Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:636-61-3
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:636-61-3
Min.Order:1 Kilogram
Negotiable
Type:Manufacturers
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:636-61-3
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiry1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards. 2. Now we have established long-term stable r
Cas:636-61-3
Min.Order:1 Kilogram
FOB Price: $1.0 / 2.0
Type:Other
inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
Cas:636-61-3
Min.Order:1 Metric Ton
FOB Price: $1.0 / 3.0
Type:Trading Company
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:636-61-3
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:636-61-3
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:636-61-3
Min.Order:1 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:636-61-3
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:636-61-3
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiryD-Malic acid Specifications Product Name: D-Malic acid sort: Pharmaceutical Intermediates CAS No.: 636-61-3 Formula: C4H6O5 Formul
Cas:636-61-3
Min.Order:5 Metric Ton
FOB Price: $1.0 / 2.0
Type:Other
inquiryHanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr
Cas:636-61-3
Min.Order:1 Kilogram
FOB Price: $200.0 / 400.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:636-61-3
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:636-61-3
Min.Order:1 Kilogram
FOB Price: $41.0 / 56.0
Type:Trading Company
inquiryD(+)-Malic acid CAS:636-61-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat
Cas:636-61-3
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine)
Cas:636-61-3
Min.Order:10 Milligram
Negotiable
Type:Lab/Research institutions
inquiryProduct quality: Our company have high quality product , and also the product we have good manufacture . First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried
Cas:636-61-3
Min.Order:1 Kilogram
FOB Price: $20.0 / 30.0
Type:Trading Company
inquiryPRODUCT DETAILS
Cas:636-61-3
Min.Order:500 Kilogram
FOB Price: $1.0 / 2.0
Type:Lab/Research institutions
inquiryAppearance:white crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Se
Cas:636-61-3
Min.Order:100 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:636-61-3
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and
Cas:636-61-3
Min.Order:1 Gram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:636-61-3
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryHigh Quality D-MALIC ACID/D-APPLE ACID 636-61-3 in stock fast delivery good supplierAppearance:Powder Storage:Dry and ventilated Package:according to customers' requirements Application:APIs Transportation:By air(EMS or EUB or FedEx or TNT ect...) or
Cas:636-61-3
Min.Order:1 Gram
Negotiable
Type:Other
inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:636-61-3
Min.Order:100 Gram
FOB Price: $100.0 / 2000.0
Type:Lab/Research institutions
inquirySuperior quality, moderate price & quick delivery. Appearance:white crystal powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermed
Product name: D-Malic Acid CAS No.: 636-61-3 Molecule Formula:C4H6O5 Molecule Weight:134.09 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TESTING ITEMS
Cas:636-61-3
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryL-Aspartic acid
A
D-Malic acid
B
(2S)-chlorobutanedioic acid
C
2-butenedioic acid
Conditions | Yield |
---|---|
With hydrogenchloride; sodium nitrite In water at -15 - 0℃; for 8h; | A 0.1% B 86% C 0.1% |
