Ethyl chloracetate supplier

Name
Ethyl chloroacetate
EINECS 203-294-0
CAS No. 105-39-5
Article Data114
CAS DataBase
Density 1.119 g/cm³
Solubility 20 g/L (20 ºC)
Melting Point -27 ºC
Formula C₄H₇ClO₂
Boiling Point 147.6 ºC at 760 mmHg
Molecular Weight 122.551
Flash Point 65.6 ºC
Transport Information UN 1181 6.1/PG 2
Appearance colourless liquid
Safety 45-61-7/9-16
Risk Codes 23/24/25-50-10
Molecular Structure
Hazard Symbols T; N
Synonyms Aceticacid, chloro-, ethyl ester (6CI,8CI,9CI);(Ethoxycarbonyl)methyl chloride;2-Chloroacetic acid ethyl ester;Chloroacetic acid ethyl ester;Ethyl 2-chloroacetate;Ethyl 2-monochloroacetate;Ethyl monochloracetate;Ethyl a-chloroacetate;NSC 8833;
PSA 26.30000
LogP 0.78830

Synthetic route

: 64-17-5
ethanol

: 79-11-8
chloroacetic acid

: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
With Candida antarctica lipase B at 20℃; for 36h; Enzymatic reaction;	97%
at 105℃; for 3h; Temperature; Molecular sieve;	97.4%
F-4SK (H form) In tetrachloromethane at 80℃; for 5h;	95%

: 79-11-8
chloroacetic acid

: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
With thionyl chloride In ethanol; dichloromethane for 0.583333h; Cooling with ice;	83%

: 623-33-6
glycine ethyl ester hydrochloride

: 79-04-9
chloroacetyl chloride

: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water; toluene at 20℃; for 13h; Cooling with ice;	80%

: 623-73-4
diazoacetic acid ethyl ester

: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
With tertiary butyl chloride; [HB(3,5-(CF3)2Pz)3]Ag(THF)	73%
With hydrogenchloride
With hydrogenchloride; diethyl ether

: 623-81-4
diethyl sulphite

: 79-11-8
chloroacetic acid

: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
sulfuric acid In ethanol Heating;	66%

: 141-97-9
ethyl acetoacetate

: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
With potassium bromate; hydrogenchloride In N,N-dimethyl-formamide at 20℃; for 12h;	63%

: 623-73-4
diazoacetic acid ethyl ester

A: 105-39-5
chloroacetic acid ethyl ester

B: 1520-50-9
but-2-enedioic acid diethyl ester

Conditions

Conditions	Yield
With tertiary butyl chloride; bis(μ2-2,2,2',2'-tetramethyl-1,3-benzene-di(propanoato-O,O'))rhodium-bismuth at 39.84℃; for 2h; Inert atmosphere;	A 46% B n/a

: 623-73-4
diazoacetic acid ethyl ester

: 140-29-4
phenylacetonitrile

A: 74185-57-2
2-benzyl-5-ethoxy-1,3-oxazole

B: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
aluminium trichloride In neat (no solvent) at 25℃;	A 31% B n/a

...Expand

: 7064-36-0
4-chloro-5-methyl-isoxazole

: 64-17-5
ethanol

A: 141-78-6
ethyl acetate

B: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
With pyridine for 5h; Heating;	A n/a B 25%

...Expand

: 623-73-4
diazoacetic acid ethyl ester

: 507-20-0
tertiary butyl chloride

A: 98551-46-3
2-chloro-3,3-dimethyl-butyric acid ethyl ester

B: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
Photolysis;
Irradiation.mit UV-Licht;

...Expand

: 623-73-4
diazoacetic acid ethyl ester

A: 26697-96-1
bis-(ethoxycarbonyl-chloro-chloromercurio-methyl)-mercury

B: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
With mercury dichloride at 0℃;

