4-Hydrazinobenzenesulfonic acid supplier

Name
4-Hydrazinobenzenesulfonic acid
EINECS 202-694-2
CAS No. 98-71-5
Article Data35
CAS DataBase
Density 1.583g/cm³
Solubility soluble

Melting Point Decomposes

Formula C6H8 N2 O3 S

Boiling Point °Cat760mmHg

Molecular Weight 188.207

Flash Point °C

Transport Information 25kgs

Appearance yellow powder

Safety Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of SO_x and NO_x.

Risk Codes 36/37/38

Molecular Structure

Hazard Symbols UN NO.

Synonyms Benzenesulfonicacid, 4-hydrazino- (9CI); Benzenesulfonic acid, p-hydrazino- (6CI,7CI,8CI);4-Hydrazinobenzenesulfonic acid; 4-Sulfophenylhydrazine; NSC 1608;Phenylhydrazine-4-sulfonic acid; Phenylhydrazine-p-sulfonic acid;p-Hydrazinobenzenesulfonic acid; p-Hydrazinophenylsulfonic acid;p-Sulfophenylhydrazine

PSA 100.80000

LogP 2.07300

Synthetic route

2154-66-7
4-sulfobenzenediazonium

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

Stage #1: 4-sulfobenzenediazonium With sodium sulphite-heptahydrate In water at 0 - 5℃; for 2h;
Stage #2: With hydrogenchloride In water for 0.5h; 96%

With sulfuric acid; sodium sulfite at 0 - 5℃; 95%

121-57-3
4-aminobenzene sulfonic acid

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

Stage #1: 4-aminobenzene sulfonic acid With sulfuric acid; sodium carbonate; sodium nitrite In water at 5℃;
Stage #2: With hydrogenchloride; sodium sulfite In water at 5℃; Reflux; 85%

Stage #1: 4-aminobenzene sulfonic acid With sulfuric acid; sodium carbonate; sodium nitrite In water at 12℃; Cooling with ice;
Stage #2: With sodium sulfite In water at 5℃; Heating;
Stage #3: With hydrogenchloride; zinc In water at 20℃; for 12h; 74%

Diazotization.Behandeln mit Na2SO3 und Spalten mit Salzsaeure;

4-Sulfo-benzenediazonium; hydrogen sulfate

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

Stage #1: 4-Sulfo-benzenediazonium; hydrogen sulfate With sodium sulfite In water Heating / reflux;
Stage #2: With hydrogenchloride In water 85%

305-80-6
4-diazobenzenesulfonic acid

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

With potassium sulfite Kochen mit konz. Salzsaeure;

With sodium dithionite Hydrolyse des Reaktionsprodukts mit kochender Salzsaeure;

61734-81-4
4-nitroamino-benzenesulfonic acid

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

With sodium amalgam

64-17-5
ethanol

4-[N'-(α-hydroxy-3,4-methylenedioxy-benzyl)-hydrazino]-benzenesulfonic acid

A

120-57-0
piperonal

B

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

allmaehliche Zersetzung;

...Expand

4-[N'-(α-hydroxy-3,4-methylenedioxy-benzyl)-hydrazino]-benzenesulfonic acid

64-19-7
acetic acid

A

120-57-0
piperonal

B

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

schnelle Zersetzung;

...Expand

100-63-0
phenylhydrazine

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

With sulfuric acid at 80 - 100℃;

4-[N'-(α-hydroxy-3,4-methylenedioxy-benzyl)-hydrazino]-benzenesulfonic acid

7732-18-5
water

A

120-57-0
piperonal

B

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

allmaehliche Zersetzung;

...Expand

4-[N'-(α-hydroxy-3,4-methylenedioxy-benzyl)-hydrazino]-benzenesulfonic acid

hot water

hot water

A

120-57-0
piperonal

B

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

schnelle Zersetzung;

...Expand

4-[N'-(α-hydroxy-3,4-methylenedioxy-benzyl)-hydrazino]-benzenesulfonic acid

mineral acid

mineral acid

A

120-57-0
piperonal

B

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

schnelle Zersetzung;

