The preparation of aziridine-2,2-dicarboxylates via 1,4-addition of N,O-bis(trimethylsilyl)hydroxylamine to α,β-unsaturated malonates in the presence of chiral Lewis acids is reported. Good enantioselectivity was observed for conjugate addition catalysed by [Cu(S,S)-Bn-(box)](OTf)2 on isobutyl...

A series of novel N-benzoyl-N’-aryl thiourea derivatives (BTU) bearing different number of alkoxy groups in terminal positions of benzoyl unit and a perfluorooctyl group on the other side have been designed and prepared. Their liquid crystalline properties were investigated by a combination of ...

Quantitative analysis of glycans is an emerging field in glycomic research. Herein we present a rapid and effective dual-labeling strategy, in the combination of isotopic derivatization of N-glycosylamine-based glycans by d0/d5-benzoyl chloride and methylamidation of sialic acids, to relatively ...

In this paper, we have synthesized a series of N-benzoyl-N′-phenyl thiourea derivatives and characterized them by FTIR, elemental analysis, NMR, and X-ray single crystal diffraction. Intermolecular interactions were shown via NH⋯O, NH⋯S, CH⋯O, CH⋯S hydrogen bonds and π⋯π interactions in cryst...

A novel amphipathic chitosan derivative, N-benzoyl-O-acetyl-chitosan (BACS), was prepared by using the selective partial acylation of chitosan (CS), benzoyl chloride, and acetic acid under high-intensity ultrasound. The chemical structure and physical properties of BACS were characterized by FTI...

Five new Cd(II) coordination polymers with N-benzoyl-L-glutamic acid (H2bzgluO) and different N-donor ligands, [Cd(bzgluO)(2,2′-bipy)(H2O)]n (1), [Cd(bzgluO)(2,4′-bipy)2(H2O)·3H2O]n (2), [Cd(bzgluO)(phen)·H2O]n (3), [Cd(bzgluO)(4,4′-bipy)(H2O)]n (4), [Cd(bzgluO)(bpp)(H2O)·2H2O]n (5) were s...

The occurrence of 3D isostructurality in six halogen substituted N-benzoyl-N-phenylbenzamides has been reported and this feature has been quantitatively analyzed in this study. 4-fluoro-N-(4-fluorobenzoyl)N-(fluorphenyl)benzamide (1) was observed to be isostructural with 2-fluoro-N-(2-fluorobenz...

Photoinduced decarboxylative radical additions of 5-membered alicyclic α-amino acids bearing a (2-phenyl)benzoyl protective group to acrylonitrile under mild organic photoredox catalysis conditions furnished γ-amino acid derivatives with high retention of chirality via the memory of chirality ...

Three newly synthesized N‑benzoyl derivatives of isoleucine (3‑methyl 2‑[(4‑methylbenzoyl) amino] pentanoic acid (C-Me(, 2‑(benzoyl amino) 3‑methyl pentanoic acid (C-H) and 2‑[(4‑chlorobenzoyl) amino] 3‑methyl pentanoic acid (C-Cl) were synthesized via Schotten-Baumann method. Afterward, dealing...

The title compound, N-benzoyl-2′-hydroxy-3-methylisovaline, representing synthon polymorphism, can be interesting inter alia from the point of view of modern supramolecular biofunctional materials. A novel crystalline phase (1) was successfully synthesized and its solid-state supramolecular arc...

The oxidative degradation of an azo dye, Acid Red1 (AR1), in aqueous solution using Advanced Oxidation Processes (AOPs), has been investigated. The fast reaction kinetics and the details on the short-lived intermediate radicals from the reaction of hydroxyl radicals (OH) with AR1 were investigat...

Palaeomicrobiology has detected the tuberculosis agent in animal and human skeletons that are thousands of years old. The German doctor Robert Koch was the first microbiologist to report in 1882 the successful isolation of the causative agent of tuberculosis, named 1 year later as Mycobacterium ...

The biological foundations of infectious disease were developed in the 19th century, building on the work of Louis Pasteur. The methodologies of microbiology were greatly advanced by Robert Koch, in Germany, discoverer of tuberculosis, anthrax and cholera organisms and establishing criteria of p...

Since Hayflick’s discovery of cellular senescence (CS), a great volume of knowledge in the field has been accumulated and intensively discussed. Here, we attempted to organize the evidence “for” and “against” the hypothesized causal role of CS in aging. For that purpose, we utilized robust ...

The European red mite, Panonychus ulmi Koch is one of the most important pests in apple orchards and was introduced to Iran by apple seedlings from Europe. The insecticide/acaricide abamectin for example has been used extensively against P. ulmi and some other pests in apple orchards. To evaluat...

Koch carbonylation was carried out using silver trifluoromethanesulfonate (AgOTf). Tertiary alcohols were transformed into the corresponding carboxylic acids in good yield under carbon monoxide atmosphere (5 MPa: initial pressure) at 150°C. It can be assumed that under these reaction conditions...

SummaryRobert Koch's discovery of the anthrax bacillus in 1876 launched the field of medical bacteriology. A ‘golden age’ of scientific discovery ensued. A century after Koch's death, we remember his life and work.

Six natural monoterpenes (1,8-cineole, (-)-citronellal, limonene, α-pinene, pulegone and 4-terpineol) showed high acaricidal activity by fumigant and contact actions against adult females of the two-spotted spider mite, Tetranychus urticae Koch. The monoterpenes exhibited varying degrees of aca...

Koch carbonylation of tertiary alcohol with CO was carried out in decane in the presence of acidic ionic liquid, which presents a novel application of acidic ionic liquid as well as a novel reaction system for Koch reaction that can offer good reusability and easy separation of product. Used as ...

The contents of free salicylic acid and conjugated salicylic acid were determined by using TLC and HPLC at different time after attack by Tetranychus urticae Koch in the first true leaf of frijole (Phaseolus vulgaris. L) plant. A maximal nine fold increase in the free salicylic acid content in t...