Product Name

  • Name

    Tyramine

  • EINECS 200-115-8
  • CAS No. 51-67-2
  • Article Data83
  • CAS DataBase
  • Density 1.103 g/cm3
  • Solubility 1g / 95mL (15 °C) in water
  • Melting Point 155-163 °C
  • Formula C8H11NO
  • Boiling Point 325.2 °C at 760 mmHg
  • Molecular Weight 137.181
  • Flash Point 119.2 °C
  • Transport Information
  • Appearance white to light beige solid
  • Safety 26-36-37/39
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 51-67-2 (Tyramine)
  • Hazard Symbols IrritantXi
  • Synonyms p-Hydroxyphenylethylamine;p-beta-Aminoethylphenol;Uteramine;Tyrophagus lintneriMushroom mite is also indexed at this headingTyrosamine;4-Hydroxyphenyl ethylamine;4-Hydroxy-.beta.-phenylethylamine;beta-Hydroxyphenylethylamine;Phenol, 4- (2-aminoethyl)-;4-Hydroxyphenethylamine;p-.beta.-Aminoethylphenol;Phenol, 4-(2-aminoethyl)-;2-(4-hydroxyphenyl)ethylazanium;Tocosine;Benzeneethanamine, 4-hydroxy-;alpha-(4-Hydroxyphenyl)-beta-aminoethane;p-Hydroxy-Beta-Phenethylamine;Tyramine, 4-Hydroxyphenylethylamine;
  • PSA 46.25000
  • LogP 1.59370

Synthetic route

L-tyrosine
60-18-4

L-tyrosine

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With pyridoxal 5'-phosphate; aromatic L-amino acid decarboxylase In various solvent(s) at 30℃; for 48h;99%
at 300 - 340℃;
Bestrahlen der Kristalle mit Roentgen-Strahlen;
N-acetyltyramine
1202-66-0

N-acetyltyramine

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With ammonium bromide; ethylenediamine at 80℃; for 5h; Microwave irradiation; Inert atmosphere; neat (no solvent);98%
With recombinant Arabidopsis thaliana histone deacetylase 14 In aq. buffer at 30℃; pH=8; Reagent/catalyst; Enzymatic reaction;
(E)-3-(2-Hydroxy-phenyl)-N-[2-(4-hydroxy-phenyl)-ethyl]-acrylamide

(E)-3-(2-Hydroxy-phenyl)-N-[2-(4-hydroxy-phenyl)-ethyl]-acrylamide

A

tyrosamine
51-67-2

tyrosamine

B

coumarin
91-64-5

coumarin

Conditions
ConditionsYield
With acetic acid In methanol for 2h; Ambient temperature; Irradiation; other N-subsituted amides of o-hydroxy-trans-cinnamic acid;A 95%
B 100 % Spectr.
N-{2-[4-(tetrahydro-2H-pyran-2-yloxy)phenyl]ethyl}formamide
1521270-08-5

N-{2-[4-(tetrahydro-2H-pyran-2-yloxy)phenyl]ethyl}formamide

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With ethanol; sodium hydroxide at 78℃; for 8h; Reagent/catalyst; Temperature;87%
1-(benzyloxy)-4-(2-nitroethyl)benzene
99696-06-7

1-(benzyloxy)-4-(2-nitroethyl)benzene

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With ethanol; hydrogen at 100℃; Flow reactor;85%
formic acid
64-18-6

formic acid

nitromethane
75-52-5

nitromethane

phenol
108-95-2

phenol

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
Stage #1: formic acid; phenol With boron trifluoride In diethyl ether at 15℃; for 2h;
Stage #2: nitromethane With ammonium acetate In diethyl ether at 110℃; for 2h;
Stage #3: With hydrogen In ethanol at 50℃; for 4h; Temperature;
82.3%
Conditions
ConditionsYield
With 1,10-Phenanthroline; copper hydroxide In 1-methyl-pyrrolidin-2-one at 210℃; for 5h; Inert atmosphere; Green chemistry;68%
in Gegenwart von Fleischbruehe;
at 270℃;
(4-Hydroxyphenyl)acetaldehyd-dimethylhydrazon
74321-28-1

(4-Hydroxyphenyl)acetaldehyd-dimethylhydrazon

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With hydrogen; rhenium; nickel In methanol under 760 Torr; for 12h; Ambient temperature;58%
N-(p-hydroxyphenylethyl)-N-(6-bromo-3-hydroxy-4-methoxybenzyl)amine
179107-93-8

