Trimethylamine hydrochloride supplier

Name
Trimethylamine hydrochloride
EINECS 209-810-0
CAS No. 593-81-7
Article Data62
CAS DataBase
Density 0.692g/cm3
Solubility Soluble in water
Melting Point 283-284 °C (dec.)(lit.)
Formula C₃H₁₀ClN
Boiling Point 2.8oC at 760 mmHg
Molecular Weight 95.5721
Flash Point
Transport Information
Appearance white to slightly cream crystalline powder
Safety 26-36-37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Methanamine,N,N-dimethyl-, hydrochloride (9CI);Trimethylamine, hydrochloride (8CI);Trimethylamine hydrochloric acid;Trimethylamine monohydrochloride;Trimethylammonium chloride;
PSA 3.24000
LogP 0.97980

Synthetic route

: 1184-78-7
trimethylamine-N-oxide

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 97-00-7
1-chloro-2,4-dinitro-benzene

A: 51-28-5
2,4-Dinitrophenol

B: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
for 24h; Ambient temperature;	A 97% B 98%

...Expand

: 1184-78-7
trimethylamine-N-oxide

: 97-00-7
1-chloro-2,4-dinitro-benzene

A: 51-28-5
2,4-Dinitrophenol

B: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
In N,N-dimethyl-formamide for 24h; Ambient temperature;	A 97% B 98%

...Expand

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
Stage #1: N,N-dimethyl-formamide dimethyl acetal With [1,4-bis(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; hydrogen In methanol at 25℃; under 30003 Torr; Autoclave; Stage #2: With hydrogenchloride In methanol; water Reagent/catalyst;	96%

: 50-00-0
formaldehyd

: 124-40-3
dimethyl amine

: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
With oxalic acid at 100 - 120℃; Eschweiler-Clarke methylation;	84%

: 67-56-1
methanol

: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
Stage #1: methanol With ammonium hydroxide; Ag/TiO2 at 25℃; for 10h; UV-irradiation; Stage #2: With hydrogenchloride In water	80%

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; lithium borohydride; chloro-trimethyl-silane In tetrahydrofuran for 24h; Ambient temperature;	72%
Stage #1: N,N-dimethyl-formamide With tris(bis(trimethylsilyl)amido)lanthanum(III); 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In benzene at 25℃; for 1h; Inert atmosphere; Glovebox; Stage #2: With hydrogenchloride In methanol at 0℃;	50%
Stage #1: N,N-dimethyl-formamide With tris((4,4-dimethyl-2-oxazolinyl)phenylborate) MgMe; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane Stage #2: With hydrogenchloride	18%

: 146475-62-9
cyclopropanesulfonyl-1-d chloride

: 67-63-0
isopropyl alcohol

: 75-50-3
trimethylamine

A: 593-81-7
trimethylamine hydrochloride

B: 146475-51-6
propan-2-yl cyclopropanesulfonate

C: N,N-dimethylcyclopropanesulfonamide-1-d

Conditions

Conditions	Yield
In dichloromethane at 25℃; for 36h;	A n/a B 11.7% C 27.4%

...Expand

: 88470-26-2
N,N-dimethoxyamine

: 75-50-3
trimethylamine

A: 593-81-7
trimethylamine hydrochloride

B: 75-57-0
tetramethlyammonium chloride

Conditions

Conditions	Yield
With tert-butylhypochlorite In diethyl ether 1) -78 deg C, 0.5 h, 2) -8 deg C, 24 h;	A 15.7% B 22.8%

...Expand

: Cl2B-N(CH3)2*N(CH3)3

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

A: 32882-72-7
Bis(trimethylsilyl)aminochlorodimethylaminoboran

B: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
In benzene stirring for 1 week in dry benzene; sepn. of trimethylamine hydrochloride and benzene;	A 16% B n/a
In benzene stirring for 1 week in dry benzene; sepn. of trimethylamine hydrochloride and benzene;	A 16% B n/a

