Pyrocatechol supplier | CasNO.120-80-9

Name
Pyrocatechol
EINECS 204-427-5
CAS No. 120-80-9
Article Data775
CAS DataBase
Density 1.275 g/cm³
Solubility water: 430 g/L (20 ºC)
Melting Point 103-106 ºC
Formula C₆H₆O₂
Boiling Point 245.5 ºC at 760 mmHg
Molecular Weight 110.112
Flash Point 137.2 ºC
Transport Information UN 2811 6.1/PG 3
Appearance off-white powder
Safety 22-26-37
Risk Codes 21/22-36/38
Molecular Structure
Hazard Symbols Xn
Synonyms Pyrocatechol(8CI);1,2-Dihydroxybenzene;2-Hydroxyphenol;C.I. 76500;C.I. Oxidation Base 26;Catechol;
PSA 40.46000
LogP 1.09780

Synthetic route

: 108-95-2
phenol

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With dihydrogen peroxide; MgAlZr0.1-HT In Petroleum ether at 79.9℃; for 8h;	100%
With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In methanol; chloroform at -25℃; for 0.333333h;	97%
With tert.-butylhydroperoxide In water; acetonitrile at 70℃; for 6h; Catalytic behavior; Temperature; Solvent;	89%

: 2171-74-6
1,3-benzodioxol-2-one

: 67-63-0
isopropyl alcohol

A: 6482-34-4
bis-2-propyl carbonate

B: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With sodium methylate In neat (no solvent) at 100℃; under 1500.15 Torr; for 5h; Inert atmosphere; Autoclave;	A 67% B 100%
With sodium methylate at 100℃; for 5h; Temperature; Autoclave; Inert atmosphere;	A 90 %Chromat. B n/a

...Expand

: 274-09-9
Methylenedioxybenzene

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With 1,3-dimethyl-2-imidazolidinone; sodium hexamethyldisilazane In tetrahydrofuran at 185℃; for 12h; further reagent: LDA;	99%
With sodium di(ethyl)amine In N,N,N,N,N,N-hexamethylphosphoric triamide; benzene for 12h; Heating;	85%
With aluminium(III) iodide In carbon disulfide for 7h; Heating; Var. solvent, time and substrate reagent ratio;	80%

: 90-05-1
2-methoxy-phenol

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
Stage #1: 2-methoxy-phenol With pyridine; iodine; aluminium In acetonitrile for 18h; Reflux; Stage #2: With hydrogenchloride In water; acetonitrile at 20℃;	99%
With hydrogenchloride In water at 250℃; under 37503.8 Torr; for 3h; Reagent/catalyst; Autoclave; Inert atmosphere; Green chemistry;	97%
With aluminium(III) iodide; calcium oxide In acetonitrile at 80℃; for 18h; Reagent/catalyst;	94%

: 14005-14-2
2,2-dimethyl-1,3-benzodioxole

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 18h; Catalytic behavior; Reagent/catalyst; Solvent;	99%
With indium(III) triflate In water; acetonitrile at 120℃; for 0.5h; Microwave irradiation;	91%
With sodium di(ethyl)amine In N,N,N,N,N,N-hexamethylphosphoric triamide; benzene for 12h; Heating;	88%

: 116915-91-4
6H,11H-dibenzo<14>dioxocin

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With hydrogen; palladium hydroxide - carbon In ethanol under 760 Torr;	99%

: 583-55-1
1-Bromo-2-iodobenzene

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With glycolic Acid; copper hydroxide; sodium hydroxide In water; dimethyl sulfoxide at 120℃; for 6h; Inert atmosphere; Schlenk technique;	99%
With β-D-glucose; copper(II) acetate monohydrate; potassium hydroxide In water; dimethyl sulfoxide at 20 - 120℃; for 16h;	83%

