Trifluoroacetic anhydride supplier

Name
Trifluoroacetic anhydride
EINECS 206-982-9
CAS No. 407-25-0
Article Data75
CAS DataBase
Density 1.641 g/cm³
Solubility hydrolysis with water
Melting Point -63.5 °C
Formula C₄F₆O₃
Boiling Point 39.5 °C at 760 mmHg
Molecular Weight 210.033
Flash Point -26 °C
Transport Information UN 3265 8/PG 1
Appearance Clear, colorless liquid
Safety 26-36/37/39-43-45-61-9-8-28A-27
Risk Codes 14-20-35-52/53-34-23/24/25
Molecular Structure
Hazard Symbols C, T
Synonyms Aceticacid, trifluoro-, anhydride (6CI,8CI,9CI);2,2,2-Trifluoroacetic anhydride;Bis(trifluoroacetic) anhydride;Hexafluoroacetic anhydride;NSC 96965;Perfluoroacetic anhydride;Trifluoroacetic acid anhydride;Trifluoroacetyl anhydride;Trifluoroacetic anhydride(TFAA);
PSA 43.37000
LogP 1.18080

Synthetic route

: 64899-09-8
N-(n-butyl)-2,4-dinitrotrifluoroacetanilide

A: 13059-86-4
2,4-dinitro-N-butylaniline

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
With tris buffers; cetyltrimethylammonim bromide at 25℃; Rate constant; hydrolysis, other quaterner amines;	A 99.7% B n/a

: 76-05-1
trifluoroacetic acid

: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
With fuming sulphuric acid at 130℃; Large scale;	99%
With fuming sulphuric acid at 78 - 130℃; Large scale;	99%
With sulfuric acid; sulfur trioxide at 130℃;	99%

: 421-59-0
trifluoromethyldiiodophosphine

: 2966-50-9
silver trifluoroacetate

A: 1682-76-4
Trifluormethylphosphonigsaeure-bis(trifluoressigsaeure)anhydrid

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
within 10 h;	A n/a B 98%
10 min; isolation from volatile part of product;	A n/a B 72%

...Expand

: 1493-13-6
trifluorormethanesulfonic acid

: 76-05-1
trifluoroacetic acid

A: 407-25-0
trifluoroacetic anhydride

B: 68602-57-3
trifluoroacetyl triflate

Conditions

Conditions	Yield
With phosphorus pentoxide at -20 - 240℃; for 3.5h;	A n/a B 75%

...Expand

: 86024-51-3
Cl2SNTeF5

: 2966-50-9
silver trifluoroacetate

A: 86024-52-4
F5TeNSO

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
In neat (no solvent) Cl2S=NTeF5 and CF3COOAg stirred at room temp. and warmed to 45°Cand stirred for 1 h; O=S=NTeF5 and (CF3CO)2O condensed into -196°C trap under vac., separation achieved by trap-to-trap distillation through -45 (O=S=NTeF5) and -78°C cooled traps; elem. anal.;	A 68% B n/a

...Expand

: 407-38-5
2,2,2-trifluoroethyl trifluoroacetate

A: 353-50-4
Carbonyl fluoride

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
With chlorine at 22.84℃; under 760 Torr; Irradiation; Synthetic gas;	A 35% B 45%

: 13257-51-7
mercury(II) trifluoroacetate

: 2757-23-5
chloro(chlorosulfanyl)methanone

: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
at 50 - 55℃; for 3h;	30%

: 650-09-9
O,O-Diethyl O-Trifluoroacetyl Phosphate

A: 107-49-3
Tetraethyl pyrophosphate

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
Erhitzen im Vakuum;

: 350-70-9
tris(trifluoro acetyloxy)borane

A: 330-25-6
tetrakis-trifluoroacetoxy-diboroxane

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
at 100℃; under 0.0001 Torr;
at 100℃; under 0.0001 Torr;

: 2966-50-9
silver trifluoroacetate

: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
With phosphorus at 180℃;
With sulfur at 300℃;

: 60884-90-4
calcium bistrifluoroacetate

A: 354-34-7
trifluoroacetyl fluoride

B: 407-25-0
trifluoroacetic anhydride

: 76-05-1
trifluoroacetic acid

A: 354-34-7
trifluoroacetyl fluoride

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
Erhitzen des Lithium-Salzes;

