Thiophosphoryl chloride supplier

Name
Thiophosphoryl chloride
EINECS 223-622-6
CAS No. 3982-91-0
Article Data134
CAS DataBase
Density 1.789 g/cm³
Solubility hydrolyzes in H2O, forming H3PO4, HCl, H2S; hydrolyzes rapidly in alkaline solutions; soluble benzene, CCl4, CS2, chloroform [MER06]
Melting Point -35 °C
Formula Cl₃PS
Boiling Point 125 °C at 760 mmHg
Molecular Weight 169.399
Flash Point
Transport Information UN 1837 8/PG 2
Appearance UN 1837 8/PG 2
Safety 26-28-36/37/39-45-61
Risk Codes 22-26-34-52/53
Molecular Structure
Hazard Symbols T+
Synonyms Thiophosphorylchloride (8CI);NSC 158334;Phosphorothionic trichloride;Phosphorus sulfidetrichloride;Phosphorus sulfochloride;Phosphorus thiochloride;Phosphorusthiotrichloride;Phosphorus trichloride sulfide;Thiophosphoric acidtrichloride;Thiophosphoric trichloride;Thiophosphoryl chloride (PSCl3);Thiophosphoryl trichloride;Trichlorophosphine sulfide;Trichlorophosphorusthioxide;phosphorothioic trichloride;Fosforthiochlorid;Phosphorus thiochloride;
PSA 41.90000
LogP 3.57790

Synthetic route

: 7704-34-9
sulfur

: 7719-12-2, 52843-90-0
phosphorus trichloride

: 3982-91-0
trichlorothiophosphine

Conditions

Conditions	Yield
With disulfur dichloride; iron(III) chloride In neat (no solvent) addn. of a mixt. of 140 g PCl3 and 1.7 g S2Cl2 drop by drop to a hot mixt. of 160 g PSCl3, 2 g anhydrous FeCl3 and 38 g S on stirring and refluxing (4.5 h); refluxing for 1 h, distg. off PSCl3;;	100%
In neat (no solvent) react. molten S with PCl3 at 124-126 °C at ambient pressure; use of a catalyst formed on melting S with active carbon and boiling in PSCl3 at 200 °C;;
disulfur dichloride In not given react. with S2Cl2 as catalyst;;

: barium sulfide

: 10026-13-8, 874483-75-7
phosphorus pentachloride

A: 3982-91-0
trichlorothiophosphine

B: phosphorous (V) sulfide

C: barium(II) chloride

Conditions

Conditions	Yield
In neat (no solvent) react. on heating under blazing up;;

...Expand

: calcium(II) sulfide

: 10026-13-8, 874483-75-7
phosphorus pentachloride

A: 3982-91-0
trichlorothiophosphine

B: phosphorous (V) sulfide

C: calcium chloride

Conditions

Conditions	Yield
In neat (no solvent) react. on heating under blazing up;;

...Expand

: 10026-13-8, 874483-75-7
phosphorus pentachloride

: mercury sulfide

A: 3982-91-0
trichlorothiophosphine

B: phosphorous (V) sulfide

C: mercury dichloride

Conditions

Conditions	Yield
In neat (no solvent) byproducts: thiosulfate; react. on heating;;

...Expand

: 7719-09-7
thionyl chloride

: phosphorus

A: 10025-67-9
disulfur dichloride

B: 3982-91-0
trichlorothiophosphine

C: 10026-13-8, 874483-75-7
phosphorus pentachloride

D: 7446-09-5
sulfur dioxide

E: 7719-12-2, 52843-90-0
phosphorus trichloride

Conditions

Conditions	Yield
In neat (no solvent) excess of SOCl2; 180°C;;
In neat (no solvent) excess of SOCl2; 180°C;;

...Expand

: 7446-09-5
sulfur dioxide

: 7719-12-2, 52843-90-0
phosphorus trichloride

A: 3982-91-0
trichlorothiophosphine

B: 7704-34-9
sulfur

Conditions

Conditions	Yield
In neat (no solvent) byproducts: POCl3; decompn. of SO2- and PCl3-vapours in a calcinating tube;; formation of POCl3, PSCl3 and a small amount of S;;
In neat (no solvent) byproducts: POCl3; decompn. of SO2- and PCl3-vapours in a calcinating tube;; formation of POCl3, PSCl3 and a small amount of S;;

...Expand

: 7446-09-5
sulfur dioxide

: 7719-12-2, 52843-90-0
phosphorus trichloride

A: 3982-91-0
trichlorothiophosphine

B: 10025-87-3, 12599-09-6, 63736-95-8
trichlorophosphate

Conditions

Conditions	Yield
tetramethyl ammonium-pyrosulfite 50°C;
phosphorus tribromide 50°C;
phosphorus(V) oxybromide 50°C;