...Expand

: 108-88-3
toluene

: 6001-87-2
methyl 3-chloropropionate

: 75-50-3
trimethylamine

A: 593-81-7
trimethylamine hydrochloride

B: 16332-33-5
(2-methoxycarbonylethyl)trimethylammonium chloride

Conditions

Conditions	Yield
at -5℃;

...Expand

: 67-56-1
methanol

: 6001-87-2
methyl 3-chloropropionate

: 75-50-3
trimethylamine

A: 593-81-7
trimethylamine hydrochloride

B: 16332-33-5
(2-methoxycarbonylethyl)trimethylammonium chloride

Conditions

Conditions	Yield
at -5℃;

...Expand

: 60-29-7
diethyl ether

: 6001-87-2
methyl 3-chloropropionate

: 75-50-3
trimethylamine

A: 593-81-7
trimethylamine hydrochloride

B: 16332-33-5
(2-methoxycarbonylethyl)trimethylammonium chloride

Conditions

Conditions	Yield
at -5℃;

...Expand

: 542-76-7
3-Chloropropionitrile

: 64-17-5
ethanol

: 75-50-3
trimethylamine

A: 593-81-7
trimethylamine hydrochloride

B: 107-13-1
acrylonitrile

...Expand

: 110-89-4
piperidine

: 120225-40-3
trimethyl-(3-oxo-3-phenyl-propenyl)-ammonium; chloride

A: 4452-12-4
1-phenyl-3-(piperidin-1-yl)prop-2-en-1-one

B: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
In acetonitrile at 25℃; Rate constant;

...Expand

: 110-89-4
piperidine

: 120225-39-0
trans-β-(p-nitrophenylsulfinyl)vinyltrimethylammonium chloride

A: 593-81-7
trimethylamine hydrochloride

B: p-nitrophenyl β-piperidylaminovinyl sulfoxide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 25℃; Rate constant; further solvent;

...Expand

: 110-89-4
piperidine

: 110065-18-4
trans-β-(p-nitrophenylsulfonyl)-vinyltrimethylammonium chloride

A: 107415-63-4
β-piperidyl aminovinyl sulfone

B: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
In acetonitrile at 25℃; Rate constant;

...Expand

: 67-56-1
methanol

: 56-93-9
benzyltrimethylammonium chloride

A: 593-81-7
trimethylamine hydrochloride

B: 103-29-7
1,1'-(1,2-ethanediyl)bisbenzene

C: 108-88-3
toluene

D: 100-51-6
benzyl alcohol

Conditions

Conditions	Yield
at 30℃; for 2h; Irradiation; Further byproducts given;	A 77 % Chromat. B 32 % Chromat. C 27 % Chromat. D 45 % Chromat.
With water at 30℃; for 2h; Irradiation; Further byproducts given;	A 77 % Chromat. B 10 % Chromat. C 27 % Chromat. D 45 % Chromat.
at 30℃; for 2h; Irradiation; Further byproducts given;	A 77 % Chromat. B 10 % Chromat. C 27 % Chromat. D 45 % Chromat.

...Expand

: 67-56-1
methanol

: 26050-72-6
(3,5-dimethoxybenzyl)trimethylammonium chloride

A: 4179-19-5
1,3-dimethoxy-5-methylbenzene

B: 73569-69-4
1-methylmethoxy-3,5-dimethoxybenzene

C: 506-59-2
N,N-dimethylammonium chloride

D: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
at 30℃; for 2h; Irradiation;	A 46 % Chromat. B 12 % Chromat. C 23 % Chromat. D 77 % Chromat.