: 67-56-1
methanol

: 42345-82-4
(E)-1,2-dichloro-1-ethoxy-ethene

A: 96-34-4
methyl chloroacetate

B: 105-39-5
chloroacetic acid ethyl ester

...Expand

: 620-73-5
phenyl chloroacetate

: 64-17-5
ethanol

: 105-39-5
chloroacetic acid ethyl ester

: 620-73-5
phenyl chloroacetate

: 141-52-6
sodium ethanolate

: 105-39-5
chloroacetic acid ethyl ester

: 56-23-5
tetrachloromethane

: 128-09-6
N-chloro-succinimide

: 2678-54-8
ketene diethyl acetal

A: 74-85-1
ethene

B: 105-39-5
chloroacetic acid ethyl ester

...Expand

: 60-29-7
diethyl ether

: 191340-22-4
chloro-acetyl iodide

A: 75-03-6
ethyl iodide

B: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
at 25℃;
at 25℃; bei mehrtaegiger Einw. unter Lichtausschuss; reagiert analog mit Methylbutylaether;

...Expand

: 60-29-7
diethyl ether

: 191340-22-4
chloro-acetyl iodide

: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
at 25℃; unter Ausschluss von Licht;

: 64-17-5
ethanol

: 80944-05-4
1-ethoxy-2,2-dichloro-ethanol

: 151-50-8
potassium cyanide

: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
at 20℃;

...Expand

: 42345-82-4
(E)-1,2-dichloro-1-ethoxy-ethene

: 64-17-5
ethanol

: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
zweckmaessig in Gegenwart von Katalysatoren;

: 64-17-5
ethanol

: 17368-73-9
N-acetyl-2-chloroacetamide

A: 141-78-6
ethyl acetate

B: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
Product distribution; im Verhaeltnis 99:1;

...Expand

: 64-17-5
ethanol

: 15322-68-6
chloroacetyl-propionyl-amine

A: 105-37-3
Ethyl propionate

B: 105-39-5
chloroacetic acid ethyl ester

...Expand

: 64-17-5
ethanol

: 4960-82-1
dichlorodiacetamide

A: 105-39-5
chloroacetic acid ethyl ester

B: 79-07-2
Chloroacetamide

...Expand

: 64-17-5
ethanol

: 7218-27-1
N-(2-chloroethanoyl)benzamide

A: 93-89-0
benzoic acid ethyl ester

B: 105-39-5
chloroacetic acid ethyl ester

...Expand

: 64-17-5
ethanol

: 79628-75-4
3-(2-amino-4-methyl-anilino)-2-chloro-crotonic acid ethyl ester

A: 1792-41-2
2,5-dimethylbenzimidazole

B: 105-39-5
chloroacetic acid ethyl ester

...Expand

: 42345-82-4
(E)-1,2-dichloro-1-ethoxy-ethene

: 123-51-3
i-Amyl alcohol

A: 5326-92-1
3-methylbutyl chloroacetate

B: 105-39-5
chloroacetic acid ethyl ester

...Expand

: 42345-82-4
(E)-1,2-dichloro-1-ethoxy-ethene

: 111-70-6
n-heptan1ol

A: 34589-22-5
heptyl 2-chloroacetate

B: 105-39-5
chloroacetic acid ethyl ester

...Expand

: 80944-05-4
1-ethoxy-2,2-dichloro-ethanol

: 151-50-8
potassium cyanide

: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
With ethanol at 20℃;

: 42345-82-4
(E)-1,2-dichloro-1-ethoxy-ethene

: 110-15-6
succinic acid

A: 108-30-5
succinic acid anhydride

B: 105-39-5
chloroacetic acid ethyl ester

...Expand

: 42345-82-4
(E)-1,2-dichloro-1-ethoxy-ethene

: 89-78-1
menthol

A: 106916-72-7
2-isopropyl-5-methylcyclohexyl chloroethanoate

B: 105-39-5
chloroacetic acid ethyl ester

...Expand

: 42345-82-4
(E)-1,2-dichloro-1-ethoxy-ethene

: 105-39-5
chloroacetic acid ethyl ester

Conditions

Conditions	Yield
With alcohols
With mono-basic organic acids
With oxalic acid

: 95-77-2
3,4-dichlorophenol

: 105-39-5
chloroacetic acid ethyl ester

: 62855-72-5
ethyl 2-(3,4-dichlorophenoxy)acetate

Conditions

Conditions	Yield
With potassium carbonate In acetone at 80℃; for 18h;	100%
With ethanol; sodium ethanolate