...Expand

: 10025-67-9
disulfur dichloride

: tricalcium diphosphate

A: 3982-91-0
trichlorothiophosphine

B: 10025-87-3, 12599-09-6, 63736-95-8
trichlorophosphate

C: 7719-12-2, 52843-90-0
phosphorus trichloride

Conditions

Conditions	Yield
With silica gel In neat (no solvent) byproducts: SiCl4; react. of Ca3(PO4)2 with S2Cl2 at 1000 °C in presence of SiO2;; after 1 h 9.5 % phosphate are caused to react.;;
In neat (no solvent) react. of Ca3(PO4)2 with S2Cl2 at 1000 °C;; after 1 h 19.5 % phosphate are caused to react.;;
In neat (no solvent) react. of Ca3(PO4)2 with S2Cl2 at 1000 °C;; after 1 h 19.5 % phosphate are caused to react.;;
With SiO2 In neat (no solvent) byproducts: SiCl4; react. of Ca3(PO4)2 with S2Cl2 at 1000 °C in presence of SiO2;; after 1 h 9.5 % phosphate are caused to react.;;

...Expand

: 10025-67-9
disulfur dichloride

: phosphorus

A: 3982-91-0
trichlorothiophosphine

B: 7704-34-9
sulfur

C: 7719-12-2, 52843-90-0
phosphorus trichloride

Conditions

Conditions	Yield
In neat (no solvent) addn. of P (excess) to boiling S2Cl2;;

...Expand

: 10025-67-9
disulfur dichloride

: phosphorus

A: 3982-91-0
trichlorothiophosphine

B: 7704-34-9
sulfur

Conditions

Conditions	Yield
In neat (no solvent) addn. of P to boiling S2Cl2;;
In neat (no solvent) react. at boiling temp.;;
With Fe or Al In neat (no solvent) heating P with S2Cl2 in presence of Fe or Al;;
In neat (no solvent) heating P with S2Cl2;;

...Expand

: 7719-09-7
thionyl chloride

: 7719-12-2, 52843-90-0
phosphorus trichloride

A: 3982-91-0
trichlorothiophosphine

B: 10026-13-8, 874483-75-7
phosphorus pentachloride

C: 10025-87-3, 12599-09-6, 63736-95-8
trichlorophosphate

Conditions

Conditions	Yield
In neat (no solvent) slowly at 80-160°C;; POCl3 only supposed;;

...Expand

: 7719-09-7
thionyl chloride

: 7803-51-2
phosphan

A: 7647-01-0
hydrogenchloride

B: 3982-91-0
trichlorothiophosphine

C: phosphorus

D: 1314-85-8
phosphorus sulfide

E: 10025-87-3, 12599-09-6, 63736-95-8
trichlorophosphate

Conditions

Conditions	Yield
In neat (no solvent) room temp.;; further unidentified liquid products;;

...Expand

: 7719-09-7
thionyl chloride

: phosphorous (V) sulfide

A: 10025-67-9
disulfur dichloride

B: 3982-91-0
trichlorothiophosphine

C: 7446-09-5
sulfur dioxide

D: phosphorus pentoxide

E: 7704-34-9
sulfur

Conditions

Conditions	Yield
In neat (no solvent) 100-150°C;;	A 0% B n/a C n/a D 0% E n/a
In neat (no solvent) 100-150°C;;	A 0% B n/a C n/a D 0% E n/a

...Expand

: 7719-09-7
thionyl chloride

: phosphorous (V) sulfide

A: 10025-67-9
disulfur dichloride

B: 3982-91-0
trichlorothiophosphine

C: 7446-09-5
sulfur dioxide

D: 7704-34-9
sulfur

Conditions

Conditions	Yield
In neat (no solvent) 100-150°C;;	A 0% B n/a C n/a D n/a

...Expand

: 7719-09-7
thionyl chloride

: phosphorous

A: 10025-67-9
disulfur dichloride

B: 3982-91-0
trichlorothiophosphine

C: 10026-13-8, 874483-75-7
phosphorus pentachloride

D: 7446-09-5
sulfur dioxide

E: 7719-12-2, 52843-90-0
phosphorus trichloride

Conditions

Conditions	Yield
In neat (no solvent) excess of SOCl2; 180°C;;
In neat (no solvent) excess of SOCl2; 180°C;;

...Expand

: 7719-12-2, 52843-90-0
phosphorus trichloride

: 3982-91-0
trichlorothiophosphine

Conditions

Conditions	Yield
With sulfur at 76°C, in common pressure;	0%
With sulfur; barium sulfide in autoclave at 150°C for 4-5 h;	>99
With sulfur; calcium(II) sulfide in autoclave at 150°C for 4-5 h;	>99

