2-Methylcyclohexanol supplier

Name
2-Methylcyclohexanol
EINECS 209-512-0
CAS No. 583-59-5
Article Data266
CAS DataBase
Density 0.925 g/cm³
Solubility Slightly soluble in water
Melting Point -38 °C
Formula C₇H₁₄O
Boiling Point 170.322 °C at 760 mmHg
Molecular Weight 114.188
Flash Point 58.889 °C
Transport Information UN 2617 3/PG 3
Appearance Colourless viscous liquid with an aromatic odour
Safety 24/25
Risk Codes 20
Molecular Structure
Hazard Symbols Xn
Synonyms 1-Methyl-2-cyclohexanol;2-Methyl-1-cyclohexanol;2-Methylcyclohexanol;2-Methylcyclohexyl alcohol;NSC75845;2-Methylcyclohexan-1-ol;
PSA 20.23000
LogP 1.55740

Synthetic route

: 583-60-8
2-Methylcyclohexanone

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
With zinc hydride In tetrahydrofuran for 24h; Ambient temperature;	100%
With sodium isopropylate; acetonitrile In isopropyl alcohol at 80℃; for 1h; Catalytic behavior;	99%
gadolinium(III) isopropoxide In isopropyl alcohol at 30℃; for 1h;	98%

: 218623-12-2
2-(2-methyl-cyclohexyloxy)-tetrahydro-pyran

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
silica-supported prop-1-ylsulfonic acid In methanol	99.6%
With sulfuric acid; silica gel In methanol for 0.25h; Heating;	80%
With H14[NaP5W30O110] In methanol for 2h; Heating;	97 % Chromat.

: 95-48-7
ortho-cresol

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
With hydrogen In water at 20℃; under 7500.75 Torr; for 6h; Autoclave;	99.1%
With hydrogen at 100℃; under 3750.38 Torr; for 3h; Reagent/catalyst; Pressure; Temperature;	99%
With nickel(II) oxide; hydrogen; palladium In hexane at 80℃; under 7500.75 Torr; for 10h;	98%

: 583-60-8
2-Methylcyclohexanone

: 67-63-0
isopropyl alcohol

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
With [{2-(2-pyridyl)benzimidazole}RuCl2(PPh3)2]; potassium hydroxide at 82℃; for 4h;	97%
With potassium hydroxide for 4h; Ambient temperature;	8%
Mechanism; Product distribution; Irradiation;

: 1713-33-3
1,2-epoxy-1-methylcyclohexane

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
With sodium tetrahydroborate; triethylamine In water; acetonitrile Irradiation;	94%
With cobalt(II) tetrafluoroborate hexahydrate; hydrogen; zinc trifluoromethanesulfonate; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] In 1,4-dioxane at 60℃; under 30003 Torr; for 20h; Autoclave; regioselective reaction;	88 %Chromat.
With ammonia borane; C28H28Cl2CoNP2; erbium(III) triflate In tetrahydrofuran at 55℃; for 8h;	89 %Chromat.

: 5410-22-0
1,2-epoxy-3-methyl-cyclohexane

A: 583-59-5
2-Methylcyclohexanol

B: 591-23-1
m-methylcyclohexanol

Conditions

Conditions	Yield
With Li(1+)*C12H28AlO3(1-) In tetrahydrofuran; hexane at 0℃; for 0.17h; Yields of byproduct given. Title compound not separated from byproducts;	A 93% B n/a
With Li(1+)*C12H28AlO3(1-) In tetrahydrofuran; hexane at 0℃; for 0.17h;	A 93% B n/a

: 591-49-1
1-methylcyclohex-1-ene

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
Stage #1: 1-methylcyclohex-1-ene With 1-bromo-butane; sodium tetrahydroborate; Aliquat 336 at 20℃; for 16h; Addition; Hydroboration; Stage #2: With sodium hydroxide; dihydrogen peroxide at 40℃; for 1h; Oxidation;	78%
With sodium tetrahydroborate; (2,3,7,8,12,13,17,18-octaethylporphyrinato)rhodium(III) chloride; oxygen In tetrahydrofuran at 20 - 25℃; for 50h; Product distribution; Mechanism; other olefins, diene and acetylenes, other rhodium porphyrin, other conc. of catalyst;
With sodium tetrahydroborate; oxygen; (2,3,7,8,12,13,17,18-octaethylporphyrinato)rhodium(III) chloride In tetrahydrofuran Ambient temperature; 48-130 h; Yield given;