: 105-39-5
chloroacetic acid ethyl ester

: 109-94-4
formic acid ethyl ester

: 33142-21-1
ethyl 2-chloro-3-oxopropanoate

Conditions

Conditions	Yield
With sodium ethanolate In tert-butyl methyl ether at 0 - 20℃; Inert atmosphere; Large scale;	100%
With sodium ethanolate In tert-butyl methyl ether at 0 - 20℃; Inert atmosphere; Large scale;	100%
With potassium tert-butylate In tetrahydrofuran at 0 - 20℃; for 16h; Inert atmosphere;	95%

: 105-39-5
chloroacetic acid ethyl ester

: 89124-45-8
acetic acid ethylester sulfonic acid

Conditions

Conditions	Yield
With sodium sulfate In ethanol; water	100%
With potassium sulfite; ethanol

: 1666-13-3
diphenyl diselenide

: 105-39-5
chloroacetic acid ethyl ester

: 51364-94-4
ethyl 2-(phenylselanyl)acetate

Conditions

Conditions	Yield
Stage #1: diphenyl diselenide With sodium tetrahydroborate In ethanol at 0℃; for 0.166667h; Inert atmosphere; Stage #2: chloroacetic acid ethyl ester In ethanol for 1h; Inert atmosphere;	100%
Stage #1: diphenyl diselenide With sodium tetrahydroborate; ethanol at 0 - 25℃; for 1h; Stage #2: chloroacetic acid ethyl ester at 25℃; for 2h;	98%
Stage #1: diphenyl diselenide With sodium tetrahydroborate In ethanol for 0.166667h; Stage #2: chloroacetic acid ethyl ester In ethanol at 50 - 55℃; for 0.75h;	94%

: 105-39-5
chloroacetic acid ethyl ester

: 85666-09-7
E-3-m-hydroxystyrylpyridine

: 79131-36-5
1-Ethoxycarbonylmethyl-4-[(E)-2-(3-hydroxy-phenyl)-vinyl]-pyridinium; chloride

Conditions

Conditions	Yield
In ethanol for 10h; Heating;	100%

: 105-39-5
chloroacetic acid ethyl ester

: 76799-30-9
1-<2,6-bis(benzyloxy)-4-hydroxyphenyl>-3-<3-(benzyloxy)-4-methoxyphenyl>propane

: 76820-12-7
1-<2,6-bis(benzyloxy)-4-(carbethoxymethoxy)phenyl>-3-(3-hydroxy-4-methoxyphenyl)propane

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 22h;	100%

: 105-39-5
chloroacetic acid ethyl ester

: 63240-52-8
2,3',6-tris(benzyloxy)-4-hydroxy-4'-methoxydihydrochalcone

: 76799-27-4
2,3',6-tris(benzyloxy)-4-(carbethoxymethoxy)-4'-methoxydihydrochalcone

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 40 - 65℃; for 19h;	100%

: 105-39-5
chloroacetic acid ethyl ester

: 588679-10-1
ethyl 2-(4-bromo-2-chlorophenoxy)acetate

Conditions

Conditions	Yield
Stage #1: 4-bromo-2-chlorophenol With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 1h; Stage #2: chloroacetic acid ethyl ester In N,N-dimethyl-formamide at 20℃;	100%

: 29799-07-3
4-adamantylphenol

: 105-39-5
chloroacetic acid ethyl ester

: 52804-25-8
(4-adamantyl-1-yl-phenoxy) acetic acid ethyl ester

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide	100%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;	94.6%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;	94.6%

: 372-20-3
3-fluorophenol

: 105-39-5
chloroacetic acid ethyl ester

: 777-70-8
(3-fluoro-phenoxy)-acetic acid ethyl ester

Conditions

Conditions	Yield
With potassium carbonate In acetone for 24h; Heating / reflux;	100%
With potassium carbonate In acetone for 8h; Reflux;	70%
With potassium carbonate In acetonitrile for 2h; Reflux;

: 105-39-5
chloroacetic acid ethyl ester

: 119-36-8
methyl salicylate

: 22511-42-8
methyl 2-(2-ethoxy-2-oxoethoxy)benzoate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 30 - 65℃; for 18h;	100%
With potassium carbonate In acetone for 11h; Reflux;	94%
With potassium iodide; potassium carbonate In acetonitrile
With potassium carbonate In N,N-dimethyl-formamide at 65 - 75℃;

