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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name 4-(Aminomethyl)benzoic acid CAS No.

4-(Aminomethyl)benzoic acid

Cas:56-91-7

Min.Order:1 Gram

FOB Price: $8.0

Type:Lab/Research institutions

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Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

99% up GMP DMF 4-(Aminomethyl)benzoic acid/ Aminomethylbenzoic acid 56-91-7

Cas:56-91-7

Min.Order:1 Kilogram

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Characteristics White crystalline powder Complies Chlorides ≤240ppm

High purity 4-(Aminomethyl)benzoic acid with high quality and best price cas:56-91-7

Cas:56-91-7

Min.Order:1 Kilogram

FOB Price: $40.0 / 80.0

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Pamba supplier in China

Cas:56-91-7

Min.Order:0 Metric Ton

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Aminomethybenzoic acid injection 5ml/50mg;10ml/100mg

Cas:56-91-7

Min.Order:1 Gram

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Hangzhou Think Chemical Co. Ltd

4-(Aminomethyl)benzoic acid CAS:56-91-7 p-(Aminomethyl)benzoic acid HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experienc

Good quantity 4-(Aminomethyl)benzoic acid CAS:56-91-7 with competitive price

Cas:56-91-7

Min.Order:25 Kilogram

FOB Price: $80.0

Type:Other

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Pamba

Cas:56-91-7

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Wuhan Fortuna Chemical Co.,Ltd

CAS RN.: 56-91-7 EINECS: 200-297-9 Molecular Weight:

4-(Aminomethyl)benzoic acid 56-91-7

Cas:56-91-7

Min.Order:10 Kilogram

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 56-91-7 4-(Aminomethyl)benzoic acid Manufacturer

Cas:56-91-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

P-Aminomethylbenzoic Acid

Cas:56-91-7

Min.Order:1 Metric Ton

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

4-(Aminomethyl)benzoic acid 56-91-7 /manufacturer/low price/high quality/in stock

Cas:56-91-7

Min.Order:1 Kilogram

FOB Price: $15.0 / 16.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-(Aminomethyl)-benzoic acid

Cas:56-91-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

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Hubei DiBo chemical co., LTD

Name:Aminomethylbenzoic acid CAS no:56-91-7 Grade:Organic synthesis intermediate Molecular formula: C8H9NO2 Molecular weight: 151.16 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability

Aminomethylbenzoic acid/cas:56-91-7/Aminomethylbenzoic acid material

Cas:56-91-7

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Leader Biochemical Group

About Product Technical Details

China Largest factory Manufacturer Supply High Quality 4-(Aminomethyl)benzoic acid CAS 56-91-7

Cas:56-91-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

High quality ,lower price 4-(Aminomethyl)benzoic acid Basic information Product Name: 4-(Aminomethyl)benzoic acid Synonyms: H-4-AMB-OH;H-(4)AMBZ-OH;LABOTEST-BB LT00053184;AMINOMETHYL B

4-(Aminomethyl)benzoic acid

Cas:56-91-7

Min.Order:1 Metric Ton

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

4- (Aminomethyl) Benzoic Acid CAS 56-91-7

Cas:56-91-7

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Hot selling CAS 56-91-7 with best price

Cas:56-91-7

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

4-(Aminomethyl)benzoic acid 56-91-7

Cas:56-91-7

Min.Order:10 Kilogram

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powder 2. Fact

4-(Aminomethyl)benzoic acidCAS56-91-7

Cas:56-91-7

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 4-(Aminomethyl)benzoic acid Synonyms: Aminomethylbenzoic acid CAS:56-91-7 Appearance:White Powder Storage:Store in cool and dry place, away from sun light. Package:25kg Application: organic synthesis Transportation:By sea or by air Port:Qing

4-(Aminomethyl)benzoic acid

Cas:56-91-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:White powder Storage:R.T Package:25kg/drum Application:Pharmaceutical intermediates Transportation:Express/Sea/Air Port:Any port in China