: 99522-16-4
2-Trimethylsilanylmethyl-cyclohexanol

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
With potassium tert-butylate; 18-crown-6 ether In water; dimethyl sulfoxide at 80℃; for 12h;	78%

: 106345-17-9
2-(6-Methyl-1-oxa-4-aza-spiro[4.5]dec-4-yl)-ethanol

A: 583-59-5
2-Methylcyclohexanol

B: 106345-21-5
2-(7-Methyl-4,5,6,7-tetrahydro-indol-1-yl)-ethanol

C: 111-42-2
2,2'-iminobis[ethanol]

Conditions

Conditions	Yield
With potassium hydroxide Heating; CH3ONa as reagent;	A n/a B 59% C n/a

...Expand

: 101934-18-3
1,5-bis(bromomagnesio)hexane

: 109-94-4
formic acid ethyl ester

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
In tetrahydrofuran	57%

: 75-16-1
methylmagnesium bromide

: 286-20-4
cyclohexane-1,2-epoxide

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
With Cu2(OTf)2; (-)-(aR)-[1,1'-binaphthalene]-8,8'-diyl dimethylphosphoramidite In tetrahydrofuran at -78 - 20℃; Ring cleavage; methylation;	45%

: 82166-21-0
methyl cyclohexane

A: 583-59-5
2-Methylcyclohexanol

B: 590-67-0
1-Methylcyclohexanol

Conditions

Conditions	Yield
With [(hydrotris(3,5-diphenyl-pyrazol-1-yl)borate)FeII(benzilate)]; oxygen; scandium tris(trifluoromethanesulfonate) In benzene at 20℃; Inert atmosphere;	A 13% B 45%
With [(hydrotris(3,5-diphenyl-pyrazol-1-yl)borate)FeII(benzilate)]; oxygen; pyridinium perchlorate In acetonitrile; benzene at 20℃; for 0.25h; Catalytic behavior; Reagent/catalyst;	A 15% B 44%
With 2,6-dimethylpyridine; Cumene hydroperoxide; [FeII(1,1’-(((pyridin-2-ylmethyl)azanediyl)bis(ethane-2,1-diyl))bis(3-(tert-butyl)urea))(H2O)(trifluoromethanesulfonate)](trifluoromethanesulfonate) In acetonitrile at -20.16 - 9.84℃; for 1h; Catalytic behavior; Inert atmosphere;

: 82166-21-0
methyl cyclohexane

A: 589-91-3
p-methylcyclohexanol

B: 583-59-5
2-Methylcyclohexanol

C: 590-67-0
1-Methylcyclohexanol

D: 591-23-1
m-methylcyclohexanol

Conditions

Conditions	Yield
With iodosylbenzene; 5,10,15,20-tetraphenyl-21 H,23-H-porphine manganese(III)chloride In benzene for 2h; Ambient temperature; pAr = 1 atm; Further byproducts given. Title compound not separated from byproducts;	A 18% B 20% C 24% D 3%
With iodosylbenzene; 5,10,15,20-tetraphenyl-21 H,23-H-porphine manganese(III)chloride In benzene for 2h; Ambient temperature; pAr= 1 atm; Further byproducts given. Title compound not separated from byproducts;	A 18% B 20% C 24% D 3%
With peracetic acid; tris(μ-oxo)di[(1,4,7-trimethyl-1,4,7-triazanonane)manganese(IV)] hexafluorophosphate In acetonitrile at 30℃; for 1h; Yield given. Further byproducts given. Yields of byproduct given;

...Expand

: C26H28O

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
With tetrahydrofuran; titanium(III) chloride; lithium for 40h; Heating;	20%

: 583-60-8
2-Methylcyclohexanone

A: 583-59-5
2-Methylcyclohexanol

B: 95-48-7
ortho-cresol

Conditions

Conditions	Yield
at 24.9℃; Equilibrium constant; other temperatures; calculated values;	A 17% B 8.6%
at 240 - 320℃; an metallbeschichtetem opt.-akt. Quarz;