: 2377-97-1
Bis(trifluormethyl)phosphinigsaeure-trifluoressigsaeureanhydrid

A: 2728-67-8
Tetrakis(trifluormethyl)disphosphoxan

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
at 40℃; Equilibrium constant;
within 24 h;
equil.;

: 19480-01-4
trifluoromethyl isocyanide

: 76-05-1
trifluoroacetic acid

A: 109975-95-3
N-(trifluoromethyl)formamide

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
Ambient temperature; Yield given. Yields of byproduct given;

...Expand

: 76-05-1
trifluoroacetic acid

: 68602-57-3
trifluoroacetyl triflate

A: 1493-13-6
trifluorormethanesulfonic acid

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
Equilibrium constant;

...Expand

: 72925-88-3
N-Allyl-9-anthracenemethanimine

A: 72917-92-1, 72917-93-2, 344598-97-6
2-(Trifluoroacetyl)-1,2,3,3a,4,5-hexahydro-5,9b-o-benzenobenzisoindol-1-ol

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
In dichloromethane for 24h; Ambient temperature; Title compound not separated from byproducts;

: 26525-13-3
3,6-dehydrohomoadamantane

: 27184-84-5
chromyl trifluoroacetate

A: 407-25-0
trifluoroacetic anhydride

B: 3-oxobicyclo[3.3.1]nonane-7-spirocyclopropane

C: Trifluoro-acetic acid 6-hydroxy-tricyclo[4.3.1.13,8]undec-3-yl ester

Conditions

Conditions	Yield
In tetrachloromethane at 0℃; for 0.5h;	A 17 % Spectr. B 34 % Spectr. C 42 % Spectr.

...Expand

: 129880-36-0
Caesium; 2,3,3,3-tetrafluoro-2-methoxy-propionate

A: 353-50-4
Carbonyl fluoride

B: 354-34-7
trifluoroacetyl fluoride

C: 3823-94-7
methyl 1,2,2-trifluorovinyl ether

D: 10186-63-7
2-fluoro-2-methoxy trifluoropropanoic acid methyl ester

E: 85036-47-1
α-methoxytetrafluoropropionyl fluoride

F: 407-25-0
trifluoroacetic anhydride

G CsF, CO2, CH3F: CsF, CO2, CH3F

Conditions

Conditions	Yield
at 250℃; under 0.01 Torr; for 1.5h; Product distribution; Mechanism;

...Expand

: 7553-56-2
iodine

: 2966-50-9
silver trifluoroacetate

: 71-43-2
benzene

A: 591-50-4
iodobenzene

B: 407-25-0
trifluoroacetic anhydride

...Expand

: 359-64-8
iodo-bis-trifluoromethyl-phosphine

: 2966-50-9
silver trifluoroacetate

A: 2377-97-1
Bis(trifluormethyl)phosphinigsaeure-trifluoressigsaeureanhydrid

B: 2728-67-8
Tetrakis(trifluormethyl)disphosphoxan

C: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
byproducts: AgI; below 20°C; further react. in equil.; distn.; main product as medium fraction at 0°C / 55 Torr;

...Expand

: 1682-76-4
Trifluormethylphosphonigsaeure-bis(trifluoressigsaeure)anhydrid

A: 2728-67-8
Tetrakis(trifluormethyl)disphosphoxan

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
18.5 degree.C; equil.; value for equil. const. given at 40°C;

: 1682-76-4
Trifluormethylphosphonigsaeure-bis(trifluoressigsaeure)anhydrid

: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
With (CH3)3N formation from unidentified intermediate product;

: yttrium trifluoroacetate

A: 13709-49-4
yttrium(III) fluoride

B: 124-38-9
carbon dioxide

C: 201230-82-2
carbon monoxide

D: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
With O2 or Ar In neat (no solvent) decompn. at 300 ° C in Ar and at 230-270 ° C in O2; YF3 formed;

...Expand

: (trifluoro methyl) tris-(trifluoro acetoxy) germane

A: 124-38-9
carbon dioxide

B: germanium dioxide

C: 7783-61-1
silicon tetrafluoride

D: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
In neat (no solvent) pyrolysis at 240°C within 24 hours;;

