-4
N2-formyl-asparagine

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
bei der Destillation im Vakuum; formyl-l-asparagine;

: 290-87-9
1,3,5-Triazine

: 7732-18-5
water

: 540-69-2
ammonium formate

: 556-64-9
methyl thiocyanate

: ammonium hydroxide

A: 624-92-0
Dimethyldisulphide

B: 540-69-2
ammonium formate

C: 57-13-6
urea

...Expand

: 507-47-1
1-amino-2,2,2-trichloro-ethanol

: 7732-18-5
water

A: 67-66-3
chloroform

B: 540-69-2
ammonium formate

...Expand

: 542-90-5
ethyl isothiocyanate

: ammonium hydroxide

A: 110-81-6
Diethyl disulfide

B: 540-69-2
ammonium formate

C: 57-13-6
urea

...Expand

: 2,2,2-trichloro-4-trichloromethyl-2λ5-[1.3.2]dioxaphosphetane

: 7664-41-7
ammonia

A: 67-66-3
chloroform

B: 540-69-2
ammonium formate

C ammonium phosphate: ammonium phosphate

...Expand

: 141-53-7
sodium formate

ammonium carbonate: ammonium carbonate

: 540-69-2
ammonium formate

Conditions

Conditions	Yield
at 80℃; Destillation im Vakuum bei 100grad;
at 80℃;

: 201230-82-2
carbon monoxide

: 7664-41-7
ammonia

A: ammonium carbonate

B: 540-69-2
ammonium formate

C: 71680-52-9, 130166-69-7
ammonium cyanide

Conditions

Conditions	Yield
High Pressure; 200°C, 170 atm, catalyst: clay;

...Expand

: 852655-84-6
3-(amino-oxazol-2-yl-methyl)-pyrrolidine-1-carboxylic acid benzyl ester

: 540-69-2
ammonium formate

: 852655-85-7
C-oxazol-2-yl-C-pyrrolidin-3-yl-methylamine

Conditions

Conditions	Yield
palladium 10% on activated carbon In methanol at 65℃; for 2.5h;	100%

: 540-69-2
ammonium formate

: 115419-53-9
C15H15ClN2

: 115419-56-2
C16H16N2O2

Conditions

Conditions	Yield
In methanol for 1h; Ambient temperature;	98%

: 540-69-2
ammonium formate

: 100039-05-2
N,N'-Bis-'D'-5-aminopyrrolidin-2-one

: 100039-06-3, 100039-08-5
'D'-5-Aminopyrrolidin-2-one Formic Acid Salt

Conditions

Conditions	Yield
With hydrogen; palladium In methanol; N,N-dimethyl-formamide for 0.166667h;	97%

: 540-69-2
ammonium formate

: 66488-70-8
N,N'-Bis-'L'-5-aminopyrrolidin-2-one

: 100039-06-3
'L'-5-Aminopyrrolidin-2-one formic acid salt

Conditions

Conditions	Yield
With hydrogen; palladium In methanol; N,N-dimethyl-formamide for 0.166667h;	95%

: 16940-66-2
sodium tetrahydroborate

: 540-69-2
ammonium formate

: 10043-11-5
ammonia borane complex

Conditions

Conditions	Yield
In 1,4-dioxane byproducts: H2, NaO2CH; (inert atmosphere); dioxane added to NaBH4 and NH4O2CH, stirred vigorously at 40°C for ca 2 h; cooled to room temp., filtered, washed (dioxane); the combined filtratesconcd. (vac.); elem. anal.;	95%
In tetrahydrofuran (inert atmosphere); at 25-40°C for 2-25 h;	93%
In tetrachloromethane (inert atmosphere); at 40°C for 13 h;

: 540-69-2
ammonium formate

: Z-MePhe-MeA2bu(γPht)-O-tBu

: MePhe-MeA2bu(γPht)-O-tBu*HCOOH

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In methanol for 1h; Ambient temperature;	92%