Intermediate 4-(Aminomethyl)benzoic acid cas 56-91-7

Cas:56-91-7

Min.Order:25 Kilogram

Negotiable

Type:Lab/Research institutions

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HANWAYS CHEMPHARM CO.,LIMITED

1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: :4-(Aminomethyl)benzoic acid Structure: Formula: C8H9NO2 Molecular Weight : 151.16 Synonyms: AMINOMETHYL BENZOIC ACID;H-4-AMB-OH;H-(4)AMBZ-OH;LABOTEST-BB

Factory Supply 4-(Aminomethyl)benzoic acid

Cas:56-91-7

Min.Order:1 Kilogram

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Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzoic acid, 4-(aminomethyl)- 56-91-7

Cas:56-91-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Kanamycin sulfate Antibiotics.56-91-7

Cas:56-91-7

Min.Order:1 Kilogram

FOB Price: $80.0 / 85.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

4-(Aminomethyl)benzoic acid CAS:56-91-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

4-(Aminomethyl)benzoic acid CAS:56-91-7

Cas:56-91-7

Min.Order:1 Gram

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Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzoic acid, 4-(aminomethyl)-

Cas:56-91-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Benzoic acid, 4-(aminomethyl)-/ LIDE PHARMA- Factory supply / Best price

Cas:56-91-7

Min.Order:0

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Type:Lab/Research institutions

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Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

4-aminomethylbenzoic acid CAS 56-91-7

Cas:56-91-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe,

Aminomethylbenzoic acid cas 56-91-7 4-(Aminomethyl)benzoic acid

Cas:56-91-7

Min.Order:1 Kilogram

FOB Price: $80.0 / 100.0

Type:Trading Company

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Shanghai Terui OP New Material Technology Co., Ltd.

We have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful

High Quality Product China Supplier DDP 4-(Aminomethyl)benzoic acid CAS 56-91-7

Cas:56-91-7

Min.Order:1 Kilogram

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Type:Trading Company

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Synthetic route

p-Toluic acid
99-94-5

p-Toluic acid

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
With ammonium peroxydisulfate; 2,2'-azobis-(2,4-dimethylvaleronitrile); hydrogen bromide In tetrachloromethane at 45℃; for 15h; Solvent; Reagent/catalyst; Temperature;98%
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 2 h / 80 °C
2: triethylamine; potassium carbonate / tetrachloromethane / 4 h / 25 °C
View Scheme
4-(hydroxyiminomethyl)benzoic acid methyl ester
53148-13-3

4-(hydroxyiminomethyl)benzoic acid methyl ester

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
Stage #1: 4-(hydroxyiminomethyl)benzoic acid methyl ester With water; hydrogen; sodium hydroxide; 5%-palladium/activated carbon at 20℃; under 7355.72 Torr; for 3.5h;
Stage #2: With hydrogenchloride In water pH=7;
95.8%
With water; hydrogen; sodium hydroxide; 5%-palladium/activated carbon at 20℃; under 7355.72 Torr; for 3.5h; Conversion of starting material;
4-bromomethylbenzoic Acid
6232-88-8

4-bromomethylbenzoic Acid

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
With potassium carbonate; triethylamine In tetrachloromethane at 25℃; for 4h; Temperature;95.32%
With ammonium hydroxide
ethyl 4-(aminomethyl)benzoate
366-84-7

ethyl 4-(aminomethyl)benzoate

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
With sulfuric acid at 80℃; for 1h; Temperature;91%
With sulfuric acid at 80℃; for 1h;78.35%
methyl 4-(aminomethyl)benzoate
18469-52-8

methyl 4-(aminomethyl)benzoate

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
With sulfuric acid at 50℃; for 1.5h;87%
With sodium hydroxide; water
4-cyanobenzoic Acid
619-65-8

4-cyanobenzoic Acid

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
With hydrogen; Raney Nickel In methanol for 16h;84%
With ammonium hydroxide; nickel Hydrogenation;
In ethanol
4-cyanobenzoic acid methyl ester
1129-35-7