...Expand

7664-93-9
sulfuric acid

100-63-0
phenylhydrazine

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

unter Kuehlung und anschl. Erwaermen auf 80-100grad;

disodium-salt of/the/ 4-cis-azo>-benzene-sulfonic acid-(1)

disodium-salt of/the/ 4-cis-azo>-benzene-sulfonic acid-(1)

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

With sodium hydroxide Reduktion an einer Quecksilber-Kathode;

disodium-salt of/the/ 4-trans-azo>-benzene-sulfonic acid-(1)

disodium-salt of/the/ 4-trans-azo>-benzene-sulfonic acid-(1)

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

With sodium hydroxide Reduktion an einer Quecksilber-Kathode;

121-57-3
4-aminobenzene sulfonic acid

hydroxylamine-O-sulfonic acid

hydroxylamine-O-sulfonic acid

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

With sodium hydroxide

p-diazobenzenesulfonate sodium

p-diazobenzenesulfonate sodium

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

With sodium amalgam

potassium salt of/the/ phenylhydrazine-4.α.β-trisulfonic acid

potassium salt of/the/ phenylhydrazine-4.α.β-trisulfonic acid

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

With hydrogenchloride

potassium salt of/the/ phenylhydrazine-4.β-disulfonic acid

potassium salt of/the/ phenylhydrazine-4.β-disulfonic acid

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

With hydrogenchloride

7647-01-0
hydrogenchloride

305-80-6
4-diazobenzenesulfonic acid

diluted alkali

diluted alkali

potassium sulfite

potassium sulfite

98-71-5
4-hydrazino-benzenesulfonic acid

...Expand

61734-81-4
4-nitroamino-benzenesulfonic acid

sodium amalgam

sodium amalgam

alkali

alkali

98-71-5
4-hydrazino-benzenesulfonic acid

...Expand

118834-04-1
(E)-4-hydroxyazo-benzenesulfonic acid ; disodium-salt

sodium amalgam

sodium amalgam

alkali

alkali

98-71-5
4-hydrazino-benzenesulfonic acid

...Expand

4-(N'-sulfo-hydrazino)-benzenesulfonic acid ; dipotassium-salt

strong hydrochloric acid

strong hydrochloric acid

98-71-5
4-hydrazino-benzenesulfonic acid

4-(N,N'-disulfo-hydrazino)-benzenesulfonic acid ; tripotassium-salt trihydrate

hydrochloric acid

hydrochloric acid

A

98-71-5
4-hydrazino-benzenesulfonic acid

B
sulfuric acid

sulfuric acid

...Expand

HSO3(2-)

2154-66-7
4-sulfobenzenediazonium

98-71-5
4-hydrazino-benzenesulfonic acid

Conditions

Conditions Yield

In not given

In not given

563-80-4
3-methyl-butan-2-one

98-71-5
4-hydrazino-benzenesulfonic acid

132557-72-3
2,3,3-trimethylindole-5-sulfonic acid

Conditions

Conditions Yield

With acetic acid for 3h; Concentration; Fischer Indole Synthesis; Reflux; 97%

With acetic acid for 14h; Reflux; 94%

With acetic acid at 120℃; Fischer Indole Synthesis; 94%

100-52-7
benzaldehyde

98-71-5
4-hydrazino-benzenesulfonic acid

hydrazone 4-[(2Z)-2-benzylidenehydrazinyl]benzenesulfonic acid

Conditions

Conditions Yield

Stage #1: 4-hydrazino-benzenesulfonic acid With sodium hydroxide In water at 45℃; for 0.5h; pH=10;
Stage #2: benzaldehyde In water at 55 - 60℃; for 3.5h; 97%

With 1-deoxy-1-(methylamino)-D-glucitol In ethanol; water at 20℃; for 0.5h; 96%

Stage #1: 4-hydrazino-benzenesulfonic acid With sodium hydroxide In water at 45℃; for 0.5h; pH=Ca. 10;
Stage #2: benzaldehyde at 55 - 60℃; for 3h;

