2-Bromopropane supplier | CasNO.75-26-3

Name
2-Bromopropane
EINECS 200-855-1
CAS No. 75-26-3
Article Data132
CAS DataBase
Density 1.342 g/cm³
Solubility 0.3 g/100 mL in water
Melting Point -89 °C
Formula C₃H₇Br
Boiling Point 60.6 °C at 760 mmHg
Molecular Weight 122.993
Flash Point 19.4 °C
Transport Information UN 2344 3/PG 2
Appearance Colorless transparent liquid
Safety 53-16-45
Risk Codes 60-11-48/20-66
Molecular Structure
Hazard Symbols F,T
Synonyms Isopropyl bromide;Propane, 2-bromo-;
PSA 0.00000
LogP 1.78970

Synthetic route

: 187737-37-7
propene

A: 106-94-5
propyl bromide

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With hydrogen bromide; oxygen at 20 - 23℃; under 1551.49 - 1603.2 Torr; for 4.5h;	A 97.8% B 1.57%

: 74-98-6
propane

: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With 2AlBr3*CBr4; bromine at -20℃; for 3h;	96%
With antimony pentafluoride; 1,2-dibromomethane 1.) -78 deg C, 2 h, 2.) RT, 24 h;	64%
With 2AlBr3*CBr4; bromine In various solvent(s) at -20℃; for 3h;	48 % Turnov.

: 67-63-0
isopropyl alcohol

: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With carbon tetrabromide; sodium bromide In N,N-dimethyl-formamide for 3h; Catalytic behavior; Irradiation;	93%
With tetralin; bromine ueber mehrere Stufen;
With sulfuric acid; potassium bromide

: 116-17-6
triisopropyl phosphite

: 99-90-1
para-bromoacetophenone

A: 106052-23-7
diisopropyl [4-(acetyl)phenyl]phosphonate

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With nickel dichloride at 180 - 190℃; for 0.0833333h;	A 91% B n/a

...Expand

: 108-20-3
di-isopropyl ether

: 201230-82-2
carbon monoxide

: 104-81-4
4-Methylbenzyl bromide

A: 64450-64-2
isopropyl 2-p-tolylacetate

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
1,5-hexadienerhodium(I)-chloride dimer; potassium iodide at 75 - 90℃; under 735.5 Torr; overnight or in n-heptane;	A 78% B n/a

...Expand

: 116670-01-0
{(η5-C5Me5)Os(CO)(PMe2Ph)i-Pr}

: 7726-95-6
bromine

A: 107087-80-9
{(η5-C5Me5)Os(CO)(PMe2Ph)Br}

B: 187737-37-7
propene

C: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
In dichloromethane-d2 (N2); electrophilic cleavage reaction by addn. of bromine to a soln. of Cp*Os(CO)(PMe2Ph)i-Pr in CD2Cl2;; not isolated, detected by NMR;;	A 77% B 9% C 50%

...Expand

: 116669-98-8
{(η5-C5Me5)Os(CO)2i-Pr}

: mercury dibromide

A: 81554-89-4
{(η5-C5Me5)Os(CO)2Br}

B: 18819-83-5
isopropylmercury (1+); bromide

C: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
In dichloromethane-d2 (N2); electrophilic cleavage reaction by addn. of HgBr2 to a soln. of Cp*Os(CO)2i-Pr in CD2Cl2;; not isolated, detected by NMR;;	A 77% B 61% C 11%

...Expand

: 116-17-6
triisopropyl phosphite

: 2142-63-4
1-(3-Bromophenyl)ethanone

A: 127099-70-1
(3-Acetyl-phenyl)-phosphonic acid diisopropyl ester

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With nickel dichloride at 180 - 190℃; for 0.0833333h;	A 76% B n/a

