Product Name

  • Name

    4-Hydroxybenzenesulfonic acid

  • EINECS 202-691-6
  • CAS No. 98-67-9
  • Article Data69
  • CAS DataBase
  • Density 1.574 g/cm3
  • Solubility Soluble in water.
  • Melting Point 50(分解)oC
  • Formula C6H6O4S
  • Boiling Point 275.14°C (rough estimate)
  • Molecular Weight 174.177
  • Flash Point
  • Transport Information UN 2586 8/PG 3
  • Appearance yellowish oily liquid
  • Safety 26-36/37/39-45
  • Risk Codes 34
  • Molecular Structure Molecular Structure of 98-67-9 (4-Hydroxybenzenesulfonic acid)
  • Hazard Symbols CorrosiveC
  • Synonyms Benzenesulfonicacid, p-hydroxy- (8CI);Benzenesulfonic acid,4-hydroxy-;4-Hydroxyphenylsulfonicacid;4-Phenolsulfonic acid;NSC 227908;p-Hydroxybenzenesulfonic acid;p-Phenolsulfonic acid;p-Sulfophenol;phenol sulfonic acid;4-Hydroxyphenylsulfonic acid;
  • PSA 82.98000
  • LogP 1.71970

Synthetic route

ethanol
64-17-5

ethanol

2-hydroxy-5-sulfo-benzenediazonium-betaine
391859-81-7

2-hydroxy-5-sulfo-benzenediazonium-betaine

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

4-sulfobenzenediazonium
2154-66-7

4-sulfobenzenediazonium

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
With water
4-diazobenzenesulfonic acid
305-80-6

4-diazobenzenesulfonic acid

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
Geschwindigkeit der Zersetzung bei Ultraviolett-Bestrahlung zwischen pH 1und 10 und Temperaturen zwischen 35grad und 100grad;
4-chloro-benzenesulfonic acid
98-66-8

4-chloro-benzenesulfonic acid

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
With sodium hydroxide at 300℃;
With quicklime; water; copper at 180 - 200℃;
With barium dihydroxide; water; copper at 180 - 200℃;
With quicklime; water at 180 - 200℃; in Gegenwart von Kupferverbindungen;
With barium dihydroxide; water at 180 - 200℃; in Gegenwart von Kupferverbindungen;
p-bromobenzene sulfonic acid
138-36-3

p-bromobenzene sulfonic acid

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
With quicklime; water; copper at 180 - 200℃;
With barium dihydroxide; water; copper at 180 - 200℃;
With quicklime; water at 180 - 200℃; in Gegenwart von Kupferverbindungen;
With barium dihydroxide; water at 180 - 200℃; in Gegenwart von Kupferverbindungen;
4-ethoxybenzonitrile
25117-74-2

4-ethoxybenzonitrile

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
With sulfuric acid
phenol-2-sulfonic acid
609-46-1

phenol-2-sulfonic acid

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
With sulfuric acid
2-amino-4-hydroxy-benzenesulfonic acid
5857-93-2

2-amino-4-hydroxy-benzenesulfonic acid

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
Erhitzen der entstandenen Diazoverbindung mit Alkohol und Kupferpulver.Diazotization;
6.4'-Dioxy-3-methyl-diphenylsulfon
156570-57-9

6.4'-Dioxy-3-methyl-diphenylsulfon

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

4-hydroxy-toluene-3-sulfonic acid
7134-06-7

4-hydroxy-toluene-3-sulfonic acid

Conditions
ConditionsYield
With sulfuric acid
phenyl Salicylate
118-55-8

phenyl Salicylate

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
With sulfuric acid
methoxybenzene
100-66-3

methoxybenzene

dimethyl sulfate
77-78-1

dimethyl sulfate

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
at 95 - 120℃;
phenyldiazoniumsulfate

phenyldiazoniumsulfate

toluene
108-88-3

toluene

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

phenol
108-95-2

phenol

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
at 95 - 120℃;
dimethyl sulfate
77-78-1

dimethyl sulfate

phenol
108-95-2

phenol

A

methyl bisulfate
75-93-4

methyl bisulfate

B

Dimethyl ether
115-10-6

Dimethyl ether

C

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

D

methoxybenzene
100-66-3

methoxybenzene

Conditions
ConditionsYield
at 100 - 120℃; anderen Produkten: p-Phenol-sulfonsaeuremethylester; p-Anisolsulfonsaeure; p-Anisolsulfonsaeuremethylester;
benzenesulfonic acid
98-11-3

