Conditions | Yield |
---|---|
evaporated, with excess of ICl; | 100% |
evaporated, with excess of ICl; | 100% |
Conditions | Yield |
---|---|
With hydrogenchloride In neat (no solvent) passing dry HCl over NaNO3 at 130°C over period of 2 to 3 h;; slow heating to 400°C to get rid of HNO3 traces;; | 100% |
With HCl In neat (no solvent) passing dry HCl over NaNO3 at 130°C over period of 2 to 3 h;; slow heating to 400°C to get rid of HNO3 traces;; | 100% |
dihydrogen peroxide
chlorine
sodium hydroxide
oxygen
B
sodium chloride
Conditions | Yield |
---|---|
In water H2O2 soln. poured onto porous glass plate within the singlet O2 generator (closed glass system, under Ar), spent liquid discarded into the lower flask, Cl2 (1-2 kPa) admitted, alkali soln. poured in, evolution of singlet O2 over a period of 12-16 min.; luminiscence spectroscopy, calorimetry; | A 100% B n/a |
Conditions | Yield |
---|---|
With sodium In neat (no solvent) Ar-atmosphere; stirring (-70°C, 1 h); evapn., extg. (pentane); elem. anal.; | A n/a B 100% |
sodium tetrahydroborate
B
sodium chloride
Conditions | Yield |
---|---|
With 1,3-dioxolane In further solvent(s) (N2); salts mixt. (1/1 molar ratio) stirred at 25-74°C for 1-48 h in 1,3-dioxolane; heated (vac.); | A 99% B n/a |
With isopropylamine In further solvent(s) (N2); salts mixt. (1/1 molar ratio) stirred at 25-34°C for 2-8 hin isopropylamine; heated (vac.); | A 97-100 B n/a |
With C4H8O In tetrahydrofuran (N2); salts mixt. (1/1 molar ratio) stirred at 25-67°C for 1-48 h in THF; heated (vac.); | |
With diethyl ether In diethyl ether (N2); salts mixt. (1/1 molar ratio) stirred at 35°C for 1-48 h in Et2O; heated (vac.); | |
With 1,2-dimethoxyethane In 1,2-dimethoxyethane (N2); salts mixt. (1/1 molar ratio) stirred at 0-85°C for 1-72 hin monoglyme; heated (vac.); |
hydrogenchloride
sodium carbonate
A
H2CO3*CH3CH2OCH2CH3
B
sodium chloride
Conditions | Yield |
---|---|
In diethyl ether | A 99% B n/a |
In diethyl ether | A 99% B n/a |
hydrogenchloride
sodium carbonate
A
Kohlenstoffoxid-bis-(hydroxid)-mono-dimethylaetherat
B
sodium chloride
Conditions | Yield |
---|---|
In Dimethyl ether | A 99% B n/a |
In Dimethyl ether | A 99% B n/a |
Conditions | Yield |
---|---|
In tetrahydrofuran Ar-atmosphere; stirring (-78°C, 18 h); evapn. (vac.), drying (dynamic vac., 40 h), extg. (pentane), filtering, subliming (55°C); | A 52% B 99% |
Conditions | Yield |
---|---|
In tetrahydrofuran byproducts: N2; High Pressure; CuCl2 and NaN3 ground, placed into a stainless steel reactor, solvent added, sealed, heated to ca. 50°C, ca. 100°C, and 185°C with regulated rates (the total react. time of ca. 3-5 d); cooled to room temp., dried (vac.), NaCl sepd. with MeOH under N2, filtered, dried (vac.); obtained as nanocrystals; | A 98% B n/a |
In toluene byproducts: N2; High Pressure; CuCl2 and NaN3 ground, placed into a stainless steel reactor, solvent added, sealed, heated to ca. 50°C, ca. 100°C, and 185°C with regulated rates (the total react. time of ca. 3-5 d); cooled to room temp., dried (vac.), NaCl sepd. with MeOH under N2, filtered, dried (vac.); obtained as nanocrystals; | A 85% B n/a |
In m-xylene at 116-135°C for 14 h to 1.5 d; not isolated, detected by IR, XRD; |
Conditions | Yield |
---|---|
With air In tetrahydrofuran stirred for 18 h under dry air; centrifuged, washed with benzene and water (Yb2O3), naphthalene detd. by GLC in the organic layer, aq. soln. contains NaCl; | A 98% B 98% C 96% |
Conditions | Yield |
---|---|