: 394-32-1
1-(5-fluoro-2-hydroxyphenyl)ethan-1-one

: 105-39-5
chloroacetic acid ethyl ester

: 34849-57-5
(2-acetyl-4-fluorophenoxy)acetic acid ethyl ester

Conditions

Conditions	Yield
With potassium carbonate In acetone for 16h; Reflux; Inert atmosphere;	100%

: 3964-56-5
4-bromo-2-chlorophenol

: 105-39-5
chloroacetic acid ethyl ester

: 588679-10-1
ethyl 2-(4-bromo-2-chlorophenoxy)acetate

Conditions

Conditions	Yield
Stage #1: 4-bromo-2-chlorophenol; chloroacetic acid ethyl ester With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 1h; Inert atmosphere; Stage #2: chloroacetic acid ethyl ester In N,N-dimethyl-formamide at 20℃;	100%

: 21392-48-3
7-hydroxy-8-methyl-4-phenyl-chromen-2-one

: 105-39-5
chloroacetic acid ethyl ester

: 307547-31-5
ethyl (8-methyl-4-phenyl-2H-1-benzopyran-2-on-7-yloxy)-acetate

Conditions

Conditions	Yield
With potassium carbonate In acetone for 24h; Reflux;	100%
With potassium carbonate In acetone for 6h; Reflux;	96.94%

: 1245623-59-9
5-(5-chloro-2-thienyl)-4-(2-methoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

: 105-39-5
chloroacetic acid ethyl ester

: 1245623-60-2
ethyl [3-(5-chloro-2-thienyl)-4-(2-methoxyethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 80℃; for 6.5h;	100%
With potassium carbonate In acetonitrile at 80℃; for 6.5h;	100%
With potassium carbonate In acetonitrile at 80℃; for 6.5h;	100%

: 7480-35-5, 13286-59-4, 74165-73-4, 126456-43-7, 136030-00-7, 140632-19-5, 140632-20-8
(1S,2R)-1-amino-2-indanol

: 105-39-5
chloroacetic acid ethyl ester

: 862095-79-2
indeno[2,1-b]-1,4-oxazin-3(2H)-one,4,4a,9,9a-tetrahydro-,(4aR,9aS)-

Conditions

Conditions	Yield
Stage #1: (1S,2R)-1-amino-2-indanol With sodium hydride In tetrahydrofuran at 0 - 70℃; for 0.666667h; Stage #2: chloroacetic acid ethyl ester In tetrahydrofuran for 2.5h; Heating / reflux;	100%
With sodium hydride In tetrahydrofuran	85%

: 1539-42-0
bis[(2-pyridyl)methyl]amine

: 105-39-5
chloroacetic acid ethyl ester

: ethyl 2-(bis(pyridin-2-ylmethyl)amino)acetate

Conditions

Conditions	Yield
With sodium carbonate In acetonitrile for 18h; Reflux;	100%
Stage #1: bis[(2-pyridyl)methyl]amine With sodium hydrogencarbonate In acetonitrile for 0.166667h; Stage #2: chloroacetic acid ethyl ester In acetonitrile for 5h; Reflux; Inert atmosphere;
With triethylamine In ethanol for 12h; Reflux;

: 105-39-5
chloroacetic acid ethyl ester

: 38663-85-3
2-methoxyethyl isothiocyanate

: 589-16-2
4-aminoethylbenzene

: (Z)-2-((4-ethylphenyl)imino)-3-(2-methoxyethyl)thiazolidin-4-one

Conditions

Conditions	Yield
Stage #1: 2-methoxyethyl isothiocyanate; 4-aminoethylbenzene In ethanol at 78℃; for 12h; Knoevenagel Condensation; Stage #2: chloroacetic acid ethyl ester With sodium acetate In ethanol at 78℃; for 5h; regioselective reaction;	100%

...Expand

: 621-36-3
m-methylphenylacetic acid

: 105-39-5
chloroacetic acid ethyl ester

: C13H16O4

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran for 16h; Reflux; Inert atmosphere;	100%