benzenesulfonic acid

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
With water; platinum Electrolysis;
With water; lead dioxide Electrolysis;
phenol
108-95-2

phenol

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
With sulfuric acid at 90 - 100℃; Isolierung als Natriumsalz;
With sulfuric acid; boron trifluoride
With copper(II) hydroxide; ammonium bisulfite; ammonia; water; oxygen
phenol
108-95-2

phenol

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

phenol sulfate
937-34-8

phenol sulfate

Conditions
ConditionsYield
With carbon disulfide; chlorosulfonic acid at -15℃;
phenol
108-95-2

phenol

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

4-hydroxy-benzene-1,3-disulfonic acid
96-77-5

4-hydroxy-benzene-1,3-disulfonic acid

Conditions
ConditionsYield
With sulfuric acid at 100℃;
With sulfur trioxide at 100℃; for 4h;
phenol
108-95-2

phenol

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

phenol-2-sulfonic acid
609-46-1

phenol-2-sulfonic acid

Conditions
ConditionsYield
With sulfuric acid at 90 - 100℃;
With chlorosulfonic acid
With sulfuric acid
With 5-bromopyrimidine; sulfuric acid In water at 20℃;
4-hydroxy-benzene-1,3-disulfonic acid
96-77-5

4-hydroxy-benzene-1,3-disulfonic acid

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

phenol-2-sulfonic acid
609-46-1

phenol-2-sulfonic acid

C

phenol-2,4,6-trisulfonic acid
5930-44-9

phenol-2,4,6-trisulfonic acid

D

phenol
108-95-2

phenol

Conditions
ConditionsYield
With sodium hydrogen sulfate; sulfuric acid; water equilibrium compositions at 140 and 170 deg C;
methyl phenyl sulfate
66735-55-5

methyl phenyl sulfate

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

4-hydroxy-benzene-1,3-disulfonic acid
96-77-5

4-hydroxy-benzene-1,3-disulfonic acid

C

4-Methoxysulfonyloxy-benzenesulfonic acid

4-Methoxysulfonyloxy-benzenesulfonic acid

Conditions
ConditionsYield
With sulfuric acid at 25℃; Product distribution; varying reagent concentration;A 12 % Spectr.
B 47 % Spectr.
C 6 % Spectr.
phenol-2-sulfonic acid
609-46-1

phenol-2-sulfonic acid

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

4-hydroxy-benzene-1,3-disulfonic acid
96-77-5

4-hydroxy-benzene-1,3-disulfonic acid

C

phenol-2,4,6-trisulfonic acid
5930-44-9

phenol-2,4,6-trisulfonic acid

D

phenol
108-95-2

phenol

Conditions
ConditionsYield
With sodium hydrogen sulfate; sulfuric acid; water equilibrium compositions at 140 and 170 deg C;
4-hydroxybenzenesulfinic acid
3724-13-8

4-hydroxybenzenesulfinic acid

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
With dihydrogen peroxide In water-d2
4-Trimethylsiloxy-1-benzolsulfonsaeure-trimethylsilylester
81293-04-1

4-Trimethylsiloxy-1-benzolsulfonsaeure-trimethylsilylester

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
With water Yield given;
phenol-2,4,6-trisulfonic acid
5930-44-9

phenol-2,4,6-trisulfonic acid

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

4-hydroxy-benzene-1,3-disulfonic acid
96-77-5

4-hydroxy-benzene-1,3-disulfonic acid

C

phenol-2-sulfonic acid
609-46-1

phenol-2-sulfonic acid

D

phenol
108-95-2

phenol

Conditions
ConditionsYield
With sodium hydrogen sulfate; sulfuric acid; water equilibrium compositions at 140 and 170 deg C;
potassium phenyl sulphate
1733-88-6

potassium phenyl sulphate

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

phenol-2-sulfonic acid
609-46-1

phenol-2-sulfonic acid

Conditions
ConditionsYield
With sulfuric acid at 25℃;A 53 % Spectr.
B 47 % Spectr.
With sulfuric acid at 25℃;A 51 % Spectr.
B 49 % Spectr.
4-hydroxybenzenesulfonate sulfate
118795-68-9