In methanol; water Na addn. to methanolic soln. of Si-compd., refluxing (1 h), methanolic soln. of Cu-compd. addn., refluxing (2 h), MeOH distillation off with simultaneous addn. of butanol, refluxing (15 min); NaCl filtration off, solvent evapn. to crystn., after 48 h crystals sepn., drying (20°C); elem. anal.; | A 97.6% B 98% |
ethanol
3-(trimethoxysilyl)propan-1-amine
sodium hydroxide
B
sodium chloride
Conditions | Yield |
---|---|
In methanol; water Si-compd. dissoln. in MeOH, aq. soln. of NaOH addn., refluxing (1 h), soln. of Cu-compd. in MeOH addn., refluxing (30 min), MeOH distillation off with simultaneous addn. of EtOH; NaCl filtration off, solvent removing; elem. anal.; | A 93% B 98% |
2,2,4,4,6,6-hexamethyl-1,3,5,2,4,6-trithiatristanninane
N-chloro-p-chlorobenzenesulfonamide sodium salt
A
CH3OSn(CH3)2S(NSO2C6H4Cl)Sn(CH3)2SSn(CH3)2NHSO2C6H4Cl
B
sulfur
C
sodium chloride
Conditions | Yield |
---|---|
In methanol soln. of N-compd. addn. to soln. of Sn compd. (vacuum, stirring), heating (50°C, 30 min); mixture cooling (ice bath), ppt. filtration off and extracting with water to remove NaCl and with acetone to remove S, alcoholic filtrate vacuumevapn., residue treating with diethyl ether, soln. decanting and vacuum evapn.; elem. anal.; | A 92% B 33% C 98% |
Conditions | Yield |
---|---|
In ethanol; water elem. anal.; | A 90.3% B 96% |
(vinyl)trimethoxylsilane
sodium hydroxide
butan-1-ol
B
sodium chloride
Conditions | Yield |
---|---|
In methanol; water soln. of NaOH addn. to soln. of Si-compd., refluxing, soln. of Mn-compd.addn., refluxing, MeOH distillation off with simultaneous addn. of buta nol; NaCl filtration off, solvent evapn.; elem. anal.; | A 87% B 95.5% |
tributyltin chloride
sodium
benzildioxime
A
C6H5C(NOH)C(NO)C6H5Sn(CH2CH2CH2CH3)3
B
sodium chloride
Conditions | Yield |
---|---|
In isopropyl alcohol; benzene strictly anhydrous conditions; addn. of Na to excess of i-PrOH, refluxing (0.5 h), cooling, addn. of oxime, refluxing (2 h), cooling, addn. of stoichiom. amt. of Sn compound in benzene, refluxing (2 h); sovent removal (reduced pressure), filtration off of NaCl, crystn. (benzene/petroleum ether); elem. anal.; | A 95% B n/a |
CYANAMID
cyanogen chloride
A
sodium N-cyanoisourea
B
sodium dicyanamide
C
sodium chloride
Conditions | Yield |
---|---|
With sodium hydroxide In water at 70 - 75℃; under 1050.11 Torr; pH=7.2 - 8.0; Purification / work up; | A n/a B 94% C n/a |
sodium tetrahydroborate
aluminium trichloride
A
aluminum(III) fluoride
B
sodium chloride
C
diborane
Conditions | Yield |
---|---|
In further solvent(s) soln. NaBH4 in triglyme was added slowly for 2-3 h at room temp. to BF3-triglyme, AlCl3 in triglyme; B2H6 was absorbed with THF; | A n/a B n/a C 94% |
sodium tetrahydroborate
aluminium trichloride
A
aluminum(III) fluoride
B
sodium chloride
C
diborane
Conditions | Yield |
---|---|
In further solvent(s) soln. NaBH4 in triglyme was added slowly for 2-3 h at room temp. to BF3-tetraglyme, AlCl3 in triglyme; B2H6 was absorbed with THF; | A n/a B n/a C 94% |
Conditions | Yield |
---|---|
In tetrahydrofuran soln. of InCl3 and Na-compd. mixed,, stirred for 18h; molar ratio In-compd : Li-compd = 1:3; exclusion of air and moisture; solvent removed, pentane distilled onto poducts, sublimation; elem. anal.; | A 65.9% B 83.9% C 94% |
sodium nitrite
CH(O)C6H2(CH3)(CO)ORh(P(C6H5)3)2NO2
B
sodium chloride
Conditions | Yield |
---|---|
With H2O In dichloromethane; acetone byproducts: CH3C6H4NH2*HCl; stirring (0.5 h), evapn. (reduced pressure); filtering, washing (H2O), drying (vac.); elem. anal.; | A 94% B n/a |
Conditions | Yield |
---|---|
In methanol; ethanol elem. anal.; | A 42.5% B 94% |
sodium tetrafluoroborate
trans-bis(triphenylphosphine)palladium dichloride