...Expand

: 116669-98-8
{(η5-C5Me5)Os(CO)2i-Pr}

: 7726-95-6
bromine

A: 81554-89-4
{(η5-C5Me5)Os(CO)2Br}

B: 187737-37-7
propene

C: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
In dichloromethane-d2 (N2); electrophilic cleavage reaction by addn. of bromine to a soln. of Cp*Os(CO)2i-Pr in CD2Cl2;; not isolated, detected by NMR;;	A 75% B 6% C 39%

...Expand

: 76313-88-7
2-isopropyl-2-boraadamantane

A: 76313-91-2
2-bromo-2-boraadamantane

B: 3α-bromo-7α-[(2-propyl)bromoboryl]bicyclo[3.3.1]nonane

C: 4-ethoxy-5,5-dimethyl-4-borahomoadamantane

D: 10035-10-6, 12258-64-9
hydrogen bromide

E: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With ethanol; bromine In dichloromethane Irradiation (UV/VIS); under Ar, to soln. of educt in CH2Cl2 added soln. of Br2 in CH2Cl2 in portions during 1 h at -10°C under pressure of 170-200 mmHg with irrdn. with 200 W bulb, stirred for 30 min at -10°C, heated under vac. to 17°C; concd. in vac., cooled to -70°C, ethanol added, evapd. in vac. without heating; GLC anal. of products after oxidative hydrolysis;	A n/a B n/a C n/a D 73% E 4%
With ethanol; bromine In dichloromethane under Ar in the dark, to soln. of educt in CH2Cl2 added soln. of Br2 inCH2Cl2 in portions during 5.5 h at -10°C under pressure of 170-200 mmHg, stirred for 30 min at -10°C, heated under vac. to 17°C; concd. in vac., cooled to -70°C, ethanol added, evapd. in vac. without heating; GLC anal. of products after oxidative hydrolysis;	A n/a B n/a C n/a D 14% E 65%
With ethanol; bromine In dichloromethane under Ar, to soln. of educt in CH2Cl2 added soln. of Br2 in CH2Cl2 in portions during 2.5 h at -10°C under pressure of 170-200 mmHg, stirred for 30 min at -10°C, heated under vac. to 17°C; concd. in vac., cooled to -70°C, ethanol added, evapd. in vac. without heating; GLC anal. of products after oxidative hydrolysis;	A n/a B n/a C n/a D 23% E 38%

...Expand

: 116-17-6
triisopropyl phosphite

: 109-70-6
1,3-chlorobromopropane

A: 63602-20-0
O,O-diisopropyl (3-chloropropyl)phosphonate

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
at 135 - 140℃; for 3h; Arbuzov rearrangement;	A 28% B 68%

...Expand

: 104-92-7
1-bromo-4-methoxy-benzene

: 116-17-6
triisopropyl phosphite

A: 106052-22-6
diisopropyl (4-methoxyphenyl)phosphonate

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With nickel dichloride at 185 - 195℃; for 0.0833333h;	A 67% B n/a

...Expand

: 108-86-1
bromobenzene

: 116-17-6
triisopropyl phosphite

A: 7237-16-3
diisopropyl phenylphosphonate

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With nickel dichloride at 185 - 195℃; for 0.0833333h;	A 65.5% B n/a

...Expand

: 1638-86-4
diethyl phenylphosphonite

: 109-70-6
1,3-chlorobromopropane

A: 75-26-3
isopropyl bromide

B: 231610-93-8
ethyl (3-chloropropyl)phenylphosphinate

Conditions

Conditions	Yield
at 135 - 140℃; for 3h; Arbuzov rearrangement;	A n/a B 62%

...Expand

: 116-17-6
triisopropyl phosphite

: 578-57-4
2-bromoanisole

A: 127099-69-8
(2-Methoxy-phenyl)-phosphonic acid diisopropyl ester

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With nickel dichloride at 190 - 200℃; for 0.0833333h;	A 61% B n/a
nickel dichloride at 190 - 200℃;

