The effect of antibody on the reversible deactivation of the β-lactamase (penicillin amino-β-lactamhydrolase, EC 3.5.2.6) from Staphylococcus aureas has been studied using quinacillin and cephaloridine as substrates. The latter has been shown to exhibit the characteristics of an A-type substra...

Mice were examined for carcinogenic effects of 4-nitro and 4-hydroxylamino-quinoline 1-oxide derivatives which were substituted by an additional group or atom such as a methyl-, halogeno- or nitro-group. It became evident from the carcinogenicity-structure relationship that carcinogenesis of thi...

The N-oxide of 4-(1′-n-tridecyl)pyridine (TDPNO) is a novel agent which could be used for the separation of Cr(VI) from aqueous solutions of sulphuric acid. The distribution constants (KD) of TDPNO in the systems: toluene/0.5 M (Na, H)2SO4 and toluene-n-heptane (3:1) mixture/0.5 M (Na, H)2SO4, ...

Iron(II) perchlorate in an H2O-H2O2-CH3CN mixture was used to efficiently carry out CH bond activations of benzene to form phenol and/or hydroquinone, and of toluene to form benzaldehyde, benzyl alcohol, o-cresol, p-cresol, and/or methyl-p-benzoquinone. The reactions were facilely tuned and cont...

Chiral 2-bromopropionates are widely used as raw materials or intermediates for synthesis of chiral pesticides and medicines with high biological activities. Enantioseparation of 2-bromopropionates is crucial for evaluating the optical purity of chiral 2-bromopropionates. In this study, the enan...

Zeolites with different framework topology (SSZ-33, SSZ-35 and SSZ-42) were investigated in alkylation of phenol, m-cresol and p-cresol, and acylation of 2-methoxynaphthalene. Their catalytic behavior was compared with commercial zeolites BEA, USY, MOR and ZSM-5. Borosilicates SSZ-33 and SSZ-42 ...

Optically pure regioisomer of (S)-methyl 4-methyl-5-oxo-5-[1H-pyrazol-1-yl)pentanoate ((S)-2) and (R)-methyl 2-methyl-5-oxo-5-[1H-pyrazol-1-yl)pentanoate ((R)-3) were prepared from regioselective methanolysis of (S)-2-methylglutaric dipyrazolide ((S)-1) and (R)-2-methylglutaric dipyrazolide ((R)...

Deprotection of oximes, phenylhydrazones, p-nitrophenylhydrazones, semicarbazones and tosylhydrazones to their parent aldehydes and ketones was efficiently achieved by using sodium nitrite in the presence of Amberlyst 15. The reactions were performed in dioxane in high yields at 70 °C. It is ob...

The selective oxidation of ethylbenzene and cyclohexene to acetophenone and 2-cyclohexene-1-one using N-hydroxyphthalimide (NHPI) under oxygen atmosphere in the presence of an SiO2/Al2O3-supported cobalt catalyst occurs with conversions of 83 and 75% and selectivities of 99%. The supported cobal...

Currently fielded treatments for nerve agent intoxication include atropine, an acetylcholine receptor antagonist, and pralidoxime (2PAM), a small molecule reactivator of acetylcholinesterase (AChE). 2PAM reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on...

Eu(III) doped Zn2Al-LDH intercalated with cinnamate anions with different C9H7O2-/M3+ molar ratios were synthesized by different anion-exchange methods. The XRD patterns indicate the formation of hydrotalcite-like compounds. UV–VIS absorption spectra show that the hybrid materials obtained have...

This paper reports the preparation of green pesticides based on nano-hybrids composed of a Layered Double Hydroxide (LDH) with cinnamate anion. The dispersion into a pectin matrix was obtained using high energy ball milling in wet conditions. Structure and physical properties of the fillers and ...

An organic UV absorber, cinnamic acid, was intercalated into the interlayer gallery of layered yttrium hydroxynitrate (LYH) via the anion-exchange reaction. The complete replacement of interlayer nitrate by cinnamate was confirmed by thermogravimetric analysis of the obtained intercalation compo...

New polymer nanocomposite based on poly (vinyl cinnamate) (PVCin) with zinc oxide (ZnO) was synthesized by in situ polymerization of vinyl cinnamate with different concentrations of ZnO nanoparticles. The composite was characterized through FT-IR, FT-Raman, UV spectroscopy, XRD, HRTEM, FE-SEM, D...

Urea and butyrylcholine chloride (BuChCl) biosensors were prepared by adsorption of urease and butyrylcholinesterase (BuChE) on heat-treated zeolite Beta crystals, which were incorporated into membranes deposited on ion-selective field-effect transistor (ISFET) surfaces. The responses, stabiliti...

A butyrylcholine-hydrolyzing enzyme (EC 3.1.1.-) of Pseudomonas polycolor IFO 3918 was purified approximately 9270-fold with a recovery of 9.9% by use of chromatographic techniques. The enzyme preparation appeared to be homogeneous when subjected to electrophoretic and ultracentrifugational anal...

BackgroundOlive phenols are widely consumed in the Mediterranean diet and can be detected in human plasma. Here, the capacity of olive phenols and plasma metabolites to inhibit lipid and protein oxidations is investigated in two plasma models.

Neuropathic pain arises from the injury of nervous system. The condition is extremely difficult to be treated due to the ineffectiveness and presence of various adverse effects of the currently available drugs. In the present study, we investigated the antiallodynic and antihyperlagesic properti...

Previous studies have shown that testes-specific protease 50 (TSP50), a pro-oncogene overexpressed in many types of tumors, could promote cell proliferation, invasion, tumorigenesis, and tumor metastasis, suggesting that it is a potential cancer therapeutic target in drug discovery. Here, a luci...

Cardamonin is a natural chalcone that has been shown to exhibit high anticancer activity. In an attempt to discover analogues of cardamonin with enhanced anticancer activity, 19 analogues were synthesized and tested against A549 and HK1 cell lines. Results of the MTS cell viability assay showed ...