With hydrogenchloride; sodium chloride; sodium nitrite In water at -15 - 0℃; for 7h; | A 0.1 - 0.4 %Spectr. B 80% C 0.1% |
(R)-4,4,4-trichloro-3-hydroxybutanoic acid
A
D-Malic acid
B
(2E)-but-2-enedioic acid
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 24h; | A 79% B n/a |
Conditions | Yield |
---|---|
With TETRACYCLINE In water at 37℃; for 18h; Clostridium formicoaceticum, phosphate buffer; | 75% |
biosynthesis by resting cells of Ustilago sphaerogena strain S402; | |
With 2-(cyclohexylamino)ethanesulfonic acid; potassium chloride; potassium hydroxide pH=9; Kinetics; Reagent/catalyst; Enzymatic reaction; |
malic acid-4-methylamide
D-Malic acid
Conditions | Yield |
---|---|
With barium dihydroxide |
Conditions | Yield |
---|---|
With cis-nitrous acid |
Conditions | Yield |
---|---|
With nitrogen oxides; acetic acid at 95℃; |
Conditions | Yield |
---|---|
bei der enzymatischen Spaltung unter dem Einfluss von Hunde- oder Kaninchenmuskelbrei bleibt optisch unreine d(+)-Aepfelsaeure zurueck; | |
With Cinchonin | |
With rac-methylbenzylamine |
chlorosuccinic acid
D-Malic acid
Conditions | Yield |
---|---|
With silver nitrate | |
With silver(l) oxide | |
With water; potassium carbonate; silver nitrate | |
With alkali |
Conditions | Yield |
---|---|
With alkali Hydrolysis.bei der Hydrolyse der Dinatriumsalze; | |
With water Hydrolysis.bei der Hydrolyse der Dinatriumsalze; |
Conditions | Yield |
---|---|
With alkali Hydrolysis.bei der Hydrolyse der Kupfer(II)-salze; | |
With water Hydrolysis.bei der Hydrolyse der Kupfer(II)-salze; | |
Hydrolysis.in saurer oder anfangs neutraler Loesung; |
iodo-succinic acid
D-Malic acid
Conditions | Yield |
---|---|
With ammonia |
Conditions | Yield |
---|---|
With cis-nitrous acid |
(R)-(+)-2-acetoxysuccinic anhydride
D-Malic acid
Conditions | Yield |
---|---|
With sodium hydroxide Ambient temperature; |
D-Malic acid
Conditions | Yield |
---|---|
With potassium hydroxide; sodium periodate; ozone 1.) H2O, 16 h, room temperature, 2.) HOAc-HCOOH (9:1) 10 deg C, 110 deg C, 12 h, 3.) H2O, 30 min; Multistep reaction; |
D-Malic acid
Conditions | Yield |
---|---|
With sodium hydroxide for 48h; Heating; |
D-Malic acid
Conditions | Yield |
---|---|
In methanol at 10℃; Yield given; |
D-Malic acid
Conditions | Yield |
---|---|
In water at 10℃; Yield given; |
Conditions | Yield |
---|---|
at 45 - 50℃; lactone of/the/ dextrorotatory α.γ-dioxy-butyric acid; |
hydrogenchloride
methanol
(2S,3S)-2-Acetoxy-3-chlor-bernsteinsaeuredimethylester
D-Malic acid
Conditions | Yield |
---|---|
nachfolgenden Reduktion mit einem mit Platindraht umwickelten Zinkstab in Wasser.Hydrolysis; |
Conditions | Yield |
---|---|
at 45 - 50℃; |
Conditions | Yield |
---|---|
beim Verseifen des Reaktionsprodukts; levorotatory bromo-succinic acid; |
Conditions | Yield |
---|---|
Dinatriumsalz reagiert; l(-)-chlorosuccinic acid; |
D-Malic acid
Conditions | Yield |
---|---|
Hydrolysis; |
D-Malic acid
Conditions | Yield |
---|---|
Verseifung; |
Conditions | Yield |
---|---|
With thionyl chloride | 100% |
Stage #1: methanol With acetyl chloride at 0℃; for 1h; Stage #2: D-Malic acid at 20℃; for 16h; | 100% |
With thionyl chloride at 0 - 20℃; Inert atmosphere; | 99% |
D-Malic acid
(R)-1,2,4-butanetriol
Conditions | Yield |
---|---|
With Trimethyl borate; dimethylsulfide borane complex In tetrahydrofuran Inert atmosphere; | 100% |
With Trimethyl borate; dimethylsulfide borane complex In tetrahydrofuran for 20h; Ambient temperature; | 98% |