: 90-02-8
salicylaldehyde

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With dihydrogen peroxide at 20℃; for 0.666667h; Time; Dakin Phenol Oxidation; Green chemistry;	98%
With dihydrogen peroxide In water at 20℃; for 2h; Dakin Phenol Oxidation; Green chemistry;	98%
With 7,8-difluoro-1,3-dimethyl-5-ethyl-4a-hydroperoxyalloxazine; dihydrogen peroxide; sodium hydrogencarbonate In methanol; water at 20℃; for 1h; Dakin oxidation;	92%

: 5075-52-5
1,2-bis(trimethylsilyloxy)benzene

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With methanol; 1,3-disulfonic acid imidazolium hydrogen sulfate at 20℃; for 0.0666667h; Green chemistry;	98%

: 17600-72-5
2-ethoxyanisole

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With hydrogenchloride In water at 250℃; under 37503.8 Torr; for 3h; Autoclave; Inert atmosphere; Green chemistry;	98%
With water; hydrogen bromide; Aliquat 336 at 105℃; for 9h; Catalytic behavior;	72%

: 91-16-7
1,2-dimethoxybenzene

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With 1,3-dimethyl-2-imidazolidinone; lithium diisopropyl amide In tetrahydrofuran; n-heptane; ethylbenzene at 185℃; for 12h;	97%
With hydrogen iodide at 25℃; for 24h; Inert atmosphere;	96%
With aluminium(III) iodide In acetonitrile for 0.5h; Heating; Var. solvent, time and substrate reagent ratio;	93%

: 6997-34-8
1-(4-hydroxy-3-methoxyphenyl)propan-1-ol

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With hydrogenchloride In water at 250℃; under 37503.8 Torr; for 3h; Sealed tube; Inert atmosphere;	97%

: 533-58-4
2-Iodophenol

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With copper(l) iodide; 8-quinolinol; potassium hydroxide In water; dimethyl sulfoxide; tert-butyl alcohol at 100℃; for 48h; Inert atmosphere;	95%
Stage #1: 2-Iodophenol With copper(l) iodide; 1,10-Phenanthroline; potassium hydroxide In water; dimethyl sulfoxide at 20 - 100℃; Inert atmosphere; Stage #2: With hydrogenchloride In water; dimethyl sulfoxide at 20℃; Inert atmosphere;	86%
With basolite C300; potassium hydroxide In water; dimethyl sulfoxide at 125℃; for 12h;	84%

: 94-71-3
2-Ethoxyphenol

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With aluminium(III) iodide In dimethyl sulfoxide; acetonitrile at 80℃; for 18h;	95%
With aluminium(III) iodide; dimethyl sulfoxide In acetonitrile at 80℃; for 18h;	95%
With aluminium(III) iodide; N,N-dimethyl-formamide dimethyl acetal In acetonitrile at 80℃; for 18h;	72%
With aluminium(III) iodide; N,N-dimethyl-formamide dimethyl acetal In acetonitrile at 80℃; for 18h;	72%
With oxygen; copper(II) perchlorate; ascorbic acid In water; acetone at 60℃; for 20h;	25%

: 1126-20-1
2-allyloxyphenol

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With boron dimethyl-trifluoro sulphide In dichloromethane at 0℃; for 0.0833333h;	95%

: 89466-08-0
2-hydroxyphenyl boronic acid

: 7722-84-1
dihydrogen peroxide

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With ammonium bicarbonate In water at 20℃; for 2h; Schlenk technique;	95%

: 33130-24-4
2-(2-phenylethoxy)phenol

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With aluminium(III) iodide In dimethyl sulfoxide; acetonitrile at 80℃; for 18h;	95%
With aluminium(III) iodide; dimethyl sulfoxide In acetonitrile at 80℃; for 18h;	95%
With aluminium(III) iodide In dimethyl sulfoxide; acetonitrile at 80℃; for 18h;	93%

: 5661-50-7
N-(phenoxy)acetamide

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; malonic acid In methanol at 25℃; for 12h; Catalytic behavior; Reagent/catalyst; Temperature; Solvent; Inert atmosphere;	95%