4-hydroxybenzenesulfonate sulfate

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

Conditions
ConditionsYield
With 1,3-Dimethoxybenzene In 1,4-dioxane-d8 at 17℃; Rate constant;
phenol
108-95-2

phenol

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

phenol sulfate
937-34-8

phenol sulfate

C

phenol-2-sulfonic acid
609-46-1

phenol-2-sulfonic acid

Conditions
ConditionsYield
With sulfur trioxide In dichloromethane at -20℃; for 1h; Product distribution; Mechanism; different temp., different time;
With sulfur trioxide In dichloromethane at -50℃; for 0.5h; Title compound not separated from byproducts;
phenol
108-95-2

phenol

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

phenol sulfate
937-34-8

phenol sulfate

C

4-hydroxybenzenesulfonate sulfate
118795-68-9

4-hydroxybenzenesulfonate sulfate

Conditions
ConditionsYield
With sulfur trioxide In nitromethane-d3 at -35℃; for 0.25h; Product distribution; various solvents, times, temperatures, amounts of SO3;
phenol
108-95-2

phenol

A

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

B

4-hydroxy-benzene-1,3-disulfonic acid
96-77-5

4-hydroxy-benzene-1,3-disulfonic acid

C

phenol-2-sulfonic acid
609-46-1

phenol-2-sulfonic acid

Conditions
ConditionsYield
With sulfuric acid at 25℃; Kinetics; Mechanism; Product distribution; variation of H2SO4 concentration;A 53 % Spectr.
B n/a
C 47 % Spectr.
With sulfuric acid at 25℃;A 53 % Spectr.
B n/a
C 47 % Spectr.
With sulfuric acid at 25℃;A 49 % Spectr.
B n/a
C 51 % Spectr.
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

pivaloyl chloride
3282-30-2

pivaloyl chloride

4-(2,2-dimethylpropanoyloxy)benzenesulfonic acid

4-(2,2-dimethylpropanoyloxy)benzenesulfonic acid

Conditions
ConditionsYield
With triethylamine In ethyl acetate at 20℃; for 12h; Green chemistry;99%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

benzoyl chloride
98-88-4

benzoyl chloride

4-(benzoyloxy)benzenesulfonic acid
61308-40-5

4-(benzoyloxy)benzenesulfonic acid

Conditions
ConditionsYield
With triethylamine In ethyl acetate at 20℃; for 12h; Green chemistry;98%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

1-bromomethyl-3-chlorobenzene
766-80-3

1-bromomethyl-3-chlorobenzene

sodium 4-(3-chlorobenzyloxy)benzenesulfonate

sodium 4-(3-chlorobenzyloxy)benzenesulfonate

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 100℃; for 18h;96%
chlorure d'acide ethyl-2 butyrique
2736-40-5

chlorure d'acide ethyl-2 butyrique

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

4-(2-ethylbutanoyloxy)benzenesulfonic acid

4-(2-ethylbutanoyloxy)benzenesulfonic acid

Conditions
ConditionsYield
With triethylamine In ethyl acetate at 20℃; for 12h; Green chemistry;96%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

4-methyl-benzoyl chloride
874-60-2

4-methyl-benzoyl chloride

4-(4-methylbenzoyloxy)benzenesulfonic acid

4-(4-methylbenzoyloxy)benzenesulfonic acid

Conditions
ConditionsYield
With triethylamine In ethyl acetate at 20℃; for 12h; Green chemistry;96%
dabigatran etexilate
211915-06-9

dabigatran etexilate

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

dabigatran etexilate p-hydroxybenzenesulfonate

dabigatran etexilate p-hydroxybenzenesulfonate

Conditions
ConditionsYield
In ethyl acetate at 30℃; Solvent; Temperature;94%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