...Expand

: 383-63-1
ethyl trifluoroacetate,

: 302-01-2
hydrazine

A: 667-35-6
1,2-bis(trifluoroacetyl)hydrazine

B: 76-05-1
trifluoroacetic acid

C: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
In ethanol dropping of soln. of CF3COOC2H5 in abs. alc. to N2H4 soln. in anhydrous C2H5OH by cooling, stirring at 20°C (12 h); evapn. of C2H5OH, stirring at 20°C (12 h);

...Expand

: 67756-31-4
S-trifluoromethylcarbonothioic trifluoroacetic anhydride

: 51615-93-1
S,S'-Bis(trifluormethyl)dithiocarbonat

B: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
Irradiation (UV/VIS); photolysis;
Irradiation (UV/VIS); photolysis;

: 60669-28-5
Trifluoromethyliodine(III) bis-trifluoroacetate

A: 2314-97-8
iodotrifluoromethane

B: 56407-84-2
trifluoromethyliodine dioxide

C: 407-25-0
trifluoroacetic anhydride

Conditions

Conditions	Yield
above -6°C;

...Expand

: 109-97-7
pyrrole

: 407-25-0
trifluoroacetic anhydride

: 2557-70-2
2-(trifluoroacetyl)pyrrole

Conditions

Conditions	Yield
	100%
With benzene
With 1H-imidazole

: 106-47-8
4-chloro-aniline

: 407-25-0
trifluoroacetic anhydride

: 404-25-1
N-(4-chlorophenyl)-2,2,2-trifluoroacetamide

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 0 - 20℃; for 0.75h;	100%
With triethylamine In dichloromethane at 0 - 20℃; for 2h;	88%
In diethyl ether for 1h; Ambient temperature;	84%

: 104-94-9
4-methoxy-aniline

: 407-25-0
trifluoroacetic anhydride

: 332-34-3
2,2,2-trifluoro-N-(4-methoxy-phenyl)-acetamide

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 20℃;	100%
With triethylamine In tetrahydrofuran at 0 - 20℃; for 0.75h;	100%
at 20℃; for 1h;	98.3%

: 75-31-0
isopropylamine

: 407-25-0
trifluoroacetic anhydride

: 348-76-5
2,2,2-trifluoro-N-(1-methylethyl)acetamide

Conditions

Conditions	Yield
With pyridine; dmap In tetrahydrofuran at 20℃; for 15h;	100%
With diethyl ether
In diethyl ether
at 0℃; than Rt, 3 h;
In dichloromethane at 20℃; Inert atmosphere; Schlenk technique; Glovebox;

: 106-44-5
p-cresol

: 407-25-0
trifluoroacetic anhydride

: 1813-29-2
4-methylphenyl trifluoroacetate

Conditions

Conditions	Yield
erbium(III) triflate In acetonitrile at 20℃; for 8h;	100%
at 100℃; Cooling with ice;	93%

: 407-25-0
trifluoroacetic anhydride

: 100-51-6
benzyl alcohol

: 351-70-2
benzyl trifluoroacetate

Conditions

Conditions	Yield
erbium(III) triflate In acetonitrile at 20℃; for 0.166667h;	100%
With erbium(III) chloride for 2h; Heating;	99%
In diethyl ether at 0℃; for 2h; Inert atmosphere;	95%

: 407-25-0
trifluoroacetic anhydride

: 599-00-8
trifluoroacetic acid-d1

Conditions

Conditions	Yield
With water-d2 at -78℃;	100%
With water-d2
With water-d2 1.) 0 deg C, 2.) reflux, 30 min;

: 536-90-3
m-Anisidine

: 407-25-0
trifluoroacetic anhydride

: 14818-55-4
N-(3-methoxyphenyl)-2,2,2-trifluoroacetamide

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 0 - 20℃; for 0.75h;	100%
In diethyl ether
With pyridine In dichloromethane at 0 - 20℃; Inert atmosphere;
With triethylamine
at 20℃; for 3h; Inert atmosphere;