: 4812-20-8
2-Isopropoxyphenol

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With aluminium(III) iodide; diisopropyl-carbodiimide In acetonitrile at 80℃; for 18h;	94%
With aluminium(III) iodide; diisopropyl-carbodiimide In acetonitrile at 80℃; for 18h;	94%
With aluminium(III) iodide; calcium oxide In acetonitrile at 80℃; for 18h;	94%

: 2-bromo-6-hydroxycyclohex-2-en-1-one

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene	93%

: 6272-38-4
O-benzylcatechol

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With aluminium(III) iodide; dimethyl sulfoxide In acetonitrile at 80℃; for 18h;	93%
With aluminium(III) iodide; N,N-dimethyl-formamide dimethyl acetal In acetonitrile at 80℃; for 18h;	63%
With aluminium(III) iodide; N,N-dimethyl-formamide dimethyl acetal In acetonitrile at 80℃; for 18h;	63%

: 99-50-3
3,4-Dihydroxybenzoic acid

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With Na-X zeolite In water at 200℃; for 1h; Autoclave;	91%
With Cocos nucifera juice at 20℃; for 48h; Inert atmosphere;	88%
With cucumber juice at 30 - 35℃; for 48h; Inert atmosphere; Green chemistry;	85%

: 98-29-3
4-tert-Butylcatechol

A: 98-51-1
4-tert-butyltoluene

B: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With Nafion-H; toluene for 2h; Heating;	A 97 % Chromat. B 91%

: 98-29-3
4-tert-Butylcatechol

: 108-88-3
toluene

A: 98-51-1
4-tert-butyltoluene

B: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With Nafion-H for 2h; Heating;	A 97 % Chromat. B 91%

...Expand

: 165105-99-7
4-oxo-cyclohexyl 2,2-dimethylpropanoate

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With iodine; oxygen; dimethyl sulfoxide at 80℃; for 12h;	91%

: 583-63-1
ortoquinone

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With aluminium(III) iodide In acetonitrile for 1h; Heating;	90%
With sulphurous acid
Rate constant; pH 7.00; reaction with substrate reduced glucose oxidase;

: 118-93-4
o-hydroxyacetophenone

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With sodium percarbonate In tetrahydrofuran; water; N,N-dimethyl-formamide for 8h; ultrasonication;	90%
With sulfuric acid; dihydrogen peroxide; boric acid In tetrahydrofuran; water at 20℃; for 36h; Oxidation;	90%

: 75724-54-8
1-acetoxy-6-oxocyclohexa-2,4-dienyl propanoate

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether for 1h; Heating;	90%

: 7216-18-4
3,4-dihydro-2H-benzo[b][1,4]dioxepine

: 120-80-9
benzene-1,2-diol

Conditions

Conditions	Yield
With aluminum (III) chloride In benzene for 4h; Solvent; Time; Temperature; Reflux;	90%

: 120-80-9
benzene-1,2-diol

: 95-54-5
1,2-diamino-benzene

: 92-82-0
Phenazin

Conditions

Conditions	Yield
In water at 210℃; for 0.25h; Microwave irradiation;	100%
at 200℃;
at 200 - 210℃; in geschlossenen Rohr;
With potassium dichromate; acetic acid for 24h; Reflux;

: 120-80-9
benzene-1,2-diol

: 98-80-6
phenylboronic acid

: 5747-23-9
2-phenyl-1,3,2-benzodioxaborole

Conditions

Conditions	Yield
at 80℃; for 1h;	100%
for 0.166667h; Schlenk technique;	96%
In dichloromethane; ethyl acetate at 20℃;	81%

