Product Name

  • Name

    1,3-Dichloropropane

  • EINECS 205-531-3
  • CAS No. 142-28-9
  • Article Data69
  • CAS DataBase
  • Density 1.188 g/cm3
  • Solubility water: 0.8 g/L (20 °C)
  • Melting Point -99 ºC
  • Formula C3H6Cl2
  • Boiling Point 120.4 °C at 760 mmHg
  • Molecular Weight 112.987
  • Flash Point 32.2 °C
  • Transport Information UN 1993 3/PG 2
  • Appearance clear colourless liquid
  • Safety 9-16-29-33-24-61-26-45-36/37-7
  • Risk Codes 11-20-20/22-52/53-36/37/38-23/24/25-36-20/21/22
  • Molecular Structure Molecular Structure of 142-28-9 (1,3-Dichloropropane)
  • Hazard Symbols FlammableF,HarmfulXn,ToxicT
  • Synonyms NSC 6204;R 270fa;Trimethylene dichloride;
  • PSA 0.00000
  • LogP 1.85410

Synthetic route

trimethyleneglycol
504-63-2

trimethyleneglycol

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With hydrogenchloride; ammonium chloride In water at 60 - 107℃; for 3h;97.2%
With hydrogenchloride at 80℃; for 48h;10%
With thionyl chloride
cyclopropane
75-19-4

cyclopropane

A

cyclopropyl chloride
7393-45-5

cyclopropyl chloride

B

1,1-dichlorocyclopropane
2088-35-9

1,1-dichlorocyclopropane

C

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

D

3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

Conditions
ConditionsYield
With chlorine; silicon tetrafluoride at 600℃; Product distribution; Irradiation;A 83.5%
B 4%
C n/a
D 2.6%
trimethyleneglycol
504-63-2

trimethyleneglycol

A

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

B

1-chloro-3-hydroxypropane
627-30-5

1-chloro-3-hydroxypropane

Conditions
ConditionsYield
With tetrachloromethane; triphenylphosphine In acetonitrile Product distribution; Mechanism;A 16%
B 75%
With hydrogenchloride at 100℃;
With hydrogenchloride
With tert-butylhypochlorite; triphenylphosphine In chloroform Product distribution; 1.) -70 deg C, 2.) RT, 3.) reflux, 24 h;
cyclopropane
75-19-4

cyclopropane

A

1,1,3-trichloropropane
20395-25-9

1,1,3-trichloropropane

B

1,2,3-trichloropropane
96-18-4

1,2,3-trichloropropane

C

cyclopropyl chloride
7393-45-5

cyclopropyl chloride

D

1,1-dichlorocyclopropane
2088-35-9

1,1-dichlorocyclopropane

E

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With chlorine In trichlorofluoromethane at 21℃; for 0.0833333h; Product distribution; Mechanism; Irradiation; also 1,3-dichloropropane; var. solvents (also in the gas phase);A 13%
B 8.7%
C 11%
D 0.4%
E 67%
trimethyleneglycol
504-63-2

trimethyleneglycol

A

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

B

2-chloro-1,3,2-dioxaphosphinane
6362-89-6

2-chloro-1,3,2-dioxaphosphinane

C

3-chloro-n-propyl-dichlorophosphite

3-chloro-n-propyl-dichlorophosphite

Conditions
ConditionsYield
With phosphorus trichloride In dichloromethane for 2h; Ambient temperature;A n/a
B 48%
C 5%
trimethylene oxide
503-30-0

trimethylene oxide

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With phosphorus pentachloride
3-chloropropyl p-toluenesulfonate
632-02-0