4-cyanobenzoic acid methyl ester

A

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

B

methyl 4-(aminomethyl)benzoate
18469-52-8

methyl 4-(aminomethyl)benzoate

C

methyl 4-((4-(aminomethyl)benzamido)methyl)benzoate

methyl 4-((4-(aminomethyl)benzamido)methyl)benzoate

Conditions
ConditionsYield
With ammonia; nickelA 21.9%
B 44.3%
C 6.2%
p-carboxybenzaldehyde oxime
3477-93-8

p-carboxybenzaldehyde oxime

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
With palladium on activated charcoal; ethanol Hydrogenation;
4-[(2-carboxy-benzoylamino)-methyl]-benzoic acid
303795-50-8

4-[(2-carboxy-benzoylamino)-methyl]-benzoic acid

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
With hydrogenchloride at 200℃; im Druckrohr;
hexamethylenetetramine
100-97-0

hexamethylenetetramine

4-iodomethyl-benzoic acid ethyl ester

4-iodomethyl-benzoic acid ethyl ester

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
With hydrogenchloride; chloroform
hydrogenchloride
7647-01-0

hydrogenchloride

4-[(2-carboxy-benzoylamino)-methyl]-benzoic acid
303795-50-8

4-[(2-carboxy-benzoylamino)-methyl]-benzoic acid

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
at 200℃;
4-Carboxybenzaldehyde
619-66-9

4-Carboxybenzaldehyde

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
Stage #1: 4-Carboxybenzaldehyde With Rink resin; trimethyl orthoformate at 25℃; for 2h;
Stage #2: With lithium borohydride In tetrahydrofuran at 65℃; for 5h;
Stage #3: With trifluoroacetic acid In dichloromethane at 25℃;
4-amino-benzoic acid
150-13-0

4-amino-benzoic acid

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aq. NaOH solution; nickel (II)-sulfate; water / Diazotization.weiteres Reagens: wss. Salzsaeure; anschliessendes Erwaermen
2: Raney nickel; aqueous ammonia / Hydrogenation
View Scheme
4-cyanobenzyl bromide
17201-43-3

4-cyanobenzyl bromide

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous hydrochloric acid
2: aqueous ammonia
View Scheme
4-aminobenzyl cyanide
10406-25-4

4-aminobenzyl cyanide

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
With sodium hydroxide; sulfuric acid
methyl 4-formylbenzoate
1571-08-0

methyl 4-formylbenzoate

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: hydroxylamine hydrochloride / water; methanol / 2 h / 25 - 35 °C
1.2: pH 7.5 - 8
2.1: hydrogen; sodium hydroxide; water / 5%-palladium/activated carbon / 3.5 h / 20 °C / 7355.72 Torr
2.2: pH 7
View Scheme
Multi-step reaction with 2 steps
1.1: hydroxylamine hydrochloride / 5%-palladium/activated carbon / water; methanol / 2 h / 25 - 35 °C
1.2: pH 7.5 - 8
2.1: hydrogen; sodium hydroxide; water / 5%-palladium/activated carbon / 3.5 h / 20 °C / 7355.72 Torr
View Scheme
4-(hydroxyiminomethyl)benzoic acid methyl ester
53148-13-3

4-(hydroxyiminomethyl)benzoic acid methyl ester

A

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

B

p-carboxybenzaldehyde oxime
3477-93-8

p-carboxybenzaldehyde oxime

Conditions
ConditionsYield
With hydrogen; sodium hydroxide; 5%-palladium/activated carbon In water at 20℃; under 7355.72 Torr; for 8.5h; Conversion of starting material;
(S)-1-phenyl-ethylamine
2627-86-3