p-methoxyphenylisocyanide
trans-{(PPh3)2Pd(CNC6H4-p-OMe)Cl}BF4
B
sodium chloride
Conditions | Yield |
---|---|
In acetone under inert gas; dropwise addn. of the isocyanide in acetone to the suspn. of the Pd complex in acetone in presence of NaBF4 at room temp.; stirring for 1 h; solvent removed, residue dissolved in CH2Cl2; soln. filtered and concd., addn. of Et2O yields the solid; elem. anal.; | A 93% B n/a |
sodium tetrafluoroborate
trans-dichlorobis(triphenylphosphine)platinum(II)
Cyclohexyl isocyanide
trans-{(PPh3)2Pt(CNC6H11)Cl}BF4
B
sodium chloride
Conditions | Yield |
---|---|
In acetone under inert gas; dropwise addn. of the isocyanide in acetone to the suspn. of the Pt complex in acetone in presence of NaBF4 at room temp.; stirring for 1 h; solvent removed, residue dissolved in CH2Cl2; soln. filtered and concd., addn. of Et2O yields the solid; elem. anal.; | A 92% B n/a |
Conditions | Yield |
---|---|
-78°C; | A n/a B 92% |
picoline
indium(III) chloride
sodium 3,5-di-tert-butyl-o-benzosemiquinolate
A
[InCl(((CH3)3C)2C6H2O2)(CH3C5H4N)2]
B
sodium chloride
Conditions | Yield |
---|---|
In tetrahydrofuran byproducts: H2; N2, blue soln. of semiquinone sodium salt added dropwise over 1 h to a soln. of In-salt, stirred for 2 h at room temp., NaCl removed from intermediate products by filtrn., excess 4-picoline added to the filtrate; collected, dried, recrystd. (toluene/THF); elem. anal.; formn. of In(I)and other species also discussed; | A 50% B 92% |
chlorobis[3-(dimethylamino)propyl]aluminium
azidobis[3-(dimethylamino)propyl]aluminium
B
sodium chloride
Conditions | Yield |
---|---|
In tetrahydrofuran N2-atmosphere; refluxing (15 h); evapn. (vac.), sublimation (100°C, 10E-04 Torr); | A 92% B n/a |
Conditions | Yield |
---|---|
With diethyl malonate In ethanol; toluene Na was dissolved in EtOH at room temp., diethylmalonate was added, toluene was added, soln. phenacyl chloride in toluene was added at room temp.; ppt. was centrifugated and washed with EtOH; powder X-ray diffraction; | 92% |
1-chloro-2-chloromethyl-1,1,2,2-tetramethyl-disilane
A
(η5-C5H5)Fe(CO)2SiMe2SiMe2CH2Fe(CO)2(η5-C5H5)
B
sodium chloride
Conditions | Yield |
---|---|
In tetrahydrofuran to THF soln. (Fp)Na was added to THF soln. ClCH2SiMe2SiMe2Cl at ambienttemp. and stirred for 2 h; solvent was removed and product was extd. into hexane, solvent was evapd. and residue was chromed. on silica using hexane as eluent; elem. anal.; | A 91% B n/a |
sodium tetrahydroborate
sodium tetrafluoroborate
aluminium trichloride
A
aluminum(III) fluoride
B
sodium chloride
C
diborane
Conditions | Yield |
---|---|
In further solvent(s) soln. NaBH4 in triglyme (tetraglyme) was added slowly for 2-3 h at roomtemp. to NaBF4 and AlCl3 in triglyme (tetraglyme); B2H6 was absorbed with THF; | A n/a B n/a C 90% |
Conditions | Yield |
---|---|
In water NH3 passed into a soln. of (NH4)2CO3-NaCl until satn.; product free of Cl and NH3; | 100% |
In water NH3 passed into a soln. of (NH4)2CO3-NaCl until satn.; product free of Cl and NH3; | 100% |
Conditions | Yield |
---|---|
In neat (no solvent) stoichiometric mixture, sealed Ta container, 800-850°C; | 100% |
In neat (no solvent) heating of stoich. amts. of reagents in a sealed Ta tube at 700-860°C for 2-3 weeks; identified by single crystal X-ray diffraction; | >90 |
In neat (no solvent) mixt. of Zr, ZrCl4, NaCl and Be was sealed under Ar in Nb or Ta ampule; heated; |
Conditions | Yield |
---|---|
In water pptn. from H2SiF6 soln. (12%) by NaCl soln. (60% excess);; | 100% |
In water pptn. from H2SiF6 soln. (12%) by NaCl soln. (60% excess);; | 100% |