...Expand

: 116-17-6
triisopropyl phosphite

: 1122-91-4
4-bromo-benzaldehyde

A: 127099-71-2
4-(diisopropoxyphosphoryl)benzaldehyde

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With nickel dichloride at 170 - 180℃; for 0.0833333h;	A 54% B n/a

...Expand

: 106-94-5
propyl bromide

: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
at 250 - 270℃; Equilibrium constant;
at 250 - 270℃; Equilibrium constant; die Umlagerung wird durch Sauerstoff, HBr, HgBr2, Tetraaethylammoniumbromid und Dibutylamin beschleunigt;
lagert sich im UV-Licht teilweise um;

: 75-30-9
2-iodo-propane

: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With bromine
With hydrogen bromide
With pyridine; tributyltin bromide at 125℃; Thermodynamic data; Equilibrium constant; Δ G;	49 % Chromat.

: 187737-37-7
propene

: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With hydrogen bromide bei Ausschluss von Luft und Zusatz von Oxydationsverzoegern wie Diphenylamin oder Thiokresol;
With tetrachloromethane; hydrogen bromide
With hydrogen bromide; iron(III) chloride im Dunkeln;

: 78-75-1
1,2-Dibromopropane

: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With hydrogen iodide at 150℃;

: 74-98-6
propane

A: 78-75-1
1,2-Dibromopropane

B: 106-94-5
propyl bromide

C: 109-64-8
1,3-dibromo-propane

D: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
at 300 - 330℃; Bromierung; weitere Produkte: 2.2-Dibrom-propan, Tribrompropan und Tetrabrompropan;

...Expand

: 74-98-6
propane

A: 106-94-5
propyl bromide

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With bromine at 300 - 330℃;
With Bromoform; 1,2-dibromomethane In nitrogen at 525℃; for 0.0166667h;

: 596-43-0
bromo-triphenyl-methane

: 2959-75-3
isopropyl-diphenyl-phosphine oxide

A: diphenyl-trityl-phosphine oxide

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
at 100 - 200℃;

...Expand

: 596-43-0
bromo-triphenyl-methane

: 27350-46-5
isopropyl diphenylphosphinite

A: diphenyl-trityl-phosphine oxide

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
at 100 - 200℃;

...Expand

: 67-63-0
isopropyl alcohol

A: 3770-98-7
1,1,1-tribromopropan-2-one

B: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With bromine

: 2307-69-9
toluene-4-sulfonic acid isopropyl ester

: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With tetrabutylammomium bromide In acetone at 50℃; Kinetics; other reaction partners, other solvents, other temperatures;

: 2025-55-0
isopropyl radical

: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With bromine at 24.9℃; Kinetics; other temperatures;

: 187737-37-7
propene

A: 4283-80-1
2-bromo-2-methylpentane

B: 106-94-5
propyl bromide

C: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With hydrogen bromide at -78℃; for 96h; Product distribution;	A 34 % Chromat. B 0.5 % Chromat. C 45 % Chromat.
With hydrogen bromide at -78℃; for 96h;	A 34 % Chromat. B 0.5 % Chromat. C 45 % Chromat.

...Expand

: 75-29-6
isopropyl chloride

: 75-26-3
isopropyl bromide

Conditions

Conditions	Yield
With tributyltin bromide In pyridine at 50℃; Thermodynamic data; Equilibrium constant; other temperatures, Δ G;

: 100-83-4
meta-hydroxybenzaldehyde

: 75-26-3
isopropyl bromide

: 75792-33-5
3-isopropoxybenzaldehyde

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide	100%
With potassium carbonate In N,N-dimethyl-formamide at 70℃;	90%
In acetone	88%

: 621-59-0
isovanillin

: 75-26-3
isopropyl bromide

: 34123-66-5
O-isopropylisovanillin

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 48h; Inert atmosphere;	100%
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 1h;	100%
With potassium carbonate In dimethyl sulfoxide at 55℃; for 11h; Inert atmosphere;	100%

