triisopropyl phosphite supplier

Name
Triisopropyl phosphite
EINECS 204-130-0
CAS No. 116-17-6
Article Data33
CAS DataBase
Density 0.844 g/cm³
Solubility insoluble in water
Melting Point
Formula C₉H₂₁O₃P
Boiling Point 181.4 °C at 760 mmHg
Molecular Weight 208.238
Flash Point 67.8 °C
Transport Information UN 3278 6.1/PG 3
Appearance clear to slightly turbid colorless liquid
Safety 37-46-45-36/37
Risk Codes 25-38-68
Molecular Structure
Hazard Symbols T, F
Synonyms Isopropylphosphite ((C3H7O)3P) (6CI,7CI);Phosphorous acid, triisopropyl ester (8CI);Isopropyl phosphite;NSC 6516;Tri-2-propyl phosphite;Triisopropoxyphosphine;
PSA 41.28000
LogP 3.48830

Synthetic route

: 117965-98-7
S-acetyl O,O-diisopropyl phosphorothioite

: 67-63-0
isopropyl alcohol

: 116-17-6
triisopropyl phosphite

Conditions

Conditions	Yield
at 0℃;	64%

: 67-63-0
isopropyl alcohol

A: 41662-51-5
diisopropyl phosphorochloridite

B: 116-17-6
triisopropyl phosphite

Conditions

Conditions	Yield
With pyridine; phosphorus trichloride In Petroleum ether for 3h; Ambient temperature;	A 34% B n/a

: 67-63-0
isopropyl alcohol

: 116-17-6
triisopropyl phosphite

Conditions

Conditions	Yield
With pyridine; diethyl ether; phosphorus trichloride
With diethyl ether; 2,3-Dimethylaniline; phosphorus trichloride
With triethylamine; Petroleum ether; phosphorus trichloride

: 60-29-7
diethyl ether

: 121-69-7
N,N-dimethyl-aniline

: 67-63-0
isopropyl alcohol

: 7719-12-2, 52843-90-0
phosphorus trichloride

: 116-17-6
triisopropyl phosphite

...Expand

: 110-82-7
cyclohexane

: 121-69-7
N,N-dimethyl-aniline

: 67-63-0
isopropyl alcohol

: 7719-12-2, 52843-90-0
phosphorus trichloride

: 116-17-6
triisopropyl phosphite

Conditions

Conditions	Yield
at 22 - 23℃;

...Expand

: 121-44-8
triethylamine

: 67-63-0
isopropyl alcohol

: 7719-12-2, 52843-90-0
phosphorus trichloride

petroleum ether: petroleum ether

: 116-17-6
triisopropyl phosphite

...Expand

: 67-63-0
isopropyl alcohol

: 211055-34-4
O,O'-diisopropyl N,N-diisopropylphosphoramidite

: 116-17-6
triisopropyl phosphite

Conditions

Conditions	Yield
With N,N-dimethylbenzylammonium fluoride In acetonitrile at 20℃; Kinetics; Further Variations:; Reagents;

: 41662-51-5
diisopropyl phosphorochloridite

: 116-17-6
triisopropyl phosphite

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 2: 64 percent / 0 °C View Scheme

: Fe2(η-Cp)(CO)2(P(OPr-i)3)

: 121-45-9
phosphorous acid trimethyl ester

A: {(C5H5)Fe(CO)P(OCH3)3}2

B: 116-17-6
triisopropyl phosphite

Conditions

Conditions	Yield
In cyclohexane byproducts: CO; Irradiation (UV/VIS); irradn. of Fe complex and phosphite ligand in cyclohexane at room temp.; not isolated, detected by IR;

...Expand

: 116-17-6
triisopropyl phosphite

: 513-02-0
triisopropyl phosphate

Conditions

Conditions	Yield
With water; 7,7',8,8'-tetracyanoquinodimethane In acetonitrile at 25℃; Rate constant;	100%
With water; 7,7',8,8'-tetracyanoquinodimethane In acetonitrile	100%
With 1-methyl-3-(4-((2,4,6-triisopropylphenyl)tellanyl)benzyl)-1H-imidazol-3-ium hexafluorophosphate; Rose Bengal lactone at 15℃; for 2.5h; Irradiation; Ionic liquid;	99%

: 116-17-6
triisopropyl phosphite

: 106-95-6
allyl bromide

: 1067-70-5
Diisopropyl allylphosphonate

Conditions

Conditions	Yield
With 2,6-di-tert-butyl-4-methyl-phenol at 115℃; for 16h;	100%
for 16h; Heating;	95%

