TRIMETHOXYBOROXINE supplier

Name
Trimethoxyboroxine
EINECS 203-016-8
CAS No. 102-24-9
Article Data44
CAS DataBase
Density 1.216
Solubility reacts
Melting Point 10 °C(lit.)
Formula C3H9 B3 O6
Boiling Point 130 °C(lit.)
Molecular Weight 173.534
Flash Point 14 ºC
Transport Information UN 2924
Appearance colorless not quite clear liquid
Safety Slightly toxic by ingestion. When heated to decomposition it emits toxic fumes of boron.
Risk Codes R11;R38;R41
Molecular Structure
Hazard Symbols
Synonyms Boroxin,trimethoxy- (6CI,7CI,8CI,9CI); Boric acid (H3B3O6), trimethyl ester; NSC 56370;TMBX; Trimethoxyboroxin; Trimethoxyboroxine
PSA 55.38000
LogP -1.05630

Synthetic route

: 124-38-9
carbon dioxide

: 0.95C4H11BO*0.05Na(1+)*0.05BH4(1-)

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 12h; Schlenk technique; Inert atmosphere;	87%

: 14044-65-6
borane-THF

: 124-38-9
carbon dioxide

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
With sodium tetrahydroborate In tetrahydrofuran for 12h; Reagent/catalyst; Schlenk technique; Inert atmosphere;	83%

: 13292-87-0
dimethylsulfide borane complex

: 1111-72-4
carbon dioxide

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
With C27H53BN2P2 at 60℃; under 3800.26 Torr; for 11h; Reagent/catalyst; Inert atmosphere;	80%

: 124-38-9
carbon dioxide

: 13292-87-0
dimethylsulfide borane complex

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
With C39H45N2(1+)CHO2(1-)BH3O3 In benzene-d6 at 20℃; under 760.051 Torr; for 6h;	67%
With C24H18BO2P at 70℃; under 760.051 Torr; for 1h; Catalytic behavior; Reagent/catalyst; Inert atmosphere;
With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In benzene-d6 at 80℃; under 760.051 Torr; for 21h; Catalytic behavior; Reagent/catalyst; Temperature; Time; Solvent; Sealed tube;	> 99 %Spectr.

: 121-43-7
Trimethyl borate

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
With boron trioxide
With boric acid

: 868-81-5
chlorodimethoxyborane

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
at 250℃;
at 250℃;
250°C, 10 h, in sealed tube;
In neat (no solvent) decompn. on heating or by Lewis-acid catalysis;;

: 121-43-7
Trimethyl borate

B2O3: B2O3

: 102-24-9
cyclotriboric acid trimethyl ester

: 121-43-7
Trimethyl borate

boroxide: boroxide

: 102-24-9
cyclotriboric acid trimethyl ester

: boron trioxide

: 121-43-7
Trimethyl borate

: 102-24-9
cyclotriboric acid trimethyl ester

: 121-43-7
Trimethyl borate

: 7732-18-5
water

A: 67-56-1
methanol

B: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
In methanol controlled partial hydrolysis; addn. of 2-methyl pentane, removal of CH3OH/2-methyl pentane azeotrope by distn.;;

...Expand

: 64-18-6
formic acid

: 19287-45-7
diborane

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
In tetrahydrofuran byproducts: H2; reduction at 0°C;;
In tetrahydrofuran byproducts: H2; reduction at 0°C;;

: 64-18-6
formic acid

: 13283-31-3
borane

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
In tetrahydrofuran byproducts: H2; reduction at 0°C;;

: 67-56-1
methanol

: boron trioxide

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
In neat (no solvent) byproducts: H3BO3; generation of B(OCH3)3 from CH3OH and B2O3, filtration of H3BO3, addn. of B2O3;;
In neat (no solvent) byproducts: H2O; separation of H2O as azeotrope with CCl4;;
In neat (no solvent) byproducts: H3BO3; generation of B(OCH3)3 from CH3OH and B2O3, filtration of H3BO3, addn. of B2O3;;

: 121-43-7
Trimethyl borate

: 7732-18-5
water

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
In hexane byproducts: CH3OH; hydroylsis in hexane, azeotropic distn. of hexane/CH3OH-mixture;;
In neat (no solvent) partial hydroysis of 114ml B(OCH3)3 with 17ml H2O by refluxing, addn. of 2.4-dimethyl butane, distn. of dimethyl butane/CH3OH azeotrope after 6h;;
In hexane byproducts: CH3OH; hydroylsis in hexane, azeotropic distn. of hexane/CH3OH-mixture;;