: 120-80-9
benzene-1,2-diol

: 17345-77-6
1-bromo-3,4-dihydroxybenzene

Conditions

Conditions	Yield
With benzyltriphenylphosphonium peroxodisulfate; potassium bromide In acetonitrile for 3.5h; Heating;	100%
With tetrafluoroboric acid diethyl ether; N-Bromosuccinimide In acetonitrile at -30 - 20℃;	100%
With N-Bromosuccinimide; tetrafluoroboric acid In diethyl ether; acetonitrile regioselective reaction;	100%

: 120-80-9
benzene-1,2-diol

: 583-63-1
ortoquinone

Conditions

Conditions	Yield
With 2,2'-bipyridylchromium peroxide In benzene for 0.5h; Product distribution; Heating; effect of various chromium(VI) based oxidants;	100%
With barium ferrate(VI) In benzene for 0.7h; Product distribution; Heating;	100%
With 2,2'-bipyridylchromium peroxide In benzene for 0.5h; Heating;	100%

: 33842-02-3, 529510-96-1
dichloromethylenedimethyliminium chloride

: 120-80-9
benzene-1,2-diol

: 36156-21-5
Benzo[1,3]dioxol-2-ylidene-dimethyl-ammonium; chloride

Conditions

Conditions	Yield
at -20℃; for 1h; ball mill;	100%
In dichloromethane for 1h; Heating;

: 120-80-9
benzene-1,2-diol

: 143-15-7
1-dodecylbromide

: 42244-53-1
1,2-bisdodecyloxybenzene

Conditions

Conditions	Yield
With potassium carbonate In acetone for 48h; Williamson ether synthesis; Reflux;	100%
With potassium carbonate In acetone for 48h; Heating;	95%
With potassium carbonate; potassium iodide In acetone for 48h; Reflux;	95%

: 120-80-9
benzene-1,2-diol

: 105-36-2
ethyl bromoacetate

: 52376-09-7
ethyl 2-<2-<(ethoxycarbonyl)methoxy>phenoxy>acetate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 120h;	100%
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In acetonitrile for 8h; Heating;	95%
With potassium carbonate In N,N-dimethyl-formamide at 75 - 80℃; for 1.5h;	90%

: 120-80-9
benzene-1,2-diol

: 142841-88-1
1-(benzenesulfonyl)-3-methylimidazolium triflate

: 3905-43-9
1,2-bis<(benzenesulfonyl)oxy>benzene

Conditions

Conditions	Yield
With 1-methyl-1H-imidazole In tetrahydrofuran 1) 0 deg C, 30 min, 2) RT, 6 h;	100%

: 72142-16-6
(3-methyl-2-butenyl)trimethoxysilane

: 120-80-9
benzene-1,2-diol

: 121-44-8
triethylamine

: 114571-77-6
triethylammonium bis(catecholato)(3-methyl-2-butenyl)siliconate

Conditions

Conditions	Yield
at 45℃; for 5h;	100%

...Expand

: 2551-83-9
allyltrimethoxysilane

: 120-80-9
benzene-1,2-diol

: 121-44-8
triethylamine

: 114612-18-9
triethylammonium bis(pyrocatecholato)allylsilicate

Conditions

Conditions	Yield
for 5h; room temperature to 40 deg C;	100%
at 40℃; for 4h; Inert atmosphere; Sealed tube;	55%

...Expand

: 125715-25-5
(2-methyl-2-propenyl)trimethoxysilane

: 120-80-9
benzene-1,2-diol

: 121-44-8
triethylamine

: 125715-30-2
triethylammonium bis(catecholato)(2-methyl-2-propenyl)siliconate

Conditions

Conditions	Yield
at 45℃; for 5h;	100%

...Expand

: 13436-83-4
2-Butenyltrimethoxysilane

: 120-80-9
benzene-1,2-diol

: 121-44-8
triethylamine

: triethylammonium bis(catecholato)-2-butenylsiliconate

Conditions

Conditions	Yield
at 45℃; for 5h;	100%

...Expand

: 120-80-9
benzene-1,2-diol

: 161868-74-2
1,1-dichloro-5-aza-2,8-dioxa-1-phosphaV-dibenzo<9,9',11,11'-tetra-tert-butyl>-bicyclo<3.3.0>octadiene