4-hydroxy-benzoic acid
99-96-7

4-hydroxy-benzoic acid

Conditions
ConditionsYield
With tetrakis(acetonitrile)palladium(II) tetrafluoroborate; 1,2-bis[di(t-butyl)phosphinomethyl]benzene In toluene at 140℃; for 5h; Autoclave;93%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

acetyl chloride
75-36-5

acetyl chloride

4-(acetyloxy)benzenesulfonic acid
46331-24-2

4-(acetyloxy)benzenesulfonic acid

Conditions
ConditionsYield
With triethylamine In ethyl acetate at 20℃; for 12h; Green chemistry;92%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

pentaphenylantimony
2170-05-0

pentaphenylantimony

tetraphenylantimony 4-hydroxybenzenesulfonate

tetraphenylantimony 4-hydroxybenzenesulfonate

Conditions
ConditionsYield
In toluene few minutes at room temperature;90%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

pentaphenylbismuth
3049-07-8

pentaphenylbismuth

tetraphenylbismuth 4-hydroxybenzenesulfonate
955409-88-8, 955409-92-4

tetraphenylbismuth 4-hydroxybenzenesulfonate

Conditions
ConditionsYield
In benzene mixt. of 4-sulfophenol and BiPh5 in C6H6 kept at 20°C for 0.5 h; solvent removed, washed (hexane), dried; elem. anal.;90%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

pentaphenylantimony
2170-05-0

pentaphenylantimony

tetraphenylantimony 4-hydroxybenzenesulfonate
209463-67-2

tetraphenylantimony 4-hydroxybenzenesulfonate

Conditions
ConditionsYield
In benzene mixt. of 4-sulfophenol and BiPh5 in C6H6 kept at 20°C for 0.5 h; solvent removed, washed (hexane), dried; elem. anal.;90%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

n-valeryl chloride
638-29-9

n-valeryl chloride

4-(pentanoyloxy)benzenesulfonic acid

4-(pentanoyloxy)benzenesulfonic acid

Conditions
ConditionsYield
With triethylamine In ethyl acetate at 20℃; for 12h; Green chemistry;86%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

1-(p-sulphophenyl)-3-methyl-4-aminopyrazolone

1-(p-sulphophenyl)-3-methyl-4-aminopyrazolone

C16H14N4O8S2

C16H14N4O8S2

Conditions
ConditionsYield
Stage #1: 1-(p-sulphophenyl)-3-methyl-4-aminopyrazolone With hydrogenchloride; sodium nitrite In water for 1h;
Stage #2: p-hydoroxybenzenesulfonic acid With sodium hydroxide In water pH=8 - 9;
84%
1,2-Epoxydecane
2404-44-6

1,2-Epoxydecane

octanol
111-87-5

octanol

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

11-oxa-9-hydroxynonadecane

11-oxa-9-hydroxynonadecane

Conditions
ConditionsYield
With sodium hydroxide In water83%
oxalyl dichloride
79-37-8

oxalyl dichloride

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

4-acetoxybenzenesulfonyl chloride
79119-26-9

4-acetoxybenzenesulfonyl chloride

Conditions
ConditionsYield
With acetic anhydride; acetic acid In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; ethyl acetate; N,N-dimethyl-formamide83%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

1-Bromooctadecane
112-89-0

1-Bromooctadecane

4-(octadecyloxy)benzenesulfonic acid
1245745-24-7

4-(octadecyloxy)benzenesulfonic acid

Conditions
ConditionsYield
Stage #1: p-hydoroxybenzenesulfonic acid; 1-Bromooctadecane With potassium carbonate In acetone for 24h; Reflux; Inert atmosphere;
Stage #2: With hydrogenchloride In tetrahydrofuran Inert atmosphere;
81%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

1-bromomethyl-4-nitro-benzene
100-11-8

1-bromomethyl-4-nitro-benzene

sodium 4-(4-nitrobenzyloxy)benzenesulfonate

sodium 4-(4-nitrobenzyloxy)benzenesulfonate

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 100℃; for 18h;80%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

hexamethylenetetramine
100-97-0

hexamethylenetetramine

water
7732-18-5

water

silver nitrate

silver nitrate

[Ag(hexamethylenetetramine)(4-hydroxybenzenesulfonate)(H2O)]

[Ag(hexamethylenetetramine)(4-hydroxybenzenesulfonate)(H2O)]

Conditions
ConditionsYield
With NH4OH In methanol; water aq. soln. of sulfonic acid added to solid AgNO3, stirred for several min, MeOH soln. hmt added (1:1:1 molar ratio), pptd.; ppt. dissolved in concd. ammonia, crystd. on storage in dark for 3 d, elem. anal.;78%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