91-56-5
indole-2,3-dione

551-93-9
2-aminoacetophenone

98-71-5
4-hydrazino-benzenesulfonic acid

C22H15N3O4S

Conditions

Conditions Yield

In ethanol for 0.3h; Inert atmosphere; Reflux; 94%

...Expand

443-69-6
5-fluoro-1H-indole-2,3-dione

551-93-9
2-aminoacetophenone

98-71-5
4-hydrazino-benzenesulfonic acid

C22H14FN3O4S

Conditions

Conditions Yield

In ethanol for 0.25h; Inert atmosphere; Reflux; 94%

...Expand

87-48-9
5-Bromo-1H-indole-2,3-dione

551-93-9
2-aminoacetophenone

98-71-5
4-hydrazino-benzenesulfonic acid

C22H14BrN3O4S

Conditions

Conditions Yield

In ethanol for 0.266667h; Inert atmosphere; Reflux; 93%

...Expand

551-93-9
2-aminoacetophenone

98-71-5
4-hydrazino-benzenesulfonic acid

82-86-0
acenaphthene quinone

C26H16N2O4S

Conditions

Conditions Yield

In ethanol for 0.366667h; Inert atmosphere; Reflux; 92%

...Expand

563-80-4
3-methyl-butan-2-one

98-71-5
4-hydrazino-benzenesulfonic acid

potassium 2,3,3-trimethylindole-5-sulfonate

Conditions

Conditions Yield

Stage #1: 3-methyl-butan-2-one; 4-hydrazino-benzenesulfonic acid With acetic acid for 4h; Reflux;
Stage #2: With potassium hydroxide In methanol; propan-1-ol at 20℃; for 24h; 90%

Stage #1: 3-methyl-butan-2-one; 4-hydrazino-benzenesulfonic acid With acetic acid for 3h; Reflux;
Stage #2: With potassium hydroxide In methanol; isopropyl alcohol Cooling with ice; Sonication; 80%

Stage #1: 3-methyl-butan-2-one; 4-hydrazino-benzenesulfonic acid In acetic acid at 105℃; for 2.33333h; Heating / reflux;
Stage #2: With potassium acetate In methanol; acetic acid 77%

1445-73-4
1-Methyl-4-piperidone

551-93-9
2-aminoacetophenone

98-71-5
4-hydrazino-benzenesulfonic acid

C20H21N3O3S

Conditions

Conditions Yield

In ethanol for 0.466667h; Inert atmosphere; Reflux; 90%

...Expand

551-93-9
2-aminoacetophenone

98-71-5
4-hydrazino-benzenesulfonic acid

529-34-0
3,4-dihydronaphthalene-1(2H)-one

C24H20N2O3S

Conditions

Conditions Yield

In ethanol for 0.4h; Inert atmosphere; Reflux; 90%

...Expand

611-09-6
5-nitroisatin

551-93-9
2-aminoacetophenone

98-71-5
4-hydrazino-benzenesulfonic acid

C22H14N4O6S

Conditions

Conditions Yield

In ethanol for 0.416667h; Inert atmosphere; Reflux; 89%

...Expand

608-05-9
5-methyl-indole-2,3-dione

551-93-9
2-aminoacetophenone

98-71-5
4-hydrazino-benzenesulfonic acid

C23H17N3O4S

Conditions

Conditions Yield

In ethanol for 0.4h; Inert atmosphere; Reflux; 88%

...Expand

98-71-5
4-hydrazino-benzenesulfonic acid

1118-60-1
3-iminobutyronitrile

69075-48-5
5-amino-3-methyl-1-(4-sulfophenyl)pyrazole

Conditions

Conditions Yield

Stage #1: 4-hydrazino-benzenesulfonic acid; 3-iminobutyronitrile for 1h; Condensation; Heating;
Stage #2: With hydrogenchloride for 2h; Cyclization; Heating; 85.6%

527-69-5
2-furancarbonyl chloride

108-94-1
cyclohexanone

98-71-5
4-hydrazino-benzenesulfonic acid

9-(furan-2-carbonyl)-6,7,8,9-tetrahydro-5H-carbazole-3-sulfonic acid

Conditions

Conditions Yield

Stage #1: 4-hydrazino-benzenesulfonic acid With polystyrene aldehyde resin; triethylamine In 1,2-dichloro-ethane at 45℃;
Stage #2: 2-furancarbonyl chloride With pyridine at 80℃;
Stage #3: cyclohexanone With trifluoroacetic acid In 1,2-dichloro-ethane at 70℃; 85%