: 10025-67-9
disulfur dichloride

: 7719-12-2, 52843-90-0
phosphorus trichloride

A: 3982-91-0
trichlorothiophosphine

B: 10026-13-8, 874483-75-7
phosphorus pentachloride

Conditions

Conditions	Yield
In neat (no solvent) 6h, 160°C;;	A >99 B >99
In neat (no solvent) 6h, 160°C;;	A >99 B >99

...Expand

: 7791-25-5
sulfuryl dichloride

: 7719-12-2, 52843-90-0
phosphorus trichloride

A: 3982-91-0
trichlorothiophosphine

B: 10025-87-3, 12599-09-6, 63736-95-8
trichlorophosphate

Conditions

Conditions	Yield
In neat (no solvent) simultaneous formation of POCl3 and PSCl3 via reaction of PCl3 with SO2Cl2;; isolation via fractionation;;
In not given react. with SO2Cl2;; fractional distn.;;
In not given react. with SO2Cl2;; fractional distn.;;

...Expand

: 10025-67-9
disulfur dichloride

: calcium metaphosphate

A: 3982-91-0
trichlorothiophosphine

B: 10025-87-3, 12599-09-6, 63736-95-8
trichlorophosphate

C: 7719-12-2, 52843-90-0
phosphorus trichloride

Conditions

Conditions	Yield
With silica gel In neat (no solvent) byproducts: SiCl4; react. of Ca(PO3)2 with S2Cl2 at 1000 °C in presence of SiO2;;
With SiO2 In neat (no solvent) byproducts: SiCl4; react. of Ca(PO3)2 with S2Cl2 at 1000 °C in presence of SiO2;;

...Expand

: 10025-67-9
disulfur dichloride

: 12440-00-5
phosphorus(III) oxide

A: 3982-91-0
trichlorothiophosphine

B: 7446-09-5
sulfur dioxide

C: 10025-87-3, 12599-09-6, 63736-95-8
trichlorophosphate

Conditions

Conditions	Yield
In neat (no solvent) byproducts: S; vigorous reaction;;

...Expand

: 10025-67-9
disulfur dichloride

: phosphorous

A: 3982-91-0
trichlorothiophosphine

B: 7704-34-9
sulfur

C: 7719-12-2, 52843-90-0
phosphorus trichloride

Conditions

Conditions	Yield
In neat (no solvent) in coldness under inflammation;;

...Expand

: 10026-13-8, 874483-75-7
phosphorus pentachloride

: 333-20-0
potassium thioacyanate

A: 10025-67-9
disulfur dichloride

B: 3982-91-0
trichlorothiophosphine

C: potassium chloride

D: 506-77-4
cyanogen chloride

Conditions

Conditions	Yield
In neat (no solvent) haeting at lower temp.; formation of CNCl, PSCl3, KCl and a small amount of S2Cl2;;

...Expand

: 10026-13-8, 874483-75-7
phosphorus pentachloride

: 333-20-0
potassium thioacyanate

A: 3982-91-0
trichlorothiophosphine

B: potassium chloride

C: 506-77-4
cyanogen chloride

Conditions

Conditions	Yield
heating;
heating;

...Expand

: lead(II) thiosulfate

: 10026-13-8, 874483-75-7
phosphorus pentachloride

A: 3982-91-0
trichlorothiophosphine

B: 7719-09-7
thionyl chloride

C: lead(II) chloride

D: 10025-87-3, 12599-09-6, 63736-95-8
trichlorophosphate

Conditions

Conditions	Yield
In neat (no solvent) heating PbS2O3 (dryed at 400 °C) with a reflux condenser; react. starting without heating, react. accelerated on heating; formation of POCl3, SOCl2, PSCl3 and PbCl2 as residue;;

...Expand

: phosphorous (V) sulfide

: 10025-87-3, 12599-09-6, 63736-95-8
trichlorophosphate

A: 3982-91-0
trichlorothiophosphine

B: 86119-84-8, 7664-38-2
phosphoric acid

Conditions

Conditions	Yield
In neat (no solvent) react. with P2S5 in a sealing tube at 150 °C;;
In neat (no solvent) heating in a sealing tube at 150 °C;;
In neat (no solvent) react. with P2S5 in a sealing tube at 150 °C;;