: C34H44NO4P

Conditions

Conditions	Yield
In benzene for 24h; Ambient temperature;	100%

: 64248-62-0
3,4-Difluorobenzonitrile

: 120-80-9
benzene-1,2-diol

: 234113-44-1
2-cyanodibenzo[1,4]dioxine

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide; toluene at 125 - 130℃;	100%
With potassium carbonate In N,N-dimethyl-formamide; toluene at 130 - 135℃; Etherification; cyclization;	98%

: 120-80-9
benzene-1,2-diol

C6-C4 carboxylic acids; C6-C4 aldehydes; C6-C4 ketones; mixture of: C6-C4 carboxylic acids; C6-C4 aldehydes; C6-C4 ketones; mixture of

Conditions

Conditions	Yield
With ozone In water at 20℃; for 0.1h; pH=2; Oxidation; Formation of xenobiotics;	100%

: 120-80-9
benzene-1,2-diol

: 791-28-6
Triphenylphosphine oxide

: 62785-50-6
triphenyl(1,2-phenylenedioxy)phosphorane

Conditions

Conditions	Yield
at 70 - 80℃; for 2h;	100%

: 866252-03-1
(E)-(2-(phenyldiazenyl)phenyl)boronic acid

: 120-80-9
benzene-1,2-diol

: 2-[2-(phenylazo)phenyl]-1,3,2-benzodioxaborole

Conditions

Conditions	Yield
In toluene for 4h; Heating;	100%

: 120-80-9
benzene-1,2-diol

: 19812-60-3
tetraethylene glycol monoacrylate

: CH2CHC(O)(OCH2CH2)4OB(O2C6H4)

Conditions

Conditions	Yield
Stage #1: benzene-1,2-diol With Trimethyl borate In acetonitrile at 60℃; for 1h; Stage #2: tetraethylene glycol monoacrylate In acetonitrile for 2h; Further stages.;	100%

: 557-20-0
diethylzinc

: 120-80-9
benzene-1,2-diol

A: 74-84-0
ethane

B: 10586-34-2
zinc pyrocatecholate

Conditions

Conditions	Yield
react. of the educts in a molar ratio of 1:1;	A 100% B n/a

...Expand

: 11113-50-1
boric acid

: 120-80-9
benzene-1,2-diol

: 791-31-1
triphenylhydroxysilane

: 82172-55-2
2-triphenylsiloxy-1,3,2-benzodioxaborole

Conditions

Conditions	Yield
In benzene byproducts: H2O; azeotropic removal of water; elem. anal.;	100%

...Expand

: 121-43-7
Trimethyl borate

: 120-80-9
benzene-1,2-diol

: 19812-60-3
tetraethylene glycol monoacrylate

: CH2CHC(O)(OCH2CH2)4OB(O2C6H4)

Conditions

Conditions	Yield
In acetonitrile stirring of catechol and B(OMe)3 at 60 °C for 1h, addn of tetraethylene glycol monoacrylate, 2 h stirring; cooling, vac. evapn. at 40 °C for 24 h;	100%

...Expand

: 1048382-97-3
(E)-dihydroxy(2-{[4-(trifluoromethyl)phenyl]azo}phenyl)borane

: 120-80-9
benzene-1,2-diol

: (E)-2-(2-{[4-(trifluoromethyl)phenyl]azo}phenyl)-1,3,2-benzodioxaborole

Conditions

Conditions	Yield
In toluene for 16h; Heating;	100%

: 120-80-9
benzene-1,2-diol

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 76128-65-9
N-(trimethoxysilylmethyl)hexahydroazepin-2-one

: dicyclohexylammonium bis(1,2-catecholato-O,O')-[(2-oxohexahydroazepin-1-yl)methyl-C,O]silicate