: 917-64-6
methyl magnesium iodide

: 6628-80-4
trans-2-chlorocyclohexanol

A: 583-59-5
2-Methylcyclohexanol

B: 52829-98-8
1-cyclopentylethan-1-ol

Conditions

Conditions	Yield
With diethyl ether dl-trans-1-methyl-cyclohexanol-(2);

...Expand

: 1121-18-2
2-methyl-2-cyclohexen-1-one

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
With ethanol; sodium
With diisobutylaluminium hydride In hexane; dichloromethane at -78℃; Inert atmosphere;

: 79-97-0
2,2-bis(4-hydroxy-3-methylphenyl)propane

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
With manganese containing nickel catalyst at 170℃; Hydrogenation.unter Druck; d-cis-1-methyl-cyclohexanol-(2);
With manganese containing nickel catalyst at 170℃; Hydrogenation.unter Druck; l-cis-1-methyl-cyclohexanol-(2);

: 79-97-0
2,2-bis(4-hydroxy-3-methylphenyl)propane

A: 583-59-5
2-Methylcyclohexanol

B: 1490-05-7
4-isopropyl-2-methylcyclohexanol

Conditions

Conditions	Yield
in Gegenwart eines Kupfer, Kobalt und Mangan enthaltenen Nickelkatalysators.Hydrogenation;

: 60-29-7
diethyl ether

: 917-54-4
methyllithium

: 286-20-4
cyclohexane-1,2-epoxide

: 583-59-5
2-Methylcyclohexanol

...Expand

: 583-60-8
2-Methylcyclohexanone

A: 583-59-5
2-Methylcyclohexanol

B: 1194-91-8
3-methyl-2-oxo-cyclohexanecarbaldehyde

Conditions

Conditions	Yield
With diethyl ether; sodium; formic acid ethyl ester dl-trans-1-methyl-cyclohexanol-(2);

: 119-36-8
methyl salicylate

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
With CuO/Cr2O3 at 250℃; Hydrogenation;

: 1713-33-3
1,2-epoxy-1-methylcyclohexane

A: 583-59-5
2-Methylcyclohexanol

B: 590-67-0
1-Methylcyclohexanol

Conditions

Conditions	Yield
With sodium tert-pentoxide; sodium hydride; nickel dichloride In 1,2-dimethoxyethane at 65℃; for 40h; Yield given. Yields of byproduct given;

: 1713-33-3
1,2-epoxy-1-methylcyclohexane

A: 583-59-5
2-Methylcyclohexanol

B: 590-67-0
1-Methylcyclohexanol

: 93955-62-5
(1S,2S)-2-Isopropoxy-2-methyl-cyclohexanol

: 93955-63-6
(1R,2R)-2-Isopropoxy-1-methyl-cyclohexanol

Conditions

Conditions	Yield
In isopropyl alcohol Irradiation; Yield given. Yields of byproduct given;

...Expand

: 591-49-1
1-methylcyclohex-1-ene

A: 583-59-5
2-Methylcyclohexanol

B: 590-67-0
1-Methylcyclohexanol

Conditions

Conditions	Yield
With dihydrogen peroxide In acetonitrile Irradiation; Yield given. Yields of byproduct given;

: 1121-18-2
2-methyl-2-cyclohexen-1-one

A: 583-59-5
2-Methylcyclohexanol

B: 20461-30-7
2-methylcyclohex-2-en-1-ol

Conditions

Conditions	Yield
With sodium tetrahydroborate; alpha cyclodextrin In water Product distribution; influence of other cyclodextrin on the reduction;
With sodium tetrahydroborate; β‐cyclodextrin In water for 24h;	A 35 % Chromat. B 65 % Chromat.
With sodium tetrahydroborate In water Ambient temperature;	A 22 % Chromat. B 78 % Chromat.
With sodium tetrahydroborate; alpha cyclodextrin In water for 24h;	A 10 % Chromat. B 90 % Chromat.