(S)-1-phenyl-ethylamine

4-Carboxybenzaldehyde
619-66-9

4-Carboxybenzaldehyde

A

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

B

acetophenone
98-86-2

acetophenone

Conditions
ConditionsYield
With pyridoxal 5'-phosphate; recombinant ω-transaminase from Burkholderia vietnamiensis G4 In aq. phosphate buffer at 37℃; for 0.0833333h; pH=7.4; Enzymatic reaction;
monomethyl monopotassium terephthalate
42967-55-5

monomethyl monopotassium terephthalate

A

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

B

methyl 4-(aminomethyl)benzoate
18469-52-8

methyl 4-(aminomethyl)benzoate

C

methyl 4-((4-(aminomethyl)benzamido)methyl)benzoate

methyl 4-((4-(aminomethyl)benzamido)methyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: bis(trichloromethyl) carbonate / toluene; N,N-dimethyl-formamide / Reflux
2: ammonia / water / 1.5 h / 0 - 20 °C
3: acetic anhydride / Reflux
4: ammonia; nickel
View Scheme
1,4-benzenedicarboxylic acid dimethyl ester
120-61-6

1,4-benzenedicarboxylic acid dimethyl ester

A

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

B

methyl 4-(aminomethyl)benzoate
18469-52-8

methyl 4-(aminomethyl)benzoate

C

methyl 4-((4-(aminomethyl)benzamido)methyl)benzoate

methyl 4-((4-(aminomethyl)benzamido)methyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: potassium hydroxide / methanol / 45 - 50 °C
2: bis(trichloromethyl) carbonate / toluene; N,N-dimethyl-formamide / Reflux
3: ammonia / water / 1.5 h / 0 - 20 °C
4: acetic anhydride / Reflux
5: ammonia; nickel
View Scheme
Multi-step reaction with 5 steps
1: potassium hydroxide / methanol; toluene / 5.5 h / 45 - 50 °C
2: bis(trichloromethyl) carbonate / toluene; N,N-dimethyl-formamide / Reflux
3: ammonia / water / 1.5 h / 0 - 20 °C
4: acetic anhydride / Reflux
5: ammonia; nickel
View Scheme
4-Methoxycarbonylbenzoyl chloride
7377-26-6

4-Methoxycarbonylbenzoyl chloride

A

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

B

methyl 4-(aminomethyl)benzoate
18469-52-8

methyl 4-(aminomethyl)benzoate

C

methyl 4-((4-(aminomethyl)benzamido)methyl)benzoate

methyl 4-((4-(aminomethyl)benzamido)methyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ammonia / water / 1.5 h / 0 - 20 °C
2: acetic anhydride / Reflux
3: ammonia; nickel
View Scheme
methyl-4-carbamoylbenzoate
6757-31-9

methyl-4-carbamoylbenzoate

A

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

B

methyl 4-(aminomethyl)benzoate
18469-52-8

methyl 4-(aminomethyl)benzoate

C

methyl 4-((4-(aminomethyl)benzamido)methyl)benzoate

methyl 4-((4-(aminomethyl)benzamido)methyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetic anhydride / Reflux
2: ammonia; nickel
View Scheme
p-methyloxycarbonylbenzyl chloride
34040-64-7

p-methyloxycarbonylbenzyl chloride

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triethylamine; 5-methyl-1,3,4-thiadiazol-2-amine / ethanol; water / 0.5 h / 100 °C
2: sulfuric acid / 1.5 h / 50 °C
View Scheme
ethyl 4-chloromethylbenzoate
1201-90-7

ethyl 4-chloromethylbenzoate

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triethylamine; 5-methyl-1,3,4-thiadiazol-2-amine / ethanol; water / 1.5 h / 80 °C
2: sulfuric acid / 1 h / 80 °C
View Scheme
phthalic anhydride
85-44-9

phthalic anhydride

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: water; sodium hydroxide / 3 h / 80 - 150 °C
2: ammonium hydroxide / 1 h / 180 °C
3: aluminum (III) chloride / diethyl ether / 1 h / 40 °C
4: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 2 h / 80 °C
5: triethylamine; potassium carbonate / tetrachloromethane / 4 h / 25 °C
View Scheme
benzoic acid
65-85-0