Conditions

Conditions	Yield
In o-xylene at 130 - 140℃;	100%

...Expand

: 112-35-6
triethylene glucol monomethyl ether

: 6867-35-2
lithium tetramethanolatoborate

: 120-80-9
benzene-1,2-diol

: C20H34BO10(1-)*Li(1+)

Conditions

Conditions	Yield
Stage #1: triethylene glucol monomethyl ether; lithium tetramethanolatoborate for 24h; Reflux; Inert atmosphere; Stage #2: benzene-1,2-diol for 24h; Reflux; Inert atmosphere;	100%

...Expand

: 480424-86-0
9,9-didodecylfluorene-2,7-diboronic acid

: 120-80-9
benzene-1,2-diol

: 1446012-94-7
C49H64B2O4

Conditions

Conditions	Yield
In toluene Reflux; Inert atmosphere;	100%

: 11113-50-1
boric acid

: 120-80-9
benzene-1,2-diol

: 37737-62-5
tris(catecholato)diboron

Conditions

Conditions	Yield
In toluene Dean-Stark; Reflux;	100%

: 2,2'-dihydroxy-1,1'-binaphthyl-3,3'-diboronic acid

: 120-80-9
benzene-1,2-diol

: C32H20B2O6

Conditions

Conditions	Yield
With sodium sulfate In toluene at 50℃; Reflux;	100%

: 1445-45-0
Trimethyl orthoacetate

: 120-80-9
benzene-1,2-diol

: 51487-87-7
o-(1-methoxyethoxy)-phenol

Conditions

Conditions	Yield
With trifluoroacetic acid In dimethylsulfoxide-d6 at 20℃; for 1h;	100%

: 5419-55-6
Triisopropyl borate

: 22348-32-9, 63401-04-7, 112022-88-5, 112068-01-6
(S)-diphenylprolinol

: 120-80-9
benzene-1,2-diol

: C23H22BNO3

Conditions

Conditions	Yield
In toluene at 80℃; for 1h; Inert atmosphere;	100%
Stage #1: Triisopropyl borate; benzene-1,2-diol In toluene Inert atmosphere; Reflux; Stage #2: (S)-diphenylprolinol In toluene at 80℃; for 1h; Inert atmosphere; Reflux;	100%

...Expand

Pyrocatechol Chemical Properties

The Molecular Structure of Catechol (CAS NO.120-80-9):

Empirical Formula: C₆H₆O₂
Molecular Weight: 110.1106
Nominal Mass: 110 Da
IUPAC Name: benzene-1,2-diol
Appearance: Off-white powder
Average Mass: 110.1106 Da
Monoisotopic Mass: 110.036779 Da
Index of Refraction: 1.612
Molar Refractivity: 30.01 cm³
Molar Volume: 86.2 cm³
Surface Tension: 57.1 dyne/cm
Density: 1.275 g/cm³
Flash Point: 137.2 °C
Enthalpy of Vaporization: 50.21 kJ/mol
Boiling Point: 245.5 °C at 760 mmHg
Melting Point: 103-106 °C
Vapour Pressure: 0.0183 mmHg at 25°C
Water Solubility: 430 g/L (20 ºC)
Stability: Stable. Substances to be avoided include acid chlorides, acid anhydrides, bases, oxidizing agents, nitric acid. Light sensitive; may discolour on exposure to air. Combustible.
Synonyms: 1,2-Benzenediol (pyrocatechol) ; 1,2-benzenediol[qr] ; 1,2-dihydroxybenzene[qr] ; 2-Hydroxyphenol ; 2-hydroxyphenol[qr] ; ai3-03995[qr] ; Benzene, o-dihydroxy- ; benzene,1,2-dihydroxy-

Pyrocatechol Uses

Approximately 50% of synthetic catechol (CAS NO.120-80-9) is consumed in the production of pesticides, the remainder being used as a precursor to fine chemicals such as perfumes and pharmaceuticals. Catechol (CAS NO.120-80-9) is a common building block in organic synthesis. Several industrially significant flavors and fragrances are prepared starting from Catechol (CAS NO.120-80-9).