...Expand

: 10026-13-8, 874483-75-7
phosphorus pentachloride

: 3982-91-0
trichlorothiophosphine

Conditions

Conditions	Yield
With metal sulfide In not given byproducts: metal chloride; react. with metal sulfides forming PSCl3 and corresponding metal chlorides;;
With hydrogen sulfide In neat (no solvent) byproducts: HCl; react. of dry H2S with PCl5 under heating;;
With hydrogen sulfide In neat (no solvent) byproducts: HCl;
With metal chloride In not given byproducts: metal sulfide; react. of PCl5 with metal chloride;;
With metal chloride In not given byproducts: metal sulfide; react. of PCl5 with metal chloride;;

: 3931-89-3
thiophosphoryl(V) bromide

: 10026-13-8, 874483-75-7
phosphorus pentachloride

A: 3982-91-0
trichlorothiophosphine

B: 29679-77-4
phosphorus pentabromide

Conditions

Conditions	Yield
In not given react. with PSBr3;;
In not given react. with PSBr3;;

...Expand

: 10026-13-8, 874483-75-7
phosphorus pentachloride

: 7783-06-4
hydrogen sulfide

: 3982-91-0
trichlorothiophosphine

Conditions

Conditions	Yield
In neat (no solvent) react. with liquid H2S;;
In carbon disulfide passing H2S through a liquid mixt. of PCl5 and CS2;; distn. in a stream of CO2;;
In not given react. of liquid H2S with PCl5;;

: potassium sulfide

: 10026-13-8, 874483-75-7
phosphorus pentachloride

A: 3982-91-0
trichlorothiophosphine

B: potassium chloride

C: phosphorous (V) sulfide

Conditions

Conditions	Yield
In neat (no solvent) react. on heating under blazing up;;

...Expand

: tin disulfide

: 10026-13-8, 874483-75-7
phosphorus pentachloride

A: 3982-91-0
trichlorothiophosphine

B: phosphorous (V) sulfide

C: tin(ll) chloride

Conditions

Conditions	Yield
In neat (no solvent) byproducts: thiosulfate; react. on haeting;;

...Expand

: 3982-91-0
trichlorothiophosphine

: 7732-18-5
water

A: 52826-97-8
PSCl2(1+)

B: 14700-96-0, 14835-24-6, 15723-23-6, 16547-50-5, 16885-04-4, 16887-00-6, 16904-11-3, 16904-12-4, 16999-02-3, 20337-89-7, 20499-73-4, 22537-15-1, 22537-27-5, 22541-73-7, 22541-74-8, 24203-47-2, 33944-49-9, 34937-26-3, 37352-90-2
clorine

Conditions

Conditions	Yield
In gas Kinetics; High Pressure; the reagent ions were generated in an electron impact high-pressure ion source contg. H2O; the reagent ions were selected using a quadrupole mass filter before being injected into a drift region contg. helium carriergas; at 298 K; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A 100% B n/a

...Expand

: 3982-91-0
trichlorothiophosphine

: 7732-18-5
water

: HPSCl3(1+)

Conditions

Conditions	Yield
In gas Kinetics; High Pressure; the reagent ions were generated in an electron impact high-pressure ion source contg. H2O; the reagent ions were selected using a quadrupole mass filter before being injected into a drift region contg. helium carriergas; at 298 K; monitoring by quadrupole mass spectrometer at the end of the flow tube;	100%

: 3982-91-0
trichlorothiophosphine

: TamBP phenol

: C42H72N3O21P7S

Conditions

Conditions	Yield
With caesium carbonate In acetonitrile at 0 - 20℃; for 12h;	98%

: 3982-91-0
trichlorothiophosphine

: sodium 3,5-bis(borane-diphenylphosphino)phenolate*2(tetrahydrofurane)

: 436805-36-6
chloro bis(3,5-bis(borane-diphenylphosphino)-phenoxy)thiophosphate

Conditions

Conditions	Yield
In tetrahydrofuran byproducts: NaCl; in the absence of air using Schlenk techniques; mixed between -95 and -100°C under stirring; mixt. stirred overnight at room temp.; partially concd. (vac.); ppt. centrifuged; filtered under Ar; filtrate evapd; as oil;	97.5%

: 3982-91-0
trichlorothiophosphine

: 10102-44-0
Nitrogen dioxide

A: OPSCl3(1+)

B: NO*PSCl3(1+)

C: 10102-43-9
nitrogen(II) oxide

D: oxygen

Conditions

Conditions	Yield
In gas Kinetics; High Pressure; the reagent ions were generated in an electron impact high-pressure ion source contg. NO2; the reagent ions were selected using a quadrupole mass filter before being injected into a drift region contg. helium carriergas; at 298 K; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A 97% B 3% C n/a D n/a

...Expand

: 3982-91-0
trichlorothiophosphine

: 201230-82-2
carbon monoxide

A: 14989-32-3
sulphur monochloride

B: 52826-97-8
PSCl2(1+)

C: PSCl3(1+)

D: 75601-84-2
PCl2(1+)