: 67-56-1
methanol

: 121-43-7
Trimethyl borate

: 11113-50-1
boric acid

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
In neat (no solvent) 3mol B(OCH3)3, 3mol methanol, 6mol H3BO3; heating;;

...Expand

: 67-56-1
methanol

: 121-43-7
Trimethyl borate

: 11113-50-1
boric acid

A: 13460-51-0
metaboric acid

B: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
In methanol byproducts: H2O; at 100°C, filtration of metaboric acid;;

...Expand

: 10294-33-4
boron tribromide

: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
In neat (no solvent) byproducts: CH3Br;
In neat (no solvent) byproducts: CH3Br;

: 124-38-9
carbon dioxide

: 13292-87-0
dimethylsulfide borane complex

A: 121-43-7
Trimethyl borate

B: 102-24-9
cyclotriboric acid trimethyl ester

Conditions

Conditions	Yield
With C43H44BClN2P2 In benzene-d6 at 80℃; under 750.075 Torr; for 2h; Catalytic behavior; Reagent/catalyst;	A 8 %Spectr. B 91 %Spectr.
With C29H35B2LiOP2S2 In tetrahydrofuran at 80℃; under 750.075 Torr; for 4h; Catalytic behavior; Reagent/catalyst; Time; Temperature; Schlenk technique;
With diisopropyl-carbodiimide In benzene-d6 at 25℃; under 760.051 Torr; for 24h; Catalytic behavior; Reagent/catalyst; Temperature; Glovebox; Inert atmosphere; Schlenk technique;

...Expand

: 102-24-9
cyclotriboric acid trimethyl ester

: 7782-50-5
chlorine

A: boron trioxide

B: 10294-34-5
boron trichloride

Conditions

Conditions	Yield
byproducts: HCl, ClCOCl; at room temp.;;	A n/a B 96%

...Expand

: 102-24-9
cyclotriboric acid trimethyl ester

: 178876-83-0
methyl 6-amino-3-bromo-pyridine-2-carboxylate

: 1319069-28-7
6-amino-3-methyl-pyridine-2-carboxylic acid methyl ester

Conditions

Conditions	Yield
With potassium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In 1,4-dioxane at 115℃; for 4h; Inert atmosphere;	88%

: 102-24-9
cyclotriboric acid trimethyl ester

: 1145663-94-0, 1146220-12-3
[(2,6-(Me2NCH2)2C6H3)SbO]2

: C14H25B2N2O5Sb

Conditions

Conditions	Yield
In benzene at 20℃; for 12h;	82%

: 102-24-9
cyclotriboric acid trimethyl ester

: 33295-35-1
2-bromo-8-methylnaphthalene

: 1454286-46-4
8-methylnaphthalene-2-boronic acid

Conditions

Conditions	Yield
Stage #1: 2-bromo-8-methylnaphthalene With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h; Stage #2: cyclotriboric acid trimethyl ester In tetrahydrofuran; hexane at -78 - 20℃; for 3.5h;	77%

: 102-24-9
cyclotriboric acid trimethyl ester

: 495-18-1
Benzohydroxamic acid

: (C6H5CONHO)B(OH)2

Conditions

Conditions	Yield
In ethanol; water byproducts: CH3OH; added 80% aq. ethanol to a mixture of compounds; refluxed for 6 h; solvent evapd.; recrystd. from 80% aq. ethanol; elem. anal.;	75%

: 102-24-9
cyclotriboric acid trimethyl ester

: 17512-69-5
2-chlorophenylhydroxamic acid

: (2-ClC6H4CONHO)B(OH)2

Conditions

Conditions	Yield
In ethanol; water byproducts: CH3OH; added 80% aq. ethanol to a mixture of compounds; refluxed for 6 h; solvent evapd.; recrystd. from 80% aq. ethanol; elem. anal.;	73%

: 121-43-7
Trimethyl borate

: 102-24-9
cyclotriboric acid trimethyl ester

A: 67-56-1
methanol

B: 11113-50-1
boric acid

Conditions

Conditions	Yield
With water	A 72.5% B n/a

...Expand

: 102-24-9
cyclotriboric acid trimethyl ester

: 1613-76-9
4-nitrobenzohydroxamic acid

: (4-NO2C6H4CONHO)B(OH)2

Conditions

Conditions	Yield
In ethanol; water byproducts: CH3OH; added 80% aq. ethanol to a mixture of compounds; refluxed for 6 h; solvent evapd.; recrystd. from 80% aq. ethanol; elem. anal.;	72%