N-(p-hydroxyphenylethyl)-N-(6-bromo-3-hydroxy-4-methoxybenzyl)amine

A

tyrosamine
51-67-2

tyrosamine

B

2-bromoisovanillin
2973-59-3

2-bromoisovanillin

C

C16H16BrNO3

C16H16BrNO3

Conditions
ConditionsYield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; laccase from Trametes versicolor In 1,4-dioxane at 25℃; for 3h; pH=4.5;A 33%
B 37%
C 8%
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With hydrogenchloride; sodium nitrite
With hydrogenchloride; tin(IV) chloride; sodium nitrite anschliessend Erwaermen;
octopamine
104-14-3

octopamine

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With palladium on activated charcoal; acetic acid Hydrogenation;
3-(4-hydroxyphenyl)propanoic acid amide
23838-70-2

3-(4-hydroxyphenyl)propanoic acid amide

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With sodium hypochlorite
(E)-1-(4-hydroxyphenyl)-2-nitroethene
22568-49-6

(E)-1-(4-hydroxyphenyl)-2-nitroethene

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With sulfuric acid; acetic acid; platinum Hydrogenation;
4-(2-Nitrovinyl)benzoic acid methyl ester
22568-50-9

4-(2-Nitrovinyl)benzoic acid methyl ester

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With sulfuric acid; acetic acid; platinum Hydrogenation;
(4-hydroxy-phenyl)-acetaldehyde-(4-nitro-phenylhydrazone)
13033-75-5

(4-hydroxy-phenyl)-acetaldehyde-(4-nitro-phenylhydrazone)

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With sodium amalgam; ethanol; acetic acid
2-benzylamino-1-(4-hydroxy-phenyl)-ethanone; hydrochloride

2-benzylamino-1-(4-hydroxy-phenyl)-ethanone; hydrochloride

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With palladium on activated charcoal; acetic acid Hydrogenation;
Multi-step reaction with 2 steps
1: palladium/charcoal; ethanol / Hydrogenation
2: palladium/charcoal; acetic acid / Hydrogenation
View Scheme
9H-fluorene
86-73-7

9H-fluorene

L-tyrosine
60-18-4

L-tyrosine

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
at 280 - 290℃;
Diphenylmethane
101-81-5

Diphenylmethane

L-tyrosine
60-18-4

L-tyrosine

A

tyrosamine
51-67-2

tyrosamine

B

methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

Conditions
ConditionsYield
at 245℃;
Diphenylmethane
101-81-5

Diphenylmethane

L-tyrosine
60-18-4

L-tyrosine

diphenylamine
122-39-4

diphenylamine

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
at 260℃;
L-tyrosine
60-18-4

L-tyrosine

diphenylamine
122-39-4

diphenylamine

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
at 230℃;
L-tyrosine
60-18-4

L-tyrosine

A

tyrosamine
51-67-2

tyrosamine

B

methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

Conditions
ConditionsYield
at 270℃;
4-Methoxyphenethylamine
55-81-2

4-Methoxyphenethylamine

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With hydrogenchloride at 160 - 170℃;
With hydrogen iodide
With hydrogen bromide at 160℃;
With hydrogenchloride Heating;
With hydrogen bromide; acetic acid for 4h; Reflux;
2-(4-hydroxyphenyl)-1-nitroethane
37567-58-1

2-(4-hydroxyphenyl)-1-nitroethane

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol Product distribution;
L-tyrosine
60-18-4

L-tyrosine

A

tyrosamine
51-67-2

tyrosamine

B

carbon dioxide
124-38-9

carbon dioxide

Conditions
ConditionsYield
With Tyrosine decarboxylase apoenzyme; pyridoxal 5'-phosphate In water at 37℃; Product distribution; Effect of pH 5-6.2, other enzyme concentration and activity and temperature on reaction rate;
4-(β-Aminoethyl)benzene Oxide
73971-94-5

4-(β-Aminoethyl)benzene Oxide

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
In d(4)-methanol
L-tyrosine
60-18-4