: 90-04-0
2-methoxy-phenylamine

: 407-25-0
trifluoroacetic anhydride

: 14815-12-4
N-(2-methoxyphenyl)-2,2,2-trifluoro-acetamide

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 0 - 20℃; for 0.75h;	100%
With pyridine In dichloromethane at 0 - 20℃; for 72h; Inert atmosphere;	99%
In diethyl ether
Stage #1: 2-methoxy-phenylamine With pyridine In dichloromethane at 0℃; for 0.5h; Stage #2: trifluoroacetic anhydride In dichloromethane at 0 - 30℃; for 1.25h;
With pyridine In dichloromethane at 0 - 20℃; for 1.25h;

: 118-92-3
anthranilic acid

: 407-25-0
trifluoroacetic anhydride

: 16062-71-8
2-trifluoromethyl-4H-3,1-benzoxazin-4-one

Conditions

Conditions	Yield
In neat (no solvent) at 130℃; for 6h; Sealed tube; Inert atmosphere;	100%
In chloroform for 1h; Reflux;	56%
In ethyl acetate

: 87-59-2
2,3-Dimethylaniline

: 407-25-0
trifluoroacetic anhydride

: 14719-31-4
N-(2,3-dimethylphenyl)-2,2,2-trifluoroacetamide

Conditions

Conditions	Yield
In dichloromethane for 1h; Further stages;	100%
With triethylamine In dichloromethane for 1h; Ambient temperature;	87%
In diethyl ether
In dichloromethane at 0 - 20℃; for 12h;

: 57-88-5
cholesterol

: 407-25-0
trifluoroacetic anhydride

: 2665-02-3
cholesteryl trifluoroacetate

Conditions

Conditions	Yield
erbium(III) triflate In acetonitrile at 20℃; for 4h;	100%

: 79-63-0
tirucallol

: 407-25-0
trifluoroacetic anhydride

: 10112-12-6
Lanosterin-trifluoracetat

Conditions

Conditions	Yield
With pyridine; dmap In dichloromethane at 0℃; for 0.333333h;	100%

: 32854-09-4
L-cystine dimethyl ester dihydrochloride

: 407-25-0
trifluoroacetic anhydride

: 1492-83-7
N,N'-bis(trifluoroacetyl)-L-cystine dimethyl ester

Conditions

Conditions	Yield
With trifluoroacetic acid at -5 - 20℃;	100%
In trifluoroacetic acid Ambient temperature;	98%
	90%
In trifluoroacetic acid

: 496-15-1
1-indoline

: 407-25-0
trifluoroacetic anhydride

: 90732-28-8
2,2,2-trifluoro-1-(indolin-1-yl)ethan-1-one

Conditions

Conditions	Yield
With triethylamine In dichloromethane	100%
In dichloromethane at 0℃; for 1h; Inert atmosphere;	100%
In benzene at 0 - 5℃;	96%

: 635-46-1
1,2,3,4-tetrahydroisoquinoline

: 407-25-0
trifluoroacetic anhydride

: 79066-90-3
1-(3,4-dihydroquinolin-1(2H)-yl)-2,2,2-trifluoroethanone

Conditions

Conditions	Yield
With triethylamine In diethyl ether at 0 - 20℃; for 5h;	100%
With triethylamine In diethyl ether at 20℃; for 5h;	100%
With triethylamine In diethyl ether at 0 - 20℃;	98%

: 60584-32-9, 124579-82-4
4,6-di-O-acetyl-3-O-methyl-D-glucal

: 407-25-0
trifluoroacetic anhydride

: 102634-07-1, 102634-08-2, 102634-09-3, 102649-49-0
Trifluoro-acetic acid (4R,5S,6R)-5-acetoxy-6-acetoxymethyl-4-methoxy-3-nitro-tetrahydro-pyran-2-yl ester

Conditions

Conditions	Yield
With ammonium nitrate for 1h;	100%

: 86296-23-3
N-(3,4-Dimethoxyphenylacetyl)tryptamine

: 407-25-0
trifluoroacetic anhydride

: C24H18F6N2O4

Conditions

Conditions	Yield
In benzene 1) 0 degC, 3 h, 2) 20 degC, 1 h;	100%

: 99-03-6
1-(3-aminophenyl)ethanone

: 407-25-0
trifluoroacetic anhydride

: 56915-87-8
3-trifluoroacetamidoacetophenone

Conditions

Conditions	Yield
With pyridine In dichloromethane at 0℃; for 0.5h;	100%
In N,N-dimethyl-formamide for 48h; Ambient temperature;	80%
With trifluoroacetic acid Heating;