benzoic acid

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aluminum (III) chloride / diethyl ether / 1 h / 40 °C
2: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 2 h / 80 °C
3: triethylamine; potassium carbonate / tetrachloromethane / 4 h / 25 °C
View Scheme
benzene-1,2-dicarboxylic acid
88-99-3

benzene-1,2-dicarboxylic acid

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: ammonium hydroxide / 1 h / 180 °C
2: aluminum (III) chloride / diethyl ether / 1 h / 40 °C
3: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 2 h / 80 °C
4: triethylamine; potassium carbonate / tetrachloromethane / 4 h / 25 °C
View Scheme
p-(chloromethyl)benzoic acid
1642-81-5

p-(chloromethyl)benzoic acid

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

Conditions
ConditionsYield
Stage #1: p-(chloromethyl)benzoic acid With hexamethylenetetramine In methanol; water for 1h;
Stage #2: With ammonia In methanol; water at 50 - 60℃;
methanol
67-56-1

methanol

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

methyl 4-(aminomethyl)benzoate hydrochloride
6232-11-7

methyl 4-(aminomethyl)benzoate hydrochloride

Conditions
ConditionsYield
With thionyl chloride at 0 - 20℃; for 24h;100%
With thionyl chloride at 20℃; for 96h;99%
With thionyl chloride at 0℃; for 24h; Reflux;99%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

lactoseamidemethylbenzoic acid
173543-54-9

lactoseamidemethylbenzoic acid

Conditions
ConditionsYield
In dimethyl sulfoxide at 130 - 150℃; for 3h;100%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

(fluorenylmethoxy)carbonyl chloride
28920-43-6

(fluorenylmethoxy)carbonyl chloride

N-(9-fluorenylmethyloxycarbonyl)-4-(aminomethyl)benzoic acid
164470-64-8

N-(9-fluorenylmethyloxycarbonyl)-4-(aminomethyl)benzoic acid

Conditions
ConditionsYield
With sodium carbonate In 1,4-dioxane; water100%
With sodium carbonate In 1,4-dioxane; water at 20℃; for 12h;90%
With sodium hydrogencarbonate In 1,4-dioxane at 0℃; for 3h;68.1%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

4-{[bis-(2-methoxycarbonyl-ethyl)-amino]-methyl}-benzoic acid

4-{[bis-(2-methoxycarbonyl-ethyl)-amino]-methyl}-benzoic acid

Conditions
ConditionsYield
In methanol at 20℃; for 12h;100%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

isobutyryl chloride
79-30-1

isobutyryl chloride

4-[(isobutyrylamino)methyl]benzoic acid
908495-37-4

4-[(isobutyrylamino)methyl]benzoic acid

Conditions
ConditionsYield
Stage #1: p-aminomethylbenzoic acid; isobutyryl chloride With triethylamine In dichloromethane for 132h;
Stage #2: With hydrogenchloride In dichloromethane; water; ethyl acetate pH=1;
100%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

isatoic anhydride
118-48-9

isatoic anhydride

4-((2-aminobenzamido)methyl)benzoic acid
503039-57-4

4-((2-aminobenzamido)methyl)benzoic acid

Conditions
ConditionsYield
With triethylamine In water at 40℃; for 3h;100%
With triethylamine In water72%
With triethylamine In water72%
With dmap; triethylamine In pyridine; N,N-dimethyl-formamide at 80℃; for 16h;70.7%
In water at 20℃; for 2h; Green chemistry;
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

ethanol
64-17-5

ethanol

p-(Aminometyl)benzoic acid ethyl ester hydrochloride
6232-12-8

p-(Aminometyl)benzoic acid ethyl ester hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water Reflux;100%
With thionyl chloride at 0℃; for 3h; Heating / reflux;
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

phenyl isothiocyanate
103-72-0

phenyl isothiocyanate

4-[(3-phenyl-tioureido)methyl]benzoic acid
356773-26-7

4-[(3-phenyl-tioureido)methyl]benzoic acid

Conditions
ConditionsYield
In ethanol for 24h; Reflux;100%
In ethanol Reflux;
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

tri-tert-butyl 2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
819869-77-7

tri-tert-butyl 2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate

C36H59N5O9

C36H59N5O9

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h;100%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
82911-69-1