: 16532-79-9
4-Bromophenylacetonitrile

: 75-26-3
isopropyl bromide

: 51632-12-3
2-(4-bromophenyl)-3-methylbutanenitrile

Conditions

Conditions	Yield
Stage #1: 4-Bromophenylacetonitrile With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; Inert atmosphere; Stage #2: isopropyl bromide In N,N-dimethyl-formamide; mineral oil for 16h; Inert atmosphere; Heating;	100%
Stage #1: 4-Bromophenylacetonitrile With sodium hydride In N,N-dimethyl-formamide; mineral oil for 0.25h; Stage #2: isopropyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 2h;
Stage #1: 4-Bromophenylacetonitrile With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.25h; Stage #2: isopropyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 2h;	21.3 g
Stage #1: 4-Bromophenylacetonitrile With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere; Stage #2: isopropyl bromide In tetrahydrofuran for 16h; Inert atmosphere;
With sodium hydride

: 121-33-5
vanillin

: 75-26-3
isopropyl bromide

: 2538-98-9
4-isopropyloxy-3-methoxybenzaldehyde

Conditions

Conditions	Yield
	100%
With potassium carbonate In N,N-dimethyl-formamide at 18℃; for 19h;	100%
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 1h;	100%

: 1666-13-3
diphenyl diselenide

: 75-26-3
isopropyl bromide

: 22233-89-2
(phenylseleno)-2-propane

Conditions

Conditions	Yield
With sodium tetrahydroborate In 1,2-dimethoxyethane at 20℃; for 12h; Inert atmosphere;	100%
With indium iodide In dichloromethane at 20℃; for 1h;	80%
With N,N,N,N,N,N-hexamethylphosphoric triamide; samarium diiodide In tetrahydrofuran for 3h; Heating;	78%
With triphenylphosphine; 1-pentyl-3-methylimidazolium bromide at 75℃; for 6h;	72%

: 15288-02-5
6-hydroxy-7-methoxy-1-tetralone

: 75-26-3
isopropyl bromide

: 98799-45-2
6-isopropoxy-7-methoxy-1-tetralone

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide Heating;	100%

: 3753-27-3
sodium 4-methylbenzenesulfonothioate

: 75-26-3
isopropyl bromide

: 53291-31-9
4-Methylbenzolthiosulfonsaeure-S-isopropylester

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere;	100%
With Amberlyst A-26 (Cl(1-) form) 1.) H2O, r.t., 18 h; 2.) benzene, reflux, 25 h; Yield given. Multistep reaction;

: 75-26-3
isopropyl bromide

: 638-21-1
phenylphosphane

: 54722-12-2
isopropyl(phenyl)phosphine

Conditions

Conditions	Yield
With sodium bis(2-methoxyethoxy)aluminium dihydride In tetrahydrofuran at 65℃; for 6h;	100%
With potassium hydroxide 1.) DMSO, 2.) 50 - 60 deg C, 1 h; Yield given. Multistep reaction;
With potassium hydroxide 1) DMSO, 20 deg C, 2) DMSO, 50-60 deg C, 1.0 h; Yield given. Multistep reaction;

: 14371-10-9
(E)-3-phenylpropenal

: 591-51-5
phenyllithium

: 75-26-3
isopropyl bromide

: 85267-90-9
(+/-)-4-methyl-1,3-diphenylpentan-1-one

Conditions

Conditions	Yield
Stage #1: (E)-3-phenylpropenal; phenyllithium In tetrahydrofuran at 20℃; for 7h; Stage #2: isopropyl bromide In tetrahydrofuran Further stages.;	100%
Stage #1: (E)-3-phenylpropenal; phenyllithium In tetrahydrofuran at 20℃; for 7h; Addition; Stage #2: isopropyl bromide In tetrahydrofuran at 20℃; Alkylation;	100 % Chromat.