: 98-16-8
3-trifluoromethylaniline

: 407-25-0
trifluoroacetic anhydride

: 2946-73-8
2,2,2-trifluoro-N-(3-(trifluoromethyl)phenyl)acetamide

Conditions

Conditions	Yield
With triethylamine In 2-methyltetrahydrofuran	100%
Stage #1: 3-trifluoromethylaniline; trifluoroacetic anhydride With pyridine In dichloromethane at 0 - 20℃; Stage #2: With sodium hydrogencarbonate In dichloromethane	98%
In N,N-dimethyl-formamide for 48h; Ambient temperature;	70%
With triethylamine In tetrahydrofuran at 0 - 20℃;	51.1%
In dichloromethane

: 2592-95-2
benzotriazol-1-ol

: 407-25-0
trifluoroacetic anhydride

: 1-trifluoroacetoxybenzotriazole

Conditions

Conditions	Yield
for 0.5h;	100%

: 114552-24-8
2-(5,8-Dimethoxy-quinolin-4-yl)-phenylamine

: 7087-68-5
N-ethyl-N,N-diisopropylamine

: 407-25-0
trifluoroacetic anhydride

: 114552-23-7
N-[2-(5,8-Dimethoxy-quinolin-4-yl)-phenyl]-2,2,2-trifluoro-acetamide

Conditions

Conditions	Yield
at 0℃; for 0.5h;	100%

...Expand

: 99-09-2
3-nitro-aniline

: 407-25-0
trifluoroacetic anhydride

: 25080-83-5
N-trifluoroacetic-3-nitroaniline

Conditions

Conditions	Yield
In pyridine; dichloromethane	100%
With pyridine In dichloromethane at 20℃; for 3h;	95%
In acetonitrile for 2h; Ambient temperature;

: 65197-65-1
4-Methyl-2H-1,4-thiazin-3-one

: 407-25-0
trifluoroacetic anhydride

: 82912-54-7
6-Trifluoroacetyl-4-methyl-2H-1,4-thiazin-3-one

Conditions

Conditions	Yield
With pyridine In chloroform for 1080h; Ambient temperature;	100%

: 60891-78-3
2-methyl-8-nitroindolizine

: 407-25-0
trifluoroacetic anhydride

: 115058-17-8
2,2,2-Trifluoro-1-(2-methyl-8-nitro-indolizin-3-yl)-ethanone

Conditions

Conditions	Yield
	100%

: 39798-26-0
1,2-O-isopropylidene-3-amino-3,5-dideoxy-α-D-ribofuranoside

: 407-25-0
trifluoroacetic anhydride

: 39798-31-7
3,5-dideoxy-3-(trifluoroacetamido)-1,2-O-isopropylidene-α-D-ribofuranose

Conditions

Conditions	Yield
In diethyl ether 1.) 0 deg C, 0.5 h, 2.) RT, 30 min;	100%

: 86-56-6
N,N-dimethyl-1-naphthalenamine

: 407-25-0
trifluoroacetic anhydride

: 115975-33-2
N,N-Dimethyl-2,4-bis(trifluoroacetyl)-1-naphthylamine

Conditions

Conditions	Yield
With pyridine In chloroform for 18h; Ambient temperature;	100%
With pyridine In chloroform for 19h; Ambient temperature; 2.5 eq. (CF3CO)2O;

: 6564-72-3
2,3,4,6-tetra-O-benzyl-D-glucopyranose

: 407-25-0
trifluoroacetic anhydride

: 125343-69-3
2,3,4,6-tetra-O-benzyl-1-O-(trifluoroacetyl)-α-D-glucopyranose

Conditions

Conditions	Yield
With sodium 2,2,2-trifluoroacetate for 0.5h; Heating;	100%

: 52485-06-0
3,4,6-tri-O-acetyl-D-glucal

: 407-25-0
trifluoroacetic anhydride

: 102633-91-0, 102633-92-1, 102633-93-2, 102633-94-3, 102633-95-4, 102633-96-5, 102633-97-6, 102633-98-7, 102633-99-8, 102634-00-4, 102634-01-5, 102634-02-6
Trifluoro-acetic acid (4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-nitro-tetrahydro-pyran-2-yl ester