: 116-17-6
triisopropyl phosphite

: 74-88-4
methyl iodide

: 1445-75-6
diisopropyl methanephosphonate

Conditions

Conditions	Yield
at 60 - 100℃; for 1h; Inert atmosphere;	100%
at 100℃; for 1h; Inert atmosphere;	100%
In neat (no solvent) at 100℃; for 0.138833h; Arbuzov Reaction; Flow reactor;	99%

: 116-17-6
triisopropyl phosphite

: 92659-86-4
methyl [(diisopropoxy)phosphinyl]dithioformate

: 128396-05-4
triisopropyloxyphosphoranylidene methylsulfanyl diisopropylmethylphosphonate

Conditions

Conditions	Yield
In tetrahydrofuran at 0 - 20℃;	100%
In tetrahydrofuran at 0 - 20℃;	100 % Spectr.

: 116-17-6
triisopropyl phosphite

: 6780-38-7
N-phthaloylglycine chloride

: 129034-54-4
diisopropyl phthalylglycylphosphonate

Conditions

Conditions	Yield
	100%

: 116-17-6
triisopropyl phosphite

: 94-41-7
benzalacetophenone

: diisopropyl 3-oxo-1,3-diphenylpropylphosphonate

Conditions

Conditions	Yield
With acetic acid	100%

: 116-17-6
triisopropyl phosphite

: 3,3,3-Trifluoro-2-[(E)-4-methoxy-benzenesulfonylimino]-propionic acid methyl ester

: 3,3,3-trifluoro-2-(4-methoxy-benzenesulfonyl)-2-(triisopropoxy-λ5-phosphanylideneamino)-propionic acid methyl ester

Conditions

Conditions	Yield
In benzene at 20℃; for 0.5h;	100%

: 116-17-6
triisopropyl phosphite

: HRh{(P(OCH3)2O)2H}2(CO)

: HRh{(P(OCH3)2O)2H}2(P(OCH(CH3)2)3)

Conditions

Conditions	Yield
In diethyl ether byproducts: CO; (N2); stirring for 4 d at ambiente temp. overnight; evapn. to dryness; (31)C-, (31)P-NMR; IR;	100%

: 931-53-3
Cyclohexyl isocyanide

: 116-17-6
triisopropyl phosphite

: 4755-77-5
Ethyl oxalyl chloride

: 1146344-31-1
3-cyclohexylimino-2-(diisopropoxy-phosphoryloxy)-acrylic acid ethyl ester

Conditions

Conditions	Yield
Stage #1: Cyclohexyl isocyanide; Ethyl oxalyl chloride Nef reaction; Heating; Stage #2: triisopropyl phosphite Perkow-type reaction;	100%
Stage #1: Cyclohexyl isocyanide; Ethyl oxalyl chloride Nef reaction; Heating; Stage #2: triisopropyl phosphite Perkow reaction;	100%

...Expand

: 116-17-6
triisopropyl phosphite

: 119072-55-8, 7188-38-7
tert-butylisonitrile

: 4755-77-5
Ethyl oxalyl chloride

: 1146344-35-5
3-tert-butylimino-2-(diisopropoxy-phosphoryloxy)-acrylic acid ethyl ester

Conditions

Conditions	Yield
Stage #1: tert-butylisonitrile; Ethyl oxalyl chloride Nef reaction; Heating; Stage #2: triisopropyl phosphite Perkow-type reaction;	100%
Stage #1: tert-butylisonitrile; Ethyl oxalyl chloride Nef reaction; Heating; Stage #2: triisopropyl phosphite Perkow reaction;	100%

...Expand

: formyl azide

: 116-17-6
triisopropyl phosphite

: 1380235-06-2
C10H22NO4P

Conditions

Conditions	Yield
In chloroform-d1 at -10 - 20℃; for 0.5h;	100%

: 116-17-6
triisopropyl phosphite

: 556-96-7
5-bromo-1,3-xylene

: 1393678-00-6
C14H23O3P

Conditions

Conditions	Yield
With nickel dibromide at 150℃; for 3h; Inert atmosphere;	100%

: bis(η3-allyl-μ-chloropalladium(II))