L-tyrosine

petroleum

petroleum

tyrosamine
51-67-2

tyrosamine

Conditions
ConditionsYield
at 240 - 280℃; beim Destillieren;
tyrosamine
51-67-2

tyrosamine

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

N-t-butoxycarbonyl-tyramine
64318-28-1

N-t-butoxycarbonyl-tyramine

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran; methanol at 0 - 20℃;100%
In tetrahydrofuran for 3.5h;100%
With triethylamine In N,N-dimethyl-formamide99%
tyrosamine
51-67-2

tyrosamine

(4aS,6S,7R,7aS)-6-Acetoxy-7-methyl-1-oxo-1,4a,5,6,7,7a-hexahydro-cyclopenta[c]pyran-4-carboxylic acid methyl ester
91653-32-6

(4aS,6S,7R,7aS)-6-Acetoxy-7-methyl-1-oxo-1,4a,5,6,7,7a-hexahydro-cyclopenta[c]pyran-4-carboxylic acid methyl ester

(1S,2R,3S,5S)-3-Hydroxy-5-{(E)-2-[2-(4-hydroxy-phenyl)-ethylamino]-1-methoxycarbonyl-vinyl}-2-methyl-cyclopentanecarboxylic acid methyl ester

(1S,2R,3S,5S)-3-Hydroxy-5-{(E)-2-[2-(4-hydroxy-phenyl)-ethylamino]-1-methoxycarbonyl-vinyl}-2-methyl-cyclopentanecarboxylic acid methyl ester

Conditions
ConditionsYield
In methanol100%
tyrosamine
51-67-2

tyrosamine

benzaldehyde
100-52-7

benzaldehyde

N-benzyltyramine
52447-50-4

N-benzyltyramine

Conditions
ConditionsYield
Stage #1: tyrosamine; benzaldehyde In DMF (N,N-dimethyl-formamide); toluene
Stage #2: With sodium tetrahydroborate In tetrahydrofuran; methanol at 0 - 20℃; for 1h;
100%
Stage #1: tyrosamine; benzaldehyde In methanol for 2h; Heating / reflux;
Stage #2: With sodium tetrahydroborate In methanol at 0 - 20℃; Product distribution / selectivity;
91%
Stage #1: tyrosamine; benzaldehyde In methanol for 1h; Heating / reflux;
Stage #2: With sodium tetrahydroborate In methanol at 0 - 20℃; for 1h; Product distribution / selectivity;
61%
tyrosamine
51-67-2

tyrosamine

4-Nitrophenyl isocyanate
100-28-7

4-Nitrophenyl isocyanate

4-hydroxyphenethylamino-4-nitroanilinomethanone
259263-96-2

4-hydroxyphenethylamino-4-nitroanilinomethanone

Conditions
ConditionsYield
With pyridine at 0 - 20℃;100%
tyrosamine
51-67-2

tyrosamine

1-azido-2-(4-hydroxyphenyl)ethane
74447-34-0

1-azido-2-(4-hydroxyphenyl)ethane

Conditions
ConditionsYield
With methanol; copper(ll) sulfate pentahydrate; triflic azide; sodium hydrogencarbonate In water at 20℃;100%
With fluorosulfonyl azide; potassium hydrogencarbonate In tert-butyl methyl ether; water; N,N-dimethyl-formamide at 20℃; for 0.0833333h;86%
With imidazole-1-sulfonyl azide hydrochloride; potassium carbonate; copper(II) sulfate In methanol at 20℃; for 4h;84%
tyrosamine
51-67-2

tyrosamine

phenyl chloroformate
1885-14-9

phenyl chloroformate

phenyl N-[2-(4-hydroxyphenyl)ethyl]carbamate
1184576-50-8

phenyl N-[2-(4-hydroxyphenyl)ethyl]carbamate

Conditions
ConditionsYield
With sodium hydrogencarbonate In 1,4-dioxane; water at 20℃; for 4h; Inert atmosphere;100%
tyrosamine
51-67-2

tyrosamine

methyl 3-(2-chlorophenyl)-1-(2-chloropyrimidin-4-yl)-1H-pyrazole-4-carboxylate
1445890-31-2

methyl 3-(2-chlorophenyl)-1-(2-chloropyrimidin-4-yl)-1H-pyrazole-4-carboxylate

methyl 3-(2-chlorophenyl)-1-(2-{[2-(4-hydroxyphenyl)ethyl]amino}pyrimidin-4-yl)-1H-pyrazole-4-carboxylate
1445890-33-4

methyl 3-(2-chlorophenyl)-1-(2-{[2-(4-hydroxyphenyl)ethyl]amino}pyrimidin-4-yl)-1H-pyrazole-4-carboxylate