1-bromomethyl-4-bromobenzene
589-15-1

1-bromomethyl-4-bromobenzene

sodium 4-(4-bromobenzyloxy)benzenesulfonate

sodium 4-(4-bromobenzyloxy)benzenesulfonate

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 100℃; for 18h;77%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

4-(chloromethyl)-2-methylquinoline
288399-19-9

4-(chloromethyl)-2-methylquinoline

sodium 4-(2-methylquinolin-4-ylmethoxy)benzenesulfonate
477585-26-5

sodium 4-(2-methylquinolin-4-ylmethoxy)benzenesulfonate

Conditions
ConditionsYield
With sodium hydroxide In water; isopropyl alcohol at 40 - 70℃; for 23h;75%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

benzylamine
100-46-9

benzylamine

C6H6O4S*C7H9N

C6H6O4S*C7H9N

Conditions
ConditionsYield
In methanol at 20℃; for 192h;74.65%
2,5-dibromo-1,3-thiazole
4175-78-4

2,5-dibromo-1,3-thiazole

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

4-(5-bromo-thiazol-2-yloxy)-benzenesulfonic acid
904962-01-2

4-(5-bromo-thiazol-2-yloxy)-benzenesulfonic acid

Conditions
ConditionsYield
Stage #1: 2,5-dibromo-1,3-thiazole; p-hydoroxybenzenesulfonic acid With potassium carbonate In water; N,N-dimethyl-formamide at 160℃; for 0.166667h; Microwave irradiation;
Stage #2: With hydrogenchloride In 1,4-dioxane
74%
1-diazopentan-2-one
39910-26-4

1-diazopentan-2-one

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

4-Hydroxy-benzenesulfonic acid 2-oxo-pentyl ester
80519-92-2

4-Hydroxy-benzenesulfonic acid 2-oxo-pentyl ester

Conditions
ConditionsYield
In diethyl ether Ambient temperature;70%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

dimethyl 2-((fluoromethyl)(phenyl)-l4-sulfaneylidene)malonate

dimethyl 2-((fluoromethyl)(phenyl)-l4-sulfaneylidene)malonate

monofluoromethyl 4-hydroxybenzenesulfonate

monofluoromethyl 4-hydroxybenzenesulfonate

Conditions
ConditionsYield
In acetone at 40℃; for 0.0833333h; Schlenk technique; Inert atmosphere;69%
tetrahydrofuran
109-99-9

tetrahydrofuran

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

benzalacetophenone
94-41-7

benzalacetophenone

4-(2-bromo-3-oxo-1,3-diphenylpropoxy)butyl 4-hydroxybenzenesulfonate

4-(2-bromo-3-oxo-1,3-diphenylpropoxy)butyl 4-hydroxybenzenesulfonate

Conditions
ConditionsYield
With N-Bromosuccinimide; zinc(II) chloride for 40h; Inert atmosphere; diastereoselective reaction;68%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

isopropyl bromide
75-26-3

isopropyl bromide

4-isopropoxybenzenesulfonic acid

4-isopropoxybenzenesulfonic acid

Conditions
ConditionsYield
With sodium hydroxide In N,N-dimethyl-formamide at 80℃; for 24h; Sealed tube;68%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

2-cyclohexyl-1-diazo-2-ethanone
31151-40-3

2-cyclohexyl-1-diazo-2-ethanone

4-Hydroxy-benzenesulfonic acid 2-cyclohexyl-2-oxo-ethyl ester
80520-93-0

4-Hydroxy-benzenesulfonic acid 2-cyclohexyl-2-oxo-ethyl ester

Conditions
ConditionsYield
67%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

benzyl bromide
100-39-0

benzyl bromide

4-phenylmethoxybenzenesulfonic acid sodium salt
111712-04-0

4-phenylmethoxybenzenesulfonic acid sodium salt

Conditions
ConditionsYield
With sodium hydroxide In isopropyl alcohol at 70℃; for 20h;66%
With sodium hydroxide In ethanol at 100℃; for 18h;62%
With sodium hydroxide In ethanol; water for 24h; Heating;62%
p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