3-chloropropyl p-toluenesulfonate

diethyl ether
60-29-7

diethyl ether

butylmagnesium chloride

butylmagnesium chloride

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

formaldehyd
50-00-0

formaldehyd

ethene
74-85-1

ethene

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With hydrogenchloride at 149 - 154℃; under 540598 - 680345 Torr;
propane
74-98-6

propane

A

1,2-Dichloropropane
26198-63-0, 78-87-5

1,2-Dichloropropane

B

2,2-dichloropropane
594-20-7

2,2-dichloropropane

C

1,1-dichloropropane
78-99-9

1,1-dichloropropane

D

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
at 400℃; Product distribution; thermische Chlorierung;
at 400℃; Product distribution; thermische Chlorierung;
ethene
74-85-1

ethene

dichloromethane
75-09-2

dichloromethane

A

1,5-dichloropentane
628-76-2

1,5-dichloropentane

B

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With water; dibenzoyl peroxide at 200℃; under 55163.1 - 73550.8 Torr;
1-Chloropropane
540-54-5

1-Chloropropane

A

1,2-Dichloropropane
26198-63-0, 78-87-5

1,2-Dichloropropane

B

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With sulfuryl dichloride; 1,2-dichloro-benzene; dibenzoyl peroxide
With sulfuryl dichloride; dilauryl peroxide; chlorobenzene
With sulfuryl dichloride; dilauryl peroxide; 1,2-dichloro-benzene
1,3-Diiodopropane
627-31-6

1,3-Diiodopropane

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With water; silver(I) chloride
benzyl chloride
100-44-7

benzyl chloride

trimethyleneglycol
504-63-2

trimethyleneglycol

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With triphenyl phosphite at 170 - 180℃;
ethanol
64-17-5

ethanol

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

A

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

B

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With antimonypentachloride
With mercury dichloride
1-chloro-3-hydroxypropane
627-30-5

1-chloro-3-hydroxypropane

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With thionyl chloride
phosgene
75-44-5

phosgene

3-methoxypropylamine
5332-73-0

3-methoxypropylamine

1-Chloronaphthalene
90-13-1

1-Chloronaphthalene

A

3-Chloropropyl isocyanate
13010-19-0

3-Chloropropyl isocyanate

B

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
at 140 - 150℃; das Hydrochlorid reagiert;
1-Chloropropane
540-54-5

1-Chloropropane

A

1,2-Dichloropropane
26198-63-0, 78-87-5

1,2-Dichloropropane

B

1,1-dichloropropane
78-99-9

1,1-dichloropropane

C

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With chlorine In 1,2-dichloro-benzene at 0℃; Product distribution; oth. temperatures;
With N-chloropiperidine; 2,2'-azobis(isobutyronitrile) In trifluoroacetic acid at 30℃; Product distribution; Rate constant; Irradiation; relative rate constants, position selectivity, substrate selectivity;
With chlorine In benzene at -10.1℃; Product distribution; dependence of the selectivity of chlorination on the conc. of benzene;
With sulfuryl dichloride; dibenzoyl peroxide
With chlorine Ambient temperature; Irradiation;
1,1,3-trichloropropane
20395-25-9

1,1,3-trichloropropane

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With triethylsilane; decacarbonyldirhenium(0) at 160℃; for 5h;48 % Chromat.
With triethylsilane; Re(CO)10 at 159.9℃; for 5h; Rate constant; other catalyst, time, temperature;20 % Chromat.
cyclopropane
75-19-4

cyclopropane

A

hydrogenchloride
7647-01-0

hydrogenchloride

B

cyclopropyl chloride
7393-45-5

cyclopropyl chloride

C

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With chlorine at -263.2℃; Quantum yield; Irradiation; further temps.;
trimethyleneglycol
504-63-2

trimethyleneglycol

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With hydrogenchloride; ammonium chloride In water at 60 - 107℃; for 3h;97.2%
With hydrogenchloride at 80℃; for 48h;10%
With thionyl chloride
cyclopropane
75-19-4

cyclopropane

A

cyclopropyl chloride
7393-45-5

cyclopropyl chloride

B

1,1-dichlorocyclopropane
2088-35-9

1,1-dichlorocyclopropane

C

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

D

3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

Conditions
ConditionsYield
With chlorine; silicon tetrafluoride at 600℃; Product distribution; Irradiation;A 83.5%
B 4%
C n/a
D 2.6%
trimethyleneglycol
504-63-2