: 1121-18-2
2-methyl-2-cyclohexen-1-one

A: 583-59-5
2-Methylcyclohexanol

B: 20461-30-7
2-methylcyclohex-2-en-1-ol

C: 583-60-8
2-Methylcyclohexanone

Conditions

Conditions	Yield
With lithium aluminium tetrahydride; cryptand 211 In tetrahydrofuran for 0.0833333h; Ambient temperature; Yield given. Yields of byproduct given;
With lithium aluminium tetrahydride In tetrahydrofuran for 0.0166667h; Ambient temperature; Yield given. Yields of byproduct given;

...Expand

: 444-30-4
2-(trifluoromethyl)phenol

: 583-59-5
2-Methylcyclohexanol

Conditions

Conditions	Yield
With hydrogen; nickel In methanol at 170℃; under 114000 Torr; for 24h; Yield given;

: 110-82-7
cyclohexane

: 82166-21-0
methyl cyclohexane

A: 589-91-3
p-methylcyclohexanol

B: 583-59-5
2-Methylcyclohexanol

C: 590-67-0
1-Methylcyclohexanol

D: 591-23-1
m-methylcyclohexanol

E: 583-60-8
2-Methylcyclohexanone

F: 591-24-2, 625-96-7
3-Methylcyclohexanone

Conditions

Conditions	Yield
5,10,15,20-tetraphenyl-21 H,23-H-porphine manganese(III)chloride for 2h; Product distribution; Mechanism; Ambient temperature; variations of reagents, pO2, protective atmosphere;

...Expand

: 82166-21-0
methyl cyclohexane

A: 583-59-5
2-Methylcyclohexanol

B: 590-67-0
1-Methylcyclohexanol

C: 589-92-4
1-methylcyclohexan-4-one

D: 591-24-2, 625-96-7
3-Methylcyclohexanone

Conditions

Conditions	Yield
With hydrogenchloride; oxygen; sodium L-ascorbate; 5,10,15,20-tetraphenyl-21 H,23-H-porphine manganese(III)chloride In benzene Ambient temperature; pH=8.5, pO2= 1 atm; Further byproducts given. Title compound not separated from byproducts;

...Expand

: 583-59-5
2-Methylcyclohexanol

: 583-60-8
2-Methylcyclohexanone

Conditions

Conditions	Yield
With dihydrogen peroxide; tetra(n-butyl)ammonium hydrogensulfate; sodium tungstate In tert-butyl alcohol at 90℃; for 0.5h;	100%
With jones reagent; silica gel In dichloromethane for 0.0833333h;	99%
With silica-supported Jones reagent In dichloromethane for 0.00269444h;	99.7%

: 110-87-2
3,4-dihydro-2H-pyran

: 583-59-5
2-Methylcyclohexanol

: 218623-12-2
2-(2-methyl-cyclohexyloxy)-tetrahydro-pyran

Conditions

Conditions	Yield
silica-supported prop-1-ylsulfonic acid In acetonitrile for 0.166667h;	99.8%
With sulfuric acid; silica gel for 0.0166667h; Irradiation; microwave;	80%
With H14[NaP5W30O110] In dichloromethane for 1h; Heating;	94 % Chromat.

: 583-59-5
2-Methylcyclohexanol

A: 95-48-7
ortho-cresol

B: 108-88-3
toluene

Conditions

Conditions	Yield
platinum; potassium oxide at 360℃;	A 98% B 2%
platinum; potassium oxide at 360℃; Product distribution; other content of catalyst;	A 98% B 2%

: 583-59-5
2-Methylcyclohexanol

: 98-59-9
p-toluenesulfonyl chloride

: 93570-98-0
Toluene-4-sulfonic acid 2-methyl-cyclohexyl ester

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In ethyl acetate at 0 - 20℃; for 96h;	95%

: 583-59-5
2-Methylcyclohexanol

: 108-24-7
acetic anhydride

: 5726-19-2
2-methylcyclohexyl acetate

Conditions

Conditions	Yield
With chloro-trimethyl-silane In acetonitrile for 2h;	91%

: 583-59-5
2-Methylcyclohexanol

: 22368-39-4
2,2,6-trichloro-6-methylcyclohexanone

Conditions

Conditions	Yield
With chlorine In N,N-dimethyl-formamide at 35 - 45℃; for 3h;	91%

: 583-59-5
2-Methylcyclohexanol

: 64-19-7
acetic acid

: 5726-19-2
2-methylcyclohexyl acetate

Conditions

Conditions	Yield
With toluene-4-sulfonic acid at 100 - 124℃; for 3h; Temperature;	89.8%
With sulfuric acid at 100 - 110℃;