E: 14700-96-0, 14835-24-6, 15723-23-6, 16547-50-5, 16885-04-4, 16887-00-6, 16904-11-3, 16904-12-4, 16999-02-3, 20337-89-7, 20499-73-4, 22537-15-1, 22537-27-5, 22541-73-7, 22541-74-8, 24203-47-2, 33944-49-9, 34937-26-3, 37352-90-2
clorine

Conditions

Conditions	Yield
In gas Kinetics; High Pressure; the reagent ions were generated in an electron impact high-pressure ion source contg. CO; the reagent ions were selected using a quadrupole massfilter before being injected into a drift region contg. helium carrier gas; at 298 K; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A n/a B 93% C 1% D 6% E n/a

...Expand

: 3982-91-0
trichlorothiophosphine

: 10024-97-2
dinitrogen monoxide

A: 14989-32-3
sulphur monochloride

B: 52826-97-8
PSCl2(1+)

C: PSCl3(1+)

D: 75601-84-2
PCl2(1+)

E: 14700-96-0, 14835-24-6, 15723-23-6, 16547-50-5, 16885-04-4, 16887-00-6, 16904-11-3, 16904-12-4, 16999-02-3, 20337-89-7, 20499-73-4, 22537-15-1, 22537-27-5, 22541-73-7, 22541-74-8, 24203-47-2, 33944-49-9, 34937-26-3, 37352-90-2
clorine

Conditions

Conditions	Yield
In gas Kinetics; High Pressure; the reagent ions were generated in an electron impact high-pressure ion source contg. N2O; the reagent ions were selected using a quadrupole mass filter before being injected into a drift region contg. helium carriergas; at 298 K; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A n/a B 93% C 1% D 6% E n/a
In gas Kinetics; byproducts: O; High Pressure; the reagent ions were generated in an electron impact high-pressure ion source contg. N2O; the reagent ions were selected using a quadrupole mass filter before being injected into a drift region contg. helium carriergas; at 298 K; O was also obtained; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A n/a B 69% C 18% D 13% E n/a

...Expand

: 3982-91-0
trichlorothiophosphine

: 7664-41-7
ammonia

: 55145-67-0, 13455-05-5
phosphorothioic triamide

Conditions

Conditions	Yield
In chloroform dissolving NH3-gas at -10°C in dry CHCl3; dropwisre addn. of PSCl3 in CHCl3 during 1.5 h; passing NH3 through the soln. at -10°C; sucking off; drying in vac. and dissolving in CHCl3; boiling for 3-4 h in presence of diethylamine;; recrystn. from hot methanol;;	90%
In chloroform dissolving NH3-gas at -10°C in dry CHCl3; dropwisre addn. of PSCl3 in CHCl3 during 1.5 h; passing NH3 through the soln. at -10°C; sucking off; drying in vac. and dissolving in CHCl3; boiling for 3-4 h in presence of diethylamine;; recrystn. from hot methanol;;	90%
In not given formation from PSCl3 and NH3;;

: 3982-91-0
trichlorothiophosphine

: 28240-68-8
methylenebis(dichlorophosphine)

: 1499-32-7
methylene-bis-(phosphonic dichloride)

Conditions

Conditions	Yield
With aluminum (III) chloride at 110 - 140℃; for 6h; Inert atmosphere;	89%

: 3982-91-0
trichlorothiophosphine

: 67-63-0
isopropyl alcohol

: 19021-61-5
O-isopropyl phosphorodichloridothioate

Conditions

Conditions	Yield
With pyridine at 20℃; for 2h;	84%

: 3982-91-0
trichlorothiophosphine

: 98-54-4
para-tert-butylphenol

: 68591-35-5
C10H13Cl2OPS

Conditions

Conditions	Yield
Stage #1: para-tert-butylphenol With sodium hydroxide In water at 0℃; Stage #2: trichlorothiophosphine With tetrabutylammomium bromide In dichloromethane; water at 0 - 20℃; for 5h;	81%

: 3982-91-0
trichlorothiophosphine

: 7727-37-9
nitrogen

A: 52826-97-8
PSCl2(1+)

B: PSCl(1+)

C: PSCl3(1+)

D: 75601-84-2
PCl2(1+)

E: 14700-96-0, 14835-24-6, 15723-23-6, 16547-50-5, 16885-04-4, 16887-00-6, 16904-11-3, 16904-12-4, 16999-02-3, 20337-89-7, 20499-73-4, 22537-15-1, 22537-27-5, 22541-73-7, 22541-74-8, 24203-47-2, 33944-49-9, 34937-26-3, 37352-90-2
clorine