2-methylbenzyl bromide
89-92-9

2-methylbenzyl bromide

sodium 4-(2-methylbenzyloxy)benzenesulfonate

sodium 4-(2-methylbenzyloxy)benzenesulfonate

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 100℃; for 18h;64%
cadmium sulfate octahydrate

cadmium sulfate octahydrate

p-hydoroxybenzenesulfonic acid
98-67-9

p-hydoroxybenzenesulfonic acid

1,10-phenanthroline hydrate
5144-89-8

1,10-phenanthroline hydrate

potassium hydroxide

potassium hydroxide

Cd(1,10-phenanthroline)2(p-hydroxybenzenesulfonate)2

Cd(1,10-phenanthroline)2(p-hydroxybenzenesulfonate)2

Conditions
ConditionsYield
In water High Pressure; 1 equiv. of metal-salt, 1 equiv. of sulfonic acid, 1 equiv. of N-base and 2.6 equiv. of KOH were stirred in H2O at room temp. for 30 min (pH=7-8), teflon-lined stainless steel reactor, heating at 150 °C for 72h; cooling to room temp., soln. was filtered, evapd. with standing at room temp. for several d, elem. anal.;62%
In water 1 equiv. of metal-salt, 1 equiv. of sulfonic acid, 1 equiv. of N-base and 2.6 equiv. of KOH were stirred in H2O at room temp. (pH=7-8);0%

4-Hydroxybenzenesulfonic acid Chemical Properties

IUPAC: 4-Hydroxybenzenesulfonic acid
Molecular Formula: C6H6O4S
Molecular Weight: 174.17 g/mol
Density: 1.337 g/mL at 25 °C
Refractive Index: n20/D 1.489
Stability: Stable. Combustible. Incompatible with strong oxidizing agents. 
Molar Refractivity: 38.63 cm3
Molar Volume: 110.6 cm3
Polarizability: 15.31×10-24 cm3
Surface Tension: 66.1 dyne/cm
The structure of 4-Hydroxyphenylsulfonic acid (CAS NO.98-67-9):

XLogP3: 0.2
H-Bond Donor: 2
H-Bond Acceptor: 4
Rotatable Bond Count: 1
Tautomer Count: 2
Exact Mass: 173.998679
MonoIsotopic Mass: 173.998679
Topological Polar Surface Area: 74.6
Heavy Atom Count: 11 
Canonical SMILES: C1=CC(=CC=C1O)S(=O)(=O)O
InChI: InChI=1S/C6H6O4S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4,7H,(H,8,9,10)
InChIKey: FEPBITJSIHRMRT-UHFFFAOYSA-N
EINECS: 202-691-6
Product Categories: Intermediates of Dyes and Pigments;Organic acids

4-Hydroxybenzenesulfonic acid Uses

 4-Hydroxyphenylsulfonic acid (CAS NO.98-67-9) is mainly used for the resin cure. It is also used as a casting resin curing agent at room temperature.

4-Hydroxybenzenesulfonic acid Toxicity Data With Reference

1.    

orl-mus LD50:6400 mg/kg

    JAFCAU    Journal of Agricultural and Food Chemistry. 15 (1967),845.

4-Hydroxybenzenesulfonic acid Consensus Reports

Reported in EPA TSCA Inventory.

4-Hydroxybenzenesulfonic acid Safety Profile

Mildly toxic by ingestion. When heated to decomposition it emits toxic vapors of SOx.
Hazard Codes: C
Risk Statements: 34
34: Causes burns
Safety Statements: 26-36/37/39-45 
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36/37/39: Wear suitable protective clothing, gloves and eye/face protection 
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR: UN 2586 8/PG 3
RTECS: DB6970000
HazardClass: 8
PackingGroup: III

4-Hydroxybenzenesulfonic acid Specification

 4-Hydroxyphenylsulfonic acid (CAS NO.98-67-9) is also named as 4-11-00-00582 (Beilstein Handbook Reference) ; 4-Hydroxybenzenesulfonic acid ; 4-Phenolsulfonic acid ; BRN 1869034 ; Benzenesulfonic acid, 4-hydroxy- ; Benzenesulfonic acid, p-hydroxy- ; HSDB 5319 ; NSC 227908 ; Sulfocarbolic acid ; p-Hydroxybenzenesulfonic acid ; p-Phenolsulfonic acid ; p-Sulfophenol . 4-Hydroxyphenylsulfonic acid (CAS NO.98-67-9) is yellowish oily liquid.

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View