With Trimethyl borate; dimethylsulfide borane complex In tetrahydrofuran at 0 - 20℃; | 97% |
D-Malic acid
trifluoroacetic anhydride
(R)-2,5-dioxotetrahydrofuran-3-yl 2,2,2-trifluoroacetate
Conditions | Yield |
---|---|
at 20℃; for 4h; Cooling with ice; Inert atmosphere; | 100% |
at 0℃; for 2h; | |
for 2h; Ambient temperature; | |
at 0 - 20℃; for 3h; | |
for 2h; |
Conditions | Yield |
---|---|
With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine | 100% |
With N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine In acetonitrile Esterification; |
D-Malic acid
acetyl chloride
(R)-(+)-2-acetoxysuccinic anhydride
Conditions | Yield |
---|---|
at 45℃; for 6h; | 100% |
at 45℃; for 6h; | 90% |
at 45℃; for 6h; | 90% |
bortezomib
D-Malic acid
2-((R)-2-((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)-5-oxo-1,3,2-dioxaborolan-4-yl)acetic acid
Conditions | Yield |
---|---|
In acetone at 25℃; Heating; | 100% |
D-Malic acid
methanesulfonyl chloride
(S)-methane-sulphonyloxysuccinic Acid
Conditions | Yield |
---|---|
In tetrahydrofuran for 10h; Heating / reflux; | 99% |
Conditions | Yield |
---|---|
In water malic acid dissolved in H2O, treated with boric acid, aq. NaOH added, stirred in open flask at 100 °C for ca. 4 h; mixt. evapd.; detd. by NMR, XRD; | 99% |
D-Malic acid
(R,Z)-2-(5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-5-(2-hydroxy-3-morpholin-4-ylpropyl)-3-methyl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one
Conditions | Yield |
---|---|
In methanol; water at 20 - 50℃; Darkness; | 99% |
Conditions | Yield |
---|---|
Stage #1: D-Malic acid With trifluoroacetic acid at 20℃; for 0.666667h; Inert atmosphere; Stage #2: methanol at 20℃; for 1.5h; Inert atmosphere; | 99% |
Stage #1: D-Malic acid With trifluoroacetic anhydride for 0.666667h; Stage #2: methanol at 20℃; for 1.5h; | 84% |
Stage #1: D-Malic acid With trifluoroacetic anhydride at 20℃; for 3h; Stage #2: methanol at 20℃; |
Conditions | Yield |
---|---|
In water at 95℃; | 99% |
D-Malic acid
pivalaldehyde
2-((2R, 4R)-2-tert-butyl-5-oxo-1,3-dioxolan-4-yl) acetic acid
Conditions | Yield |
---|---|
With sulfuric acid; toluene-4-sulfonic acid In pentane for 36h; Heating; | 98% |
With sulfuric acid; toluene-4-sulfonic acid In pentane for 6h; Heating; | 92% |
Stage #1: D-Malic acid With chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane In dichloromethane at 23℃; Inert atmosphere; Stage #2: pivalaldehyde With trimethylsilyl trifluoromethanesulfonate In dichloromethane at -25℃; Inert atmosphere; | 82% |
D-Malic acid
cyclohexanone
2-[(4R)-2-cyclohexylidene-5-oxo-1,3-dioxolan-4-yl]acetic acid
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In diethyl ether at 0 - 20℃; for 19h; | 98% |
With boron trifluoride diethyl etherate In diethyl ether at 0 - 20℃; for 25h; | 93% |
With boron trifluoride diethyl etherate In diethyl ether at 0 - 20℃; for 25h; | |
With boron trifluoride diethyl etherate In diethyl ether at 0 - 20℃; for 20h; | |
Stage #1: D-Malic acid; cyclohexanone With boron trifluoride diethyl etherate In diethyl ether at 0 - 20℃; for 97h; Stage #2: With water; sodium acetate In diethyl ether for 2h; |
Conditions | Yield |
---|---|
With thionyl chloride Esterification; | 97% |
With thionyl chloride for 7h; Reflux; | 95% |
With sulfuric acid at 90℃; for 12h; Inert atmosphere; | 95% |
D-Malic acid
2,2-dimethoxy-propane
2-[(4R)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]acetic acid