: 116-17-6
triisopropyl phosphite

: 557-40-4
Allyl ether

: Pd(η2:η2-diallyl ether){P(OiPr)3}

Conditions

Conditions	Yield
Stage #1: bis(η3-allyl-μ-chloropalladium(II)) With sodium cyclopentadienide In tetrahydrofuran at -20 - 20℃; for 1.5h; Inert atmosphere; Schlenk technique; Stage #2: triisopropyl phosphite; Allyl ether In tetrahydrofuran at 20 - 80℃; for 6.5h; Inert atmosphere; Schlenk technique;	100%

...Expand

: 116-17-6
triisopropyl phosphite

: 103-63-9
1-phenyl-2-bromoethane

: 66325-70-0
diisopropyl 2-phenylethylphosphonate

Conditions

Conditions	Yield
In neat (no solvent) at 120℃; for 24h; Sealed tube; Inert atmosphere;	100%

: 116-17-6
triisopropyl phosphite

: 134833-83-3
2-bromo-N-methoxy-N-methyl-acetamide

: C10H22NO5P

Conditions

Conditions	Yield
In neat (no solvent) at 120℃; for 24h;	100%

: 116-17-6
triisopropyl phosphite

: 553-94-6
4-bromo-m-xylene

: (2,5-dimethylphenyl)diisopropyl phosphonate

Conditions

Conditions	Yield
With nickel dibromide at 150℃; for 3h; Inert atmosphere;	100%

: 116-17-6
triisopropyl phosphite

: 107-59-5
tert-Butyl chloroacetate

: 103717-28-8
tert-butyl 2-(diisopropoxyphosphoryl)acetate

Conditions

Conditions	Yield
In dichloromethane for 3h; Heating;	100%

: 116-17-6
triisopropyl phosphite

: methyl-4-(2-ethylbutoxy)-8-methylquinoline-2-carboxylate

: methyl 8-((diisopropoxyphosphoryl)methyl)-4-(2-ethylbutoxy)quinoline-2-carboxylate

Conditions

Conditions	Yield
at 70℃; for 3h; Inert atmosphere;	100%

: 116-17-6
triisopropyl phosphite

: 75-03-6
ethyl iodide

: 1067-69-2
diisopropyl ethylphosphonate

Conditions

Conditions	Yield
In neat (no solvent) at 150℃; for 0.138833h; Temperature; Arbuzov Reaction; Flow reactor;	99%
at 160℃; for 12h;	88%

: 542-69-8
1-iodo-butane

: 116-17-6
triisopropyl phosphite

: 52468-61-8
diisopropyl n-butylphosphonate

Conditions

Conditions	Yield
In neat (no solvent) at 150℃; for 0.138833h; Arbuzov Reaction; Flow reactor;	99%
for 0.0833333h; Michaelis-Arbuzov reaction; microwave irradiation;	96%

: 116-17-6
triisopropyl phosphite

: 107-08-4
1-iodo-propane

: 18812-55-0
diisopropyl n-propylphosphonate

Conditions

Conditions	Yield
In neat (no solvent) at 150℃; for 0.138833h; Arbuzov Reaction; Flow reactor;	99%
for 0.0833333h; Michaelis-Arbuzov reaction; microwave irradiation;	98%

: 91-22-5
quinoline

: 116-17-6
triisopropyl phosphite

: 1885-14-9
phenyl chloroformate

: 2-(diisopropoxy-phosphoryl)-2H-quinoline-1-carboxylic acid phenyl ester

Conditions

Conditions	Yield
	99%

...Expand

: 116-17-6
triisopropyl phosphite

: 64827-21-0, 84414-96-0
cis-[Pt(p-CH3C6H4)2(S(CH3)2)2]

: 71-43-2
benzene

: cis-[Pt(p-MeC6H4)2(P(O(i)Pr)3)(SMe2)]

: cis-[Pt(p-MeC6H4)2(P(O(i)Pr)3)2]*0.5C6H6

Conditions

Conditions	Yield
In benzene byproducts: S(CH3)2; addn. of a soln. of 2 equivs. phosphite in benzene to a soln. of platinum complex in benzene, stirring at room temp. for 1 h; evapn. in vac.; elem. anal.;	A 0% B 99%

...Expand

: bis[dimethyl(μ-dimethylsulfide)platinum(II)]

: 116-17-6
triisopropyl phosphite

: 71-43-2
benzene

: cis-[PtMe2(P(O(i)Pr)3)2]*0.2benzene

Conditions

Conditions	Yield
In benzene byproducts: S(CH3)2; addn. of a soln. of 4 equivs. phosphite in benzene to a soln. of platinum complex in benzene, stirring at room temp. for 1 h; evapn. in vac.; elem. anal.;	99%