...Expand

98-71-5
4-hydrazino-benzenesulfonic acid

1218-69-5
2-(2-hydroxyphenyl)-4H-benzo[e][1,3]oxazin-4-one

4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzenesulfonic acid

Conditions

Conditions Yield

With triethylamine In ethanol for 20h; Heating; 85%

688339-30-2
5-methyl-6-oxoheptane-1-sulphonic acid

98-71-5
4-hydrazino-benzenesulfonic acid

688339-34-6
2,3-dimethyl-3-(4-sulphobutyl)-3H-indole-5-sulphonicacid

Conditions

Conditions Yield

With acetic acid for 6h; Reflux; 85%

With acetic acid for 6h; Heating / reflux;

With acetic acid for 6h; Heating / reflux;

720-94-5
4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione

98-71-5
4-hydrazino-benzenesulfonic acid

4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfinic acid

Conditions

Conditions Yield

With hydrogenchloride In ethanol Reflux; 85%

99183-34-3
6-methyl-7-oxooctanoic acid

98-71-5
4-hydrazino-benzenesulfonic acid

1072069-89-6
potassium 3-(4-carboxybutyl)-2,3-dimethylindolenine-5-sulfonate

Conditions

Conditions Yield

Stage #1: 6-methyl-7-oxooctanoic acid; 4-hydrazino-benzenesulfonic acid With acetic acid for 8h; Reflux;
Stage #2: With potassium hydroxide In methanol; diethyl ether; isopropyl alcohol 83%

Stage #1: 6-methyl-7-oxooctanoic acid; 4-hydrazino-benzenesulfonic acid In acetic acid for 8h; Reflux;
Stage #2: With potassium hydroxide In methanol; diethyl ether; isopropyl alcohol 83%

98-71-5
4-hydrazino-benzenesulfonic acid

708-06-5
2-hydroxynaphthalene-1-carbaldehyde

C17H14N2O4S

Conditions

Conditions Yield

With toluene-4-sulfonic acid In ethanol at 80℃; 83%

720-94-5
4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione

98-71-5
4-hydrazino-benzenesulfonic acid

921617-76-7
4-(5-p-methylphenyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonic acid

Conditions

Conditions Yield

With hydrogenchloride In ethanol; water at 20℃; for 8h; Heating / reflux; 82%

With hydrogenchloride In ethanol for 8h; Heating; 82%

C35H44N2O5S3

98-71-5
4-hydrazino-benzenesulfonic acid

C41H49N4O7S4(1-)*H4N(1+)

Conditions

Conditions Yield

Stage #1: C35H44N2O5S3 With hydrogenchloride In methanol at 90℃;
Stage #2: 4-hydrazino-benzenesulfonic acid In ethanol; water at 90℃; for 16h; Inert atmosphere; 82%

563-80-4
3-methyl-butan-2-one

98-71-5
4-hydrazino-benzenesulfonic acid

ammonium 2,3,3-trimethyl-3H-indole-5-sulfonate

Conditions

Conditions Yield

With acetic acid at 118℃; for 18h; Inert atmosphere; 80%

With acetic acid at 118℃; for 18h; Inert atmosphere; 80%

6940-49-4
3-Bromophthalide

98-71-5
4-hydrazino-benzenesulfonic acid

1'-(1-oxophthalazin-2(1H)-yl)benzenesulfonic acid

Conditions

Conditions Yield

Stage #1: 3-Bromophthalide With hydrogenchloride In water for 2h; Reflux;
Stage #2: 4-hydrazino-benzenesulfonic acid In water at 20℃; for 2h; 76%

5601-58-1
rac-methyl 6-methyl-7-oxooctanoate

98-71-5
4-hydrazino-benzenesulfonic acid

sodium 3-(5-methoxy-5-oxopentyl)-2,3-dimethyl-3H-indole-5-sulfonate

Conditions

Conditions Yield

Stage #1: rac-methyl 6-methyl-7-oxooctanoate; 4-hydrazino-benzenesulfonic acid With acetic acid for 4h; Fischer Indole Synthesis; Reflux;
Stage #2: With sodium carbonate In methanol at 20℃; for 15h; 76%