Conditions

Conditions	Yield
In gas Kinetics; byproducts: SCl, Cl2; High Pressure; the reagent ions were generated in an electron impact high-pressure ion source contg. N2; the reagent ions were selected using a quadrupole massfilter before being injected into a drift region contg. He; 298 K; SCl, Cl2 were also obtained; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A 80% B 4% C 2% D 14% E n/a

...Expand

: 3982-91-0
trichlorothiophosphine

: 124-38-9
carbon dioxide

A: 14989-32-3
sulphur monochloride

B: 52826-97-8
PSCl2(1+)

C: PSCl3(1+)

D: O2*PSCl2(1+)

E: 75601-84-2
PCl2(1+)

Conditions

Conditions	Yield
In gas Kinetics; byproducts: Cl, CCl; High Pressure; the reagent ions were generated in an electron impact high-pressure ion source contg. CO2; the reagent ions were selected using a quadrupole mass filter before being injected into a drift region contg. He; at 298 K; Cl, CCl were also obtained; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A n/a B 80% C 11% D 3% E 6%

...Expand

: 3982-91-0
trichlorothiophosphine

: 95-48-7
ortho-cresol

: 91674-47-4
2-methylpheylphosphorodichloridate

Conditions

Conditions	Yield
Stage #1: ortho-cresol With sodium hydroxide In water at 0℃; Stage #2: trichlorothiophosphine With tetrabutylammomium bromide In dichloromethane; water at 0 - 20℃; for 5h;	80%

: 3982-91-0
trichlorothiophosphine

: 106-44-5
p-cresol

: 18961-95-0
p-tolyl phosphorodichloridothionate

Conditions

Conditions	Yield
Stage #1: p-cresol With sodium hydroxide In water at 0℃; Stage #2: trichlorothiophosphine With tetrabutylammomium bromide In dichloromethane; water at 0 - 20℃; for 5h;	76%

: 3982-91-0
trichlorothiophosphine

: 367-12-4
2-fluorophenol

: 1428326-54-8
C6H4Cl2FOPS

Conditions

Conditions	Yield
Stage #1: 2-fluorophenol With sodium hydroxide In water at 0℃; Stage #2: trichlorothiophosphine With tetrabutylammomium bromide In dichloromethane; water at 0 - 20℃; for 8h;	75%

: 3982-91-0
trichlorothiophosphine

: 80937-33-3
oxygen

A: 52826-97-8
PSCl2(1+)

B: PSCl3(1+)

C: O2*PSCl2(1+)

D: 14700-96-0, 14835-24-6, 15723-23-6, 16547-50-5, 16885-04-4, 16887-00-6, 16904-11-3, 16904-12-4, 16999-02-3, 20337-89-7, 20499-73-4, 22537-15-1, 22537-27-5, 22541-73-7, 22541-74-8, 24203-47-2, 33944-49-9, 34937-26-3, 37352-90-2
clorine

Conditions

Conditions	Yield
In gas Kinetics; High Pressure; the reagent ions were generated in an electron impact high-pressure ion source contg. O2/N2; the reagent ions were selected using a quadrupole mass filter before being injected into a drift region contg. helium carrier gas; at 298 K; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A 21% B 73% C 6% D n/a

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: 3982-91-0
trichlorothiophosphine

: 95-57-8
2-monochlorophenol

: 68591-34-4
phosphorodichloridothioic acid O-ortho-chlorophenyl ester

Conditions

Conditions	Yield
Stage #1: 2-monochlorophenol With sodium hydroxide In water at 0℃; Stage #2: trichlorothiophosphine With tetrabutylammomium bromide In dichloromethane; water at 0 - 20℃; for 8h;	72%

: 3982-91-0
trichlorothiophosphine

: 75-73-0
carbon tetrafluoride

A: 52826-97-8
PSCl2(1+)

B: CF2Cl3(1+)

C: PSCl3(1+)

D: 64710-27-6
Cl3FP(1+)

E: PCl3(1+)

Conditions

Conditions	Yield
In gas Kinetics; byproducts: CF2, CF2S, CClF2; High Pressure; ions were generated in an electron impact high-pressure ion source contg. CF4; the reagent ions were selected using a quadrupole mass filter before being injected into a region contg. He; at 298 K; CF2, CF2S, CClF2, CFS, PS were obtained; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A 4% B 2% C 69% D n/a E 25%

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: 3982-91-0
trichlorothiophosphine

: 2551-62-4
sulfur(VI) hexafluoride

A: 80799-96-8
ClS2(1+)

B: 52826-97-8
PSCl2(1+)

C: PSCl3(1+)

D: 64710-27-6
Cl3FP(1+)

E: PCl3(1+)