Conditions
ConditionsYield
In acetonitrile at 80℃;100%
tyrosamine
51-67-2

tyrosamine

propionyl chloride
79-03-8

propionyl chloride

N-(4-hydroxyphenylethyl)propionamide
60394-18-5

N-(4-hydroxyphenylethyl)propionamide

Conditions
ConditionsYield
Stage #1: tyrosamine With potassium carbonate In tetrahydrofuran; water at 20℃; for 1h; Inert atmosphere;
Stage #2: propionyl chloride In tetrahydrofuran; water for 2h; Inert atmosphere;
100%
tyrosamine
51-67-2

tyrosamine

methyl chloroformate
79-22-1

methyl chloroformate

4-hydroxyphenyl-2-ethylcarbamic acid methyl ester
62372-08-1

4-hydroxyphenyl-2-ethylcarbamic acid methyl ester

Conditions
ConditionsYield
With water; sodium hydrogencarbonate In tetrahydrofuran at 0℃; for 3h;100%
With N-ethyl-N,N-diisopropylamine In dichloromethane Inert atmosphere; Cooling with ice;52%
tyrosamine
51-67-2

tyrosamine

Thioctic acid
1077-28-7, 62-46-4

Thioctic acid

5-(1,2-dithiolan-3-yl)-N-(4-hydroxyphenethyl)pentanamide

5-(1,2-dithiolan-3-yl)-N-(4-hydroxyphenethyl)pentanamide

Conditions
ConditionsYield
Stage #1: Thioctic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In dichloromethane; N,N-dimethyl-formamide at -20 - 20℃; for 0.5h; Schlenk technique; Inert atmosphere;
Stage #2: tyrosamine In dichloromethane; N,N-dimethyl-formamide at 20℃; Schlenk technique; Inert atmosphere;
100%
Stage #1: Thioctic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran for 0.5h;
Stage #2: tyrosamine In tetrahydrofuran at 20℃; for 12h;
75%
tyrosamine
51-67-2

tyrosamine

tolfenamic Acid
13710-19-5

tolfenamic Acid

C14H12ClNO2*C8H11NO

C14H12ClNO2*C8H11NO

Conditions
ConditionsYield
In methanol at 20℃;100%
tyrosamine
51-67-2

tyrosamine

C17H17ClN2O3

C17H17ClN2O3

C17H17ClN2O3*C8H11NO

C17H17ClN2O3*C8H11NO

Conditions
ConditionsYield
In methanol at 20℃;100%
tyrosamine
51-67-2

tyrosamine

1,4,5,8-naphthalenetetracarboxylic dianhydride
81-30-1

1,4,5,8-naphthalenetetracarboxylic dianhydride

N,N'-bis[2-(4-hydroxyphenyl)ethyl]-1,4,5,8-naphthalenetetracarboxylic acid diimide
1187488-10-3

N,N'-bis[2-(4-hydroxyphenyl)ethyl]-1,4,5,8-naphthalenetetracarboxylic acid diimide

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane; N,N-dimethyl-formamide Inert atmosphere; Reflux;99%
tyrosamine
51-67-2

tyrosamine

4-(2-amino-ethyl)-2,6-diiodo-phenol; hydriodide

4-(2-amino-ethyl)-2,6-diiodo-phenol; hydriodide

Conditions
ConditionsYield
With dihydrogen peroxide; iodine In water at 55℃; for 3h;99%
tyrosamine
51-67-2

tyrosamine

dithio-bis(ethyl 1H-imidazole-1-carboxylate)
877865-61-7

dithio-bis(ethyl 1H-imidazole-1-carboxylate)

tyramine-DIC
1375482-36-2

tyramine-DIC

Conditions
ConditionsYield
In isopropyl alcohol at 40℃; for 24h;99%
In isopropyl alcohol at 40℃; for 24h;59%
tyrosamine
51-67-2

tyrosamine

ethyl acetate
141-78-6

ethyl acetate

N-acetyltyramine
1202-66-0

N-acetyltyramine

Conditions
ConditionsYield
With Trimethylacetic acid at 90℃; for 24h; Inert atmosphere; chemoselective reaction;99%
tyrosamine
51-67-2