...Expand

: 56-93-9
benzyltrimethylammonium chloride

A: 506-59-2
N,N-dimethylammonium chloride

B: 593-81-7
trimethylamine hydrochloride

C: 103-29-7
1,1'-(1,2-ethanediyl)bisbenzene

D: 108-88-3
toluene

E: 100-51-6
benzyl alcohol

Conditions

Conditions	Yield
With water In water at 30℃; for 2h; Mechanism; Irradiation; 253.7 nm;	A 23 % Chromat. B 77 % Chromat. C 10 % Chromat. D 27 % Chromat. E 45 % Chromat.

...Expand

: 56-93-9
benzyltrimethylammonium chloride

A: 593-81-7
trimethylamine hydrochloride

B: 103-29-7
1,1'-(1,2-ethanediyl)bisbenzene

C: 108-88-3
toluene

D: 100-51-6
benzyl alcohol

Conditions

Conditions	Yield
With water at 30℃; for 2h; Irradiation; Further byproducts given;	A 77 % Chromat. B 10 % Chromat. C 27 % Chromat. D 45 % Chromat.

...Expand

: 6608-47-5
vinylsulfonyl chloride

: 75-50-3
trimethylamine

A: 7465-57-8
2-(N,N,N-trimethylamino)ethanesulfonate

B: 593-81-7
trimethylamine hydrochloride

C: 58928-02-2
Ethenesulfonic acid; compound with trimethyl-amine

Conditions

Conditions	Yield
With potassium chloride; water In 1,2-dimethoxyethane at 1℃; Rate constant; Product distribution;

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: 98821-29-5
trans-1-propene-1-sulfonyl chloride

: 75-50-3
trimethylamine

A: 593-81-7
trimethylamine hydrochloride

B: 94129-00-7
C6H15NO3S

C: (E)-Propene-1-sulfonic acid; compound with trimethyl-amine

Conditions

Conditions	Yield
With potassium chloride; water In 1,2-dimethoxyethane at 1℃; Rate constant; Product distribution;

...Expand

: 50-00-0
formaldehyd

: ammonium chloride

A: 64-18-6
formic acid

B: 124-38-9
carbon dioxide

C: 506-59-2
N,N-dimethylammonium chloride

D: 593-81-7
trimethylamine hydrochloride

...Expand

: 7647-01-0
hydrogenchloride

: 64-17-5
ethanol

: 29124-44-5
hydroxymethyl-trimethyl-ammonium; chloride

: 593-81-7
trimethylamine hydrochloride

...Expand

: 7732-18-5
water

: 29124-44-5
hydroxymethyl-trimethyl-ammonium; chloride

: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
at 25℃; Geschwindigkeit der Zersetzung in Abhaengigkeit vom pH;

: 7732-18-5
water

: ethoxycarbonyl-trimethyl-ammonium; chloride

: 593-81-7
trimethylamine hydrochloride

polyoxymethylene: polyoxymethylene

: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
With ammonium chloride at 120 - 170℃; analog lassen sich andere Ammoniumsalze anwenden;

: 64-17-5
ethanol

: 138-24-9
phenyltrimethylammonium chloride

platinum black: platinum black

A: 110-82-7
cyclohexane

B: 593-81-7
trimethylamine hydrochloride

Conditions

Conditions	Yield
at 20 - 25℃; under 1520 - 2280 Torr; Hydrogenation;

...Expand

: 7732-18-5
water

: ethylsulfanylcarbonyl-trimethyl-ammonium; chloride

A: 124-38-9
carbon dioxide

B: 593-81-7
trimethylamine hydrochloride

C: 75-08-1
ethanethiol

...Expand

: 75-21-8
oxirane

: 593-81-7
trimethylamine hydrochloride

: 67-48-1
choline chloride

Conditions

Conditions	Yield
With sodium hydroxide at 24.9℃; Thermodynamic data; ΔrH1;	100%
With sodium hydroxide at 24.9℃;	100%