In water pptn. from H2SiF6 soln. (12%) by NaCl soln. (20% excess);; | 90% |
Conditions | Yield |
---|---|
In neat (no solvent) gradual addn. of NaClO3 to melt of U3O8 and NaCl; very slow, but complete react.;; | 100% |
In neat (no solvent) gradual addn. of NaClO3 to melt of U3O8 and NaCl; very slow, but complete react.;; | 100% |
Conditions | Yield |
---|---|
In neat (no solvent) using same amt. of NaCl and Na2CO3;; | 100% |
In neat (no solvent) using same amt. of NaCl and Na2CO3;; | 100% |
Conditions | Yield |
---|---|
In water at 353 K, in diaphragm electrolyzer, at pH 2.1-3.0; | 100% |
In water byproducts: NaOCl; at 353 K, in diaphragm electrolyzer, at pH 4.0-6.0; | 98.1% |
In water byproducts: NaOCl; at 353 K, in diaphragm electrolyzer, at pH 6.0-8.0; | 96% |
m-carboran-9-yl(phenyl)iodonium tetrafluoroborate
sodium chloride
A
iodobenzene
B
9-chloro-m-carborane
Conditions | Yield |
---|---|
In chloroform; water mixt. of aryl(m-carboran-9-yl)iodonium tetrafluoroborate, NaF, water and chloroform was vigorously stirred under reflux at 56°C, 1 h; internal standard (chlorobenzene) added and org. layer was analysed by GLC; | A 100% B 100% |
4-methoxyphenyl(m-carboran-9-yl)iodonium tetrafluoroborate
sodium chloride
A
9-iodo-m-carborane
B
9-chloro-m-carborane
C
para-iodoanisole
D
methoxybenzene
Conditions | Yield |
---|---|
In chloroform; water mixt. of aryl(m-carboran-9-yl)iodonium tetrafluoroborate, NaCl, water and chloroform was vigorously stirred under reflux at 56°C, 2-2.5 h; internal standard (chlorobenzene) added and org. layer was analysed by GLC; | A 0% B 100% C 100% D 0% |
4-fluorophenyl(m-carboran-9-yl)iodonium tetrafluoroborate
sodium chloride
A
fluorobenzene
B
9-iodo-m-carborane
C
9-chloro-m-carborane
D
4-fluoro-1-iodobenzene
Conditions | Yield |
---|---|
In chloroform; water mixt. of aryl(m-carboran-9-yl)iodonium tetrafluoroborate, NaCl, water and chloroform was vigorously stirred under reflux at 56°C, 2-2.5 h; internal standard (chlorobenzene) added and org. layer was analysed by GLC; | A 0% B 0% C 100% D 100% |
3-nitrophenyl(m-carboran-9-yl)iodonium tetrafluoroborate
sodium chloride
A
m-iodonitrobenzene
B
9-iodo-m-carborane
C
9-chloro-m-carborane
D
nitrobenzene
Conditions | Yield |
---|---|
In chloroform; water mixt. of aryl(m-carboran-9-yl)iodonium tetrafluoroborate, NaCl, water and chloroform was vigorously stirred under reflux at 56°C, 2-2.5 h; internal standard (chlorobenzene) added and org. layer was analysed by GLC; | A 100% B 0% C 100% D 0% |
2,4,6-trimethylphenyl(m-carboran-9-yl)iodonium tetrafluoroborate
sodium chloride
A
9-iodo-m-carborane
B
9-chloro-m-carborane
C
iodomesitylene
D
1,3,5-trimethyl-benzene
Conditions | Yield |
---|---|
In chloroform; water mixt. of aryl(m-carboran-9-yl)iodonium tetrafluoroborate, NaF, water and chloroform was vigorously stirred under reflux at 56°C, 2.5 h; internal standard (chlorobenzene) added and org. layer was analysed by GLC; | A 0% B 100% C 100% D 0% |
Conditions | Yield |
---|---|
In water; acetone inert atm.; satd. aq. NaCl added slowly with stirring to a soln. of the complex in acetone at 20°C; ppt. filtered off, washed with water and dried in vacuo; recrystn. from acetone; elem. anal.; | 100% |
Conditions | Yield |
---|---|
In ethanol xanthene-compound was added to Mn(CH3CO2)2*4H2O in abs. ethanol, the soln. was refluxed in air for 2 h, cooled, aq. satd. NaCl was added, the mixt. was stirred for 10 min; extd. with CH2Cl2, the organic layer was washed with water, dried over MgSO4, the solid was rotary evapd.; elem. anal.; | 100% |
sodium chloride
Conditions | Yield |
---|---|
In acetone Inert atmosphere; | 100% |