Pyrocatechol Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	oral	100mg/kg (100mg/kg)		International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
dog	LD50	oral	130mg/kg (130mg/kg)		International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
dog	LDLo	intravenous	40mg/kg (40mg/kg)		"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 62, 1955.
frog	LDLo	parenteral	160mg/kg (160mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 166, Pg. 437, 1932.
frog	LDLo	subcutaneous	160mg/kg (160mg/kg)		"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 62, 1955.
guinea pig	LD50	oral	210mg/kg (210mg/kg)		Advances in Food Research. Vol. 3, Pg. 197, 1951.
guinea pig	LDLo	intraperitoneal	150mg/kg (150mg/kg)		"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 62, 1955.
guinea pig	LDLo	subcutaneous	200mg/kg (200mg/kg)		"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 62, 1955.
mammal (species unspecified)	LD50	oral	240mg/kg (240mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 15, Pg. 136, 1979.
mouse	LD50	intraperitoneal	68mg/kg (68mg/kg)		Pharmacology and Toxicology Vol. 64, Pg. 247, 1989.
mouse	LD50	oral	260mg/kg (260mg/kg)		Advances in Food Research. Vol. 3, Pg. 197, 1951.
mouse	LD50	subcutaneous	247mg/kg (247mg/kg)		Industrial Health. Vol. 5, Pg. 143, 1967.
rabbit	LD50	skin	800mg/kg (800mg/kg)	SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE	American Industrial Hygiene Association Journal. Vol. 37, Pg. 596, 1976.
rabbit	LDLo	oral	200mg/kg (200mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BLOOD: LEUKOPENIA BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN	"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2A, Pg. 2585, 1981.
rabbit	LDLo	subcutaneous	225mg/kg (225mg/kg)		Journal of Agricultural and Food Chemistry. Vol. 17, Pg. 497, 1969.
rat	LD50	oral	260mg/kg (260mg/kg)		Advances in Food Research. Vol. 3, Pg. 197, 1951.
rat	LDLo	subcutaneous	110mg/kg (110mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie

Pyrocatechol Consensus Reports

Catechol (CAS NO.120-80-9) is reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Pyrocatechol Safety Profile

Hazard Codes: Harmful Xn
Risk Statements: 21/22-36/38
R21/22: Harmful in contact with skin and if swallowed
R36/38: Irritating to eyes and skin
Safety Statements: 22-26-37
S22: Do not breathe dust
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S37: Wear suitable gloves
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 2
RTECS: UX1050000
HazardClass: 6.1
PackingGroup: III
Poison by ingestion, subcutaneous, intraperitoneal, intravenous, and parenteral routes. Moderately toxic by skin contact. Experimental reproductive effects. Can cause dermatitis on skin contact. An allergen.Questionable carcinogen. Systemic effects similar to those of phenol. Combustible when exposed to heat or flame; can react vigorously with oxidizing materials. Hypergolic reaction with concentrated nitric acid. To fight fire, use water, CO₂, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.

Pyrocatechol Standards and Recommendations

OSHA PEL: TWA 5 ppm (skin)
ACGIH TLV: TWA 5 ppm (skin); Animal Carcinogen

Pyrocatechol Specification

1、Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
2、Handling and Storage
Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Take precautionary measures against static discharges. Use only in a chemical fume hood.
Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container. Material darkens in color on storage.

Product Name

Pyrocatechol

Synthetic route

Pyrocatechol Chemical Properties

Pyrocatechol Uses

Pyrocatechol Toxicity Data With Reference

Pyrocatechol Consensus Reports

Pyrocatechol Safety Profile

Pyrocatechol Standards and Recommendations

Pyrocatechol Specification

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