100-52-7
benzaldehyde

98-71-5
4-hydrazino-benzenesulfonic acid

benzaldehyde (4-sulfophenyl)hydrazone

Conditions

Conditions Yield

With acetic acid In water at 60℃; for 3h; pH=3; 72%

563-80-4
3-methyl-butan-2-one

98-71-5
4-hydrazino-benzenesulfonic acid

2,3,3,-trimethylindoleninium-5-sulfonate potassium salt

Conditions

Conditions Yield

Stage #1: 3-methyl-butan-2-one; 4-hydrazino-benzenesulfonic acid With acetic acid at 115℃; for 4h; Inert atmosphere;
Stage #2: With potassium hydroxide In methanol; isopropyl alcohol 69.5%

952292-10-3
4-methyl-5-oxohexane sulfonic acid

98-71-5
4-hydrazino-benzenesulfonic acid

2,3-dimethyl-3-(3-sulfopropyl)indoleninium-5-sulfonate potassium salt

Conditions

Conditions Yield

Stage #1: 4-methyl-5-oxohexane sulfonic acid; 4-hydrazino-benzenesulfonic acid With acetic acid at 115℃; for 30h; Inert atmosphere; Reflux;
Stage #2: With potassium hydroxide In methanol; isopropyl alcohol at 50℃; for 18h; 68.4%

5271-67-0
2-Thiophenecarbonyl chloride

108-94-1
cyclohexanone

98-71-5
4-hydrazino-benzenesulfonic acid

9-(thiophene-2-carbonyl)-6,7,8,9-tetrahydro-5H-carbazole-3-sulfonic acid

Conditions

Conditions Yield

Stage #1: 4-hydrazino-benzenesulfonic acid With polystyrene aldehyde resin; triethylamine In 1,2-dichloro-ethane at 45℃;
Stage #2: 2-Thiophenecarbonyl chloride With pyridine at 80℃;
Stage #3: cyclohexanone With trifluoroacetic acid In 1,2-dichloro-ethane at 70℃; 66%

...Expand

4-Hydrazinobenzenesulfonic acid Chemical Properties
Phenylhydrazine-p-Sulfonic Acid(98-71-5) is also named as 4-hydrazino-benzenesulfonicaci;4-sulfophenylhydrazine;6,7-Dihydro-5,8-dimethyldibenzo[b,j][1,10]phenanthroline;Phenylhydrazinesulfonic acid;Sulfanilic acid, N-amino-;p-Hydrazinophenylsulfonic acid;p-Hydrazinobenzenesulfonic acid,and so on.Phenylhydrazine-p-Sulfonic Acid(98-71-5) is white to light yellow crystal powder.
CAS: 98-71-5
Molecular Formula: C₆H₈N₂O₃S
Molecular Weight: 188.2
Molecular structure:
EINECS: 202-694-2
Melting point: 285°C
Merck: 4773
Index of Refraction: 1.669
Molar Refractivity: 44.37 cm³
Molar Volume: 118.8 cm³
Polarizability: 17.59 10^-24cm³
Surface Tension: 80.9 dyne/cm
Density: 1.583 g/cm³
4-Hydrazinobenzenesulfonic acid Uses
Phenylhydrazine-p-Sulfonic Acid(98-71-5) is commonly used as a dye intermediate.
4-Hydrazinobenzenesulfonic acid Toxicity Data With Reference
1.
orl-rat LDLo:500 mg/kg
JPETAB Journal of Pharmacology and Experimental Therapeutics. 90 (1947),260.
RTECS: DB6900000
4-Hydrazinobenzenesulfonic acid Consensus Reports
Reported in EPA TSCA Inventory.
4-Hydrazinobenzenesulfonic acid Safety Profile
Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of SO_x and NO_x.
Hazard Codes: Xi
Risk Statements: 36/37/38 (36/37/38: Irritating to eyes, respiratory system and skin)
Safety Statements: 26-36/37/39 (26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 36/37/39: Wear suitable protective clothing, gloves and eye/face protection)
Hazard Note: Irritant