tyrosamine

racemic trans-1-(tert-butoxycarbonyl)pyrrolidine-3,4-dicarboxylic acid

racemic trans-1-(tert-butoxycarbonyl)pyrrolidine-3,4-dicarboxylic acid

tert-butyl trans-3,4-bis((4-hydroxyphenethyl)carbamoyl)pyrrolidine-1-carboxylate

tert-butyl trans-3,4-bis((4-hydroxyphenethyl)carbamoyl)pyrrolidine-1-carboxylate

Conditions
ConditionsYield
With 2,6-dimethylpyridine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 23℃; for 16h; Inert atmosphere;99%
tyrosamine
51-67-2

tyrosamine

9-benzoyl-9H-carbazole
19264-68-7

9-benzoyl-9H-carbazole

N-<2-(4-hydroxyphenyl)ethyl>benzamide
41859-54-5

N-<2-(4-hydroxyphenyl)ethyl>benzamide

Conditions
ConditionsYield
In tetrahydrofuran at 30℃; for 24h; chemoselective reaction;99%
tyrosamine
51-67-2

tyrosamine

D,L-sulforaphane
4478-93-7

D,L-sulforaphane

C14H22N2O2S2

C14H22N2O2S2

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 10h; Inert atmosphere;98.62%
tyrosamine
51-67-2

tyrosamine

3,5-dibromo-4-hydroxy-β-phenethylamine
134755-34-3

3,5-dibromo-4-hydroxy-β-phenethylamine

Conditions
ConditionsYield
With pyridine; pyridinium hydrobromide perbromide In chloroform for 24h;98%
With bromine In acetic acid98%
With bromine; acetic acid93%
With tetrabuthylammonium tribromide In methanol; dichloromethane at 20℃; for 0.5h;63%
With bromine; acetic acid
tyrosamine
51-67-2

tyrosamine

(tert-butoxycarbonyl)-L-phenylalanine N-hydroxysuccinimide ester
3674-06-4, 3674-18-8, 74124-84-8

(tert-butoxycarbonyl)-L-phenylalanine N-hydroxysuccinimide ester

N-(tert-Butoxycarbonyl)-L-phenyl-alanyltyramide
89088-14-2

N-(tert-Butoxycarbonyl)-L-phenyl-alanyltyramide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In ethyl acetate at 25℃; for 20h;98%
tyrosamine
51-67-2

tyrosamine

N-acetyl-1,3-oxazol-2-one
60759-49-1

N-acetyl-1,3-oxazol-2-one

N-acetyltyramine
1202-66-0

N-acetyltyramine

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 1h; Ambient temperature;98%
In tetrahydrofuran for 0.5h; Ambient temperature;98%
tyrosamine
51-67-2

tyrosamine

tert-butylisonitrile
119072-55-8, 7188-38-7

tert-butylisonitrile

2-(2-formyl-phenyl)-benzoic acid
6720-26-9

2-(2-formyl-phenyl)-benzoic acid

N-tert-butyl-6-(4-hydroxyphenethyl)-7-oxo-6,7-dihydro-5H-dibenzo[c,e]azepine-5-carboxamide
1283600-63-4

N-tert-butyl-6-(4-hydroxyphenethyl)-7-oxo-6,7-dihydro-5H-dibenzo[c,e]azepine-5-carboxamide

Conditions
ConditionsYield
With sodium sulfate In 2,2,2-trifluoroethanol at 110℃; for 0.833333h; Ugi 4CR reaction; Sealed; Inert atmosphere; Irradiation;98%
tyrosamine
51-67-2

tyrosamine

Methyl formate
107-31-3

Methyl formate

N-[2-(4-hydroxyphenyl)ethyl]formamide
13062-78-7

N-[2-(4-hydroxyphenyl)ethyl]formamide

Conditions
ConditionsYield
In dimethyl sulfoxide at 20℃;98%
In dimethyl sulfoxide at 20℃; for 10h;92%
tyrosamine
51-67-2

tyrosamine

3-nitro-benzaldehyde
99-61-6

3-nitro-benzaldehyde

N-(3-nitrobenzylidene)-2-(4-hydroxyphenyl)ethanamine

N-(3-nitrobenzylidene)-2-(4-hydroxyphenyl)ethanamine

Conditions
ConditionsYield
for 24h; Reflux;98%
In ethanol for 24h; Reflux;60%
In ethanol for 24h; Reflux;
succinic acid anhydride
108-30-5

succinic acid anhydride

tyrosamine
51-67-2

tyrosamine

N-(4-hydroxyphenethyl)succinimide

N-(4-hydroxyphenethyl)succinimide

Conditions
ConditionsYield
at 140℃; for 4h; Reagent/catalyst; Temperature;98%
tyrosamine
51-67-2