...Expand

: 75-26-3
isopropyl bromide

: 75-08-1
ethanethiol

: 5145-99-3
ethyl isopropyl sulfide

Conditions

Conditions	Yield
Stage #1: ethanethiol With sodium tetrahydroborate; sodium hydroxide In water at 5℃; Inert atmosphere; Stage #2: isopropyl bromide; tetrabutylammomium bromide In water at 50℃; Inert atmosphere;	100%
With potassium hydroxide In ethanol for 0.5h; Heating;	51%

: 148-53-8
3-methoxy-2-hydroxybenzaldehyde

: 75-26-3
isopropyl bromide

: 75792-35-7
2-isopropoxy-3-methoxy-benzaldehyde

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20 - 110℃; Industry scale; Inert atmosphere;	100%
With potassium carbonate In N,N-dimethyl-formamide at 110℃;	99%
Stage #1: 3-methoxy-2-hydroxybenzaldehyde With tetrabutylammomium bromide; potassium carbonate In acetone at 20℃; for 0.25h; Stage #2: isopropyl bromide In acetone at 20℃; for 24h;	96%

: 16611-84-0
6-Pentadecylsalicylic Acid

: 75-26-3
isopropyl bromide

: 440094-90-6
isopropyl-2-isopropoxy-6-pentadecylbenzoate

Conditions

Conditions	Yield
With tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate In 4-methyl-2-pentanone for 24h; Reflux;	100%
With potassium carbonate In various solvent(s) for 36h; Heating;
With benzyltri(n-butyl)ammonium chloride; potassium carbonate In 4-methyl-2-pentanone for 8h; Heating / reflux;
With benzyltri(n-butyl)ammonium chloride; potassium carbonate In 4-methyl-2-pentanone for 8h; Heating / reflux;

: 304-06-3
3-phenylsalicylic acid

: 75-26-3
isopropyl bromide

: 566162-84-3
2-isopropoxy-biphenyl-3-carboxylic acid isopropyl ester

Conditions

Conditions	Yield
With potassium carbonate at 50℃; for 12h;	100%

: 118-93-4
o-hydroxyacetophenone

: 75-26-3
isopropyl bromide

: 70201-54-6
1-(2-(1-methylethoxy)phenyl)ethanone

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 3h; Inert atmosphere;	100%
With potassium carbonate In N,N-dimethyl-formamide at 70℃;	94%
With potassium carbonate; potassium iodide In acetone Heating;	91%

: 75-26-3
isopropyl bromide

: 178626-86-3
2,3-dimercaptobenzoic acid methyl ester

: 547765-68-4
2,3-bis-isopropylsulfanyl-benzoic acid methyl ester

Conditions

Conditions	Yield
With lithium methanolate In methanol for 20h; Heating;	100%

: 7368-78-7
4-bromoguaiacol

: 75-26-3
isopropyl bromide

: 138505-27-8
4-bromo-1-isopropoxy-2-methoxy-benzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20 - 90℃;	100%
With potassium carbonate In dimethyl sulfoxide at 20 - 55℃; for 2h;	94%
With potassium carbonate In dimethyl sulfoxide at 55℃; for 2h;	84%

: 73751-11-8
ethyl 5-bromo-4-hydroxy-3-methylbenzofuran-2-carboxylate

: 75-26-3
isopropyl bromide

: 857081-69-7
ethyl 5-bromo-4-isopropoxy-3-methyl-1-benzofuran-2-carboxylate

Conditions

Conditions	Yield
With potassium carbonate; bis-triphenylphosphine-palladium(II) chloride In N,N-dimethyl-formamide at 20℃; for 12h;	100%