trimethyleneglycol

A

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

B

1-chloro-3-hydroxypropane
627-30-5

1-chloro-3-hydroxypropane

Conditions
ConditionsYield
With tetrachloromethane; triphenylphosphine In acetonitrile Product distribution; Mechanism;A 16%
B 75%
With hydrogenchloride at 100℃;
With hydrogenchloride
With tert-butylhypochlorite; triphenylphosphine In chloroform Product distribution; 1.) -70 deg C, 2.) RT, 3.) reflux, 24 h;
cyclopropane
75-19-4

cyclopropane

A

1,1,3-trichloropropane
20395-25-9

1,1,3-trichloropropane

B

1,2,3-trichloropropane
96-18-4

1,2,3-trichloropropane

C

cyclopropyl chloride
7393-45-5

cyclopropyl chloride

D

1,1-dichlorocyclopropane
2088-35-9

1,1-dichlorocyclopropane

E

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With chlorine In trichlorofluoromethane at 21℃; for 0.0833333h; Product distribution; Mechanism; Irradiation; also 1,3-dichloropropane; var. solvents (also in the gas phase);A 13%
B 8.7%
C 11%
D 0.4%
E 67%
trimethyleneglycol
504-63-2

trimethyleneglycol

A

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

B

2-chloro-1,3,2-dioxaphosphinane
6362-89-6

2-chloro-1,3,2-dioxaphosphinane

C

3-chloro-n-propyl-dichlorophosphite

3-chloro-n-propyl-dichlorophosphite

Conditions
ConditionsYield
With phosphorus trichloride In dichloromethane for 2h; Ambient temperature;A n/a
B 48%
C 5%
trimethylene oxide
503-30-0

trimethylene oxide

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With phosphorus pentachloride
3-chloropropyl p-toluenesulfonate
632-02-0

3-chloropropyl p-toluenesulfonate

diethyl ether
60-29-7

diethyl ether

butylmagnesium chloride

butylmagnesium chloride

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

formaldehyd
50-00-0

formaldehyd

ethene
74-85-1

ethene

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With hydrogenchloride at 149 - 154℃; under 540598 - 680345 Torr;
propane
74-98-6

propane

A

1,2-Dichloropropane
26198-63-0, 78-87-5

1,2-Dichloropropane

B

2,2-dichloropropane
594-20-7

2,2-dichloropropane

C

1,1-dichloropropane
78-99-9

1,1-dichloropropane

D

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
at 400℃; Product distribution; thermische Chlorierung;
at 400℃; Product distribution; thermische Chlorierung;
ethene
74-85-1

ethene

dichloromethane
75-09-2

dichloromethane

A

1,5-dichloropentane
628-76-2

1,5-dichloropentane

B

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With water; dibenzoyl peroxide at 200℃; under 55163.1 - 73550.8 Torr;
1-Chloropropane
540-54-5

1-Chloropropane

A

1,2-Dichloropropane
26198-63-0, 78-87-5

1,2-Dichloropropane

B

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With sulfuryl dichloride; 1,2-dichloro-benzene; dibenzoyl peroxide
With sulfuryl dichloride; dilauryl peroxide; chlorobenzene
With sulfuryl dichloride; dilauryl peroxide; 1,2-dichloro-benzene
1,3-Diiodopropane
627-31-6

1,3-Diiodopropane

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With water; silver(I) chloride
benzyl chloride
100-44-7

benzyl chloride

trimethyleneglycol
504-63-2

trimethyleneglycol

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With triphenyl phosphite at 170 - 180℃;
ethanol
64-17-5

ethanol

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

A

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

B

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With antimonypentachloride
With mercury dichloride
1-chloro-3-hydroxypropane
627-30-5