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

N-(9-fluorenylmethyloxycarbonyl)-4-(aminomethyl)benzoic acid
164470-64-8

N-(9-fluorenylmethyloxycarbonyl)-4-(aminomethyl)benzoic acid

Conditions
ConditionsYield
With sodium carbonate In 1,4-dioxane at 40℃; for 12h;99%
With sodium hydrogencarbonate In tetrahydrofuran at 20℃; for 3.8h;93.5%
With sodium hydrogencarbonate In 1,4-dioxane; water at 20℃; for 2h; Acylation;77.7%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

3-Bromobenzenesulfonyl chloride
2905-24-0

3-Bromobenzenesulfonyl chloride

4-{[(3-bromophenyl)sulfonamido]methyl}benzoic acid

4-{[(3-bromophenyl)sulfonamido]methyl}benzoic acid

Conditions
ConditionsYield
With Sodium borate In water at 20℃; for 16.0833h; Sonication;99%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

methyl 4-(aminomethyl)benzoate hydrochloride
6232-11-7

methyl 4-(aminomethyl)benzoate hydrochloride

Conditions
ConditionsYield
With methanol; thionyl chloride Reflux;98.3%
With thionyl chloride In methanol at 20℃; for 16h;97%
With hydrogenchloride In methanol
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

4-(tert-Butoxycarbonylaminomethyl)benzoic acid
33233-67-9

4-(tert-Butoxycarbonylaminomethyl)benzoic acid

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane at 0 - 20℃; for 24h;98%
Stage #1: p-aminomethylbenzoic acid; di-tert-butyl dicarbonate With sodium hydrogencarbonate In tetrahydrofuran; water for 16h; pH=~ 6;
Stage #2: With hydrogenchloride; water In tetrahydrofuran pH=~ 3;
97%
Stage #1: p-aminomethylbenzoic acid; di-tert-butyl dicarbonate With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; for 16h; pH=6;
Stage #2: With hydrogenchloride; water In water pH=3;
97%
3-hydroxymethylpyridin
100-55-0

3-hydroxymethylpyridin

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

4-benzoic acid
241809-79-0

4-benzoic acid

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide; sodium chloride; 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide98%
Stage #1: 3-hydroxymethylpyridin With 1,1'-carbonyldiimidazole In tetrahydrofuran at 10 - 20℃; for 1h;
Stage #2: p-aminomethylbenzoic acid With 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine In tetrahydrofuran at 20℃; for 5h;
Stage #3: With hydrogenchloride; water pH=5;
91%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

4-fluoro-3-chlorobenzenesulfonyl chloride
91170-93-3

4-fluoro-3-chlorobenzenesulfonyl chloride

4-{[(3-chloro-4-fluorophenyl)sulfonamido]methyl}benzoic acid
690646-06-1

4-{[(3-chloro-4-fluorophenyl)sulfonamido]methyl}benzoic acid

Conditions
ConditionsYield
With borax In water at 20℃; for 4h; Sonication;98%
With Sodium borate In water at 20℃; for 4.08333h; Sonication;98%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

4-hydroxymethyl-benzylamine
39895-56-2

4-hydroxymethyl-benzylamine

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; Reflux;97%
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 12h; Reflux;97%
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; Inert atmosphere; Reflux;65%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

benzyl chloroformate
501-53-1

benzyl chloroformate

4-((benzyloxycarbonylamino)methyl)benzoic acid
58933-52-1

4-((benzyloxycarbonylamino)methyl)benzoic acid

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane; water at 0 - 20℃; for 16h;97%
In water at 20℃; for 16h;95%
In water at 0 - 20℃;95%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

trifluoroacetic anhydride
407-25-0

trifluoroacetic anhydride

4-[[(2,2,2-trifluoroacetyl)amino]methyl]benzoic acid
130029-61-7

4-[[(2,2,2-trifluoroacetyl)amino]methyl]benzoic acid

Conditions
ConditionsYield
at 0 - 20℃; for 2h;97%
for 2h;93%
at 25℃; for 2h;88%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