: 2973-76-4
5-bromo-4-hydroxy-3-methoxybenzaldehyde

: 75-26-3
isopropyl bromide

: 400070-31-7
3-bromo-4-isopropyloxy-5-methoxybenzaldehyde

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 80℃;	100%

: 898830-67-6
2,2'-dihydroxybiphenyl-3,3'-dicarboxylic acid bisdiethyl amide

: 75-26-3
isopropyl bromide

: 898830-75-6
2,2'-diisopropoxy-biphenyl-3,3'-dicarboxylic acid bis-diethylamide

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide	100%

: 99-76-3
methyl 4-hydroxylbenzoate

: 75-26-3
isopropyl bromide

: 35826-59-6
methyl 4-isopropoxybenzoate

Conditions

Conditions	Yield
With potassium carbonate In acetone for 72h; Inert atmosphere; Reflux;	100%
With potassium carbonate In acetone for 72h; Inert atmosphere; Reflux;	100%
With potassium carbonate In acetone at 85℃; for 72h; Sealed tube;	94.7%
With sodium hydride In N,N-dimethyl-formamide at 60℃;	80%

: 124702-80-3
5,6-dihydroxy-indan-1-one

: 75-26-3
isopropyl bromide

: 760995-28-6
5,6-diisopropoxyindan-1-one

Conditions

Conditions	Yield
With caesium carbonate In DMF (N,N-dimethyl-formamide) at 60℃; for 8h;	100%

: 3470-49-3
5-hydroxy-2,3-dihydro-1H-indene-1-one

: 75-26-3
isopropyl bromide

: 760995-38-8
5-isopropoxyindan-1-one

Conditions

Conditions	Yield
With caesium carbonate In DMF (N,N-dimethyl-formamide) at 60℃;	100%

: 127724-13-4
methyl 4-hydroxybenzofuran-2-carboxylate

: 75-26-3
isopropyl bromide

: 857080-64-9
methyl 4-isopropoxy-1-benzofuran-2-carboxylate

Conditions

Conditions	Yield
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 20℃;	100%

: 99246-81-8
5-chloro-4-hydroxy-3-methyl-benzofuran-2-carboxylic acid ethyl ester

: 75-26-3
isopropyl bromide

: 857080-97-8
5-chloro-4-isopropoxy-3-methyl-benzofuran-2-carboxylic acid ethyl ester

Conditions

Conditions	Yield
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 20℃;	100%

: 1092447-34-1
2-(3,5-dichloro-2-hydroxy-benzenesulfonylamino)-indan-2-carboxylic acid ethyl ester

: 75-26-3
isopropyl bromide

: 1092447-35-2
2-(3,5-dichloro-2-isopropoxy-benzenesulfonylamino)-indan-2-carboxylic acid ethyl ester

Conditions

Conditions	Yield
With caesium carbonate; potassium iodide In N,N-dimethyl-formamide at 110℃; for 2.5h; Microwave irradiation;	100%

: 55717-45-8
6-bromo-pyridin-3-ol

: 75-26-3
isopropyl bromide

: 857992-23-5
2-bromo-5-isopropoxypyridine

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 2h;	100%
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 2h;

: 6358-06-1
5-amino-2-chlorophenol

: 75-26-3
isopropyl bromide

: 76464-54-5
4-chloro-3-isopropoxyaniline

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile Reflux;	100%
With potassium carbonate In acetonitrile at 20℃; for 24h; Reflux;	87%
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 2.5h;	58%
With potassium carbonate In acetonitrile at 80℃; for 16h;	47%

: 1072-63-5
1-vinylimidazole

: 75-26-3
isopropyl bromide

: 1020109-60-7
1-vinyl-3-isopropylimidazolium bromide

Conditions

Conditions	Yield
for 16h; Reflux;	100%

: 5010-37-7
2-(4-bromo-phenyl)-5-hydroxy-benzofuran-3-carboxylic acid ethyl ester