: 583-59-5
2-Methylcyclohexanol

: 79-11-8
chloroacetic acid

: 519050-83-0
(2-methylcyclohexyl)oxyacetic acid

Conditions

Conditions	Yield
Stage #1: 2-Methylcyclohexanol With lithium In tetrahydrofuran for 16h; Inert atmosphere; Reflux; Stage #2: chloroacetic acid In tetrahydrofuran for 6h; Inert atmosphere; Reflux;	89%

: 583-59-5
2-Methylcyclohexanol

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: 109283-59-2
Trimethyl-(2-methyl-cyclohexyloxy)-silane

Conditions

Conditions	Yield
With potassium fluoride incorporated on clinoptilolite nanoparticles In dichloromethane at 20℃; for 1.25h; chemoselective reaction;	86%
With sulfonic acid functionalized silica In dichloromethane at 20℃; for 1h;	90 % Chromat.
With [Ti(IV)(salophen)(OTf)2] In dichloromethane at 20℃; for 0.25h;	98 %Chromat.

: 583-59-5
2-Methylcyclohexanol

: 956434-30-3
tert-Butyl 8-chloro-2,3-dihydropyrido[3,2-f][1,4]oxazepine-4(5H)-carboxylate

: 1154471-50-7
tert-butyl 8-[(2-methylcyclohexyl)oxy]-2,3-dihydropyrido[3,2-f][1,4]oxazepine-4(5H)-carboxylate

Conditions

Conditions	Yield
Stage #1: 2-Methylcyclohexanol With sodium hydride In toluene at 70℃; for 0.25h; Inert atmosphere; Stage #2: tert-Butyl 8-chloro-2,3-dihydropyrido[3,2-f][1,4]oxazepine-4(5H)-carboxylate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 100℃; for 2h; Inert atmosphere;	86%

: 583-59-5
2-Methylcyclohexanol

: 2094-72-6
1-Adamantanecarbonyl chloride

: Adamantane-1-carboxylic acid (1S,2S)-2-methyl-cyclohexyl ester

Conditions

Conditions	Yield
With pyridine In diethyl ether at 18 - 23℃;	80%

: 583-59-5
2-Methylcyclohexanol

: 1282619-49-1
ethyl 6-benzyl-2-(benzyloxy)-4-hydroxynicotinate

: 1282619-60-6
ethyl 6-benzyl-2-(benzyloxy)-4-(2-methylcyclohexyloxy)nicotinate

Conditions

Conditions	Yield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 20h;	80%

: 583-59-5
2-Methylcyclohexanol

: 484067-66-5
3,3,4-trichloro-3-butenoyl chloride

: 3,4,4-trichloro-but-3-enoic acid 2-methyl-cyclohexyl ester

Conditions

Conditions	Yield
With pyridine In diethyl ether at 20 - 23℃; for 22h;	77%

: 583-59-5
2-Methylcyclohexanol

: 1282619-52-6
ethyl 2-(benzyloxy)-4-hydroxy-6-phenethylnicotinate

: 1430415-02-3
ethyl 2-(benzyloxy)-4-(2-methylcyclohexyloxy)-6-phenethyl nicotinate

Conditions

Conditions	Yield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 20h;	76%
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; Mitsunobu Displacement;	51%

: 583-59-5
2-Methylcyclohexanol

: 822-87-7
2-Chlorocyclohexanone

: 66283-58-7
6-methyl-1,2,3,4-tetrahydrodibenzo[b,d]furan

Conditions

Conditions	Yield
With titanium tetrachloride In 2,2,2-trifluoroethanol Inert atmosphere; Reflux;	76%

: 75-77-4
chloro-trimethyl-silane

: 583-59-5
2-Methylcyclohexanol

: 109283-59-2
Trimethyl-(2-methyl-cyclohexyloxy)-silane

Conditions

Conditions	Yield
With urea at 20℃; for 4h;	73.4%

: 583-59-5
2-Methylcyclohexanol

: 84443-52-7
2,2,2-trichloroethyl heptanoate

: 5726-24-9
Heptanoic acid (R)-2-methyl-cyclohexyl ester

Conditions

Conditions	Yield
With porcine pancreatic lipase In n-heptane at 60℃; for 96h;	72%

: 583-59-5
2-Methylcyclohexanol

: 1445-79-0
trimethyl gallium

: dimethylgallium 2-methylcyclohexanoxide

Conditions

Conditions	Yield
In hexane at -40 - 20℃; for 3h; Inert atmosphere; Schlenk technique;	72%