Conditions

Conditions	Yield
In gas Kinetics; byproducts: S2(1+), PFCl3, F; High Pressure; ions generated in an electron impact high-pressure ion source contg. SF6were selected using a quadrupole mass filter before being injected into a region contg. He; 298 K; S*PSCl3(1+), SF, SFCl, S2, ClF, ClP, FS2, S2 (1+), PFCl3, F were also obtained; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A 4% B 14% C 69% D 6% E 3%

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: 3982-91-0
trichlorothiophosphine

: 2551-62-4
sulfur(VI) hexafluoride

A: 43431-44-3
FS2(1+)

B: PSCl3(1+)

C: S*PSCl3(1+)

D: 64710-27-6
Cl3FP(1+)

E: PCl3(1+)

Conditions

Conditions	Yield
In gas Kinetics; byproducts: SF2, F2, PFCl3; High Pressure; the ions were generated in an electron impact high-pressure ion source contg. SF6; the ions were selected using a quadrupole mass filter before being injected into a drift region contg. He carrier gas; 298 K; SF2, F2, PFCl3, FS2, SSF2 were also obtained; monitoring by quadrupole mass spectrometer at the end of the flow tube;;	A 8% B 66% C 13% D 8% E 5%

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: 3982-91-0
trichlorothiophosphine

: 1310-73-2
sodium hydroxide

: trisodium thiophosphate

Conditions

Conditions	Yield
In water at 3 - 95℃; for 2.66667h; Product distribution / selectivity; Heating / reflux;	65%

: 3982-91-0
trichlorothiophosphine

: 75-73-0
carbon tetrafluoride

A: PFCl2(1+)

B: 38264-02-7
SCF(1+)

C: 75601-84-2
PCl2(1+)

D: 81128-92-9
PS(1+)

E: 40640-70-8
fluorodichloromethyl(1+)

Conditions

Yield

In gas Kinetics; byproducts: CFSCl3(1+), PFCl3(1+), CClS(1+); High Pressure; ions generated in an electron impact high-pressure source contg. CF4 were selected using a mass filter before being injected into a region contg. He; 298 K; CFSCl3(1+), PFCl3(1+), CClS(1+), CCl3F, PCl3, CClS, CClFS, PSCl, P, CS, PFCl2 were also obtained; monitoring by quadrupole mass spectrometer at the end of the flow tube;

A 15%
B 64%
C n/a
D n/a
E 9%

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: 3982-91-0
trichlorothiophosphine

: 7727-37-9
nitrogen

A: 52826-97-8
PSCl2(1+)

B: PSCl(1+)

C: PSCl3(1+)

D: 75601-84-2
PCl2(1+)

E: NS(1+)

Conditions

Conditions	Yield
In gas Kinetics; byproducts: Cl, N, PS(1+); High Pressure; ions generated in an electron impact high-pressure source contg. N2 wereselected using a quadrupole mass filter before being injected into a dr ift region contg. He; at 298 K; PS(1+), Cl, N, SCl, PCl3, Cl2, NCl3 werealso obtained; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A 62% B 1% C 16% D 15% E 5%

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: 3982-91-0
trichlorothiophosphine

: 12125-02-9
ammonium chloride

: 14475-36-6, 34859-01-3
dichlorothiophosphoric acid amide

Conditions

Conditions	Yield
for 20h; Reflux;	58.5%

: 3982-91-0
trichlorothiophosphine

: 1310-73-2
sodium hydroxide

: trisodium thiophosphate

Conditions

Conditions	Yield
In water for 0.5h; Product distribution / selectivity; Reflux;	56.5%
In water according to S.K. Yasuda, J.L. Lambert, Inorg. Synth. 1957, 5, 102; PSCl3 added to aq. NaOH; suspended in anhydr. methanol;	42%
In neat (no solvent)
In neat (no solvent)
In water react. of aq. NaOH and PSCl3;

: 3982-91-0
trichlorothiophosphine

: hydroxyferrocene

A: 206068-79-3
diferrocenyl chlorothiophosphonate

B: triferrocenyl thiophosphate

Conditions

Conditions	Yield
With NEt3 In tetrahydrofuran byproducts: NEt3HCl; Ar-atmosphere; mixing equimolar amt. of ferrocene derivative and NEt3, cooling to -78°C, slow addn. of 0.5 equiv. of PSCl3, stirring (room temp., overnight); filtration, evapn. (vac.), chromy. (SiO2, CH2Cl2);	A 49% B n/a

...Expand

: 3982-91-0
trichlorothiophosphine

: 75-73-0
carbon tetrafluoride

A: 52826-97-8
PSCl2(1+)

B: CF3(1+)*PSCl3=CF3*PSCl3(1+)

C: 64710-27-6
Cl3FP(1+)