Conditions | Yield |
---|---|
Stage #1: C56H70Co2N4O4 With oxygen; toluene-4-sulfonic acid In dichloromethane for 24h; Stage #2: sodium chloride In water | 100% |
Conditions | Yield |
---|---|
at 450℃; for 144h; Inert atmosphere; Milling; | 100% |
Conditions | Yield |
---|---|
Stage #1: 15-crown-5; sodium chloride In water at 20℃; for 12h; Stage #2: zinc(II) chloride In ethanol for 12h; Reflux; | 100% |
15-crown-5
sodium chloride
Conditions | Yield |
---|---|
Stage #1: 15-crown-5; sodium chloride In water at 20℃; for 12h; Stage #2: iron(III) chloride hexahydrate In ethanol for 12h; Reflux; | 100% |
Conditions | Yield |
---|---|
In acetone at 20℃; | 100% |
sodium chloride
Conditions | Yield |
---|---|
With DOWEX 50 WX8 100-200 ion exchange resin In acetone | 99.5% |
sodium chloride
Conditions | Yield |
---|---|
With DOWEX 50 WX8 100-200 ion exchange resin In acetone | 99.5% |
Conditions | Yield |
---|---|
In water to aq. soln. Na2(PdCl4), prepared in situ by react. PdCl2 and NaCl, was added pyridine-2-carboxylic acid in water and stirred for 2 h; ppt. was filtered, washed with water and acetone, and dried in vacuo; elem. anal.; | 99% |
bis(diphenylphosphino)methane monooxide
sodium chloride
PdCl2((C6H5)2PCH2P(O)(C6H5)2)2
Conditions | Yield |
---|---|
In methanol; dichloromethane evapn., extg. (CH2Cl2), filtering, pptn. on concg. and ether addn. (-15°C, overnight), washing (ether), drying (vac.); | 99% |
Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.
Both the IUPAC name and product name of this chemical are the same which is called Sodium chloride. With the CAS register number 7647-14-5. The substance is an ionic compound with the formula NaCl. Sodium chloride is soluble in water and glycerol, but insoluble in alcohol. Sodium chloride is stable. You must avoid contact with strong acids which when in contact may evolve chlorine gas. Sodium chloride will become corrosive to metals when wet. What's more, its EINECS number is 231-598-3.
Physical properties about Sodium chloride are: Water solution of Sodium chloride is alkaline with the PH value 6.7-7.3. It is soluble in water, salty, and has low thermal conductivity. In addition, it won't conduct electricity. Sodium chloride has a strong hygroscopicity and can deliquesce easily. Rock salt is the most widely content in salt mine.
Preparation of Sodium chloride: Salt is currently mass-produced by evaporation of seawater or brine from other sources, such as brine wells and salt lakes, and by mining rock salt, called halite. Using sold salt dissoves in distilled water. The mixture is boiled after addition of sodium hydroxide, then is stored overnight and filtered. You should keep filtrate clean and then cool down it simultaneously put into pure HCl gas to make the mixture saturated. After that, crystal of Sodium chloride will separate out. There are also three methods of Sodium chloride production and purification: brine solution, rock salt mining, and the open pan or grainer process:
To produce Sodium chloride from brine, water is pumped into the salt deposit and the saturated salt solution containing 26% salt, 73.5% water, and 0.5% impurities, is removed. Hydrogen sulfide is removed by aeration, and oxidation with chlorine. Calcium (Ca2+), magnesium (Mg2+), and iron (Fe3+) are precipitated as the carbonates using soda ash and are removed in a settling tank. The brine solution can be sold directly or it can be evaporated to give salt of 99.8% purity.
Rock salt is produced from deep mines so that the salt is taken directly from the deposit. Salt obtained by this method is 98.5 to 99.4% pure.