Conditions

Conditions	Yield
With ammonium nitrate for 1h;	100%

: 111-87-5
octanol

: 407-25-0
trifluoroacetic anhydride

: 2561-21-9
n-octyl trifluoroacetate

Conditions

Conditions	Yield
erbium(III) triflate In acetonitrile at 20℃; for 2.5h;	100%
With erbium(III) chloride for 1.5h; Heating;	99%
With triethylamine In benzene at 25 - 30℃; for 1h;

Trifluoroacetic anhydride Chemical Properties

Product Name: Trifluoroacetic anhydride

Molecular Formula: C₄F₆O₃
Molecular Weight: 210.03g/mol
Mol File: 407-25-0.mol
Einecs: 206-982-9
Appearance: Clear, colorless liquid
Melting Point: -65 °C, 208 K, -85 °F
Boiling point: 40 °C, 313 K, 104 °F
Storage Temperature: 2-8°C
Density: 1.641 g/cm³
Index of Refraction: 1.291
Water Solubility: Hydrolysis
Sensitive: Moisture Sensitive
Surface Tension: 19.3 dyne/cm
Enthalpy of Vaporization: 28.41 kJ/mol
Vapour Pressure of Trifluoroacetic anhydride (CAS NO.407-25-0): 439 mmHg at 25 °C
Product Categories: Halogen compounds; Organics; Organic Fluorides; Acylation (GC Derivatizing Reagents); Analytical Chemistry; Fluorinated Building Blocks; Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds; GC Derivatizing Reagents; Synthetic Organic Chemistry

Trifluoroacetic anhydride Production

Trifluoroacetic anhydride (CAS NO.407-25-0) may be prepared from trifluoroacetic acid by dehydrating with excess α-halogenated acid chlorides. For example, with dichloroacetyl chloride:
2 CF₃COOH + Cl₂CHCOCl → (CF₃CO)₂O + Cl₂CHCOOH + HCl

Trifluoroacetic anhydride Toxicity Data With Reference

Trifluoroacetic anhydride (CAS NO.407-25-0) hasn't been listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.

Trifluoroacetic anhydride Safety Profile

Safety Information of Trifluoroacetic anhydride (CAS NO.407-25-0):
Hazard Codes: C,T
Risk Statements: 14-20-35-52/53-34-23/24/25
14: Reacts violently with water
20: Harmful by inhalation
23: Toxic by inhalation
24: Toxic in contact with skin
25: Toxic if swallowed
34: Causes burns
35: Causes severe burns
52: Harmful to aquatic organisms
53: May cause long-term adverse effects in the aquatic environment
Safety Statements: 26-36/37/39-43-45-61-9-8-28A-27
8: Keep container dry
9: Keep container in a well-ventilated
place
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
27: Take off immediately all contaminated clothing
28: After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
43: In case of fire, use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add - Never use water)
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

Trifluoroacetic anhydride Specification

Trifluoroacetic anhydride , its CAS NO. is 407-25-0,the synonyms is Aceticacid,trifluoro-,anhydride ; Anhydrid kyseliny trifluoroctove ; Anhydridkyselinytrifluoroctove ; Hexafluoroacetic anhydride ; Hexafluoroaceticanhydride ; Perfluoroacetic anhydride ; Perfluoroaceticanhydride ; Trifluoroacetic . In addition, Trifluoroacetic anhydride (CAS NO.407-25-0) could be stable under normal temperatures and pressures, and it absorbs moisture or water from the air. It is not compatible with water, metals, strong oxidizing agents, strong acids, strong bases, alcohols, alkali metals. And also prevent it to broken down into hazardous decomposition products: carbon monoxide, carbon dioxide, hydrogen fluoride gas, fluorine. It will not occur hazardous polymerization.

Product Name

Trifluoroacetic anhydride

Synthetic route

Trifluoroacetic anhydride Chemical Properties

Trifluoroacetic anhydride Production

Trifluoroacetic anhydride Toxicity Data With Reference

Trifluoroacetic anhydride Safety Profile

Trifluoroacetic anhydride Specification

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