1-chloro-3-hydroxypropane

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With thionyl chloride
phosgene
75-44-5

phosgene

3-methoxypropylamine
5332-73-0

3-methoxypropylamine

1-Chloronaphthalene
90-13-1

1-Chloronaphthalene

A

3-Chloropropyl isocyanate
13010-19-0

3-Chloropropyl isocyanate

B

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
at 140 - 150℃; das Hydrochlorid reagiert;
1-Chloropropane
540-54-5

1-Chloropropane

A

1,2-Dichloropropane
26198-63-0, 78-87-5

1,2-Dichloropropane

B

1,1-dichloropropane
78-99-9

1,1-dichloropropane

C

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With chlorine In 1,2-dichloro-benzene at 0℃; Product distribution; oth. temperatures;
With N-chloropiperidine; 2,2'-azobis(isobutyronitrile) In trifluoroacetic acid at 30℃; Product distribution; Rate constant; Irradiation; relative rate constants, position selectivity, substrate selectivity;
With chlorine In benzene at -10.1℃; Product distribution; dependence of the selectivity of chlorination on the conc. of benzene;
With sulfuryl dichloride; dibenzoyl peroxide
With chlorine Ambient temperature; Irradiation;
1,1,3-trichloropropane
20395-25-9

1,1,3-trichloropropane

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With triethylsilane; decacarbonyldirhenium(0) at 160℃; for 5h;48 % Chromat.
With triethylsilane; Re(CO)10 at 159.9℃; for 5h; Rate constant; other catalyst, time, temperature;20 % Chromat.
cyclopropane
75-19-4

cyclopropane

A

hydrogenchloride
7647-01-0

hydrogenchloride

B

cyclopropyl chloride
7393-45-5

cyclopropyl chloride

C

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With chlorine at -263.2℃; Quantum yield; Irradiation; further temps.;
1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

A

1,2-Dichloropropane
26198-63-0, 78-87-5

1,2-Dichloropropane

B

1,2-Dibromopropane
78-75-1

1,2-Dibromopropane

C

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

D

allyl bromide
106-95-6

allyl bromide

E

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

F

3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

Conditions
ConditionsYield
aluminum oxide at 160℃; Mechanism; Product distribution; different temperature;
trimethylene oxide
503-30-0

trimethylene oxide

phosphorus pentachloride
10026-13-8, 874483-75-7

phosphorus pentachloride

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

2-methyl-[1,3]dioxane
626-68-6

2-methyl-[1,3]dioxane

phosphorus pentachloride
10026-13-8, 874483-75-7

phosphorus pentachloride

A

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

B

acetaldehyde
75-07-0

acetaldehyde

antimonypentachloride
7647-18-9

antimonypentachloride

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

3-chloropropyl p-toluenesulfonate
632-02-0

3-chloropropyl p-toluenesulfonate

alkyl magnesium chloride

alkyl magnesium chloride

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
With diethyl ether
trimethylene

trimethylene

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

Conditions
ConditionsYield
beim Chlorieren;
1-Chloropropane
540-54-5

1-Chloropropane

A

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

B

1,1-dichloro-propane and 1,2-dichloro-propane

1,1-dichloro-propane and 1,2-dichloro-propane

Conditions
ConditionsYield
With chlorine at 340℃;
With chlorine at 100℃; in der Gasphase unter der Einwirkung von Licht;
With chlorine at -78℃; in der fluessiger Phase unter der Einwirkung von Licht;
propane
74-98-6

propane

A

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

B

1.1-dichloro-propane, 1.2-dichloro-propane and 2.2-dichloro-propane

1.1-dichloro-propane, 1.2-dichloro-propane and 2.2-dichloro-propane

Conditions
ConditionsYield
With chlorine at 400℃;
With tetrachloromethane; chlorine at 200℃; under 29420.3 - 36775.4 Torr;
With chlorine at 400℃;
hydrogenchloride
7647-01-0