: 593-81-7
trimethylamine hydrochloride

: 603-33-8
triphenylbismuthane

: 7787-60-2
bismuth(III) chloride

Conditions

Conditions	Yield
byproducts: benzene; heating (CH3)3NHCl with triphenyl bismuth at 130°C (also in presence of ethanol);;	100%
byproducts: benzene; heating (CH3)3NHCl with triphenyl bismuth at 130°C (also in presence of ethanol);;	100%

: 105931-10-0
Hf(C5(CH3)5)2(CH2CH(CH3)CH2)

: 593-81-7
trimethylamine hydrochloride

: 156278-76-1
(Hf(C5(CH3)5)2(CH2CH(CH3)2))Cl

Conditions

Conditions	Yield
In dichloromethane-d2 to Hf-compd. and (HNMe3)Cl CD2Cl2 is vacuum transferred at -78°C(N2); tube is allowed to warm to 23°C and to stand with occasional shaking for 4 h;	100%

: 72708-53-3
tris(trimethylsilylmethyl)gallium

: 593-81-7
trimethylamine hydrochloride

A: 75-76-3
tetramethylsilane

B: 72709-13-8
Ga(3+)*2CH2Si(CH3)3(1-)*Cl(1-)*N(CH3)3=Ga(CH2Si(CH3)3)2Cl*N(CH3)3

Conditions

Conditions	Yield
In benzene under N2 or Ar mixt. in stoich. quantity stirred at room temp. for 2 h; volatile components removed by vac. distn., crude product sublimed at 32°C; elem. anal.;	A 100% B 98.5%

...Expand

: 16872-09-6
1,2-dicarba-closo-dodecaborane(12)

: 593-81-7
trimethylamine hydrochloride

: B9H11C2(2-)*2(CH3)3NH(1+)=[(CH3)3NH]2[B9H11C2]

Conditions

Conditions	Yield
With KOH In ethanol; water B compd. (34.7 mmol) added to EtOH soln. of KOH (104 mmol), refluxed for4 h (TLC control), evapd., dissolved (H2O), excess Me3NHCl added; ppt. filtered off, dried;	100%

: 593-81-7
trimethylamine hydrochloride

: 616-38-6
carbonic acid dimethyl ester

: 75-57-0
tetramethlyammonium chloride

Conditions

Conditions	Yield
With 1-ethyl-3-methylimidazolium bromide at 169.84℃; for 8h;	99%
With 1-ethyl-3-methylimidazolium bromide at 169.84℃; for 8h;

: 81476-76-8
dimethyl η5-cyclopentadienyl η5-pentamethylcyclopentadienyl zirconium

: 593-81-7
trimethylamine hydrochloride

: [Zr(η5-cyclopentadienyl)(η5-pentamethylcyclopentadienyl)(CH3)Cl]

Conditions

Conditions	Yield
In tetrahydrofuran stirring 4 days at room temp., evapn.; extn. (toluene), filtration, evapn., purity: 95% (NMR), analytically pure material obtained by repeated recrystn. (toluene/hexanes), elem. anal.;	99%
In tetrahydrofuran

: 249284-51-3
[U(N(CH2CH2NSiMe2But)2(CH2CH2NSiMeButCH2))]

: 593-81-7
trimethylamine hydrochloride

: 183054-80-0
U[N(CH2CH2NSi(CH3)2(C(CH3)3))3]Cl

Conditions

Conditions	Yield
In not given	99%

: 31422-93-2
8,8'-μ-methylcarboniodioxy-bis(1,2-dicarbollido)-3-cobalt(1-)ate

: 7732-18-5
water

: 593-81-7
trimethylamine hydrochloride

: trimethyl ammonium 8,8'-dihydroxy-bis(1,2-dicarbollido)-3-cobalt(1-)ate

Conditions

Conditions	Yield
With HCl In ethanol; water byproducts: CH3COOH; concd. HCl was added to suspn. of Co complex in aq. EtOH at 80°C;mixt. was shaken within ca. 30 min; Me3N*HCl in H2O was added; cooled overnight; septd.; crystd. at 80°C from MeCN by slow addition of CHCl3; cooled overnight; elem. anal.;	99%