D: 420-32-6
thiocarbonyl fluoride

E: 75-72-9
chlorotrifluoromethane

Conditions

Conditions	Yield
In gas Kinetics; High Pressure; the reagent ions were generated in an electron impact high-pressure ion source contg. CF4; the reagent ions were selected using a quadrupole mass filter before being injected into a drift region contg. helium carriergas; at 298 K; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A 48% B 44% C 8% D n/a E n/a

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: 3982-91-0
trichlorothiophosphine

: 10024-97-2
dinitrogen monoxide

A: 52826-97-8
PSCl2(1+)

B: PSCl3(1+)

C: NO*PSCl3(1+)

D: 75601-84-2
PCl2(1+)

E: 10102-43-9
nitrogen(II) oxide

Conditions

Conditions	Yield
In gas Kinetics; byproducts: ClNOS, ClNO; High Pressure; the reagent ions were generated in an electron impact high-pressure ion source contg. N2O; the reagent ions were selected using a quadrupole mass filter before being injected into a region contg. He; at 298 K; ClNO, ClNOS were also obtained; monitoring by quadrupole mass spectrometer at the end of the flow tube;	A 7% B 47% C 33% D 13% E n/a

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Thiophosphoryl chloride Specification

The Thiophosphoryl chloride, with the CAS registry number 3982-91-0 and EINECS registry number 223-622-6, has the systematic name of phosphorothioic trichloride. It is a kind of is a fuming, colorless liquid with a pungent odor, and belongs to the product category of Inorganic Chemicals. It is soluble in benzene, carbon tetrachloride, chloroform, and carbon disulfide. And the molecular formula of this chemical is Cl₃PS. What's more, it is used to prepare thiophosphorylate organic compounds, such as to produce insecticides.

The physical properties of Thiophosphoryl chloride are as following: (1)ACD/LogP: 0.99; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.994; (4)ACD/LogD (pH 7.4): 0.994; (5)ACD/BCF (pH 5.5): 3.355; (6)ACD/BCF (pH 7.4): 3.355 ; (7)#H bond acceptors: 0; (8)#H bond donors: 0; (9)#Freely Rotating Bonds: 0; (10)Polar Surface Area: 41.9 Å²; (11)Index of Refraction: 1.562; (12)Molar Refractivity: 30.73 cm³; (13)Molar Volume: 94.705 cm³; (14)Polarizability: 12.182×10^-24cm³; (15)Surface Tension: 57.747 dyne/cm; (16)Density: 1.789 g/cm³; (17)Flash Point: °CEnthalpy of ; (18)Vaporization: 34.789 kJ/mol; (19)Boiling Point: 125 °C at 760 mmHg; (20)Vapour Pressure: 15.031 mmHg at 25°C.

Preparation of Thiophosphoryl chloride: The most common and practical synthesis of the chemcial, which is also used in industrial manufacturing, is directly reacting phosphorus trichloride with excess sulfur at 180 °C.
PCl₃ + S → PSCl₃

Uses of Thiophosphoryl chloride: It can hydrolyze rapidly in basic or hydroxylic solutions, such as alcohols and amines, to produce thiophosphates.
PSCl₃ + 4H₂O → H₃PO₄ + H₂S + 3HCl
PSCl₃ + H₂O → HOP(S)Cl₂ + HCl

You should be cautious while dealing with this chemical. It is harmful if swallowed, and may also cause burns. It is also harmful to aquatic organisms, and may cause long-term adverse effects in the aquatic environment. Therefore, you had better take the following instructions: Wear suitable protective clothing, gloves and eye/face protection, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice; After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer); In case of accident or if you feel unwell, seek medical advice immediately (show label where possible); Avoid release to the environment. Refer to special instructions safety data sheet.

You can still convert the following datas into molecular structure:
(1)SMILES: P(=S)(Cl)(Cl)Cl
(2)InChI: InChI=1/Cl3PS/c1-4(2,3)5
(3)InChIKey: WQYSXVGEZYESBR-UHFFFAOYAE

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LC50	inhalation	400mg/m³ (400mg/m³)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(12), Pg. 53, 1987.
guinea pig	LD50	oral	520mg/kg (520mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(12), Pg. 53, 1987.
mouse	LC50	inhalation	630mg/m³ (630mg/m³)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(12), Pg. 53, 1987.
mouse	LD50	oral	700mg/kg (700mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(12), Pg. 53, 1987.
rat	LC50	inhalation	20ppm/4H (20ppm)		"Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972Vol. -, Pg. 17, 1972.
rat	LD50	oral	660mg/kg (660mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(12), Pg. 53, 1987.

Product Name

Thiophosphoryl chloride

Synthetic route

Thiophosphoryl chloride Specification

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