...Expand

: bis[dimethyl(μ-dimethylsulfide)platinum(II)]

: 116-17-6
triisopropyl phosphite

: 1052272-29-3
cis-[PtMe2(P(O(i)Pr)3)(SMe2)]

Conditions

Conditions	Yield
In benzene byproducts: S(CH3)2; addn. of a soln. of 2 equivs. phosphite in benzene to a soln. of platinum complex in benzene, stirring at room temp. for 1 h; evapn. in vac.; elem. anal.;	99%

: 116-17-6
triisopropyl phosphite

: 1233573-31-3
[Pt(p-MeC6H4)(2-phenylpyridinate)(SMe2)]

: 1338533-15-5
[Pt(p-MeC6H4)(2-phenylpyridyl(-1H))(P(O(i-Pr))3)]

Conditions

Conditions	Yield
In acetone addn. of P(O(i-Pr))3 to soln. of Pt(p-MeC6H4)(C6H4C5H4N)(SMe2) in acetone, stirring for 1 h; removal of solvent under reduced pressure, trituration with cold acetone, drying under vac.; as oil;	99%
In dichloromethane Kinetics; addn. of P(O(i-Pr))3 to soln. of Pt(p-MeC6H4)(C6H4C5H4N)(SMe2) in CH2Cl2at different temps. (5, 10, 15, 20, 25, 30 and 35°C), rapid stir ring; monitoring by UV;

: 116-17-6
triisopropyl phosphite

: 61859-90-3
4,4,4-trifluoro-3-(trifluoromethyl)-2-butenenitrile

: 1363721-11-2
4,4,4-trifluoro-3-(trifluoromethyl)-2-(triisopropoxyphosphoranylidene)butanenitrile

Conditions

Conditions	Yield
In hexane at 20℃; for 168h; Inert atmosphere;	99%

: 116-17-6
triisopropyl phosphite

: 619-44-3
methyl 4-iodobenzoate

: 1073561-84-8
diisopropyl (4-methoxycarbonylphenyl)phosphonate

Conditions

Conditions	Yield
With tetrabutyl-ammonium chloride In N,N-dimethyl-formamide at 20℃; for 5h; Electrolysis; Inert atmosphere;	99%

: 116-17-6
triisopropyl phosphite

: 589-15-1
1-bromomethyl-4-bromobenzene

: 50289-57-1
diisopropyl (4-bromophenyl)methylphosphonate

Conditions

Conditions	Yield
at 165℃; for 2.5h; Michaelis-Arbuzov Synthesis; Inert atmosphere;	99%

: 116-17-6
triisopropyl phosphite

: 96-32-2
bromoacetic acid methyl ester

: 72946-10-2
diisopropyl (methoxycarbonylmethyl)phosphonate

Conditions

Conditions	Yield
In neat (no solvent) at 120 - 130℃; for 4h; Inert atmosphere; Schlenk technique; Glovebox;	98%

triisopropyl phosphite Chemical Properties

Triisopropyl phosphitet is also called phosphorous acid tris(1-methylethyl) ester or triisopropoxyphosphine

Molecular Formula: C₉H₂₁O₃P
Formula Weight: 208.24
Boiling point : 63-64 °C 11 mm Hg(lit.)
Density : 0.914
Vapor pressure : <2 mm Hg ( 20 °C)
Refractive index : n20/D 1.411(lit.)
Fp : 154 °F
Water Solubility : Insoluble
Sensitive : Moisture Sensitive
BRN : 1701528

triisopropyl phosphite Safety Profile

Hazard Codes : T,F
Risk Statements : 25-38-68
Safety Statements : 37-46-45-36/37
RIDADR : UN 3278 6.1/PG 3
WGK Germany : 3
RTECS : TH2800000
F : 1-10
Hazard Note : Toxic/Flammable/Moisture Sensitive/
HazardClass : 3
PackingGroup : III

triisopropyl phosphite Specification

FIRE FIGHTING MEASURES
When triisopropyl phosphite is in any fire,please wear a self-contained breathing apparatus in pressure-demand, and full protective gear.It will burn if involved in a fire because it's combustible liquid.
Extinguishing Method:Use water spray, dry chemical, carbon dioxide, or chemical foam.

Product Name

Triisopropyl phosphite

Synthetic route

triisopropyl phosphite Chemical Properties

triisopropyl phosphite Safety Profile

triisopropyl phosphite Specification

Related Products

Hot Products