In the open pan or grainer salt method, hot brine solution is held in an open pan approximately 4 to 6 meters wide, 45 to 60 meters long, and 60 cm deep at 96°C. Flat, pure sodium chloride crystals form on the surface and fall to the bottom and are raked to a centrifuge, separated from the brine, and dried. A purity of 99.98% is obtained. A vacuum pan system is also available.
Uses of Sodium chloride: As the major ingredient in edible salt, Sodium chloride is commonly used as a condiment and food preservative. Sodium chloride can manufacture pulp and paper, to setting dyes in textiles and fabric, to producing soaps, detergents, and other bath products. Sodium chloride is sometimes used as a cheap and safe desiccant because of its hygroscopic properties.
Salt also is added to secure the soil and to provide firmness to the foundation on which highways are built. Road salt ends up in fresh water bodies and could harm aquatic plants and animals by disrupting their osmoregulation ability. The industrial uses of salt include, in descending order of quantity consumed, various applications, oil and gas exploration, textiles and dyeing, pulp and paper, metal processing, tanning and leather treatment, and rubber manufacture. It is used to flocculate and increase the density of the drilling fluid to overcome high downwell gas pressures.
In textiles and dyeing, salt is used as a brine rinse to separate organic contaminants, to promote “salting out” of dyestuff precipitates, and to blend with concentrated dyes to standardize them. In metal processing, salt is used in concentrating uranium ore into uranium oxide (yellow cake). It also is used in processing aluminium, beryllium, copper, steel and vanadium. In the pulp and paper industry, salt is used to bleach wood pulp. It also is used to make sodium chlorate. In rubber manufacture, salt is used to make buna, neoprene and white rubber types.
When you are using Sodium chloride, you should be very cautious about it. It is irritant and harmful if swallowed. In addition, Sodium chloride is irritating to eyes, respiratory system and skin. You must avoid contact with skin and eyes. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact or use Sodium chloride, please wear suitable protective clothing.
You can still convert the following datas into molecular structure:
(1)Canonical SMILES: [Na+].[Cl-]
(2)InChI: InChI=1S/ClH.Na/h1H;/q;+1/p-1
(3)InChIKey: FAPWRFPIFSIZLT-UHFFFAOYSA-M
Toxicity data of Sodium chloride:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | intravenous | 2gm/kg (2000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 21, Pg. 119, 1886. |
guinea pig | LDLo | intraarterial | 300mg/kg (300mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928. | |
guinea pig | LDLo | intravenous | 300mg/kg (300mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928. | |
guinea pig | LDLo | parenteral | 300mg/kg (300mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928. | |
guinea pig | LDLo | subcutaneous | 2160mg/kg (2160mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. | |
human | TDLo | oral | 12357mg/kg/23 (12357mg/kg) | VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION | American Journal of Digestive Diseases. Vol. 21, Pg. 180, 1954. |
man | LDLo | oral | 1gm/kg (1000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Mayo Clinic Proceedings. Vol. 65, Pg. 1587, 1990. |
mouse | LD50 | intracervical | 131mg/kg (131mg/kg) | Tohoku Yakka Daigaku Kenkyu Nempo. Annual Report of the Tohoku College of Pharmacy. Vol. 27, Pg. 131, 1980. | |
mouse | LD50 | intraperitoneal | 2602mg/kg (2602mg/kg) | Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963. | |
mouse | LD50 | intravenous | 645mg/kg (645mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 445, 1957. | |
mouse | LD50 | oral | 4gm/kg (4000mg/kg) | Farmaco, Edizione Pratica. Vol. 27, Pg. 19, 1972. | |
mouse | LD50 | subcutaneous | 3gm/kg (3000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 445, 1957. | |
rabbit | LD50 | skin | > 10gm/kg (10000mg/kg) | BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 20-3/1971, | |
rabbit | LDLo | intravenous | 1100mg/kg (1100mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) CARDIAC: OTHER CHANGES | Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 21, Pg. 119, 1886. |
rabbit | LDLo | oral | 8gm/kg (8000mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. | |
rat | LC50 | inhalation | > 42gm/m3/1H (42000mg/m3) | BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 20-3/1971, | |
rat | LD50 | oral | 3gm/kg (3000mg/kg) | Toxicology and Applied Pharmacology. Vol. 20, Pg. 57, 1971. | |
rat | LDLo | subcutaneous | 3500mg/kg (3500mg/kg) | BEHAVIORAL: IRRITABILITY | Endocrinology Vol. 24, Pg. 523, 1939. |
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