: 64-18-6
formic acid

: 583-59-5
2-Methylcyclohexanol

: 1123-25-7
1-methyl-1-cyclohexanecarboxylic acid

Conditions

Conditions	Yield
With sulfuric acid at 20℃; Inert atmosphere;	70%
With sulfuric acid

: 583-59-5
2-Methylcyclohexanol

: 870-50-8
di-tert-butyl-diazodicarboxylate

: di-tert-butyl 1-(7-oxoheptan-2-yl)hydrazine-1,2-dicarboxylate

Conditions

Conditions	Yield
With cerium(III) chloride heptahydrate; tetrabutyl-ammonium chloride In acetonitrile for 19h; Inert atmosphere; Irradiation;	68%

: 79-20-9
acetic acid methyl ester

: 583-59-5
2-Methylcyclohexanol

: 5726-19-2
2-methylcyclohexyl acetate

Conditions

Conditions	Yield
With 1,3-dicyclohexylimidazol-2-ylidene at 25℃; for 0.25h;	67%

: 583-59-5
2-Methylcyclohexanol

: 1633-56-3
(13C)-formic acid

: 1-methylcyclohexanecarboxylic acid

Conditions

Conditions	Yield
With sulfuric acid at 25 - 30℃;	66%

2-Methylcyclohexanol Specification

The 2-Methylcyclohexanol with CAS registry number of 583-59-5 is also known as Cyclohexanol, 2-methyl-. The IUPAC name is 2-Methylcyclohexan-1-ol. It belongs to product categories of Industrial/Fine Chemicals. Its EINECS registry number is 209-512-0. In addition, the formula is C₇H₁₄O and the molecular weight is 114.21. This chemical is a colourless viscous liquid with an aromatic odour that may cause damage to health. It is slightly soluble in water and should be sealed in cool, dry place. What's more, this chemical can be used as organic chemical, solvent, lubricant additive, auxiliary and antioxidant. As it is harmful by inhalation, avoid contact with skin and eyes when using it.

Physical properties about 2-Methylcyclohexanol are: (1)ACD/LogP: 1.83; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.83; (4)ACD/LogD (pH 7.4): 1.83; (5)ACD/BCF (pH 5.5): 14.55; (6)ACD/BCF (pH 7.4): 14.55; (7)ACD/KOC (pH 5.5): 236.62; (8)ACD/KOC (pH 7.4): 236.62; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Index of Refraction: 1.462; (13)Molar Refractivity: 33.96 cm³; (14)Molar Volume: 123.4 cm³; (15)Surface Tension: 28.9 dyne/cm; (16)Density: 0.925 g/cm³; (17)Flash Point: 58.9 °C; (18)Enthalpy of Vaporization: 47.36 kJ/mol; (19)Boiling Point: 170.3 °C at 760 mmHg; (20)Vapour Pressure: 0.475 mmHg at 25 °C.

Preparation of 2-Methylcyclohexanol: it is prepared by reaction of 1,2-epoxy-1-methyl-cyclohexane. The reaction needs reagents Et₃N, NaBH₄and solvents acetonitrile, H₂O with other condition of irradiation. The yield is about 94 %.

2-Methylcyclohexanol is prepared by reaction of 1,2-epoxy-1-methyl-cyclohexane.

Uses of 2-Methylcyclohexanol: it is used to produce acetic acid-(2-methyl-cyclohexyl ester) by reaction with acetic acid anhydride. The reaction occurs with reagent chlorotrimethylsilane and solvent acetonitrile for 2 hours. The yield is about 91 %.

2-Methylcyclohexanol is used to produce acetic acid-(2-methyl-cyclohexyl ester) by reaction with acetic acid anhydride.

You can still convert the following datas into molecular structure:
1. Canonical SMILES: CC1CCCCC1O
2. InChI: InChI=1S/C7H14O/c1-6-4-2-3-5-7(6)8/h6-8H,2-5H2,1H3
3. InChIKey: NDVWOBYBJYUSMF-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intramuscular	1gm/kg (1000mg/kg)		Journal of Scientific and Industrial Research, Section C: Biological Sciences. Vol. 21, Pg. 342, 1962.

Product Name

2-Methylcyclohexanol

Synthetic route

2-Methylcyclohexanol Specification

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