Conditions | Yield |
---|---|
With pyridinium p-toluenesulfonate at 25℃; | 97% |
With pyridinium p-toluenesulfonate for 48h; Ambient temperature; | 96% |
With toluene-4-sulfonic acid In dichloromethane for 4h; Ambient temperature; | 90% |
Conditions | Yield |
---|---|
In methanol; dichloromethane at 20℃; for 8h; | 97% |
Conditions | Yield |
---|---|
With 8-aminopyrene-1,3,6-trisulfonic acid, trisodium salt | 95% |
With toluene-4-sulfonic acid In toluene Heating; | 95% |
Conditions | Yield |
---|---|
With sulfuric acid at 20℃; for 3h; | 95% |
Conditions | Yield |
---|---|
In ethanol at 20℃; for 69h; | 95% |
Conditions | Yield |
---|---|
In methanol at 15 - 45℃; | 93.51% |
D-Malic acid
5-bromo-3-(N,N-dimethylaminomethyl)-N-methylindole
Conditions | Yield |
---|---|
In methanol for 2h; Reflux; | 93% |
Conditions | Yield |
---|---|
With trifluoroacetic anhydride Inert atmosphere; | 92% |
Stage #1: D-Malic acid With trifluoroacetic anhydride at 0℃; Stage #2: benzyl alcohol at 20℃; Further stages.; | 86% |
Stage #1: D-Malic acid With trifluoroacetic anhydride at 0℃; for 2.5h; Stage #2: benzyl alcohol at 20℃; for 2h; | |
Stage #1: D-Malic acid With trifluoroacetic anhydride at 20℃; for 4h; Cooling; Stage #2: benzyl alcohol | 28 g |
tricarbonyl(cycloheptatriene)molybdenum(0)
D-Malic acid
Conditions | Yield |
---|---|
In methanol (N2); Schlenk technique; soln. of Et4OH in MeOH was added dropwise with stirring to soln. of acid in MeOH at room temp.; solvent was removed (vac.); dissolved in MeOH; obtained soln. was added to soln. of Mo complex in MeOH; mixt. was stirred overnight; solvent removed (vac.); extd. (MeCN/MeOH); layered with ether; elem. anal.; | 90% |
D-Malic acid
4-methoxy-benzylamine
(R)-3-hydroxy-1-(4-methoxybenzyl)pyrrolidine-2,5-dione
Conditions | Yield |
---|---|
In 5,5-dimethyl-1,3-cyclohexadiene for 8h; Reflux; optical yield given as %ee; | 90% |
In m-xylene Reflux; | 78% |
D-Malic acid
(R)-(+)-2-(2,5-difluorophenyl)pyrrolidine
Conditions | Yield |
---|---|
With triethylamine In ethanol at 20 - 65℃; Inert atmosphere; | 90% |
D-Malic acid
eszopiclone
(S)-(+)-6-(5-chloro-2-pyridinyl)-7-(4-methylpiperazin-1-yl-carbonyloxy)-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine-5-one D-(+)-malate
Conditions | Yield |
---|---|
In ethyl acetate for 18h; | 89% |
Conditions | Yield |
---|---|
With salicylaldehyde at 80℃; for 14h; Inert atmosphere; chemoselective reaction; | 89% |
D-Malic acid
zopiclon
(S)-(+)-6-(5-chloro-2-pyridinyl)-7-(4-methylpiperazin-1-yl-carbonyloxy)-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine-5-one D-(+)-malate
Conditions | Yield |
---|---|
In methanol; acetone at 10 - 48℃; for 4h; | 88% |
In methanol; acetone at 55 - 56℃; for 0.5h; Product distribution / selectivity; | 41% |
Conditions | Yield |
---|---|
With hydrogenchloride; sodium borohydrid; lithium chloride In tetrahydrofuran; methanol | 88% |
Conditions | Yield |
---|---|
Stage #1: D-Malic acid; acetyl chloride for 20h; Reflux; Stage #2: 4-methoxy-benzylamine In tetrahydrofuran at 0 - 25℃; for 18h; | 87% |
Stage #1: D-Malic acid; acetyl chloride Reflux; Stage #2: 4-methoxy-benzylamine With acetyl chloride In dichloromethane Reflux; Stage #3: With acetyl chloride In dichloromethane Reflux; | |
Stage #1: D-Malic acid; acetyl chloride for 16h; Reflux; Stage #2: 4-methoxy-benzylamine In tetrahydrofuran at 20℃; for 18h; Stage #3: acetyl chloride for 18h; Reflux; | 660 mg |
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