: 28668-95-3
3-mercapto-5H-1,2,4-triazino[5,6-b]indole

: 105-39-5
chloroacetic acid ethyl ester

: 189325-51-7
ethyl ester of (1,2,4-triazino[5,6-b]indolyl-3-thio)acetic acid

Conditions

Conditions	Yield
With sodium In methanol; N,N-dimethyl-formamide at 60 - 100℃; for 15h; Alkylation;	99.5%
Stage #1: 3-mercapto-5H-1,2,4-triazino[5,6-b]indole With potassium carbonate microwave irradiation; Stage #2: chloroacetic acid ethyl ester for 0.0416667h; microwave irradiation;	89%

: 106-41-2
4-bromo-phenol

: 105-39-5
chloroacetic acid ethyl ester

: 6964-29-0
ethyl 2-(4-bromophenoxy)acetate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 80℃;	99.3%
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 4h;	99%
With potassium carbonate In acetone Reflux;	87%

: 75-21-8
oxirane

: [4-(diethylamino)phenyl]dichlorophosphine

: 105-39-5
chloroacetic acid ethyl ester

: ethyl [4-(diethylamino)phenyl](2-chloroethoxy)phosphoryl acetate

Conditions

Conditions	Yield
at -5 - 20℃; for 2h; Inert atmosphere;	99.3%

...Expand

: 540-38-5
4-Iodophenol

: 105-39-5
chloroacetic acid ethyl ester

: 90794-33-5
4-iodophenoxyacetic acid ethyl ester

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; Inert atmosphere; Schlenk technique;	99%
With potassium carbonate In N,N-dimethyl-formamide for 16h;	98%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;	96%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;
With potassium carbonate In N,N-dimethyl-formamide at 20℃;

: 52542-59-3, 192520-17-5
bis(triphenylphosphineiminium) pentacarbonylmanganate(1-)

: 105-39-5
chloroacetic acid ethyl ester

A: 10170-69-1
dimanganese decacarbonyl

B: 14100-30-2
pentacarbonylchloromanganese(I)

C: η1-(CH2COOEt) manganese pentacarbonyl

Conditions

Conditions	Yield
In tetrahydrofuran (N2 or Ar); 25°C, rapid mixing; determination by NMR;	A 1% B 0% C 99%
In chloroform-d1 (N2 or Ar); 25°C, rapid mixing; determination by NMR;	A 1% B 0% C 99%

...Expand

: 66129-30-4
6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine-3(2H)-thione

: 105-39-5
chloroacetic acid ethyl ester

: 1033038-23-1
ethyl-2-(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)acetate

Conditions

Conditions	Yield
With sodium hydroxide In ethanol at 20℃; for 3h;	99%

: 946415-03-8
C19H20N2

: 105-39-5
chloroacetic acid ethyl ester

: 1255528-61-0
C23H27N2O2(1+)*I(1-)

Conditions

Conditions	Yield
With sodium iodide In acetone at 20℃; for 18h;	99%

: 16714-25-3
2-azidobenzaldehyde

: 105-39-5
chloroacetic acid ethyl ester

: C11H11N3O3

Conditions

Conditions	Yield
With sodium In ethanol at 20℃; for 4h;	99%

: 40064-34-4
piperidine-4,4-diol hydrochloride

: 105-39-5
chloroacetic acid ethyl ester

: ethyl 2-(4-oxopiperidin-1-yl)acetate

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 75℃;	99%

: 103027-41-4
1-(tert-butyldimethylsilyl)-4-(4',4',5',5'-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-5-ol

: 105-39-5
chloroacetic acid ethyl ester

: C14H13IO3

Conditions

Conditions	Yield
With potassium carbonate In acetone at 115℃; for 2h;	99%

: 5150-42-5
2,3-dimethoxyphenol

: 105-39-5
chloroacetic acid ethyl ester

: 861085-96-3
ethyl (2,3-dimethoxyphenoxy)acetate

Conditions

Conditions	Yield
Stage #1: 2,3-dimethoxyphenol With sodium hydride In tetrahydrofuran; dimethyl sulfoxide at 0℃; for 0.5h; Inert atmosphere; Stage #2: chloroacetic acid ethyl ester In tetrahydrofuran; dimethyl sulfoxide at 20℃; for 15h; Inert atmosphere;	98.8%

Ethyl chloracetate Consensus Reports

Reported in EPA TSCA Inventory.