hydrogenchloride

3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

dibenzoyl peroxide
94-36-0

dibenzoyl peroxide

A

1,2-Dichloropropane
26198-63-0, 78-87-5

1,2-Dichloropropane

B

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

(c-C6H11)2SbLi
1013-90-7

(c-C6H11)2SbLi

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

1,3-bis(dicyclohexylstibino)propane
1057-24-5

1,3-bis(dicyclohexylstibino)propane

Conditions
ConditionsYield
In tetrahydrofuran; diethyl ether addn. of 1,3-dichloropropane in THF over 30 min to a (c-C6H11)2SbLi soln. in ether at -45°C; mixt. treated with aq. NH4Cl, evapn. of the ether;99%
In tetrahydrofuran; diethyl ether addn. of 1,3-dichloropropane in THF over 30 min to a (c-C6H11)2SbLi soln. in ether at -45°C; mixt. treated with aq. NH4Cl, evapn. of the ether;99%
1-methyl-1H-imidazole
616-47-7

1-methyl-1H-imidazole

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

1,1'-dimethyl-3,3'-(1,3-trimethylene)bisimidazolium dichloride

1,1'-dimethyl-3,3'-(1,3-trimethylene)bisimidazolium dichloride

Conditions
ConditionsYield
In chloroform at 60℃; under 14251400 Torr; for 24h; Pressure; Menshutkin Reaction; High pressure; Autoclave;99%
at 110℃; for 6h; neat (no solvent);92%
In methanol for 24h; Reflux;
In methanol for 24h; Reflux;
1,2-dimethyl-1H-imidazole
1739-84-0

1,2-dimethyl-1H-imidazole

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

1,3-bis(1,2-dimethylimidazolium-3-yl)propane dichloride

1,3-bis(1,2-dimethylimidazolium-3-yl)propane dichloride

Conditions
ConditionsYield
In chloroform at 60℃; under 14251400 Torr; for 24h; Kinetics; Pressure; Time; Menshutkin Reaction; High pressure; Autoclave;99%
1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

dicyclohexylphosphane
829-84-5

dicyclohexylphosphane

1,3-bis(dicyclohexylphosphine)propane
103099-52-1

1,3-bis(dicyclohexylphosphine)propane

Conditions
ConditionsYield
Stage #1: dicyclohexylphosphane With n-butyllithium In tetrahydrofuran at -78 - 20℃; for 1.25h; Inert atmosphere; Schlenk technique;
Stage #2: 1,3-Dichloropropane In tetrahydrofuran at -78 - 20℃; for 2h; Inert atmosphere; Schlenk technique;
97%
phthalimide
136918-14-4

phthalimide

ethyl acetoacetate
141-97-9

ethyl acetoacetate

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

ethyl 2-acetyl-5-(1,3-dioxo-1,3-dihydro-2-isoindolyl)pentanoate
55747-45-0

ethyl 2-acetyl-5-(1,3-dioxo-1,3-dihydro-2-isoindolyl)pentanoate

Conditions
ConditionsYield
Stage #1: phthalimide With potassium carbonate In acetonitrile at 20℃; for 0.5h;
Stage #2: 1,3-Dichloropropane With sodium iodide In acetonitrile at 58 - 60℃; for 5.5h;
Stage #3: ethyl acetoacetate In acetonitrile at 20℃; for 7h; Reagent/catalyst;
96.2%
theobromine /
83-67-0

theobromine /

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

1-(3-chloropropyl)-3,7-dimethyl-2,3,6,7-tetrahydro-1H-2,6-purinedione
74409-52-2

1-(3-chloropropyl)-3,7-dimethyl-2,3,6,7-tetrahydro-1H-2,6-purinedione

Conditions
ConditionsYield
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride for 2h; Heating;96%
sodium formate
141-53-7

sodium formate

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

1,3-propanediol diformate
1727-40-8

1,3-propanediol diformate

Conditions
ConditionsYield
tetrabutylammomium bromide at 115℃; for 1.5h;96%
1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione
61717-82-6

1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione

propane-1,3-diyl bis(2-iodobenzoate)

propane-1,3-diyl bis(2-iodobenzoate)

Conditions
ConditionsYield
With tetrabutylammomium bromide In dimethyl sulfoxide at 80℃;96%
4-Methoxyphenylacetic acid
104-01-8