...Expand

: 16853-85-3
lithium aluminium tetrahydride

: 593-81-7
trimethylamine hydrochloride

: 75-50-3
trimethylamine

: 17211-58-4, 50981-97-0, 60934-33-0
bis(trimethylamine)alane

Conditions

Conditions	Yield
In diethyl ether under N2 or Ar; LiAlH4 and Me3NHCl cooled to -78°C; Et2O added; stirred; warmed to room temp.; 1 h; solvent removed in vac.; NMe3 gas condensed; stirred for 20 min; sublimed at 50°C into flask at -78°C;	98%

...Expand

: cesium carba-closo-dodecaborate

: 593-81-7
trimethylamine hydrochloride

: CB11Cl12(1-)*C3H9N*H(1+)

Conditions

Conditions	Yield
Stage #1: cesium carba-closo-dodecaborate With antimonypentachloride at 180℃; for 168h; Inert atmosphere; Stage #2: trimethylamine hydrochloride In water-d2	98%

: 50-00-0
formaldehyd

: C4H24B22N2(2-)*2Cs(1+)

: 593-81-7
trimethylamine hydrochloride

: C5H25B22N2(1-)*C3H9N*H(1+)

Conditions

Conditions	Yield
Stage #1: formaldehyd With hydrogenchloride In 1,4-dioxane for 0.333333h; Inert atmosphere; Stage #2: C4H24B22N2(2-)*2Cs(1+) In 1,4-dioxane; ethyl acetate for 3h; Inert atmosphere; Stage #3: trimethylamine hydrochloride In 1,4-dioxane; water; ethyl acetate Inert atmosphere;	98%

...Expand

: di-μ-chlorobis[chloro(N,N'-bis-(2,6-(diisopropyl)phenyl)imidazol-2-ylidene)palladium]

: 593-81-7
trimethylamine hydrochloride

: C27H36Cl3N2Pd(1-)*C3H9N*H(1+)

Conditions

Conditions	Yield
In chloroform at 50℃; for 15h;	98%

: 1.2H4N2*C5H19B9NS(1-)*H(1+)

: 593-81-7
trimethylamine hydrochloride

: C3H9N*C5H19B9NS(1-)*H(1+)

Conditions

Conditions	Yield
In water	97%

: C4H24B22N2(2-)*2Cs(1+)

: 593-81-7
trimethylamine hydrochloride

: C4H24B22N2(1-)*C3H9N*H(1+)

Conditions

Conditions	Yield
In water Inert atmosphere;	97%

: C4H24B22N2(2-)*2Cs(1+)

: 593-81-7
trimethylamine hydrochloride

: 2C3H9N*C4H24B22N2(2-)*2H(1+)

Conditions

Conditions	Yield
In water Solvent;	97%

: 634196-69-3
1,2-diphenyl-3-fluoro-1,2-closo-dodecacarborane

: 593-81-7
trimethylamine hydrochloride

: [HN(CH3)3][3-fluoro-7,8-diphenyl-7,8-nido-undecacarborane]

Conditions

Conditions	Yield
With KOH; CO2 In ethanol N2, a soln. of B compd. refluxed with KOH for 72 h, treated wit CO2, volatiles removed (vac.), dissolved (H2O), a soln. of N compd. (excess) added; ppt. extrd. (CH2Cl2), dried (MgSO4), evapd., recrystd. (CH2Cl2); elem. anal.;	96.1%

: dipotassium 7-(2-carboxybenzoylaminoethyl)-7,8-dicarba-nido-undecaborate(10)

: 7732-18-5
water

: 593-81-7
trimethylamine hydrochloride

: bis(trimethylammonium) 7-(2-carboxybenzoylaminoethyl)-7,8-dicarba-nido-undecaborate(10) monohydrate