: 102-24-9
cyclotriboric acid trimethyl ester

: 1528-82-1
N-(4-chlorophenyl)benzohydroxamic acid

: (C6H5CON(4-ClC6H4)O)B(OH)2

Conditions

Conditions	Yield
In ethanol; water byproducts: CH3OH; added 80% aq. ethanol to a mixture of compounds; refluxed for 6 h; solvent evapd.; recrystd. from 80% aq. ethanol; elem. anal.;	70%

: 102-24-9
cyclotriboric acid trimethyl ester

: 10507-69-4
4-methoxybenzohydroxamic acid

: (4-MeOC6H4CONHO)B(OH)2

Conditions

Conditions	Yield
In ethanol; water byproducts: CH3OH; added 80% aq. ethanol to a mixture of compounds; refluxed for 6 h; solvent evapd.; recrystd. from 80% aq. ethanol; elem. anal.;	70%

: 102-24-9
cyclotriboric acid trimethyl ester

: 1356930-95-4
(2,6-(Me2NCH2)2C6H3)(Ph)SnCO3

: C20H30B2N2O5Sn

Conditions

Conditions	Yield
at 20℃; for 12h;	70%

: 102-24-9
cyclotriboric acid trimethyl ester

: 1503-92-0
N-p-tolylbenzohydroxamic acid

: (C6H5CON(4-MeC6H4)O)B(OH)2

Conditions

Conditions	Yield
In ethanol; water byproducts: CH3OH; added 80% aq. ethanol to a mixture of compounds; refluxed for 6 h; solvent evapd.; recrystd. from 80% aq. ethanol; elem. anal.;	68%

: 102-24-9
cyclotriboric acid trimethyl ester

: 1613-88-3
4-chloro-N-hydroxybenzamide

: (4-ClC6H4CONHO)B(OH)2

Conditions

Conditions	Yield
In ethanol; water byproducts: CH3OH; added 80% aq. ethanol to a mixture of compounds; refluxed for 6 h; solvent evapd.; recrystd. from 80% aq. ethanol; elem. anal.;	68%

: 1116-39-8
triisobutylborane

: 102-24-9
cyclotriboric acid trimethyl ester

: 7439-47-6
Triisobutyl-boroxin

Conditions

Conditions	Yield
In neat (no solvent) byproducts: B(OCH3)3; heating equimolar amounts of educts (131-207°C), removal of generated B(OCH3)3 by distn. in the course of the react.;; 2fold distn.;;	64%

: 102-24-9
cyclotriboric acid trimethyl ester

: 100-58-3
phenylmagnesium bromide

A: 67-56-1
methanol

B: 2622-89-1
diphenylborinic acid

Conditions

Conditions	Yield
With water byproducts: BrMgOH;	A n/a B 62%
With H2O byproducts: BrMgOH;	A n/a B 62%

...Expand

: 102-24-9
cyclotriboric acid trimethyl ester

: 703-55-9
1-naphthylmagnesiumbromide

A: 67-56-1
methanol

B: 62981-91-3
bis(1-naphthyl)borinic acid

Conditions

Conditions	Yield
With water byproducts: BrMgOH;	A n/a B 62%
With H2O byproducts: BrMgOH;	A n/a B 62%

...Expand

: 102-24-9
cyclotriboric acid trimethyl ester

: 17512-68-4
2-nitrobenzohydroxamic acid

: (2-NO2C6H4CONHO)B(OH)2

Conditions

Conditions	Yield
In ethanol; water byproducts: CH3OH; added 80% aq. ethanol to a mixture of compounds; refluxed for 6 h; solvent evapd.; recrystd. from 80% aq. ethanol; elem. anal.;	61%

: 102-24-9
cyclotriboric acid trimethyl ester

: 304-88-1
N-phenylbenzohydroxamic acid

: (C6H5CON(C6H5)O)B(OH)2

Conditions

Conditions	Yield
In ethanol; water byproducts: CH3OH; added 80% aq. ethanol to a mixture of compounds; refluxed for 6 h; solvent evapd.; recrystd. from 80% aq. ethanol; elem. anal.;	60%