4-Methoxyphenylacetic acid

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

3-chloropropyl 2-(4-methoxyphenyl)acetate
98128-28-0

3-chloropropyl 2-(4-methoxyphenyl)acetate

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 45℃; for 3h;96%
dimethylenecyclourethane
497-25-6

dimethylenecyclourethane

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

3-(3-chloro-1-propyl)-2-oxazolidinone
10127-86-3

3-(3-chloro-1-propyl)-2-oxazolidinone

Conditions
ConditionsYield
With NaH In dichloromethane; N,N-dimethyl-formamide95%
sodium p-aminobenzoate
555-06-6

sodium p-aminobenzoate

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

propane-1,3-diyl bis(4-aminobenzoate)
57609-64-0

propane-1,3-diyl bis(4-aminobenzoate)

Conditions
ConditionsYield
In N-methyl-acetamide; water95%
With sodium carbonate; dimethyl sulfoxide; 1,2-dichloro-ethane In water91.5%

1,3-Dichloropropane Consensus Reports

Reported in EPA TSCA Inventory.

1,3-Dichloropropane Specification

The IUPAC name of this product is 1,3-dichloropropane. With the CAS registry number 142-28-9, it is also named as Trimethylene dichloride; Propane, 1,3-dichloro-. The product's categories are alpha,omega-bifunctional alkanes; alpha,omega-dichloroalkanes; monofunctional & alpha,omega-bifunctional alkanes; analytical chemistry; standard solution of volatile organic compounds for water & soil analysis; standard solutions (VOC); volatiles / semivolatiles. It is clear colourless liquid with a sweet odor. And it is highly flammable, so keep it away from sources of ignition. In addition, 1,3-Dichloropropane belongs to halogenated aliphatic compounds which are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. This material is incompatible with strong oxidizing and reducing agents. Also, it is incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 2.00; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2; (4)ACD/LogD (pH 7.4): 2; (5)ACD/BCF (pH 5.5): 19.51; (6)ACD/BCF (pH 7.4): 19.51; (7)ACD/KOC (pH 5.5): 291.83; (8)ACD/KOC (pH 7.4): 291.83; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)Index of Refraction: 1.422; (12)Molar Refractivity: 25.64 cm3; (13)Molar Volume: 100.8 cm3; (14)Polarizability: 10.16×10-24 cm3; (15)Surface Tension: 26.3 dyne/cm; (16)Enthalpy of Vaporization: 35.18 kJ/mol; (17)Vapour Pressure: 18.3 mmHg at 25°C; (18)Rotatable Bond Count: 2; (19)Exact Mass: 111.984656; (20)MonoIsotopic Mass: 111.984656; (21)Heavy Atom Count: 5.

Uses of 1,3-Dichloropropane: It can be used for organic synthesis intermediates and solvents. And it is also used as standard materials of solvent, detergent and chromatographic analysis. In addition, it reacts with mercaptoacetic acid to get 3,7-dithia-nonanedioic acid. This reaction needs reagent NaOH and solvent H2O
ethanol by heating. The reaction time is 16 hours. The yield is 74 %.

When you are using this chemical, please be cautious about it as the following:
It is harmful by inhalation, in contact with skin and if swallowed. And it is also irritating to eyes, respiratory system and skin. Furthermore, it is harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment, so people should avoid release to the environment. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing and gloves. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

People can use the following data to convert to the molecule structure. 
1. SMILES: ClCCCCl;
2. InChI: InChI=1/C3H6Cl2/c4-2-1-3-5/h1-3H2.

The following are the toxicity data which has been tested.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo oral 3gm/kg (3000mg/kg) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA

LIVER: OTHER CHANGES

BLOOD: HEMORRHAGE
American Journal of Hygiene. Vol. 16, Pg. 325, 1932.
mouse LD50 unreported 3600mg/kg (3600mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Eisei Kagaku. Hygienic Chemistry. Vol. 28, Pg. P31, 1982.

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