tyrosamine

3,4,5,6-Tetrahydrophthalic anhydride
2426-02-0

3,4,5,6-Tetrahydrophthalic anhydride

N-(4-hydroxyphenethyl)-3,4,5,6-tetrahydrophthalimide

N-(4-hydroxyphenethyl)-3,4,5,6-tetrahydrophthalimide

Conditions
ConditionsYield
at 140℃; for 4h; Reagent/catalyst; Temperature;98%

Tyramine Specification

The IUPAC name of Tyramine is 4-(2-aminoethyl)phenol. With the CAS registry number 51-67-2, it is also named as Benzeneethanamine, 4-hydroxy-. The product's categories are Anilines, Aromatic Amines and Nitro Compounds. Besides, it is white to light beige solid, which should be stored in sealed, dark place. It is stable and incompatible with strong acids, strong oxidizing agents. In addition, its molecular formula is C8H11NO and molecular weight is 137.18.

The other characteristics of this product can be summarized as: (1)EINECS: 200-115-8; (2)ACD/LogP: 0.72; (3)# of Rule of 5 Violations: 0; (4)ACD/LogD (pH 5.5): -2.36; (5)ACD/LogD (pH 7.4): -1.82; (6)ACD/BCF (pH 5.5): 1; (7)ACD/BCF (pH 7.4): 1; (8)ACD/KOC (pH 5.5): 1; (9)ACD/KOC (pH 7.4): 1; (10)#H bond acceptors: 2; (11)#H bond donors: 3; (12)#Freely Rotating Bonds: 4; (13)Index of Refraction: 1.577; (14)Molar Refractivity: 41.21 cm3; (15)Molar Volume: 124.3 cm3; (16)Surface Tension: 48.3 dyne/cm; (17)Density: 1.103 g/cm3; (18)Flash Point: 119.2 °C; (19)Melting point: 155-163 °C; (20)Water Solubility: 1g / 95mL (15 °C); (21)Enthalpy of Vaporization: 58.99 kJ/mol; (22)Boiling Point: 325.2 °C at 760 mmHg; (23)Vapour Pressure: 0.000123 mmHg at 25 °C.

Preparation of Tyramine: this chemical occurs widely in plants and animals and is metabolized by the enzyme monoamine oxidase. Moreover, it is often produced by the decarboxylation of tyrosine during fermentation or decay. It also can be produced by the deoxidization of P-Hydroxybenzyl cyanide.

Uses of Tyramine: this chemical is used as intermediate of Bezafibrate. It is also used in organic synthesis. It can be used for the contraction of uterus, peripheral nerves, and for elevation of blood pressure in medical treatment. Additionally, it can react with Formaldehyde to get 4-(2-Dimethylamino-ethyl)-phenol.



This reaction needs H2, 10 percent Pd/C and Methanol at temperature of 20 °C. The yield is 93 %.

When you are using this chemical, please be cautious about it as the following: it is irritating to eyes, respiratory system and skin. In case of contact with eyes, please rinse immediately with plenty of water and seek medical advice. And you should wear suitable protective clothing, gloves and eye/face protection.

People can use the following data to convert to the molecule structure.
(1)SMILES: Oc1ccc(cc1)CCN
(2)InChI: InChI=1/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2
(3)InChIKey: DZGWFCGJZKJUFP-UHFFFAOYAB
(4)Std. InChI: InChI=1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2
(5)Std. InChIKey: DZGWFCGJZKJUFP-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo subcutaneous 30mg/kg (30mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1412, 1935.
mouse LD50 intracervical 30mg/kg (30mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Tohoku Yakka Daigaku Kenkyu Nempo. Annual Report of the Tohoku College of Pharmacy. Vol. 27, Pg. 131, 1980.
mouse LD50 intravenous 229mg/kg (229mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Acta Pharmacologica et Toxicologica. Vol. 38, Pg. 474, 1976.
mouse LDLo intraperitoneal 800mg/kg (800mg/kg)   Journal of Physiology. Vol. 76, Pg. 224, 1932.
mouse LDLo subcutaneous 225mg/kg (225mg/kg)   "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. -, 1965.
mouse LDLo unreported 2200mg/kg (2200mg/kg) AUTONOMIC NERVOUS SYSTEM: SYMPATHOMIMETIC Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 153, Pg. 161, 1930.
rabbit LD50 intravenous 300mg/kg (300mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 691, 1986.

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