NADPH oxidase-derived superoxide (O2.-) generation and oxidative stress is usually considered as an important factor to the pathogenesis of inflammatory diseases. Quercetin, widely known for their anti-oxidant and anti-inflammatory properties in vitro and in vivo, is recently identified to induc...

Quercetin, a natural polyphenol with strong antioxidant activity, was loaded in Eudragit-coated liposomes conceived for intestinal delivery. Eudragit was used to form a protective shell on the surface of liposomes to resist gastric environment and allow the delivery of quercetin to the intestine...

Polyphenols synthesized by plants and fungi have various pharmacological effects. The ability of polyphenols to modulate sirtuins has gained considerable interest due to the role of sirtuins in aging, insulin sensitivity, lipid metabolism, inflammation, and cancer. In particular, sirtuin 6 (SIRT...

Pathogenic microorganisms have emerged as Multi Drug Resistant (MDR) and in the past years the infectious diseases caused by MDR have increased dramatically. The aim of this study is to investigate the antibacterial potential of Allium cepa and isolated quercetin along with molecular docking wit...

Although quercetin has numerous biological benefits, including preventing muscle atrophy due to disuse, no reports have been published to date about the preventive effects and molecular mechanisms underlying drug-induced muscle atrophy. Highly soluble and bioavailable quercetin glycosides (QGs) ...

Supercritical carbon dioxide has been used to develop two methods for the impregnation of porous silica beads with a natural antioxidant, quercetin. These methods involved batch and semi-continuous supercritical impregnations. The first experiments performed in batch mode helped to understand th...

Diabetic nephropathy (DN) is one of the most common microvascular complications of diabetes and the leading cause of end-stage renal disease. The proliferation of glomerular mesangial cells (MCs) is a common and prominent pathological change of DN, which takes place at the early stage. Quercetin...

In the present work, we report the antioxidant, antimicrobial and cytotoxic activities of quercetin-capped gold nanoparticles (AuNPsQct). The synthesis of AuNPsQct was confirmed by UV–Vis spectroscopy, FTIR and transmission electron microscopy (TEM) analyses. The FTIR spectrum showed the integr...

Quercetin, a plant-extracted flavonol, is a potent inhibitor of carbohydrate digestive enzymes. This study aimed to examine: (1) the extent to which quercetin altered the starch digestion and the glycemic potential of the fortified western baked bread as well as oriental steamed bread, (2) the m...

Quercetin is one of the most prominent and widely studied flavonoids. Its oxidation has been previously investigated only indirectly by comparative analyses of structurally analogous compounds, e.g. dihydroquercetin (taxifolin). To provide direct evidence about the mechanism of quercetin oxidati...

Negative primary ions have an advantage for SIMS measurements when positive secondary ions are being observed, because they gain energy from the secondary ion accelerating voltage. Having both Cs+ and I− ions available from the same ion source enables maximum bombarding energy to be obtained for...

Until recently, the number and distribution of cave art sites in the western Indonesian Archipelago has been somewhat limited, hindering our knowledge of the character and development of cave art in the area. However, the recent discovery of seven new cave art sites in the karstic area of Bukit ...

In the last few years, cannabinoid type-2 receptor (CB2R) selective ligands have shown a great potential as novel therapeutic drugs in several diseases. With the aim of discovering new selective cannabinoid ligands, a series of pyridazinone-4-carboxamides was designed and synthesized, and the ne...

A facile and efficient method was developed for the synthesis of 1,2,4,5-tetrahydro-1,4-benzodiazepine-3-ones from 2-chloro-N-(2-nitrobenzyl)acetamides through a reductive cyclization using iron-ammonium chloride in ethanol–water in good yields. This method provides a simple approach to these b...

Experimental infinite dilution activity coefficients, gas-to-liquid partition coefficients and mole fraction solubilities are reported for numerous liquid and solid organic compounds dissolved in 2-methyl-2-butanol at 298.15 K. Experimental values were determined using headspace chromatographic ...

Treatment of germinating sorghum [Sorghum bicolor (L.) Moench] seeds with the grass herbicide, metolachlor (2-chloro-N-[2-ethyl-6-methylphenyl]-N-[2-methoxy-1-methylethyl] acetamide), causes growth retardation, promoted by thickening of the first leaf and thus inhibition of unfolding of secondar...

The aromatic-compound additive in sulfuric acid (H2SO4) was found to promote isobutane/butene alkylation significantly. The selectivity of isooctane (C8) and the alkylate research octane number increased by 23.46% and 5.09, respectively, when thiophene was added to H2SO4, especially. The proport...

The present work investigates the biodegradation of nonisocyanate condensation polyurethanes (NIPU) by aerobic bacterial strains (Achromobacter xylosoxidans G21). The study was conducted on linear and branched polyurethanes prepared from oligoetherol, urea, phenolsulfonic acid, 2-hydroxynaphthal...

Dyeing wool fiber consumes considerable energy and causes contamination, and low-temperature dyeing of wool fiber is a long-standing and often-mentioned topic. The modification of wool fibers and the introduction of novel dyeing processes are common approaches to resolve these issues. In this pa...

The saturated vapor pressures of 4-fluorophthalic anhydride and 4-chlorophthalic anhydride at various temperatures ranging from T = (426 to 560) K, and the isobaric vapor–liquid phase equilibrium data for binary system of 4-fluorophthalic anhydride (1) + 4-chlorophthalic anhydride (2) at pressu...