Ethyl chloracetate Standards and Recommendations

DOT Classification: 6.1; Label: Poison

Ethyl chloracetate Specification

The CAS registry number of Ethyl chloracetate is 105-39-5. Its EINECS registry number is 203-294-0. The IUPAC name is ethyl 2-chloroacetate. In addition, the molecular formula is C₄H₇ClO₂. What's more, it is a kind of colourless liquid and can be used as a pharmaceutical intermediate. It is incompatible with acids, bases, oxidizing agents and reducing agents.

Physical properties about this chemical are: (1)ACD/LogP: 0.94; (2)ACD/LogD (pH 5.5): 0.94; (3)ACD/LogD (pH 7.4): 0.94; (4)ACD/BCF (pH 5.5): 3.05; (5)ACD/BCF (pH 7.4): 3.05; (6)ACD/KOC (pH 5.5): 77.3; (7)ACD/KOC (pH 7.4): 77.3; (8)#H bond acceptors: 2; (9)#Freely Rotating Bonds: 3; (10)Polar Surface Area: 26.3 Å²; (11)Index of Refraction: 1.411; (12)Molar Refractivity: 27.2 cm³; (13)Molar Volume: 109.4 cm³; (14)Polarizability: 10.78 ×10^-24cm³; (15)Surface Tension: 29.2 dyne/cm; (16)Density: 1.119 g/cm³; (17)Flash Point: 65.6 °C; (18)Enthalpy of Vaporization: 40.43 kJ/mol; (19)Boiling Point: 147.6 °C at 760 mmHg; (20)Vapour Pressure: 4.39 mmHg at 25°C.

Preparation of Ethyl chloracetate: it can be prepared by chloroacetic acid and ethanol. This reaction will need reagents P₂O₅, CuSO₄ and Na₂SO₄. The reaction time is 2 hours by heating. The yield is about 45%.

Ethyl chloracetate can be prepared by chloroacetic acid and ethanol

Uses of Ethyl chloracetate: it can react with 1-(N-phenylamino)-3-butoxypropane-2-thiol to get (1-butoxymethyl-2-phenylamino-ethylsulfanyl)-acetic acid ethyl ester. This reaction will need reagent NaOH and solvent H₂O. The reaction time is 1 hours at reaction temperature of 30-40 °C. The yield is about 32%.

Ethyl chloracetate can react with 1-(N-phenylamino)-3-butoxypropane-2-thiol to get (1-butoxymethyl-2-phenylamino-ethylsulfanyl)-acetic acid ethyl ester

When you are using this chemical, please be cautious about it as the following:
This chemical is flammable. And it is toxic by inhalation, in contact with skin and if swallowed. Moreover, it is very toxic to aquatic organisms. During using it, you should keep away from sources of ignition. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.). In addition, you should avoid release to the environment and you can refer to special instructions/safety data sheets. Besides, keep container tightly closed and in a well-ventilated place after using it.

You can still convert the following datas into molecular structure:
(1)SMILES: ClCC(=O)OCC
(2)InChI: InChI=1/C4H7ClO2/c1-2-7-4(6)3-5/h2-3H2,1H3
(3)InChIKey: VEUUMBGHMNQHGO-UHFFFAOYAS

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	350mg/kg (350mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 59, 1986.
mouse	LD50	subcutaneous	250mg/kg (250mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954.
rabbit	LD50	skin	230mg/kg (230mg/kg)		Toxicology and Applied Pharmacology. Vol. 42, Pg. 417, 1977.
rat	LC50	inhalation	3330uL/m³/4H (3.33mL/m³)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: DYSPNEA	BG Chemie: Toxicological Evaluations, Five Potential Health Hazards of Existing Chemicals. Vol. 5, Pg. 71, 1993.
rat	LD50	oral	180mg/kg (180mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA SKIN AND APPENDAGES (SKIN): HAIR: OTHER	BG Chemie: Toxicological Evaluations, Five Potential Health Hazards of Existing Chemicals. Vol. 5, Pg. 71, 1993.
rat	LD50	skin	161mg/kg (161mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" SKIN AND APPENDAGES (SKIN): HAIR: OTHER	BG Chemie: Toxicological Evaluations, Five Potential Health Hazards of Existing Chemicals. Vol. 5, Pg. 71, 1993.

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