: 540-69-2
ammonium formate

: 108-94-1
cyclohexanone

: 134420-07-8
cycloheptyl isonitrile

: 134455-15-5
1-Formylamino-cyclohexanecarboxylic acid cycloheptylamide

Conditions

Conditions	Yield
In methanol; water for 1h; Heating;	92%

...Expand

: 1072-72-6
Tetrahydrothiopyran-4-one

: 540-69-2
ammonium formate

: 134420-07-8
cycloheptyl isonitrile

: 156490-26-5
N-cycloheptyl-4-formylaminotetrahydrothiopyran-4-carboxamide

Conditions

Conditions	Yield
In methanol; water for 1h; Heating;	90%

...Expand

: 540-69-2
ammonium formate

: 92261-85-3
PhOCH2CO-Arg(NO2)-Ala-OBzl

: PhO-CH2CO-Arg-Ala*HCOOH

Conditions

Conditions	Yield
palladium In methanol; formic acid Ambient temperature;	90%

: cobalt(II) chloride hexahydrate

: 540-69-2
ammonium formate

: [ammonium][Co(II)(formate)3]

Conditions

Conditions	Yield
In methanol MeOH soln. of (NH4)(HCOO) was placed at the bottom of a glass tube and at this soln. MeOH was gently added followed by layering MeOH soln. of Co-contg. compd.; the tube was sealed and kept undisturbed; crystals were harvested after 5 d; crystals were washed with methanol and dried under vac.; elem. anal.;	90%

: 540-69-2
ammonium formate

: 80235-72-9
1-(3,4-dimethoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethan-1-one

: 80235-74-1
N-(1-(3,4-dimethoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethyl)formamide

Conditions

Conditions	Yield
With formic acid; formamide at 185 - 190℃; for 3.5h;	88%

: 540-69-2
ammonium formate

: 148183-79-3
3-(2-phenyl-5-trifluoromethyloxazol-4-yl)propanol

: Formic acid 3-(2-phenyl-5-trifluoromethyl-oxazol-4-yl)-propyl ester

Conditions

Conditions	Yield
In xylene for 37h; Heating;	86%

: 540-69-2
ammonium formate

: 92261-86-4
PhO-CH2CO-D-Arg(NO2)-D-Ala-OBzl

: PhO-CH2CO-D-Arg-D-Ala*HCOOH

Conditions

Conditions	Yield
palladium In methanol; formic acid Ambient temperature;	85%

: 10349-38-9
p-methoxyphenylisocyanide

: 540-69-2
ammonium formate

: 108-94-1
cyclohexanone

: 134455-14-4
1-Formylamino-cyclohexanecarboxylic acid (4-methoxy-phenyl)-amide

Conditions

Conditions	Yield
In methanol; water for 0.5h; Heating;	85%

...Expand

: ammonium oxopentachloromolybdate

: 540-69-2
ammonium formate

: triammonium μ-formato-(O,O')-di-μ-oxo-bis(diformato(oxo)molybdate(V))

Conditions

Conditions	Yield
In ethanol Mo-compound dissolved in ammonium formate soln., mixed with ethanol, set aside for 1 day;; washed with ethanol, reprecipitated, elem. anal.;	85%

: 540-69-2
ammonium formate

: 34946-82-2
copper(II) bis(trifluoromethanesulfonate)

: 156-87-6
propan-1-ol-3-amine

: (3-aminopropanolato)formatocopper(II)

Conditions

Conditions	Yield
With C2H5OH In ethanol to soln. of Cu(CF3COO)2 in EtOH was added a soln. of NH2(CH2)3OH in EtOH and a soln. of HCOONH4 in EtOH, kept at room temp. for 1 d; ppt. filtered, washed with EtOH, acetone;	85%