Conditions

Conditions	Yield
In not given cation metathesis react. of B compd. and Me3NHCl; recrystd. from water-EtOH: elem. anal.;	96%

...Expand

: 24034-98-8
1,2-(C6H5CH2)2-1,2-C2B10H10

: 593-81-7
trimethylamine hydrochloride

: [Me3NH][7,8-(C6H5CH2)2-nido-7,8-C2B9H10]

Conditions

Conditions	Yield
With KOH; HCl In methanol; water N2-atmosphere; stirring (0°C to room temp., 30 min), refluxing (overnight), evapn. H2O and HCl addn., pptn. on Me3NHCl addn.; filtering, washing (H2O), drying (vac.);	96%

: 2-(2-trimethylsilylethynyl)-3,4-(o-carborano)-2,5-dihydrofuran

: 593-81-7
trimethylamine hydrochloride

: 2-ethynyl-3,4-(dodecahydro-nido-undecadicarbaborato)-2,5-dihydrofuran*trimethylammonium

Conditions

Conditions	Yield
Stage #1: 2-(2-trimethylsilylethynyl)-3,4-(o-carborano)-2,5-dihydrofuran With sodium hydroxide In methanol for 1h; Reflux; Stage #2: trimethylamine hydrochloride With hydrogenchloride In water	96%

: potassium titanyl oxalate

: 10K(1+)*P2W17O61(10-)*99H2O = K10P2W17O61*99H2O

: 593-81-7
trimethylamine hydrochloride

: TiOP2W17O61(8-)*8(CH3)3NH(1+) = ((CH3)3NH)8TiOP2W17O61

Conditions

Conditions	Yield
In water a soln. of W-compound in NaOAc buffer (pH 5.25) was treated with Ti-compound at 65°C; stirred for 10 min; addn. of Me3NHCl at 25°C; precipitate washed (water), dried;;	95%

...Expand

: (Me3NH)(1-H-CB9Cl9)

: 100-39-0
benzyl bromide

: 593-81-7
trimethylamine hydrochloride

: (Me3NH)(1-C6H5CH2-CB9Cl9)

Conditions

Conditions	Yield
With n-BuLi; NaOH In tetrahydrofuran; diethyl ether; water byproducts: Me3N; to THF soln. (Me3NH)(1-H-CB9Cl9) was slowly added n-BuLi in hexane at 0°C, mixt. was stirred at room temp. for 4 h and refluxed for 4 h,Me3N was removed, THF soln. PhCH2Br was added at 0°C, soln. was stirred for 4 h at room temp. and; refluxed overnight, solvent was removed, residue was treated with 5 % aq. NaOH, extd. with Et2O and treated with aq. Me3NHCl;	95%

Yield

With n-BuLi; NaOH In tetrahydrofuran; diethyl ether; water byproducts: Me3N; to THF soln. (Me3NH)(1-H-CB9Cl9) was slowly added n-BuLi in hexane at 0°C, mixt. was stirred at room temp. for 4 h and refluxed for 4 h,Me3N was removed, THF soln. PhCH2Br was added at 0°C, soln. was stirred for 4 h at room temp. and; refluxed overnight, solvent was removed, residue was treated with 5 % aq. NaOH, extd. with Et2O and treated with aq. Me3NHCl;

95%

...Expand

: 19610-39-0
1.2-dicarba-closo-dodecaborano-tetrahydrofurane

: 593-81-7
trimethylamine hydrochloride

: [Me3NH][μ-7,8-CH2OCH2-7,8-C2B9H10]

Conditions

Conditions	Yield
With KOH In ethanol (N2); KOH added to a soln. of B compd., refluxed overnight; solvent-removed, dissolved in H2O, pptd. ((CH3)3NHCl), filtered, washed (H2O), dried (vac.); elem. anal.;	95%

: C4H17B9NS(1-)*1.4H4N2*H(1+)