: 102-24-9
cyclotriboric acid trimethyl ester

: 1143-74-4
N-o-tolylbenzohydroxamic acid

: (C6H5CON(2-MeC6H4)O)B(OH)2

Conditions

Conditions	Yield
In ethanol; water byproducts: CH3OH; added 80% aq. ethanol to a mixture of compounds; refluxed for 6 h; solvent evapd.; recrystd. from 80% aq. ethanol; elem. anal.;	60%

: [Ni(Heptox.H)2]

: 102-24-9
cyclotriboric acid trimethyl ester

: Mono(dimethoxyboroxino)-bis(1,2-cycloheptandiondioximato)nickel(II)

Conditions

Conditions	Yield
In benzene byproducts: methanol; addn. of boroxine soln. in benzene to the hot soln. of Ni-chelate in benzene, 30 min boiling; concn., filtration, recrystn. from benzene, elem. anal.;	49%

: 1113-78-6
tri(sec-butyl)borane

: 102-24-9
cyclotriboric acid trimethyl ester

A: 7359-98-0
tri-n-butylboroxine

B: 7555-37-5
{B(s-C4H9)O}3

Conditions

Conditions	Yield
In neat (no solvent) byproducts: B(OCH3)3; heating equimolar amounts of educts (149-197°C) for 1h, removal of generated B(OCH3)3 in the course of react.;; isomeric mixture after distn. in vac. (isomerization); pure (B(s-C4H9)O)3 after redistn. of the first fraction;;	A n/a B 35%

...Expand

: 102-24-9
cyclotriboric acid trimethyl ester

: 873-77-8
(4-chlorphenyl)magnesium bromide

A: 67-56-1
methanol

B: 89566-59-6
di-(p-chlorophenyl)borinic acid

Conditions

Conditions	Yield
With water byproducts: BrMgOH;	A n/a B 22%
With H2O byproducts: BrMgOH;	A n/a B 22%

...Expand

: 102-24-9
cyclotriboric acid trimethyl ester

: 917-54-4
methyllithium

A: 593-90-8
trimethylborane

B: 4443-43-0
methoxy-dimethyl-borane

C: 7318-81-2
bis(methoxy)methylborane

Conditions

Conditions	Yield
With hydrogenchloride In diethyl ether under N2; to cold (-78 °C) soln. of boron compd. in Et2O slowly added MeLi, stirred for 0.5 h, warmed to room temp., stirred for 0.5 h,Li(BMe4) detected by (11)B NMR, cooled to 0 °C, added soln. of HCl in Et2O, stirred for 15 min, warmed; not isolated, monitored by (11)B NMR;	A 20% B <1 C <1

...Expand

: 932-31-0
ortho-tolylmagnesium bromide

: 102-24-9
cyclotriboric acid trimethyl ester

: 73774-44-4
bis(2-methylphenyl)borinic acid

Conditions

Conditions	Yield
Isolierung als 2-o-tolyl-boryloxy>-aethylamin;

: 102-24-9
cyclotriboric acid trimethyl ester

: 557-20-0
diethylzinc

: 97-94-9
triethyl borane

TRIMETHOXYBOROXINE Chemical Properties

The formula of TRIMETHOXYBOROXINE(102-24-9 ) is C₃H₉B₃O₆.
There are some TRIMETHOXYBOROXINE(102-24-9 )'s descriptions:
Mol weight: 173.53
Physical properties:Colorless liquid, flammable, sensitive to moisture.
Boiling point: 130 °C.
Density: 1.195 g/cm³ (25 °C).
Melting point: 10 °C.
Vapour pressure: 30 mm Hg (25 °C).
Specification: Appearance colorless not quite clear liquid
Purity 96 % min

TRIMETHOXYBOROXINE Toxicity Data With Reference

orl-rat LD50:5160 mg/kg

14KTAK Boron, Metallo-Boron Compounds and Boranes R.M. Adams,New York, NY.: Wiley,1964,693.

TRIMETHOXYBOROXINE Consensus Reports

Reported in EPA TSCA Inventory.

TRIMETHOXYBOROXINE Safety Profile

Slightly toxic by ingestion. When heated to decomposition TRIMETHOXYBOROXINE(102-24-9 ) emits toxic fumes of boron.

Product Name

Trimethoxyboroxine

Synthetic route

TRIMETHOXYBOROXINE Chemical Properties

TRIMETHOXYBOROXINE Toxicity Data With Reference

TRIMETHOXYBOROXINE Consensus Reports

TRIMETHOXYBOROXINE Safety Profile

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