: 75-26-3
isopropyl bromide

: 691856-79-8
ethyl 2-(4-bromophenyl)-5-isopropoxybenzofuran-3-carboxylate

Conditions

Conditions	Yield
With caesium carbonate In 1-methyl-pyrrolidin-2-one at 60℃; for 4h;	100%
Stage #1: 2-(4-bromo-phenyl)-5-hydroxy-benzofuran-3-carboxylic acid ethyl ester With caesium carbonate In 1-methyl-pyrrolidin-2-one at 20℃; for 0.333333h; Stage #2: isopropyl bromide In 1-methyl-pyrrolidin-2-one at 80℃; for 4h;	95%

: 6320-01-0
3-Bromothiophenol

: 75-26-3
isopropyl bromide

: 70398-87-7
1-bromo-3-isopropylsulfanylbenzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;	100%
With potassium carbonate In acetonitrile for 2h; Reflux;	72%
With potassium carbonate In acetone for 18h; Inert atmosphere; Reflux;

2-Bromopropane Consensus Reports

Reported in EPA TSCA Inventory.

2-Bromopropane Standards and Recommendations

DOT Classification: 3; Label: Flammable Liquid

2-Bromopropane Analytical Methods

2-Bromopropane (CAS NO.75-26-3) is may be prepared in the ordinary manner of alkyl bromides, by reacting isopropanol with phosphorus and bromine, or with phosphorus tribromide.

2-Bromopropane Specification

1. Introduction of 2-Bromopropane
2-Bromopropane, its cas register number is 75-26-3. It also can be called Isopropyl bromide; Propane, 2-bromo-; 2-Isothiocyanatopropane. It is a colourless liquid.
2-Bromopropane is a colorless liquid. It is used for introducing the isopropyl functional group in organic synthesis.

2. Properties of 2-Bromopropane
XLogP3-AA: 1.8
EINECS: 200-855-1
Melting Point: -89 °C
Surface Tension: 23.1 dyne/cm
Density: 1.342 g/cm³
Flash Point: 19.4 °C
Enthalpy of Vaporization: 28.33 kJ/mol
Boiling Point: 60.6 °C at 760 mmHg
Vapour Pressure: 205 mmHg at 25°C
Refractive index: n20/D 1.425(lit.)
Storage temp.: Flammables area
Water Solubility: 0.3 g/100 mL
Stability: Stable. Flammable. Incompatible with strong oxidizing agents.
Product Categories: Organics

3. Toxicity of 2-Bromopropane

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mammal (species unspecified)	LC50	inhalation	36gm/m³ (36000mg/^m3)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(4), Pg. 55, 1974.
mouse	LC50	inhalation	31171ppm/4H (31171ppm)	BEHAVIORAL: AGGRESSION	Industrial Health. Vol. 34, Pg. 403, 1996.
mouse	LD50	intraperitoneal	4837mg/kg (4837mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 20(12), Pg. 52, 1976.

4. Safety Information of 2-Bromopropane
Moderately toxic by intraperitoneal route. A very flammable liquid and dangerous fire hazard. When heated to decomposition it emits toxic fumes of Br⁻. See also BROMIDES.
Hazard Codes:

T
The Risk Statements information of 2-Bromopropane:
11: Highly Flammable
60: May impair fertility
66: Repeated exposure may cause skin dryness or cracking
48/20: Harmful: danger of serious damage to health by prolonged exposure through inhalation
The Safety Statements information:
16: Keep away from sources of ignition - No smoking
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53: Avoid exposure - obtain special instruction before use
RIDADR: UN 2344 3/PG 2
WGK Germany: 1
RTECS: TX4111000
HazardClass: 3
PackingGroup: II
HS Code: 29033036

5. Use of 2-Bromopropane
2-Bromopropane can be used in the synthesis of pharmaceuticals, dyes and other organics.

Product Name

2-Bromopropane

Synthetic route

2-Bromopropane Consensus Reports

2-Bromopropane Standards and Recommendations

2-Bromopropane Analytical Methods

2-Bromopropane Specification

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