...Expand

: 540-69-2
ammonium formate

: 115419-52-8
N-phenylpropionohydrazonoyl chloride

: 115419-55-1
1-formyl-1-phenyl-2-propionylhydrazine

Conditions

Conditions	Yield
In methanol for 0.25h; Ambient temperature;	84%

: 540-69-2
ammonium formate

: 115419-54-0
C14H21ClN2

: 115419-58-4
N’-formyl-N’-phenyl-n-caprylhydrazide

Conditions

Conditions	Yield
In methanol for 2h; Ambient temperature;	84%

: 931-53-3
Cyclohexyl isocyanide

: 540-69-2
ammonium formate

: 108-94-1
cyclohexanone

: 4507-61-3
1-Formylamino-cyclohexan-

Conditions

Conditions	Yield
In methanol; water for 0.5h; Heating;	84%

...Expand

: 931-53-3
Cyclohexyl isocyanide

: 540-69-2
ammonium formate

: 66-99-9
β-naphthaldehyde

: 128243-50-5
N-Cyclohexyl-2-formylamino-2-naphthalen-2-yl-acetamide

Conditions

Conditions	Yield
In methanol for 0.5h; Heating;	82%

...Expand

: 88333-03-3, 10340-91-7
Benzyl isocyanide

: 540-69-2
ammonium formate

: 120-92-3
cyclopentanone

: 134420-09-0
N-benzyl-1-formamidocyclopentane-1-carboxamide

Conditions

Conditions	Yield
In methanol; water for 1.5h; Heating;	82%

...Expand

: 931-53-3
Cyclohexyl isocyanide

: 540-69-2
ammonium formate

: 589-92-4
1-methylcyclohexan-4-one

: 148751-15-9
1-Formylamino-4-methyl-cyclohexanecarboxylic acid cyclohexylamide

Conditions

Conditions	Yield
In methanol; water for 1h; Heating;	81%

...Expand

Ammonium formate Consensus Reports

Reported in EPA TSCA Inventory.

Ammonium formate Specification

The Ammonium formate, also known as Formic acid, ammonium salt, is an organic compound with the formula NH₄HCO₂. It belongs to the product categories of Industrial/Fine Chemicals; Alphabetical Synthetic Reagents; Ammonium Biological Buffers; Biological Buffers; BioUltra Buffers; Buffer Solutions Protein Structural Analysis; Inorganic Salts; Optimization Reagents; X-Ray Crystallography. Its EINECS registry number is 208-753-9. With the CAS registry number 540-69-2, its IUPAC name is azanium formate. It is a colorless, hygroscopic, crystalline solid.

Physical properties of Ammonium formate: (1)H-Bond Donor: 1; (2)H-Bond Acceptor: 2; (3)Rotatable Bond Count: 0; (4)Exact Mass: 63.032028; (5)MonoIsotopic Mass: 63.032028; (6)Topological Polar Surface Area: 41.1; (7)Heavy Atom Count: 4; (8)Formal Charge: 0; (9)Complexity: 7.5; (10)Isotope Atom Count: 0; (11)Defined Atom StereoCenter Count: 0; (12)Undefined Atom StereoCenter Count: 0; (13)Defined Bond StereoCenter Count: 0; (14)Undefined Bond StereoCenter Count: 0; (15)Covalently-Bonded Unit Count: 2.

Preparation of Ammonium formate: this chemical can be prepared by formic acid and NH₃ via neutralization reaction. The formic acid and H₂O is freezed. The reaction mixture is stirred at -5 °C with the PH value of 7-7.5 and is filtered. Finally, you can get Ammonium formate.

Uses: formic acid can be obtained by reacting Ammonium formate with a dilute acid, and since ammonium formate is also produced from formic acid, it can serve as a way of storing formic acid. Ammonium formate can also be used in palladium on carbon (Pd/C) reduction of functional groups. Ammonium formate can be used for reductive amination of aldehydes and ketones. Ammonium formate can be used as a buffer in high performance liquid chromatography (HPLC), and is suitable for use with liquid chromatography/mass spectroscopy (LC/MS).

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C(=O)[O-].[NH4+]
(2)InChI: InChI=1S/CH2O2.H3N/c2-1-3;/h1H,(H,2,3);1H3
(3)InChIKey: VZTDIZULWFCMLS-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	410mg/kg (410mg/kg)		Zeitschrift fuer Ernaehrungswissenschaft. Vol. 9, Pg. 332, 1969.
mouse	LD50	oral	2250mg/kg (2250mg/kg)		Zeitschrift fuer Ernaehrungswissenschaft. Vol. 9, Pg. 332, 1969.

Product Name

Ammonium formate

Synthetic route

Ammonium formate Consensus Reports

Ammonium formate Specification

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