9-Chloroacridine
1207-69-8

9-Chloroacridine

4-((acridin-9-amino)methyl)benzoic acid
1211776-25-8

4-((acridin-9-amino)methyl)benzoic acid

Conditions
ConditionsYield
In 2-ethoxy-ethanol at 90 - 100℃;97%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

phenyl isocyanate
103-71-9

phenyl isocyanate

4-<<<(phenylamino)carbonyl>amino>methyl>benzoic acid

4-<<<(phenylamino)carbonyl>amino>methyl>benzoic acid

Conditions
ConditionsYield
With sodium hydroxide at 23℃; for 1h;96%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

benzene-1,2-dicarboxylic acid
88-99-3

benzene-1,2-dicarboxylic acid

4-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]benzoic acid
227598-41-6

4-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]benzoic acid

Conditions
ConditionsYield
In acetonitrile at 180℃; for 0.5h; Reagent/catalyst; Temperature; Inert atmosphere; Sealed tube; Microwave irradiation;96%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

3-((3,5-bis(trifluoromethyl)phenyl)amino)-4-ethoxycyclobut-3-ene-1,2-dione
1233032-09-1

3-((3,5-bis(trifluoromethyl)phenyl)amino)-4-ethoxycyclobut-3-ene-1,2-dione

3,5-bis[trifluoromethyl]phenyl squaramide-4-aminomethyl benzoic acid

3,5-bis[trifluoromethyl]phenyl squaramide-4-aminomethyl benzoic acid

Conditions
ConditionsYield
With sodium carbonate In ethanol at 135℃; for 0.583333h; Microwave irradiation; Sealed tube;96%
3-Sulfolene
77-79-2

3-Sulfolene

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

4-(N-(3-tetrahydrothiophenyl-1,1-dioxide)aminomethyl)benzoic acid

4-(N-(3-tetrahydrothiophenyl-1,1-dioxide)aminomethyl)benzoic acid

Conditions
ConditionsYield
With potassium hydroxide In water at 55℃; for 23h;95%
methanol
67-56-1

methanol

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

methyl 4-(aminomethyl)benzoate
18469-52-8

methyl 4-(aminomethyl)benzoate

Conditions
ConditionsYield
With hydrogenchloride In water at 85℃; for 16h; Fischer–Speier Esterification;95%
With thionyl chloride for 6h; Heating / reflux;92%
With sulfuric acid for 6h; Reflux;92%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

N,N'-bis( tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine
152120-54-2, 862686-58-6, 1143572-00-2

N,N'-bis( tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine

N,N'-bis-tert-butoxycarbonyl-4-guanidinomethyl-benzoic acid
246224-53-3

N,N'-bis-tert-butoxycarbonyl-4-guanidinomethyl-benzoic acid

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran Heating;95%
morpholine
110-91-8

morpholine

p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

4-fluorophthalic anhydride
319-03-9

4-fluorophthalic anhydride

4-{[5-(morpholin-4-yl)-1,3-dioxoisoindol-2-yl]methyl}benzoic acid
1613391-57-3

4-{[5-(morpholin-4-yl)-1,3-dioxoisoindol-2-yl]methyl}benzoic acid

Conditions
ConditionsYield
In 1-methyl-pyrrolidin-2-one at 200℃; for 1.25h; Inert atmosphere; Microwave irradiation;95%
p-aminomethylbenzoic acid
56-91-7

p-aminomethylbenzoic acid

4-fluorophenyl isothiocyanate
1544-68-9

4-fluorophenyl isothiocyanate

4-{[3-(4-fluorophenyl)thioureido]methyl}benzoic acid

4-{[3-(4-fluorophenyl)thioureido]methyl}benzoic acid

Conditions
ConditionsYield
In ethanol for 24h; Reflux;95%
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