Glycine (0.1–10 mM) caused a dose-dependent increase in the removal of 5 mM [1-14Clglutamine by isolated rat-liver cells; at low concentrations of glycine, an increase in the formation of 14CO2, urea and glucose from glutamine occurred. At 2–10 mM, glycine also caused an accumulation of ammoni...

Résumé1.1. L'incorporation de la glycine dans les protoplastes de Micrococcus lysodeikticus est étroitement liée à la respiration du système. Les deux phénom`enes dépendent de la même façon de la concentration en bactéries lysées et atteignent un maximum pour les suspensions cont...

Activity of glycine decarboxylase decreased by 60–70% after the isolated pea leaf mitochondria were aged for 5 h in the absence of glycine and was completely lost after 24 h. The reverse reaction, i.e., production of glycine from serine, ammonium, dihydrolipoate, and bicarbonate, was also inhib...

A study has been conducted to measure the transfer of label from [1-14C]glucose, [3,4-14C]glucose and [1,5-14C]citrate to glycine, serine and other metabolically active amino acids in the central nervous system of the rat.Our results indicate that in vivo carbon atoms for the synthesis of glycin...

The aminoacyl analysis of endotoxic lipopolysaccharides (LPS) isolated from several bacteria revealed essential amounts of glycine, among the inherent LPS components. Significant amounts of the glycine was detected in lipopolysaccharides isolated from over 30 strains of Escherichia, Salmonella, ...

The synthesis of poly(L-tyrosyl-e-N-L-glutamyl-L-lysyl-L-alanylglycyl)glycine methyl ester (I) is described. This material neither crossreacts with antibodies to poly(L-tyrosyl-L-glutamyl-L-alanylglycyl)glycine-1-14C ethyl ester nor inhibits the precipitin reaction between these antibodies and t...

A β-ray track radioautographic study of the in vitro incorporation of glycine-1-14C in rabbit blood containing a high percentage of reticulocytes has been accomplished. Whereas the reticulocytes incorporate appreciable amounts of the amino acid, the mature erythrocytes have an activity not sign...

The 1H-1,2,3-triazole-originated derivatives of willardiine were obtained by: (i) construction of the 1H-1,2,3-triazole ring in 1,3-dipolar cycloaddition of the uracil-derived azides and the carboxylate-bearing alkynes or α-acylphosphorus ylide, or (ii) N-alkylation of the uracil derivative wit...

The interactive effects of elevated atmospheric CO2 concentration ([CO2]) (700 μmol l−1) and increased soil temperature (+2.4 °C) on source-sink amino acid carbon (C) and nitrogen (N) dynamics and their relations to the concentration of grain protein components in winter wheat were investigate...

BLAST analysis of the 16S rRNA gene sequence for the newly isolated bacterium, revealed significant identity (99.5%) with Bacillus sonorensis [Ijadi Bajestani, M., et al., International Journal of Biological Macromolecules, 2017. 96: p. 100–110]. According to the literature review for closely r...

The inter-and intra-crystalline fractions of the topshell Phorcus lineatus recovered from modern specimens and shells from archaeological sites in Northern Spain covering Neolithic, Mesolithic, and Upper Magdalenian periods were examined for amino acid composition and racemisation over time. The...

Copper-mediated Michael addition of ethyl bromodifluoroacetate to N-protected α,β-unsaturated α-amino acid esters was applied for straightforward synthesis of γ,γ-difluorinated analogues of glutamic acid (compound 1) and glutamine (compound 10). Moreover, a proline-based, sterically constra...

Jasmonic acid (JA) is an important phytohormone associated in defense responses against stress. Crop plants experience heavy metal toxicity and needs to be explored to enhance the crop production. Lead (Pb) is one of the dangerous heavy metal that pollutes soil and water bodies and is released f...

Several methods for chemical modification of nanocrystalline cellulose by poly(glutamic acid) were tested. The best one was based on partial oxidation of cellulose followed by reaction of the resulting aldehyde groups with terminal amino groups of poly(glutamic acid). The modified cellulose fill...

A series of 2-(trifluoromethyl)-1H-benzimidazole derivatives (1a–1i) were synthesized via Phillips cyclocondensation of a substituted 1,2-phenylenediamine and trifluoroacetic acid. The synthesized compounds were evaluated in vitro against various protozoan parasites: Giardia intestinalis, Entam...

We previously disclosed the discovery of 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone (3) as a novel class of dopamine transporter (DAT) inhibitors and showed that (±)-3 has a significant functional antagonism against cocaine in vitro. Our previous preliminary structu...

Diabetes is considered as the most common metabolic disease affecting millions of people all around the world. Use of natural herbal medicines can be effective in treating diabetes. Zingerone (4-(4-hydroxy-3-methylphenyl) butan-2-one) a polyphenolic alkanone extracted from ginger has a broad spe...

In this work, the vibrational spectral analysis of 3,5-diamino-6-chloro-N-(diaminomethylene)pyrazine-2-carboxamide(3DCNDPC) was carried out using FT-Raman and FT-IR spectroscopy in the range 4000–50 cm−1 and 4000–500 cm−1 respectively. The experimental spectra were recorded in the solid phase....

A new series of N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides 23–48 have been synthesized as potential anticancer agents. All compounds were screened for their cytotoxic activity against six human tumor cell lines. The selected compounds 23–27, 30, 31, 33, 35, 38, 42, 45, an...

Despite the lack of knowledge of the effects of electronic cigarettes (e-cigarettes, e-cigs) on public health, they have been proposed as a part of smoking cessation efforts. Recently, several basic scientific studies have pointed out how e-cigs can generate carcinogens, such as e-cig liquid the...