Synthetically, 1-(benzo[c]phenanthren-2-yl)ethanol and 1-(benzo[c]phenanthren-2-yl)-3-phenylpropane-1,3-diol were successfully obtained from 2-acetylbenzo[c]phenanthrene and methyl benzo[c]phenanthrene-2-carboxylate, respectively, and fully characterized. The desired compounds were purified by s...

Alkyl phenanthrene-9-carboxylates were synthesized in 74–96% yields by the iron-catalyzed reaction of phenanthrene with tetrachloromethaneand alkanols

Phenanthrene and most of its known derivatives do not form stable, fluorescent excimers. Moderately intense, long-lived excimer fluorescence has been observed for lactone and lactam derivatives of phenanthrene. The solvatochromic shift of this excimer fluorescence is similar to that previously r...

Interaction of TiO2 nanoparticles (NPs) on newly synthesized phenothiazine derivative-(E)-2-cyano-3-(10-decyl-10H-phenothiazin-7-yl) acrylic acid (PTA dye) has been studied using absorption, fluorescence and electrochemical techniques. From the results of absorption spectra of PTA dye in the pre...

To shed more insight into the regioselectivities observed in the reactions between 3,5-diaminopyrazoles and N-acyl imidates or N-ethoxy imidate yielding the corresponding substituted pyrazolo[1,5-a]-[1,3,5] triazines or pyrazolo[1,5-a][1,3,5] triazinones, DFT calculations are carried out using B...

This study focuses on the design, synthesis, molecular modeling and biological evaluation of a novel group of alkyl-1,3,5-triazinyl-methylpiperazines. New compounds were synthesized and their affinities for human histamine H4 receptor (hH4R) were evaluated. Among them, 4-(cyclohexylmethyl)-6-(4-...

1,3-cyclohexadiene (1,3-CHD) can be transformed into cis-1,3,5-hexatriene (1,3,5-HT) upon light irradiation, which makes it a potential additive able to change the reactivity of a conventional fuel. This paper presents the development of a detailed chemical kinetic model for the low-temperature ...

Three novel thermally activated delayed fluorescence (TADF) emitters, named MCZ-B-DTM, MCZ-P2-DTM and MCZ-P3-DTM are designed and synthesized for fabricating blue emission devices. The position of nitrogen atom in pyridine ring is varied relative to the donor unit and the presence of CH⋯N hydrog...

The synthesis of halogenated and arylated 1H-pyridin-2-ones starting from pyridinium N-(pyridin-2-yl)aminides is described. The synthetic pathway involves the reaction of pyridinium N-(5-bromopyridin-2-yl)aminide, N-(3-bromo-5-chloropyridin-2-yl)aminide or N-(3,5-dibromopyridin-2-yl)aminide with...

Three structurally different amino acids (Leucine, phenyl alanine and methionine) were reacted with oleic acid and polyethylene glycol (600) to give three nonionic surfactants (S1, S2 and S3). The chemical structures of the prepared surfactants were confirmed by FT-IR and 1H, 13CNMR. The surface...

The n-propyl-(PBB), ethyl-(EBB), and methyl-(MBB) homologs of propallylonal (IPBB) were prepared. Using albino rats, the intraperitoneal ED50s and LD50s were determined, as well as PD50s against pentylenetetrazol. Effectiveness in developing tolerance and cross-tolerance against propallylonal by...

Clandestine synthesis of methamphetamine in Australia has predominantly started from pseudoephedrine extracted from over the counter cold and flu medications. However, recently introduced restrictions on the sale of these products have made pseudoephedrine much more difficult to obtain. As a res...

Both (R)- and (S)-2-N-methylamino-2,3-dimethylbutanamides have been prepared by the reductive benzylation of (R)- and (S)-2-amino-2,3-dimethylbutanamides, followed by reductive methylation and hydrogenolytic removal of the benzyl group. The reductive benzylation is chemoselective, and not accomp...

The large scale industrial manufacture of the nasal decongestant pseudoephedrine is typically carried out by the reductive amination of l-phenylacetylcarbinol (l-PAC), which in turn is produced via the biotransformation of benzaldehyde using yeast. In recent years there has been increasing legis...

The reduction of cis-α-nitrostilbene (cis-1) in acetonitrile occurs by initial formation of the radical anion followed by irreversible dimerization to give the dinitronate dianion (3), of 1,4-dinitro-1,2,3,4-tetraphenylbutane (2). The standard potential for the neutral/radical anion couple is −...

A colourimetric sensor capable of simultaneously measuring oxidative status (OS) in terms of the hazard produced by reactive oxygen species (ROS) and antioxidant activity (AOA) in regard to ROS-scavenging ability of antioxidant compounds was developed. The coloured cationic semi-quinone derivati...

N,N-dimethyl(carboethoxymethyl)-3-phthalimidopropylammonium chloride dihydrate (1) and N,N-dimethyl(carboxymethyl)-3-phthalimidopropylammonium hydrochloride (3) have been obtained in reaction of N,N-dimethyl-3-phthalimidopropylamine with ethyl chloroacetate and chloroacetic acid, respectively. N...

The stereochemical preferences of N-nitroso- and N-formyl-c-3,t-3-dimethyl-r-2,c-7-diphenyl-1,4-diazepan-5-ones 3 & 4, respectively, have been determined using 1D and 2D NMR spectral techniques. Interestingly, the N-nitroso compound 3 is found to prefer an equilibrium between alternate chair con...

N,N-Dimethyl-3-phthalimidopropylammonium acetate and hydrochloride have been characterized by X-ray diffraction, FT-IR, Raman and NMR spectroscopy. Also B3LYP and DFT calculations have been carried out. The optimized bond lengths, bond angles and torsion angles calculated by B3LYP/6-31G(d,p) app...

Three novel bioactive azo dyes were synthesized by a classical diazo-coupling method using sulfamethazine with three different N, N-dimethyl aniline derivatives as coupling components under appropriate experimental conditions. The structural features of the newly synthesized compounds were explo...