: 593-81-7
trimethylamine hydrochloride

: C4H17B9NS(1-)*C3H9N*H(1+)

Conditions

Conditions	Yield
In water	95%

: 3344-70-5
1,12-dibromododecane

: 593-81-7
trimethylamine hydrochloride

: 1674-82-4
N,N,N,N',N',N'-hexamethyldodecane-1,12-diammonium dibromide

Conditions

Conditions	Yield
With sodium hydroxide In methanol for 12h; Heating / reflux;	94%

: 802892-30-4
1-Me2NCH2CH2-1,2-C2B10H11

: 593-81-7
trimethylamine hydrochloride

: 7-Me2N(H)CH2CH2-7,8-C2B9H11

Conditions

Conditions	Yield
With KOH In water (N2); addn. of methanol to a mixt. of boron compd. and KOH with stirringat 0°C, warming to room temp., stirring for 30 min, reflux overn ight, evapn., addn. of water, addn. of aq. ammonium salt; filtration, washing ppt. with water, n-hexane, drying in vac., recrystn.(ethanol); elem. anal.;	94%

: [Me3NH][1-H-CB11Cl11]

: 593-81-7
trimethylamine hydrochloride

: 75-03-6
ethyl iodide

: Me3NH[EthylCB11Cl11]

Conditions

Yield

With tert-butoxide In tert-butyl alcohol a soln. of B-contg. compd. in tert-butanol was treated with KOBu(t) (3.5equivs.) for 30 min at 30°C; the volatiles were removed; the res idue was redissolved in tert-butanol and treated with EtI (7 equivs.) at30°C for 1 h; the volatiles were removed, the residue dissolved in H2O; addn. of concd. HCl (2 drops) and Me3NHCl (2.5 equivs.); mass- and (11)B NMR spectra studies;

94%

...Expand

Trimethylamine hydrochloride Chemical Properties

Molecular structure of Trimethylamine hydrochloride (CAS NO.593-81-7) is:

Product Name: Trimethylamine hydrochloride
CAS Registry Number: 593-81-7
IUPAC Name: N,N-dimethylmethanamine hydrochloride
Molecular Weight: 95.5712 [g/mol]
Molecular Formula: C₃H₁₀ClN
H-Bond Donor: 1
H-Bond Acceptor: 1
EINECS: 209-810-0
Melting Point: 283-284 °C (dec.)(lit.)
Storage temp.: 2-8°C
Water Solubility: Soluble
Sensitive: Hygroscopic
Enthalpy of Vaporization: 22.94 kJ/mol
Boiling Point: 2.8 °C at 760 mmHg
Vapour Pressure: 1720 mmHg at 25°C

Trimethylamine hydrochloride Uses

Trimethylamine hydrochloride (CAS NO.593-81-7) is used as a raw material of choline chloride, ion exchange resins, tetramethyl ammonium hydroxide, oil field chemicals, quaternary ammonium compounds, cationic starch reagents, phase transfer catalyst, pesticides as well as a warning agent for natural gas and flotation agent.

Trimethylamine hydrochloride Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	325mg/kg (325mg/kg)		Medicina et Pharmacologia Experimentalis. Vol. 16, Pg. 529, 1967.

Trimethylamine hydrochloride Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 1
RTECS: YH2700000
F: 3-10
HS Code: 29211190

Trimethylamine hydrochloride Specification

Trimethylamine hydrochloride , its cas register number is 593-81-7. It also can be called Trimethylammonium chloride ; Methanamine, N,N-dimethyl-, hydrochloride .It is a white to slightly cream crystalline powder.

Product Name

Trimethylamine hydrochloride

Synthetic route

Trimethylamine hydrochloride Chemical Properties

Trimethylamine hydrochloride Uses

Trimethylamine hydrochloride Toxicity Data With Reference

Trimethylamine hydrochloride Safety Profile

Trimethylamine hydrochloride Specification

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