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Conditions	Yield
Stage #1: 4-sulfobenzenediazonium With sodium sulphite-heptahydrate In water at 0 - 5℃; for 2h; Stage #2: With hydrogenchloride In water for 0.5h;	96%
With sulfuric acid; sodium sulfite at 0 - 5℃;	95%

Conditions	Yield
Stage #1: 4-aminobenzene sulfonic acid With sulfuric acid; sodium carbonate; sodium nitrite In water at 5℃; Stage #2: With hydrogenchloride; sodium sulfite In water at 5℃; Reflux;	85%
Stage #1: 4-aminobenzene sulfonic acid With sulfuric acid; sodium carbonate; sodium nitrite In water at 12℃; Cooling with ice; Stage #2: With sodium sulfite In water at 5℃; Heating; Stage #3: With hydrogenchloride; zinc In water at 20℃; for 12h;	74%
Diazotization.Behandeln mit Na2SO3 und Spalten mit Salzsaeure;

Conditions	Yield
With potassium sulfite Kochen mit konz. Salzsaeure;
With sodium dithionite Hydrolyse des Reaktionsprodukts mit kochender Salzsaeure;

Conditions	Yield
With acetic acid for 3h; Concentration; Fischer Indole Synthesis; Reflux;	97%
With acetic acid for 14h; Reflux;	94%
With acetic acid at 120℃; Fischer Indole Synthesis;	94%

Conditions	Yield
Stage #1: 4-hydrazino-benzenesulfonic acid With sodium hydroxide In water at 45℃; for 0.5h; pH=10; Stage #2: benzaldehyde In water at 55 - 60℃; for 3.5h;	97%
With 1-deoxy-1-(methylamino)-D-glucitol In ethanol; water at 20℃; for 0.5h;	96%
Stage #1: 4-hydrazino-benzenesulfonic acid With sodium hydroxide In water at 45℃; for 0.5h; pH=Ca. 10; Stage #2: benzaldehyde at 55 - 60℃; for 3h;

Conditions	Yield
Stage #1: 3-methyl-butan-2-one; 4-hydrazino-benzenesulfonic acid With acetic acid for 4h; Reflux; Stage #2: With potassium hydroxide In methanol; propan-1-ol at 20℃; for 24h;	90%
Stage #1: 3-methyl-butan-2-one; 4-hydrazino-benzenesulfonic acid With acetic acid for 3h; Reflux; Stage #2: With potassium hydroxide In methanol; isopropyl alcohol Cooling with ice; Sonication;	80%
Stage #1: 3-methyl-butan-2-one; 4-hydrazino-benzenesulfonic acid In acetic acid at 105℃; for 2.33333h; Heating / reflux; Stage #2: With potassium acetate In methanol; acetic acid	77%

Conditions	Yield
With acetic acid for 6h; Reflux;	85%
With acetic acid for 6h; Heating / reflux;
With acetic acid for 6h; Heating / reflux;

Conditions	Yield
Stage #1: 6-methyl-7-oxooctanoic acid; 4-hydrazino-benzenesulfonic acid With acetic acid for 8h; Reflux; Stage #2: With potassium hydroxide In methanol; diethyl ether; isopropyl alcohol	83%
Stage #1: 6-methyl-7-oxooctanoic acid; 4-hydrazino-benzenesulfonic acid In acetic acid for 8h; Reflux; Stage #2: With potassium hydroxide In methanol; diethyl ether; isopropyl alcohol	83%

Conditions	Yield
With hydrogenchloride In ethanol; water at 20℃; for 8h; Heating / reflux;	82%
With hydrogenchloride In ethanol for 8h; Heating;	82%

Conditions	Yield
With acetic acid at 118℃; for 18h; Inert atmosphere;	80%
With acetic acid at 118℃; for 18h; Inert atmosphere;	80%

Product Name

4-Hydrazinobenzenesulfonic acid

Synthetic route

4-Hydrazinobenzenesulfonic acid Chemical Properties

4-Hydrazinobenzenesulfonic acid Uses

4-Hydrazinobenzenesulfonic acid Toxicity Data With Reference

4-Hydrazinobenzenesulfonic acid Consensus Reports

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